Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X929_LEIDO

TriTrypDb:

LdBPK_351640.1 , LdCL_350021300 , LDHU3_35.2180

Length:

356

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X929

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X929

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	135	137	PF00675	0.720
CLV_NRD_NRD_1	228	230	PF00675	0.592
CLV_NRD_NRD_1	253	255	PF00675	0.593
CLV_PCSK_KEX2_1	228	230	PF00082	0.592
CLV_PCSK_KEX2_1	253	255	PF00082	0.585
CLV_PCSK_SKI1_1	244	248	PF00082	0.642
CLV_PCSK_SKI1_1	276	280	PF00082	0.580
CLV_PCSK_SKI1_1	72	76	PF00082	0.616
DEG_SCF_TRCP1_1	25	31	PF00400	0.578
DOC_MIT_MIM_1	347	356	PF04212	0.609
DOC_PP4_FxxP_1	144	147	PF00568	0.675
DOC_USP7_MATH_1	189	193	PF00917	0.696
DOC_USP7_MATH_1	218	222	PF00917	0.702
DOC_USP7_MATH_1	311	315	PF00917	0.632
DOC_USP7_MATH_1	327	331	PF00917	0.696
DOC_USP7_MATH_1	50	54	PF00917	0.575
DOC_WW_Pin1_4	157	162	PF00397	0.758
DOC_WW_Pin1_4	75	80	PF00397	0.647
DOC_WW_Pin1_4	88	93	PF00397	0.711
LIG_14-3-3_CanoR_1	320	328	PF00244	0.558
LIG_14-3-3_CanoR_1	95	104	PF00244	0.761
LIG_Actin_WH2_2	293	309	PF00022	0.700
LIG_APCC_ABBA_1	265	270	PF00400	0.566
LIG_EH1_1	240	248	PF00400	0.637
LIG_FHA_1	55	61	PF00498	0.709
LIG_LIR_Apic_2	142	147	PF02991	0.679
LIG_LIR_Gen_1	28	38	PF02991	0.580
LIG_LIR_Nem_3	263	269	PF02991	0.584
LIG_LIR_Nem_3	280	285	PF02991	0.636
LIG_LYPXL_S_1	265	269	PF13949	0.458
LIG_MAD2	4	12	PF02301	0.694
LIG_NRBOX	212	218	PF00104	0.694
LIG_PDZ_Class_3	351	356	PF00595	0.692
LIG_Pex14_2	265	269	PF04695	0.671
LIG_SH2_STAP1	30	34	PF00017	0.583
LIG_SH2_STAT3	283	286	PF00017	0.712
LIG_SH2_STAT5	166	169	PF00017	0.558
LIG_SH3_3	13	19	PF00018	0.673
LIG_SH3_3	3	9	PF00018	0.674
LIG_TRAF2_1	129	132	PF00917	0.781
LIG_WW_1	146	149	PF00397	0.781
MOD_CDK_SPxxK_3	75	82	PF00069	0.682
MOD_CDK_SPxxK_3	88	95	PF00069	0.572
MOD_CK1_1	152	158	PF00069	0.661
MOD_CK1_1	160	166	PF00069	0.686
MOD_CK1_1	28	34	PF00069	0.724
MOD_CK2_1	126	132	PF00069	0.771
MOD_CK2_1	189	195	PF00069	0.657
MOD_CK2_1	319	325	PF00069	0.583
MOD_GlcNHglycan	128	131	PF01048	0.756
MOD_GlcNHglycan	152	155	PF01048	0.608
MOD_GlcNHglycan	192	195	PF01048	0.708
MOD_GlcNHglycan	24	28	PF01048	0.727
MOD_GlcNHglycan	286	289	PF01048	0.710
MOD_GlcNHglycan	321	324	PF01048	0.576
MOD_GlcNHglycan	52	55	PF01048	0.715
MOD_GlcNHglycan	98	101	PF01048	0.721
MOD_GSK3_1	149	156	PF00069	0.771
MOD_GSK3_1	25	32	PF00069	0.716
MOD_GSK3_1	284	291	PF00069	0.665
MOD_GSK3_1	46	53	PF00069	0.670
MOD_NEK2_1	23	28	PF00069	0.646
MOD_PIKK_1	160	166	PF00454	0.654
MOD_PKA_2	149	155	PF00069	0.788
MOD_PKA_2	319	325	PF00069	0.566
MOD_Plk_4	11	17	PF00069	0.691
MOD_Plk_4	29	35	PF00069	0.690
MOD_Plk_4	327	333	PF00069	0.696
MOD_ProDKin_1	157	163	PF00069	0.753
MOD_ProDKin_1	75	81	PF00069	0.651
MOD_ProDKin_1	88	94	PF00069	0.712
MOD_SUMO_rev_2	99	108	PF00179	0.598
TRG_DiLeu_BaEn_1	177	182	PF01217	0.719
TRG_DiLeu_BaLyEn_6	212	217	PF01217	0.485
TRG_ENDOCYTIC_2	266	269	PF00928	0.499
TRG_ENDOCYTIC_2	282	285	PF00928	0.613
TRG_ENDOCYTIC_2	30	33	PF00928	0.579
TRG_ER_diArg_1	241	244	PF00400	0.514
TRG_ER_diArg_1	349	352	PF00400	0.489
TRG_Pf-PMV_PEXEL_1	215	219	PF00026	0.481

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKF7	Leptomonas seymouri	37%	100%
A4HMI5	Leishmania braziliensis	72%	100%
A4IB65	Leishmania infantum	99%	100%
E9AEY6	Leishmania major	90%	100%
E9B642	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%