Calcium_motive_p-type_ATPase_putative/GeneDB:LmjF.35.2080

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

calcium motive p-type ATPase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X978_LEIDO

TriTrypDb:

LdBPK_352080.1 , LdCL_350026000 , LDHU3_35.2690

Length:

1109

Annotations

LeishMANIAdb annotations

Homologous to animal ER-localized Ca2+ ATPases. Localization: ER (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 12

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 5

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	12
GO:0110165	cellular anatomical entity	1	12
GO:0005886	plasma membrane	3	1

Expansion

Sequence features

A0A3S7X978

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X978

Function

Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	1
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006816	calcium ion transport	7	1
GO:0006873	intracellular monoatomic ion homeostasis	4	1
GO:0006874	intracellular calcium ion homeostasis	7	1
GO:0006875	obsolete intracellular metal ion homeostasis	6	1
GO:0009987	cellular process	1	1
GO:0019725	cellular homeostasis	2	1
GO:0030001	metal ion transport	6	1
GO:0030003	intracellular monoatomic cation homeostasis	5	1
GO:0034220	monoatomic ion transmembrane transport	3	1
GO:0042592	homeostatic process	3	1
GO:0048878	chemical homeostasis	4	1
GO:0050801	monoatomic ion homeostasis	5	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0055065	obsolete metal ion homeostasis	7	1
GO:0055074	calcium ion homeostasis	8	1
GO:0055080	monoatomic cation homeostasis	6	1
GO:0055082	intracellular chemical homeostasis	3	1
GO:0055085	transmembrane transport	2	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0070588	calcium ion transmembrane transport	6	1
GO:0072503	obsolete cellular divalent inorganic cation homeostasis	6	1
GO:0072507	obsolete divalent inorganic cation homeostasis	7	1
GO:0098655	monoatomic cation transmembrane transport	4	1
GO:0098660	inorganic ion transmembrane transport	4	1
GO:0098662	inorganic cation transmembrane transport	5	1
GO:0098771	inorganic ion homeostasis	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0005215	transporter activity	1	2
GO:0005388	P-type calcium transporter activity	4	1
GO:0008324	monoatomic cation transmembrane transporter activity	4	2
GO:0015075	monoatomic ion transmembrane transporter activity	3	2
GO:0015085	calcium ion transmembrane transporter activity	6	1
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	2
GO:0015399	primary active transmembrane transporter activity	4	2
GO:0015662	P-type ion transporter activity	4	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3	2
GO:0022804	active transmembrane transporter activity	3	2
GO:0022853	active monoatomic ion transmembrane transporter activity	4	2
GO:0022857	transmembrane transporter activity	2	2
GO:0022890	inorganic cation transmembrane transporter activity	4	2
GO:0042626	ATPase-coupled transmembrane transporter activity	2	2
GO:0046873	metal ion transmembrane transporter activity	5	1
GO:0140358	P-type transmembrane transporter activity	3	1
GO:0140657	ATP-dependent activity	1	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	106	110	PF00656	0.595
CLV_C14_Caspase3-7	116	120	PF00656	0.537
CLV_C14_Caspase3-7	489	493	PF00656	0.629
CLV_C14_Caspase3-7	709	713	PF00656	0.683
CLV_NRD_NRD_1	1027	1029	PF00675	0.478
CLV_NRD_NRD_1	1105	1107	PF00675	0.603
CLV_NRD_NRD_1	272	274	PF00675	0.336
CLV_NRD_NRD_1	391	393	PF00675	0.384
CLV_NRD_NRD_1	688	690	PF00675	0.512
CLV_NRD_NRD_1	738	740	PF00675	0.351
CLV_NRD_NRD_1	796	798	PF00675	0.348
CLV_NRD_NRD_1	802	804	PF00675	0.355
CLV_PCSK_KEX2_1	1100	1102	PF00082	0.553
CLV_PCSK_KEX2_1	1107	1109	PF00082	0.576
CLV_PCSK_KEX2_1	306	308	PF00082	0.425
CLV_PCSK_KEX2_1	382	384	PF00082	0.364
CLV_PCSK_KEX2_1	537	539	PF00082	0.326
CLV_PCSK_KEX2_1	548	550	PF00082	0.326
CLV_PCSK_KEX2_1	687	689	PF00082	0.487
CLV_PCSK_KEX2_1	738	740	PF00082	0.337
CLV_PCSK_KEX2_1	796	798	PF00082	0.348
CLV_PCSK_PC1ET2_1	1100	1102	PF00082	0.590
CLV_PCSK_PC1ET2_1	1107	1109	PF00082	0.601
CLV_PCSK_PC1ET2_1	306	308	PF00082	0.425
CLV_PCSK_PC1ET2_1	382	384	PF00082	0.382
CLV_PCSK_PC1ET2_1	537	539	PF00082	0.326
CLV_PCSK_PC1ET2_1	548	550	PF00082	0.326
CLV_PCSK_PC7_1	1096	1102	PF00082	0.579
CLV_PCSK_SKI1_1	1018	1022	PF00082	0.326
CLV_PCSK_SKI1_1	1028	1032	PF00082	0.434
CLV_PCSK_SKI1_1	112	116	PF00082	0.420
CLV_PCSK_SKI1_1	191	195	PF00082	0.326
CLV_PCSK_SKI1_1	267	271	PF00082	0.425
CLV_PCSK_SKI1_1	303	307	PF00082	0.406
CLV_PCSK_SKI1_1	316	320	PF00082	0.353
CLV_PCSK_SKI1_1	666	670	PF00082	0.377
CLV_PCSK_SKI1_1	964	968	PF00082	0.393
DEG_APCC_DBOX_1	1027	1035	PF00400	0.671
DOC_ANK_TNKS_1	40	47	PF00023	0.766
DOC_CYCLIN_RxL_1	546	555	PF00134	0.591
DOC_CYCLIN_yCln2_LP_2	691	697	PF00134	0.715
DOC_CYCLIN_yCln2_LP_2	976	982	PF00134	0.383
DOC_MAPK_DCC_7	202	210	PF00069	0.625
DOC_MAPK_gen_1	1028	1034	PF00069	0.673
DOC_MAPK_gen_1	1096	1104	PF00069	0.744
DOC_MAPK_gen_1	321	329	PF00069	0.569
DOC_MAPK_gen_1	392	399	PF00069	0.576
DOC_MAPK_gen_1	422	428	PF00069	0.584
DOC_MAPK_gen_1	546	553	PF00069	0.589
DOC_MAPK_gen_1	803	809	PF00069	0.537
DOC_MAPK_gen_1	81	89	PF00069	0.661
DOC_MAPK_MEF2A_6	139	148	PF00069	0.483
DOC_MAPK_MEF2A_6	202	210	PF00069	0.551
DOC_MAPK_MEF2A_6	392	399	PF00069	0.675
DOC_MAPK_MEF2A_6	633	640	PF00069	0.690
DOC_PP1_RVXF_1	1019	1026	PF00149	0.670
DOC_PP1_RVXF_1	598	605	PF00149	0.601
DOC_PP1_RVXF_1	631	638	PF00149	0.652
DOC_PP2B_LxvP_1	866	869	PF13499	0.537
DOC_PP2B_LxvP_1	976	979	PF13499	0.427
DOC_PP2B_PxIxI_1	753	759	PF00149	0.551
DOC_PP4_FxxP_1	1090	1093	PF00568	0.833
DOC_PP4_FxxP_1	614	617	PF00568	0.612
DOC_USP7_MATH_1	183	187	PF00917	0.623
DOC_USP7_MATH_1	477	481	PF00917	0.551
DOC_USP7_MATH_1	764	768	PF00917	0.526
DOC_USP7_MATH_1	951	955	PF00917	0.593
DOC_USP7_UBL2_3	312	316	PF12436	0.625
DOC_USP7_UBL2_3	418	422	PF12436	0.593
DOC_WW_Pin1_4	347	352	PF00397	0.425
DOC_WW_Pin1_4	71	76	PF00397	0.731
DOC_WW_Pin1_4	722	727	PF00397	0.601
DOC_WW_Pin1_4	750	755	PF00397	0.537
DOC_WW_Pin1_4	834	839	PF00397	0.367
LIG_14-3-3_CanoR_1	1072	1076	PF00244	0.685
LIG_14-3-3_CanoR_1	185	191	PF00244	0.677
LIG_14-3-3_CanoR_1	796	805	PF00244	0.561
LIG_14-3-3_CanoR_1	860	868	PF00244	0.565
LIG_14-3-3_CanoR_1	930	938	PF00244	0.341
LIG_Actin_WH2_2	1059	1074	PF00022	0.681
LIG_Actin_WH2_2	587	602	PF00022	0.595
LIG_BIR_II_1	1	5	PF00653	0.695
LIG_BRCT_BRCA1_1	152	156	PF00533	0.416
LIG_BRCT_BRCA1_1	930	934	PF00533	0.397
LIG_Clathr_ClatBox_1	1031	1035	PF01394	0.731
LIG_Clathr_ClatBox_1	95	99	PF01394	0.551
LIG_CtBP_PxDLS_1	457	461	PF00389	0.641
LIG_deltaCOP1_diTrp_1	158	162	PF00928	0.410
LIG_deltaCOP1_diTrp_1	840	847	PF00928	0.402
LIG_deltaCOP1_diTrp_1	924	934	PF00928	0.338
LIG_deltaCOP1_diTrp_1	962	967	PF00928	0.526
LIG_eIF4E_1	325	331	PF01652	0.551
LIG_FAT_LD_1	323	331	PF03623	0.537
LIG_FHA_1	1014	1020	PF00498	0.549
LIG_FHA_1	141	147	PF00498	0.383
LIG_FHA_1	192	198	PF00498	0.601
LIG_FHA_1	376	382	PF00498	0.530
LIG_FHA_1	409	415	PF00498	0.593
LIG_FHA_1	479	485	PF00498	0.560
LIG_FHA_1	49	55	PF00498	0.775
LIG_FHA_1	565	571	PF00498	0.581
LIG_FHA_1	770	776	PF00498	0.526
LIG_FHA_1	860	866	PF00498	0.564
LIG_FHA_1	875	881	PF00498	0.473
LIG_FHA_2	1054	1060	PF00498	0.789
LIG_FHA_2	411	417	PF00498	0.608
LIG_FHA_2	439	445	PF00498	0.687
LIG_FHA_2	539	545	PF00498	0.633
LIG_FHA_2	578	584	PF00498	0.620
LIG_GBD_Chelix_1	293	301	PF00786	0.393
LIG_Integrin_isoDGR_2	39	41	PF01839	0.575
LIG_IRF3_LxIS_1	820	827	PF10401	0.565
LIG_LIR_Apic_2	1087	1093	PF02991	0.830
LIG_LIR_Apic_2	611	617	PF02991	0.665
LIG_LIR_Gen_1	1009	1017	PF02991	0.455
LIG_LIR_Gen_1	1049	1058	PF02991	0.774
LIG_LIR_Gen_1	1074	1083	PF02991	0.747
LIG_LIR_Gen_1	129	138	PF02991	0.614
LIG_LIR_Gen_1	158	167	PF02991	0.336
LIG_LIR_Gen_1	521	532	PF02991	0.539
LIG_LIR_Gen_1	702	711	PF02991	0.635
LIG_LIR_Gen_1	712	721	PF02991	0.591
LIG_LIR_Gen_1	782	793	PF02991	0.526
LIG_LIR_Gen_1	840	851	PF02991	0.383
LIG_LIR_Gen_1	90	101	PF02991	0.593
LIG_LIR_Nem_3	1009	1013	PF02991	0.383
LIG_LIR_Nem_3	1015	1020	PF02991	0.383
LIG_LIR_Nem_3	1049	1053	PF02991	0.676
LIG_LIR_Nem_3	1074	1078	PF02991	0.717
LIG_LIR_Nem_3	129	133	PF02991	0.620
LIG_LIR_Nem_3	158	162	PF02991	0.408
LIG_LIR_Nem_3	324	328	PF02991	0.554
LIG_LIR_Nem_3	521	527	PF02991	0.540
LIG_LIR_Nem_3	634	640	PF02991	0.576
LIG_LIR_Nem_3	702	706	PF02991	0.633
LIG_LIR_Nem_3	712	717	PF02991	0.610
LIG_LIR_Nem_3	782	788	PF02991	0.526
LIG_LIR_Nem_3	82	87	PF02991	0.624
LIG_LIR_Nem_3	872	878	PF02991	0.576
LIG_LIR_Nem_3	90	96	PF02991	0.558
LIG_LIR_Nem_3	931	937	PF02991	0.371
LIG_LIR_Nem_3	997	1003	PF02991	0.337
LIG_MYND_3	394	398	PF01753	0.671
LIG_Pex14_1	843	847	PF04695	0.383
LIG_Pex14_2	167	171	PF04695	0.367
LIG_Pex14_2	956	960	PF04695	0.529
LIG_PTB_Apo_2	1019	1026	PF02174	0.599
LIG_RPA_C_Fungi	925	937	PF08784	0.402
LIG_SH2_CRK	1017	1021	PF00017	0.383
LIG_SH2_CRK	470	474	PF00017	0.374
LIG_SH2_CRK	644	648	PF00017	0.468
LIG_SH2_GRB2like	982	985	PF00017	0.506
LIG_SH2_NCK_1	349	353	PF00017	0.467
LIG_SH2_SRC	644	647	PF00017	0.466
LIG_SH2_SRC	982	985	PF00017	0.402
LIG_SH2_STAP1	356	360	PF00017	0.367
LIG_SH2_STAT3	468	471	PF00017	0.462
LIG_SH2_STAT5	328	331	PF00017	0.385
LIG_SH2_STAT5	349	352	PF00017	0.506
LIG_SH2_STAT5	468	471	PF00017	0.546
LIG_SH2_STAT5	552	555	PF00017	0.387
LIG_SH2_STAT5	938	941	PF00017	0.367
LIG_SH2_STAT5	946	949	PF00017	0.367
LIG_SH2_STAT5	982	985	PF00017	0.367
LIG_SH3_3	643	649	PF00018	0.474
LIG_SH3_3	945	951	PF00018	0.402
LIG_Sin3_3	50	57	PF02671	0.593
LIG_SUMO_SIM_anti_2	129	136	PF11976	0.461
LIG_SUMO_SIM_anti_2	143	149	PF11976	0.327
LIG_SUMO_SIM_anti_2	218	223	PF11976	0.395
LIG_SUMO_SIM_anti_2	816	822	PF11976	0.368
LIG_SUMO_SIM_anti_2	837	843	PF11976	0.383
LIG_SUMO_SIM_anti_2	877	884	PF11976	0.490
LIG_SUMO_SIM_par_1	1030	1038	PF11976	0.627
LIG_SUMO_SIM_par_1	129	136	PF11976	0.449
LIG_SUMO_SIM_par_1	147	153	PF11976	0.264
LIG_SUMO_SIM_par_1	218	223	PF11976	0.383
LIG_SUMO_SIM_par_1	560	567	PF11976	0.402
LIG_SUMO_SIM_par_1	575	580	PF11976	0.339
LIG_TRAF2_1	617	620	PF00917	0.596
LIG_TRFH_1	834	838	PF08558	0.367
LIG_TYR_ITIM	936	941	PF00017	0.367
LIG_UBA3_1	1023	1029	PF00899	0.654
LIG_UBA3_1	732	741	PF00899	0.383
LIG_WRC_WIRS_1	1007	1012	PF05994	0.421
LIG_WRC_WIRS_1	1050	1055	PF05994	0.700
LIG_WW_3	645	649	PF00397	0.468
MOD_CDK_SPxxK_3	722	729	PF00069	0.462
MOD_CDK_SPxxK_3	750	757	PF00069	0.383
MOD_CK1_1	1074	1080	PF00069	0.595
MOD_CK1_1	1081	1087	PF00069	0.634
MOD_CK1_1	186	192	PF00069	0.517
MOD_CK1_1	311	317	PF00069	0.446
MOD_CK1_1	355	361	PF00069	0.405
MOD_CK1_1	408	414	PF00069	0.449
MOD_CK1_1	531	537	PF00069	0.421
MOD_CK1_1	651	657	PF00069	0.473
MOD_CK1_1	678	684	PF00069	0.540
MOD_CK1_1	725	731	PF00069	0.461
MOD_CK1_1	994	1000	PF00069	0.421
MOD_CK2_1	410	416	PF00069	0.478
MOD_CK2_1	538	544	PF00069	0.517
MOD_CK2_1	834	840	PF00069	0.383
MOD_CK2_1	905	911	PF00069	0.421
MOD_Cter_Amidation	794	797	PF01082	0.399
MOD_GlcNHglycan	12	15	PF01048	0.709
MOD_GlcNHglycan	152	155	PF01048	0.383
MOD_GlcNHglycan	313	316	PF01048	0.418
MOD_GlcNHglycan	33	36	PF01048	0.845
MOD_GlcNHglycan	766	769	PF01048	0.378
MOD_GlcNHglycan	848	851	PF01048	0.402
MOD_GlcNHglycan	907	910	PF01048	0.456
MOD_GSK3_1	1049	1056	PF00069	0.667
MOD_GSK3_1	1074	1081	PF00069	0.609
MOD_GSK3_1	3	10	PF00069	0.824
MOD_GSK3_1	371	378	PF00069	0.372
MOD_GSK3_1	401	408	PF00069	0.422
MOD_GSK3_1	564	571	PF00069	0.423
MOD_GSK3_1	666	673	PF00069	0.561
MOD_GSK3_1	925	932	PF00069	0.546
MOD_N-GLC_1	308	313	PF02516	0.391
MOD_N-GLC_1	401	406	PF02516	0.424
MOD_N-GLC_1	750	755	PF02516	0.367
MOD_NEK2_1	1053	1058	PF00069	0.679
MOD_NEK2_1	1071	1076	PF00069	0.572
MOD_NEK2_1	1078	1083	PF00069	0.585
MOD_NEK2_1	308	313	PF00069	0.563
MOD_NEK2_1	377	382	PF00069	0.375
MOD_NEK2_1	478	483	PF00069	0.382
MOD_NEK2_1	732	737	PF00069	0.500
MOD_NEK2_1	809	814	PF00069	0.383
MOD_NEK2_1	846	851	PF00069	0.383
MOD_NEK2_1	942	947	PF00069	0.427
MOD_NEK2_1	991	996	PF00069	0.421
MOD_NEK2_2	829	834	PF00069	0.548
MOD_NEK2_2	951	956	PF00069	0.460
MOD_PIKK_1	133	139	PF00454	0.515
MOD_PIKK_1	278	284	PF00454	0.393
MOD_PIKK_1	577	583	PF00454	0.631
MOD_PIKK_1	796	802	PF00454	0.421
MOD_PIKK_1	869	875	PF00454	0.421
MOD_PKA_1	537	543	PF00069	0.367
MOD_PKA_1	7	13	PF00069	0.626
MOD_PKA_1	796	802	PF00069	0.421
MOD_PKA_2	1071	1077	PF00069	0.589
MOD_PKA_2	278	284	PF00069	0.367
MOD_PKA_2	537	543	PF00069	0.367
MOD_PKA_2	651	657	PF00069	0.566
MOD_PKA_2	796	802	PF00069	0.444
MOD_PKA_2	859	865	PF00069	0.421
MOD_PKA_2	929	935	PF00069	0.364
MOD_PKA_2	951	957	PF00069	0.371
MOD_Plk_1	183	189	PF00069	0.491
MOD_Plk_1	528	534	PF00069	0.528
MOD_Plk_2-3	707	713	PF00069	0.545
MOD_Plk_2-3	859	865	PF00069	0.506
MOD_Plk_4	1006	1012	PF00069	0.296
MOD_Plk_4	126	132	PF00069	0.507
MOD_Plk_4	479	485	PF00069	0.408
MOD_Plk_4	651	657	PF00069	0.512
MOD_Plk_4	678	684	PF00069	0.540
MOD_Plk_4	784	790	PF00069	0.367
MOD_Plk_4	829	835	PF00069	0.499
MOD_Plk_4	881	887	PF00069	0.400
MOD_Plk_4	951	957	PF00069	0.367
MOD_Plk_4	991	997	PF00069	0.562
MOD_ProDKin_1	347	353	PF00069	0.506
MOD_ProDKin_1	71	77	PF00069	0.647
MOD_ProDKin_1	722	728	PF00069	0.466
MOD_ProDKin_1	750	756	PF00069	0.383
MOD_ProDKin_1	834	840	PF00069	0.367
MOD_SUMO_for_1	547	550	PF00179	0.421
MOD_SUMO_rev_2	529	536	PF00179	0.383
MOD_SUMO_rev_2	540	547	PF00179	0.383
MOD_SUMO_rev_2	571	577	PF00179	0.642
MOD_SUMO_rev_2	725	730	PF00179	0.463
TRG_DiLeu_BaEn_1	572	577	PF01217	0.627
TRG_DiLeu_BaEn_1	816	821	PF01217	0.367
TRG_ENDOCYTIC_2	1017	1020	PF00928	0.383
TRG_ENDOCYTIC_2	1050	1053	PF00928	0.571
TRG_ENDOCYTIC_2	328	331	PF00928	0.383
TRG_ENDOCYTIC_2	470	473	PF00928	0.453
TRG_ENDOCYTIC_2	938	941	PF00928	0.367
TRG_ER_diArg_1	1105	1108	PF00400	0.808
TRG_ER_diArg_1	686	689	PF00400	0.576
TRG_ER_diArg_1	796	798	PF00400	0.398
TRG_ER_diArg_1	956	959	PF00400	0.467
TRG_NES_CRM1_1	207	218	PF08389	0.460
TRG_NES_CRM1_1	634	645	PF08389	0.435
TRG_NLS_MonoCore_2	1097	1102	PF00514	0.686
TRG_NLS_MonoExtN_4	1096	1103	PF00514	0.716
TRG_NLS_MonoExtN_4	738	743	PF00514	0.427
TRG_Pf-PMV_PEXEL_1	1029	1033	PF00026	0.656
TRG_Pf-PMV_PEXEL_1	19	23	PF00026	0.716
TRG_Pf-PMV_PEXEL_1	41	45	PF00026	0.706
TRG_Pf-PMV_PEXEL_1	467	471	PF00026	0.454
TRG_Pf-PMV_PEXEL_1	592	597	PF00026	0.584
TRG_Pf-PMV_PEXEL_1	666	671	PF00026	0.447
TRG_Pf-PMV_PEXEL_1	689	693	PF00026	0.626
TRG_Pf-PMV_PEXEL_1	796	800	PF00026	0.425

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Y1	Leptomonas seymouri	30%	100%
A0A0N1HWG6	Leptomonas seymouri	28%	99%
A0A0N1PFH3	Leptomonas seymouri	83%	91%
A0A0S4IM76	Bodo saltans	23%	100%
A0A0S4J1M1	Bodo saltans	29%	100%
A0A0S4J5A1	Bodo saltans	50%	100%
A0A0S4JA92	Bodo saltans	27%	100%
A0A0S4JRV4	Bodo saltans	30%	100%
A0A0S4JT33	Bodo saltans	22%	100%
A0A0S4KIG5	Bodo saltans	31%	100%
A0A0S4KNQ6	Bodo saltans	27%	99%
A0A1X0NNY6	Trypanosomatidae	30%	100%
A0A1X0NPD9	Trypanosomatidae	27%	100%
A0A1X0NTI6	Trypanosomatidae	28%	98%
A0A1X0P689	Trypanosomatidae	69%	100%
A0A1X0P720	Trypanosomatidae	25%	100%
A0A1X0P724	Trypanosomatidae	25%	100%
A0A381MFJ0	Leishmania infantum	27%	100%
A0A3R7MRX8	Trypanosoma rangeli	63%	100%
A0A3S5H5Y9	Leishmania donovani	27%	100%
A0A3S5ISK9	Trypanosoma rangeli	26%	100%
A0A3S7WPW0	Leishmania donovani	25%	100%
A0A3S7WV61	Leishmania donovani	26%	100%
A0A3S7WV68	Leishmania donovani	27%	100%
A0A422NTS7	Trypanosoma rangeli	30%	100%
A0A451EJU6	Leishmania donovani	31%	100%
A2VDL6	Bos taurus	29%	100%
A4H3S2	Leishmania braziliensis	31%	100%
A4H514	Leishmania braziliensis	26%	100%
A4H903	Leishmania braziliensis	29%	100%
A4H9Q5	Leishmania braziliensis	27%	100%
A4HMM8	Leishmania braziliensis	90%	100%
A4HRZ6	Leishmania infantum	31%	100%
A4HT82	Leishmania infantum	26%	100%
A4HTF0	Leishmania infantum	27%	100%
A4HY23	Leishmania infantum	27%	100%
A4IBA6	Leishmania infantum	100%	100%
A7L9Z8	Mus musculus	27%	100%
C9ZPL1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
C9ZUN6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
C9ZZN4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	100%
D0A4V8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0A564	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	100%
D2WKD8	Sus scrofa	29%	100%
E9AF31	Leishmania major	97%	100%
E9AJY3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AL76	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AL78	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9AR29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9ART6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B686	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
F1Q4S1	Danio rerio	24%	99%
J9VQQ3	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	26%	78%
O14983	Homo sapiens	30%	100%
O22218	Arabidopsis thaliana	28%	100%
O23087	Arabidopsis thaliana	31%	100%
O34431	Bacillus subtilis (strain 168)	34%	100%
O43108	Yarrowia lipolytica (strain CLIB 122 / E 150)	29%	100%
O46674	Canis lupus familiaris	30%	100%
O55143	Mus musculus	30%	100%
O59868	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	100%
O70228	Mus musculus	22%	100%
O75110	Homo sapiens	22%	100%
O77696	Sus scrofa	31%	100%
O81108	Arabidopsis thaliana	29%	100%
P04074	Ovis aries	30%	100%
P04191	Oryctolagus cuniculus	30%	100%
P05023	Homo sapiens	30%	100%
P05024	Sus scrofa	30%	100%
P05025	Tetronarce californica	29%	100%
P06685	Rattus norvegicus	31%	100%
P06686	Rattus norvegicus	29%	100%
P06687	Rattus norvegicus	31%	100%
P09572	Gallus gallus	30%	100%
P09626	Rattus norvegicus	29%	100%
P0ABB8	Escherichia coli (strain K12)	26%	100%
P0ABB9	Escherichia coli O157:H7	26%	100%
P11507	Rattus norvegicus	30%	100%
P11607	Sus scrofa	30%	100%
P12522	Leishmania donovani	27%	100%
P13585	Gallus gallus	31%	100%
P13586	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P13587	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
P13607	Drosophila melanogaster	28%	100%
P13637	Homo sapiens	31%	100%
P16615	Homo sapiens	30%	100%
P17326	Artemia franciscana	28%	100%
P18596	Rattus norvegicus	31%	100%
P18907	Equus caballus	30%	100%
P19156	Sus scrofa	29%	100%
P20647	Oryctolagus cuniculus	30%	100%
P20648	Homo sapiens	30%	100%
P22036	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	24%	100%
P22189	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	37%	100%
P22700	Drosophila melanogaster	31%	100%
P23634	Homo sapiens	28%	89%
P24797	Gallus gallus	29%	100%
P24798	Gallus gallus	31%	100%
P25489	Catostomus commersonii	29%	100%
P27112	Oryctolagus cuniculus	29%	100%
P28774	Artemia franciscana	29%	100%
P30714	Rhinella marina	30%	100%
P35315	Trypanosoma brucei brucei	30%	100%
P35316	Artemia franciscana	29%	100%
P35317	Hydra vulgaris	30%	100%
P37278	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	34%	100%
P37367	Synechocystis sp. (strain PCC 6803 / Kazusa)	35%	100%
P47317	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	30%	100%
P50993	Homo sapiens	29%	100%
P50996	Canis lupus familiaris	29%	100%
P50997	Canis lupus familiaris	30%	100%
P54209	Dunaliella bioculata	31%	100%
P54210	Dunaliella acidophila	24%	100%
P54211	Dunaliella bioculata	25%	98%
P54678	Dictyostelium discoideum	29%	99%
P54679	Dictyostelium discoideum	25%	100%
P54707	Homo sapiens	28%	100%
P54708	Rattus norvegicus	29%	100%
P57709	Bos taurus	30%	100%
P58312	Oreochromis mossambicus	29%	100%
P63688	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	30%	100%
P70083	Makaira nigricans	30%	100%
P70704	Mus musculus	22%	95%
P78036	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	30%	100%
P92939	Arabidopsis thaliana	31%	100%
P98194	Homo sapiens	30%	100%
P98195	Mus musculus	23%	97%
P9WPS8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	30%	100%
P9WPS9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	30%	100%
Q00779	Felis catus	30%	100%
Q01896	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	100%
Q03669	Gallus gallus	29%	100%
Q08436	Nicotiana plumbaginifolia	24%	100%
Q08DA1	Bos taurus	30%	100%
Q0VCY0	Bos taurus	30%	100%
Q12691	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	100%
Q292Q0	Drosophila pseudoobscura pseudoobscura	30%	100%
Q29449	Bos taurus	22%	97%
Q2QY12	Oryza sativa subsp. japonica	26%	100%
Q2RAS0	Oryza sativa subsp. japonica	26%	100%
Q42556	Arabidopsis thaliana	25%	100%
Q42883	Solanum lycopersicum	32%	100%
Q4QDN7	Leishmania major	26%	100%
Q4QDN8	Leishmania major	26%	100%
Q4QED4	Leishmania major	28%	100%
Q4QIM6	Leishmania major	27%	100%
Q4QIM8	Leishmania major	27%	100%
Q58623	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	29%	100%
Q5R5K5	Pongo abelii	30%	100%
Q5RCD8	Pongo abelii	29%	100%
Q5RDR3	Pongo abelii	31%	100%
Q64392	Cavia porcellus	29%	100%
Q64518	Mus musculus	32%	100%
Q64541	Rattus norvegicus	28%	100%
Q64542	Rattus norvegicus	27%	92%
Q64566	Rattus norvegicus	30%	100%
Q64578	Rattus norvegicus	29%	100%
Q65X71	Oryza sativa subsp. japonica	27%	100%
Q6ATV4	Oryza sativa subsp. japonica	30%	100%
Q6DFW5	Mus musculus	24%	94%
Q6PIC6	Mus musculus	31%	100%
Q6PIE5	Mus musculus	29%	100%
Q6RWA9	Taenia solium	29%	100%
Q73E41	Bacillus cereus (strain ATCC 10987 / NRS 248)	34%	100%
Q7PPA5	Anopheles gambiae	30%	100%
Q7X8B5	Oryza sativa subsp. japonica	27%	100%
Q7XEK4	Oryza sativa subsp. japonica	28%	100%
Q80XR2	Mus musculus	30%	100%
Q8R429	Mus musculus	29%	100%
Q8R4C1	Rattus norvegicus	29%	100%
Q8VDN2	Mus musculus	31%	100%
Q8Y8Q5	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	30%	100%
Q92030	Anguilla anguilla	29%	100%
Q92036	Rhinella marina	29%	100%
Q92105	Pelophylax lessonae	30%	100%
Q92123	Xenopus laevis	30%	100%
Q92126	Xenopus laevis	28%	100%
Q93084	Homo sapiens	31%	100%
Q95Z93	Leishmania major	31%	100%
Q9CFU9	Lactococcus lactis subsp. lactis (strain IL1403)	29%	100%
Q9CTG6	Mus musculus	21%	95%
Q9H7F0	Homo sapiens	22%	90%
Q9HDW7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	86%
Q9LF79	Arabidopsis thaliana	30%	100%
Q9LIK7	Arabidopsis thaliana	27%	100%
Q9LU41	Arabidopsis thaliana	29%	100%
Q9LY77	Arabidopsis thaliana	27%	100%
Q9M2A0	Arabidopsis thaliana	24%	100%
Q9M2L4	Arabidopsis thaliana	28%	100%
Q9N0Z6	Oryctolagus cuniculus	30%	100%
Q9R0K7	Mus musculus	29%	93%
Q9SY55	Arabidopsis thaliana	31%	100%
Q9SZR1	Arabidopsis thaliana	29%	100%
Q9TV52	Oryctolagus cuniculus	29%	100%
Q9WV27	Mus musculus	28%	100%
Q9XES1	Arabidopsis thaliana	32%	100%
Q9YGL9	Gallus gallus	31%	100%
Q9YH26	Oreochromis mossambicus	29%	100%
Q9Z1W8	Mus musculus	29%	100%
V5B873	Trypanosoma cruzi	25%	100%
V5BHZ2	Trypanosoma cruzi	67%	100%
V5BLM1	Trypanosoma cruzi	31%	100%