Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X8W7_LEIDO

TriTrypDb:

LdBPK_350910.1 , LdCL_350013900 , LDHU3_35.1100

Length:

165


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

A0A3S7X8W7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8W7


Leishmania	From	To	Domain/Motif	Score
DEG_Nend_Nbox_1	1	3	PF02207	0.647
DEG_SPOP_SBC_1	77	81	PF00917	0.650
DOC_CYCLIN_yCln2_LP_2	47	53	PF00134	0.475
DOC_PP2B_LxvP_1	111	114	PF13499	0.547
DOC_USP7_MATH_1	153	157	PF00917	0.496
DOC_USP7_MATH_1	24	28	PF00917	0.548
DOC_USP7_MATH_1	83	87	PF00917	0.724
DOC_USP7_UBL2_3	159	163	PF12436	0.536
DOC_USP7_UBL2_3	6	10	PF12436	0.613
DOC_WW_Pin1_4	4	9	PF00397	0.583
DOC_WW_Pin1_4	46	51	PF00397	0.474
DOC_WW_Pin1_4	85	90	PF00397	0.734
LIG_Actin_RPEL_3	139	158	PF02755	0.369
LIG_LIR_Gen_1	108	115	PF02991	0.555
LIG_LIR_Nem_3	108	113	PF02991	0.516
LIG_LIR_Nem_3	27	32	PF02991	0.450
LIG_SH2_CRK	69	73	PF00017	0.526
LIG_SH2_STAP1	119	123	PF00017	0.368
LIG_SH3_3	86	92	PF00018	0.714
LIG_SUMO_SIM_par_1	138	144	PF11976	0.459
MOD_CDK_SPxK_1	4	10	PF00069	0.561
MOD_CK1_1	35	41	PF00069	0.591
MOD_CK1_1	4	10	PF00069	0.688
MOD_CK1_1	76	82	PF00069	0.693
MOD_CK1_1	85	91	PF00069	0.690
MOD_CK1_1	99	105	PF00069	0.601
MOD_GlcNHglycan	75	78	PF01048	0.554
MOD_GlcNHglycan	85	88	PF01048	0.614
MOD_GSK3_1	72	79	PF00069	0.480
MOD_GSK3_1	94	101	PF00069	0.676
MOD_N-GLC_1	35	40	PF02516	0.432
MOD_NEK2_1	1	6	PF00069	0.651
MOD_NEK2_1	51	56	PF00069	0.507
MOD_NEK2_1	72	77	PF00069	0.513
MOD_PIKK_1	145	151	PF00454	0.628
MOD_PKA_2	145	151	PF00069	0.384
MOD_Plk_1	129	135	PF00069	0.425
MOD_Plk_1	35	41	PF00069	0.453
MOD_Plk_4	153	159	PF00069	0.430
MOD_Plk_4	35	41	PF00069	0.569
MOD_ProDKin_1	4	10	PF00069	0.586
MOD_ProDKin_1	46	52	PF00069	0.478
MOD_ProDKin_1	85	91	PF00069	0.729
MOD_SUMO_rev_2	27	32	PF00179	0.551
MOD_SUMO_rev_2	97	102	PF00179	0.615
TRG_ENDOCYTIC_2	69	72	PF00928	0.521
TRG_NES_CRM1_1	131	144	PF08389	0.336


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3P8	Leptomonas seymouri	63%	93%
A0A1X0NIU2	Trypanosomatidae	37%	100%
A0A3R7KNC4	Trypanosoma rangeli	36%	96%
A4HMC0	Leishmania braziliensis	78%	100%
A4IAY6	Leishmania infantum	99%	100%
C9ZNI3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
E9AER4	Leishmania major	94%	100%
E9B5W9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
V5D1X1	Trypanosoma cruzi	35%	99%