RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

RNA helicase

Gene product:

pre-mRNA splicing factor ATP-dependent RNA helicase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X8Z5_LEIDO

TriTrypDb:

LdBPK_351210.1 , LdCL_350016900 , LDHU3_35.1610

Length:

704

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X8Z5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8Z5

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006396	RNA processing	6	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0008380	RNA splicing	7	11
GO:0009987	cellular process	1	11
GO:0016070	RNA metabolic process	5	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0043170	macromolecule metabolic process	3	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0046483	heterocycle metabolic process	3	11
GO:0071704	organic substance metabolic process	2	11
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003724	RNA helicase activity	3	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008186	ATP-dependent activity, acting on RNA	2	11
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140098	catalytic activity, acting on RNA	3	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003676	nucleic acid binding	3	9
GO:0003723	RNA binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	289	291	PF00675	0.230
CLV_NRD_NRD_1	300	302	PF00675	0.211
CLV_NRD_NRD_1	557	559	PF00675	0.347
CLV_NRD_NRD_1	572	574	PF00675	0.534
CLV_NRD_NRD_1	590	592	PF00675	0.212
CLV_NRD_NRD_1	630	632	PF00675	0.224
CLV_NRD_NRD_1	685	687	PF00675	0.394
CLV_NRD_NRD_1	693	695	PF00675	0.468
CLV_NRD_NRD_1	82	84	PF00675	0.218
CLV_PCSK_FUR_1	694	698	PF00082	0.571
CLV_PCSK_KEX2_1	170	172	PF00082	0.352
CLV_PCSK_KEX2_1	186	188	PF00082	0.368
CLV_PCSK_KEX2_1	557	559	PF00082	0.336
CLV_PCSK_KEX2_1	572	574	PF00082	0.490
CLV_PCSK_KEX2_1	590	592	PF00082	0.214
CLV_PCSK_KEX2_1	630	632	PF00082	0.224
CLV_PCSK_KEX2_1	685	687	PF00082	0.393
CLV_PCSK_KEX2_1	693	695	PF00082	0.469
CLV_PCSK_KEX2_1	696	698	PF00082	0.503
CLV_PCSK_KEX2_1	82	84	PF00082	0.218
CLV_PCSK_PC1ET2_1	170	172	PF00082	0.445
CLV_PCSK_PC1ET2_1	186	188	PF00082	0.461
CLV_PCSK_PC1ET2_1	696	698	PF00082	0.536
CLV_PCSK_SKI1_1	122	126	PF00082	0.224
CLV_PCSK_SKI1_1	165	169	PF00082	0.354
CLV_PCSK_SKI1_1	19	23	PF00082	0.487
CLV_PCSK_SKI1_1	225	229	PF00082	0.353
CLV_PCSK_SKI1_1	290	294	PF00082	0.224
CLV_PCSK_SKI1_1	540	544	PF00082	0.347
CLV_PCSK_SKI1_1	600	604	PF00082	0.249
CLV_PCSK_SKI1_1	619	623	PF00082	0.223
CLV_PCSK_SKI1_1	649	653	PF00082	0.224
CLV_PCSK_SKI1_1	677	681	PF00082	0.349
CLV_Separin_Metazoa	387	391	PF03568	0.329
DEG_APCC_DBOX_1	170	178	PF00400	0.331
DEG_APCC_DBOX_1	389	397	PF00400	0.323
DEG_Nend_UBRbox_2	1	3	PF02207	0.656
DOC_CKS1_1	343	348	PF01111	0.424
DOC_CKS1_1	486	491	PF01111	0.490
DOC_CYCLIN_RxL_1	554	565	PF00134	0.419
DOC_MAPK_gen_1	170	178	PF00069	0.331
DOC_MAPK_gen_1	25	32	PF00069	0.366
DOC_MAPK_gen_1	336	344	PF00069	0.424
DOC_MAPK_gen_1	540	548	PF00069	0.339
DOC_MAPK_gen_1	557	563	PF00069	0.359
DOC_MAPK_gen_1	630	637	PF00069	0.424
DOC_MAPK_HePTP_8	89	101	PF00069	0.424
DOC_MAPK_MEF2A_6	170	178	PF00069	0.331
DOC_MAPK_MEF2A_6	331	339	PF00069	0.424
DOC_MAPK_MEF2A_6	92	101	PF00069	0.424
DOC_MAPK_RevD_3	172	187	PF00069	0.352
DOC_PP1_RVXF_1	617	624	PF00149	0.424
DOC_PP1_RVXF_1	631	638	PF00149	0.423
DOC_PP1_SILK_1	553	558	PF00149	0.412
DOC_PP2B_LxvP_1	559	562	PF13499	0.446
DOC_PP2B_LxvP_1	603	606	PF13499	0.424
DOC_PP4_FxxP_1	413	416	PF00568	0.350
DOC_PP4_FxxP_1	462	465	PF00568	0.502
DOC_PP4_FxxP_1	486	489	PF00568	0.435
DOC_PP4_FxxP_1	504	507	PF00568	0.435
DOC_USP7_MATH_1	263	267	PF00917	0.443
DOC_USP7_MATH_1	3	7	PF00917	0.645
DOC_USP7_MATH_1	310	314	PF00917	0.424
DOC_USP7_MATH_1	34	38	PF00917	0.477
DOC_USP7_MATH_1	562	566	PF00917	0.454
DOC_USP7_MATH_1	85	89	PF00917	0.435
DOC_USP7_UBL2_3	114	118	PF12436	0.495
DOC_USP7_UBL2_3	615	619	PF12436	0.424
DOC_WW_Pin1_4	342	347	PF00397	0.424
DOC_WW_Pin1_4	461	466	PF00397	0.435
DOC_WW_Pin1_4	485	490	PF00397	0.462
DOC_WW_Pin1_4	660	665	PF00397	0.449
DOC_WW_Pin1_4	697	702	PF00397	0.636
LIG_14-3-3_CanoR_1	153	161	PF00244	0.359
LIG_14-3-3_CanoR_1	19	24	PF00244	0.384
LIG_14-3-3_CanoR_1	225	233	PF00244	0.349
LIG_14-3-3_CanoR_1	369	376	PF00244	0.342
LIG_14-3-3_CanoR_1	557	562	PF00244	0.316
LIG_14-3-3_CanoR_1	649	658	PF00244	0.424
LIG_14-3-3_CanoR_1	83	93	PF00244	0.443
LIG_Actin_WH2_2	117	133	PF00022	0.424
LIG_Actin_WH2_2	160	177	PF00022	0.330
LIG_APCC_ABBA_1	518	523	PF00400	0.366
LIG_APCC_ABBA_1	634	639	PF00400	0.424
LIG_APCC_ABBAyCdc20_2	633	639	PF00400	0.435
LIG_BRCT_BRCA1_1	107	111	PF00533	0.466
LIG_BRCT_BRCA1_1	17	21	PF00533	0.511
LIG_BRCT_BRCA1_1	458	462	PF00533	0.521
LIG_BRCT_BRCA1_1	463	467	PF00533	0.521
LIG_Clathr_ClatBox_1	408	412	PF01394	0.365
LIG_EH_1	483	487	PF12763	0.490
LIG_eIF4E_1	46	52	PF01652	0.266
LIG_FHA_1	133	139	PF00498	0.475
LIG_FHA_1	155	161	PF00498	0.320
LIG_FHA_1	298	304	PF00498	0.424
LIG_FHA_1	46	52	PF00498	0.266
LIG_FHA_1	58	64	PF00498	0.424
LIG_FHA_1	674	680	PF00498	0.490
LIG_FHA_2	10	16	PF00498	0.520
LIG_FHA_2	161	167	PF00498	0.449
LIG_FHA_2	180	186	PF00498	0.244
LIG_FHA_2	242	248	PF00498	0.427
LIG_FHA_2	249	255	PF00498	0.418
LIG_FHA_2	293	299	PF00498	0.502
LIG_FHA_2	382	388	PF00498	0.348
LIG_FHA_2	611	617	PF00498	0.424
LIG_FHA_2	698	704	PF00498	0.689
LIG_LIR_Apic_2	412	416	PF02991	0.354
LIG_LIR_Apic_2	459	465	PF02991	0.502
LIG_LIR_Apic_2	502	507	PF02991	0.507
LIG_LIR_Apic_2	533	539	PF02991	0.366
LIG_LIR_Gen_1	140	150	PF02991	0.521
LIG_LIR_Gen_1	18	28	PF02991	0.402
LIG_LIR_Gen_1	44	52	PF02991	0.403
LIG_LIR_Gen_1	513	522	PF02991	0.443
LIG_LIR_Nem_3	140	145	PF02991	0.521
LIG_LIR_Nem_3	17	23	PF02991	0.372
LIG_LIR_Nem_3	185	191	PF02991	0.367
LIG_LIR_Nem_3	384	388	PF02991	0.386
LIG_LIR_Nem_3	44	49	PF02991	0.480
LIG_LIR_Nem_3	513	517	PF02991	0.395
LIG_LIR_Nem_3	670	675	PF02991	0.384
LIG_LYPXL_yS_3	385	388	PF13949	0.349
LIG_MLH1_MIPbox_1	17	21	PF16413	0.511
LIG_Pex14_2	188	192	PF04695	0.347
LIG_Pex14_2	680	684	PF04695	0.462
LIG_PTB_Apo_2	407	414	PF02174	0.374
LIG_PTB_Apo_2	516	523	PF02174	0.298
LIG_PTB_Phospho_1	516	522	PF10480	0.291
LIG_SH2_CRK	142	146	PF00017	0.424
LIG_SH2_CRK	281	285	PF00017	0.424
LIG_SH2_CRK	46	50	PF00017	0.266
LIG_SH2_CRK	549	553	PF00017	0.324
LIG_SH2_GRB2like	514	517	PF00017	0.438
LIG_SH2_GRB2like	536	539	PF00017	0.330
LIG_SH2_GRB2like	627	630	PF00017	0.521
LIG_SH2_PTP2	536	539	PF00017	0.467
LIG_SH2_SRC	219	222	PF00017	0.333
LIG_SH2_SRC	514	517	PF00017	0.421
LIG_SH2_SRC	536	539	PF00017	0.330
LIG_SH2_STAP1	107	111	PF00017	0.435
LIG_SH2_STAP1	142	146	PF00017	0.424
LIG_SH2_STAP1	16	20	PF00017	0.507
LIG_SH2_STAT3	567	570	PF00017	0.506
LIG_SH2_STAT3	666	669	PF00017	0.473
LIG_SH2_STAT5	123	126	PF00017	0.455
LIG_SH2_STAT5	191	194	PF00017	0.364
LIG_SH2_STAT5	20	23	PF00017	0.390
LIG_SH2_STAT5	219	222	PF00017	0.354
LIG_SH2_STAT5	371	374	PF00017	0.341
LIG_SH2_STAT5	431	434	PF00017	0.408
LIG_SH2_STAT5	514	517	PF00017	0.413
LIG_SH2_STAT5	536	539	PF00017	0.350
LIG_SH2_STAT5	567	570	PF00017	0.506
LIG_SH2_STAT5	597	600	PF00017	0.435
LIG_SH2_STAT5	627	630	PF00017	0.521
LIG_SH2_STAT5	647	650	PF00017	0.317
LIG_SH2_STAT5	66	69	PF00017	0.521
LIG_SH2_STAT5	666	669	PF00017	0.343
LIG_SH3_3	166	172	PF00018	0.359
LIG_SH3_3	329	335	PF00018	0.424
LIG_SH3_3	411	417	PF00018	0.345
LIG_SH3_3	449	455	PF00018	0.424
LIG_SH3_3	479	485	PF00018	0.424
LIG_SUMO_SIM_anti_2	143	149	PF11976	0.424
LIG_SUMO_SIM_anti_2	48	55	PF11976	0.424
LIG_SUMO_SIM_par_1	143	149	PF11976	0.424
LIG_SUMO_SIM_par_1	48	55	PF11976	0.424
LIG_TRAF2_1	182	185	PF00917	0.389
LIG_TYR_ITIM	512	517	PF00017	0.502
LIG_UBA3_1	160	165	PF00899	0.457
MOD_CDK_SPK_2	461	466	PF00069	0.502
MOD_CK1_1	116	122	PF00069	0.424
MOD_CK1_1	140	146	PF00069	0.521
MOD_CK1_1	348	354	PF00069	0.424
MOD_CK1_1	375	381	PF00069	0.442
MOD_CK1_1	530	536	PF00069	0.421
MOD_CK1_1	565	571	PF00069	0.390
MOD_CK1_1	57	63	PF00069	0.424
MOD_CK1_1	604	610	PF00069	0.435
MOD_CK1_1	662	668	PF00069	0.502
MOD_CK2_1	160	166	PF00069	0.450
MOD_CK2_1	179	185	PF00069	0.230
MOD_CK2_1	248	254	PF00069	0.490
MOD_CK2_1	292	298	PF00069	0.502
MOD_CK2_1	381	387	PF00069	0.357
MOD_CK2_1	85	91	PF00069	0.424
MOD_CK2_1	9	15	PF00069	0.522
MOD_DYRK1A_RPxSP_1	697	701	PF00069	0.542
MOD_GlcNHglycan	179	182	PF01048	0.340
MOD_GlcNHglycan	200	203	PF01048	0.455
MOD_GlcNHglycan	266	269	PF01048	0.228
MOD_GlcNHglycan	350	353	PF01048	0.224
MOD_GlcNHglycan	377	380	PF01048	0.491
MOD_GlcNHglycan	56	59	PF01048	0.224
MOD_GSK3_1	112	119	PF00069	0.408
MOD_GSK3_1	15	22	PF00069	0.438
MOD_GSK3_1	280	287	PF00069	0.393
MOD_GSK3_1	338	345	PF00069	0.424
MOD_GSK3_1	41	48	PF00069	0.395
MOD_GSK3_1	526	533	PF00069	0.461
MOD_GSK3_1	54	61	PF00069	0.373
MOD_GSK3_1	643	650	PF00069	0.435
MOD_LATS_1	151	157	PF00433	0.565
MOD_N-GLC_1	439	444	PF02516	0.328
MOD_N-GLC_1	525	530	PF02516	0.426
MOD_NEK2_1	160	165	PF00069	0.413
MOD_NEK2_1	280	285	PF00069	0.486
MOD_NEK2_1	640	645	PF00069	0.424
MOD_NEK2_1	659	664	PF00069	0.423
MOD_NEK2_2	137	142	PF00069	0.382
MOD_PIKK_1	225	231	PF00454	0.343
MOD_PIKK_1	284	290	PF00454	0.521
MOD_PIKK_1	345	351	PF00454	0.424
MOD_PIKK_1	41	47	PF00454	0.485
MOD_PIKK_1	58	64	PF00454	0.342
MOD_PIKK_1	76	82	PF00454	0.424
MOD_PKA_1	557	563	PF00069	0.316
MOD_PKA_2	557	563	PF00069	0.523
MOD_PKA_2	692	698	PF00069	0.630
MOD_Plk_1	116	122	PF00069	0.484
MOD_Plk_1	151	157	PF00069	0.467
MOD_Plk_1	249	255	PF00069	0.466
MOD_Plk_1	310	316	PF00069	0.424
MOD_Plk_4	140	146	PF00069	0.424
MOD_Plk_4	338	344	PF00069	0.424
MOD_Plk_4	392	398	PF00069	0.415
MOD_Plk_4	418	424	PF00069	0.361
MOD_Plk_4	45	51	PF00069	0.266
MOD_Plk_4	456	462	PF00069	0.512
MOD_Plk_4	623	629	PF00069	0.424
MOD_Plk_4	643	649	PF00069	0.317
MOD_Plk_4	662	668	PF00069	0.435
MOD_ProDKin_1	342	348	PF00069	0.424
MOD_ProDKin_1	461	467	PF00069	0.435
MOD_ProDKin_1	485	491	PF00069	0.462
MOD_ProDKin_1	660	666	PF00069	0.449
MOD_ProDKin_1	697	703	PF00069	0.639
MOD_SUMO_rev_2	108	116	PF00179	0.521
MOD_SUMO_rev_2	180	188	PF00179	0.464
MOD_SUMO_rev_2	616	621	PF00179	0.435
TRG_DiLeu_BaEn_1	236	241	PF01217	0.449
TRG_DiLeu_BaEn_1	443	448	PF01217	0.427
TRG_DiLeu_BaEn_2	316	322	PF01217	0.382
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.435
TRG_ENDOCYTIC_2	142	145	PF00928	0.424
TRG_ENDOCYTIC_2	20	23	PF00928	0.358
TRG_ENDOCYTIC_2	281	284	PF00928	0.424
TRG_ENDOCYTIC_2	385	388	PF00928	0.340
TRG_ENDOCYTIC_2	46	49	PF00928	0.266
TRG_ENDOCYTIC_2	514	517	PF00928	0.403
TRG_ENDOCYTIC_2	549	552	PF00928	0.331
TRG_ER_diArg_1	361	364	PF00400	0.538
TRG_ER_diArg_1	498	501	PF00400	0.443
TRG_ER_diArg_1	556	558	PF00400	0.326
TRG_ER_diArg_1	572	574	PF00400	0.505
TRG_ER_diArg_1	589	591	PF00400	0.415
TRG_ER_diArg_1	630	632	PF00400	0.424
TRG_ER_diArg_1	684	686	PF00400	0.460
TRG_ER_diArg_1	81	83	PF00400	0.418
TRG_NES_CRM1_1	471	483	PF08389	0.424
TRG_NES_CRM1_1	510	523	PF08389	0.487
TRG_NLS_Bipartite_1	685	700	PF00514	0.499
TRG_NLS_MonoExtN_4	693	700	PF00514	0.610

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P437	Leptomonas seymouri	30%	69%
A0A0N0P5V0	Leptomonas seymouri	89%	100%
A0A0N0P8Y1	Leptomonas seymouri	42%	91%
A0A0N0P9D2	Leptomonas seymouri	38%	99%
A0A0N1IKA7	Leptomonas seymouri	37%	78%
A0A0N1PEU4	Leptomonas seymouri	35%	74%
A0A0S4IQ76	Bodo saltans	41%	99%
A0A0S4IR78	Bodo saltans	36%	80%
A0A0S4IS51	Bodo saltans	38%	90%
A0A0S4IWU8	Bodo saltans	36%	83%
A0A0S4J157	Bodo saltans	72%	100%
A0A0S4JCY8	Bodo saltans	42%	69%
A0A1X0NJ46	Trypanosomatidae	81%	99%
A0A1X0P0D7	Trypanosomatidae	39%	100%
A0A1X0P872	Trypanosomatidae	35%	80%
A0A1X0P9K6	Trypanosomatidae	43%	98%
A0A3Q8II71	Leishmania donovani	42%	100%
A0A3Q8IJ24	Leishmania donovani	36%	75%
A0A3Q8IWG4	Leishmania donovani	37%	100%
A0A3R7MA90	Trypanosoma rangeli	79%	98%
A0A3R7MM88	Trypanosoma rangeli	38%	100%
A0A3R7NT42	Trypanosoma rangeli	42%	99%
A0A422MXB1	Trypanosoma rangeli	43%	66%
A0A422N8L3	Trypanosoma rangeli	39%	69%
A0A422NK53	Trypanosoma rangeli	35%	100%
A4HAT8	Leishmania braziliensis	42%	100%
A4HME2	Leishmania braziliensis	93%	100%
A4HNU7	Leishmania braziliensis	36%	100%
A4HQ83	Leishmania braziliensis	37%	100%
A4IA06	Leishmania infantum	42%	100%
A4IB14	Leishmania infantum	100%	100%
A4ICP7	Leishmania infantum	36%	100%
A4IDY1	Leishmania infantum	37%	100%
C9ZMN0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	95%
C9ZNP6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	77%	96%
D0A2R5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	80%
D0A3F8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	66%
D0A429	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	93%
D0A778	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	67%
D4A2Z8	Rattus norvegicus	28%	70%
E9AEU3	Leishmania major	97%	100%
E9ASK7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AU01	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9B512	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B5Z9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
F4IE66	Arabidopsis thaliana	38%	98%
F4IJV4	Arabidopsis thaliana	45%	67%
F4ILR7	Arabidopsis thaliana	31%	71%
F4JMJ3	Arabidopsis thaliana	47%	80%
F4JRJ6	Arabidopsis thaliana	42%	100%
O22899	Arabidopsis thaliana	53%	97%
O35286	Mus musculus	51%	89%
O42945	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	49%	96%
O43143	Homo sapiens	51%	89%
O45244	Caenorhabditis elegans	44%	70%
O51767	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	34%	86%
O60231	Homo sapiens	46%	68%
P0C9A2	African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)	29%	73%
P0C9A3	African swine fever virus (isolate Warthog/Namibia/Wart80/1980)	29%	73%
P0C9A4	African swine fever virus (isolate Pig/Kenya/KEN-50/1950)	29%	73%
P20095	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	80%
P36009	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	96%
P53131	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	92%
Q03319	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	98%
Q10752	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	67%
Q1EHT7	Oryza sativa subsp. japonica	30%	70%
Q20875	Caenorhabditis elegans	50%	95%
Q3ZBE0	Bos taurus	32%	98%
Q4Q0J4	Leishmania major	38%	100%
Q4Q1Y9	Leishmania major	36%	100%
Q4Q2X4	Leishmania major	42%	100%
Q54NJ4	Dictyostelium discoideum	51%	97%
Q5R864	Pongo abelii	36%	90%
Q5RAZ4	Pongo abelii	51%	89%
Q5RBD4	Pongo abelii	43%	98%
Q5UQ96	Acanthamoeba polyphaga mimivirus	29%	100%
Q5XH12	Xenopus laevis	33%	94%
Q5XI69	Rattus norvegicus	35%	90%
Q6PE54	Mus musculus	36%	90%
Q767K6	Sus scrofa	46%	67%
Q7K3M5	Drosophila melanogaster	52%	97%
Q7L7V1	Homo sapiens	33%	95%
Q7YR39	Pan troglodytes	46%	67%
Q80VY9	Mus musculus	40%	100%
Q89443	African swine fever virus (strain Badajoz 1971 Vero-adapted)	29%	73%
Q8BZS9	Mus musculus	34%	95%
Q8IX18	Homo sapiens	36%	90%
Q8TE96	Homo sapiens	34%	98%
Q8V9U2	African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)	29%	73%
Q8VHK9	Mus musculus	28%	70%
Q8VY00	Arabidopsis thaliana	46%	67%
Q924H9	Mus musculus	32%	98%
Q93Y16	Arabidopsis thaliana	38%	100%
Q9BKQ8	Caenorhabditis elegans	39%	96%
Q9H2U1	Homo sapiens	28%	70%
Q9H5Z1	Homo sapiens	42%	100%
Q9H6R0	Homo sapiens	40%	100%
Q9HE06	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
Q9LZQ9	Arabidopsis thaliana	54%	97%
V5B3L7	Trypanosoma cruzi	38%	100%
V5BKH2	Trypanosoma cruzi	44%	92%
V5BPV3	Trypanosoma cruzi	43%	67%
V5BV22	Trypanosoma cruzi	35%	79%
V5C0I9	Trypanosoma cruzi	38%	90%
V5D886	Trypanosoma cruzi	77%	99%