Chromo domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X907_LEIDO

TriTrypDb:

LdBPK_351300.1 , LdCL_350017900 , LDHU3_35.1720

Length:

249

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X907

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X907

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	199	203	PF00656	0.467
CLV_NRD_NRD_1	118	120	PF00675	0.728
CLV_NRD_NRD_1	195	197	PF00675	0.554
CLV_NRD_NRD_1	247	249	PF00675	0.615
CLV_NRD_NRD_1	99	101	PF00675	0.461
CLV_PCSK_KEX2_1	118	120	PF00082	0.728
CLV_PCSK_KEX2_1	195	197	PF00082	0.522
CLV_PCSK_KEX2_1	213	215	PF00082	0.399
CLV_PCSK_KEX2_1	246	248	PF00082	0.638
CLV_PCSK_PC1ET2_1	118	120	PF00082	0.728
CLV_PCSK_PC1ET2_1	213	215	PF00082	0.560
CLV_PCSK_PC7_1	209	215	PF00082	0.538
CLV_PCSK_PC7_1	243	249	PF00082	0.674
CLV_PCSK_SKI1_1	18	22	PF00082	0.558
DEG_SCF_TRCP1_1	232	238	PF00400	0.638
DOC_CYCLIN_RxL_1	154	167	PF00134	0.573
DOC_PP2B_PxIxI_1	12	18	PF00149	0.481
DOC_USP7_MATH_1	141	145	PF00917	0.715
DOC_USP7_MATH_1	67	71	PF00917	0.744
DOC_WW_Pin1_4	1	6	PF00397	0.721
DOC_WW_Pin1_4	48	53	PF00397	0.620
DOC_WW_Pin1_4	73	78	PF00397	0.742
DOC_WW_Pin1_4	79	84	PF00397	0.637
LIG_14-3-3_CanoR_1	140	148	PF00244	0.743
LIG_14-3-3_CanoR_1	18	23	PF00244	0.536
LIG_14-3-3_CanoR_1	37	41	PF00244	0.253
LIG_14-3-3_CterR_2	246	249	PF00244	0.687
LIG_Actin_WH2_2	185	203	PF00022	0.605
LIG_FHA_1	12	18	PF00498	0.419
LIG_FHA_1	158	164	PF00498	0.549
LIG_FHA_1	37	43	PF00498	0.489
LIG_FHA_2	110	116	PF00498	0.596
LIG_FHA_2	55	61	PF00498	0.729
LIG_LIR_Apic_2	107	111	PF02991	0.530
LIG_MYND_1	83	87	PF01753	0.614
LIG_Pex14_2	104	108	PF04695	0.451
LIG_PTB_Apo_2	27	34	PF02174	0.539
LIG_REV1ctd_RIR_1	31	41	PF16727	0.557
LIG_SH2_STAT5	103	106	PF00017	0.358
LIG_SH2_STAT5	95	98	PF00017	0.421
LIG_SH3_1	84	90	PF00018	0.601
LIG_SH3_3	80	86	PF00018	0.520
LIG_TRAF2_1	112	115	PF00917	0.610
MOD_CDK_SPK_2	79	84	PF00069	0.651
MOD_CK1_1	123	129	PF00069	0.671
MOD_CK1_1	54	60	PF00069	0.775
MOD_CK2_1	109	115	PF00069	0.549
MOD_CK2_1	21	27	PF00069	0.434
MOD_CK2_1	54	60	PF00069	0.727
MOD_CK2_1	62	68	PF00069	0.753
MOD_Cter_Amidation	116	119	PF01082	0.520
MOD_GlcNHglycan	126	129	PF01048	0.751
MOD_GlcNHglycan	182	185	PF01048	0.535
MOD_GlcNHglycan	218	223	PF01048	0.583
MOD_GlcNHglycan	232	235	PF01048	0.641
MOD_GlcNHglycan	237	240	PF01048	0.564
MOD_GlcNHglycan	5	8	PF01048	0.639
MOD_GlcNHglycan	53	56	PF01048	0.668
MOD_GlcNHglycan	65	68	PF01048	0.787
MOD_GlcNHglycan	69	72	PF01048	0.763
MOD_GSK3_1	120	127	PF00069	0.704
MOD_GSK3_1	218	225	PF00069	0.606
MOD_GSK3_1	3	10	PF00069	0.672
MOD_GSK3_1	63	70	PF00069	0.797
MOD_PIKK_1	141	147	PF00454	0.740
MOD_PKA_2	146	152	PF00069	0.525
MOD_PKA_2	208	214	PF00069	0.520
MOD_PKA_2	230	236	PF00069	0.646
MOD_PKA_2	36	42	PF00069	0.481
MOD_PKA_2	96	102	PF00069	0.545
MOD_Plk_1	157	163	PF00069	0.537
MOD_Plk_4	11	17	PF00069	0.417
MOD_Plk_4	187	193	PF00069	0.610
MOD_ProDKin_1	1	7	PF00069	0.719
MOD_ProDKin_1	48	54	PF00069	0.622
MOD_ProDKin_1	73	79	PF00069	0.741
MOD_SUMO_rev_2	60	65	PF00179	0.613
TRG_ENDOCYTIC_2	103	106	PF00928	0.380
TRG_ER_diArg_1	245	248	PF00400	0.603
TRG_Pf-PMV_PEXEL_1	154	158	PF00026	0.487

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5V4	Leptomonas seymouri	51%	100%
A0A1X0NIU6	Trypanosomatidae	31%	100%
A0A3R7JUY0	Trypanosoma rangeli	31%	100%
A4HMF1	Leishmania braziliensis	75%	100%
A4IB23	Leishmania infantum	99%	100%
C9ZNL9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	100%
E9B608	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q9GN98	Leishmania major	93%	100%