LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7X8V2_LEIDO
TriTrypDb:
LdBPK_350820.1 , LdCL_350013000 , LDHU3_35.0980
Length:
998

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X8V2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8V2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 533 537 PF00656 0.588
CLV_C14_Caspase3-7 939 943 PF00656 0.682
CLV_C14_Caspase3-7 951 955 PF00656 0.514
CLV_NRD_NRD_1 104 106 PF00675 0.642
CLV_NRD_NRD_1 23 25 PF00675 0.474
CLV_NRD_NRD_1 691 693 PF00675 0.641
CLV_NRD_NRD_1 879 881 PF00675 0.617
CLV_PCSK_KEX2_1 104 106 PF00082 0.650
CLV_PCSK_KEX2_1 23 25 PF00082 0.474
CLV_PCSK_KEX2_1 669 671 PF00082 0.548
CLV_PCSK_KEX2_1 691 693 PF00082 0.641
CLV_PCSK_KEX2_1 879 881 PF00082 0.617
CLV_PCSK_PC1ET2_1 669 671 PF00082 0.471
CLV_PCSK_PC7_1 665 671 PF00082 0.445
CLV_PCSK_SKI1_1 151 155 PF00082 0.612
CLV_PCSK_SKI1_1 42 46 PF00082 0.442
CLV_PCSK_SKI1_1 665 669 PF00082 0.507
CLV_PCSK_SKI1_1 670 674 PF00082 0.568
CLV_PCSK_SKI1_1 791 795 PF00082 0.605
CLV_PCSK_SKI1_1 807 811 PF00082 0.565
CLV_PCSK_SKI1_1 862 866 PF00082 0.683
CLV_PCSK_SKI1_1 990 994 PF00082 0.491
CLV_Separin_Metazoa 961 965 PF03568 0.579
DEG_COP1_1 676 686 PF00400 0.548
DEG_SCF_FBW7_1 740 745 PF00400 0.741
DEG_SPOP_SBC_1 243 247 PF00917 0.637
DEG_SPOP_SBC_1 801 805 PF00917 0.635
DOC_CKS1_1 470 475 PF01111 0.688
DOC_CKS1_1 739 744 PF01111 0.641
DOC_CYCLIN_RxL_1 39 49 PF00134 0.443
DOC_CYCLIN_yCln2_LP_2 458 464 PF00134 0.563
DOC_MAPK_DCC_7 925 935 PF00069 0.654
DOC_MAPK_gen_1 925 935 PF00069 0.639
DOC_MAPK_MEF2A_6 928 935 PF00069 0.642
DOC_PP2B_LxvP_1 458 461 PF13499 0.626
DOC_PP2B_LxvP_1 917 920 PF13499 0.636
DOC_PP4_FxxP_1 86 89 PF00568 0.728
DOC_PP4_MxPP_1 838 841 PF00568 0.656
DOC_USP7_MATH_1 111 115 PF00917 0.674
DOC_USP7_MATH_1 133 137 PF00917 0.620
DOC_USP7_MATH_1 139 143 PF00917 0.653
DOC_USP7_MATH_1 178 182 PF00917 0.666
DOC_USP7_MATH_1 243 247 PF00917 0.637
DOC_USP7_MATH_1 356 360 PF00917 0.651
DOC_USP7_MATH_1 476 480 PF00917 0.686
DOC_USP7_MATH_1 490 494 PF00917 0.626
DOC_USP7_MATH_1 511 515 PF00917 0.592
DOC_USP7_MATH_1 582 586 PF00917 0.629
DOC_USP7_MATH_1 607 611 PF00917 0.654
DOC_USP7_MATH_1 639 643 PF00917 0.765
DOC_USP7_MATH_1 648 652 PF00917 0.599
DOC_USP7_MATH_1 682 686 PF00917 0.612
DOC_USP7_MATH_1 742 746 PF00917 0.629
DOC_USP7_MATH_1 753 757 PF00917 0.673
DOC_USP7_MATH_1 759 763 PF00917 0.762
DOC_USP7_MATH_1 813 817 PF00917 0.685
DOC_USP7_MATH_1 869 873 PF00917 0.670
DOC_USP7_MATH_1 938 942 PF00917 0.652
DOC_WW_Pin1_4 199 204 PF00397 0.656
DOC_WW_Pin1_4 245 250 PF00397 0.585
DOC_WW_Pin1_4 313 318 PF00397 0.631
DOC_WW_Pin1_4 469 474 PF00397 0.625
DOC_WW_Pin1_4 486 491 PF00397 0.495
DOC_WW_Pin1_4 541 546 PF00397 0.724
DOC_WW_Pin1_4 577 582 PF00397 0.598
DOC_WW_Pin1_4 723 728 PF00397 0.801
DOC_WW_Pin1_4 738 743 PF00397 0.657
DOC_WW_Pin1_4 926 931 PF00397 0.598
DOC_WW_Pin1_4 973 978 PF00397 0.564
LIG_14-3-3_CanoR_1 220 230 PF00244 0.626
LIG_14-3-3_CanoR_1 31 37 PF00244 0.462
LIG_14-3-3_CanoR_1 345 353 PF00244 0.683
LIG_14-3-3_CanoR_1 602 607 PF00244 0.654
LIG_14-3-3_CanoR_1 691 696 PF00244 0.721
LIG_14-3-3_CanoR_1 717 727 PF00244 0.671
LIG_14-3-3_CanoR_1 791 800 PF00244 0.654
LIG_14-3-3_CanoR_1 83 89 PF00244 0.669
LIG_14-3-3_CanoR_1 966 972 PF00244 0.605
LIG_Actin_WH2_2 7 25 PF00022 0.465
LIG_BIR_II_1 1 5 PF00653 0.563
LIG_BIR_III_3 1 5 PF00653 0.629
LIG_BIR_III_4 273 277 PF00653 0.662
LIG_BIR_III_4 751 755 PF00653 0.584
LIG_BIR_III_4 828 832 PF00653 0.696
LIG_BRCT_BRCA1_1 543 547 PF00533 0.619
LIG_BRCT_BRCA1_1 785 789 PF00533 0.654
LIG_BRCT_BRCA1_1 971 975 PF00533 0.597
LIG_deltaCOP1_diTrp_1 378 386 PF00928 0.557
LIG_deltaCOP1_diTrp_1 784 789 PF00928 0.656
LIG_FHA_1 263 269 PF00498 0.585
LIG_FHA_1 36 42 PF00498 0.464
LIG_FHA_1 498 504 PF00498 0.656
LIG_FHA_1 52 58 PF00498 0.480
LIG_FHA_1 551 557 PF00498 0.570
LIG_FHA_1 592 598 PF00498 0.608
LIG_FHA_1 776 782 PF00498 0.732
LIG_FHA_1 792 798 PF00498 0.521
LIG_FHA_1 95 101 PF00498 0.706
LIG_FHA_2 152 158 PF00498 0.604
LIG_FHA_2 533 539 PF00498 0.632
LIG_FHA_2 745 751 PF00498 0.670
LIG_Integrin_RGD_1 774 776 PF01839 0.704
LIG_LIR_Apic_2 922 926 PF02991 0.635
LIG_LIR_Gen_1 784 795 PF02991 0.654
LIG_LIR_Nem_3 378 383 PF02991 0.544
LIG_LIR_Nem_3 544 550 PF02991 0.617
LIG_LIR_Nem_3 784 790 PF02991 0.654
LIG_MYND_3 572 576 PF01753 0.520
LIG_Pex14_2 971 975 PF04695 0.572
LIG_SH2_GRB2like 37 40 PF00017 0.466
LIG_SH2_NCK_1 5 9 PF00017 0.528
LIG_SH2_NCK_1 886 890 PF00017 0.511
LIG_SH2_SRC 462 465 PF00017 0.563
LIG_SH2_SRC 577 580 PF00017 0.550
LIG_SH2_STAP1 327 331 PF00017 0.551
LIG_SH2_STAP1 37 41 PF00017 0.460
LIG_SH2_STAT3 13 16 PF00017 0.444
LIG_SH2_STAT3 232 235 PF00017 0.605
LIG_SH2_STAT5 13 16 PF00017 0.409
LIG_SH2_STAT5 37 40 PF00017 0.466
LIG_SH2_STAT5 462 465 PF00017 0.569
LIG_SH2_STAT5 5 8 PF00017 0.524
LIG_SH2_STAT5 51 54 PF00017 0.457
LIG_SH2_STAT5 577 580 PF00017 0.658
LIG_SH2_STAT5 592 595 PF00017 0.557
LIG_SH3_1 315 321 PF00018 0.696
LIG_SH3_2 317 322 PF14604 0.581
LIG_SH3_3 314 320 PF00018 0.695
LIG_SH3_3 417 423 PF00018 0.604
LIG_SH3_3 436 442 PF00018 0.649
LIG_SH3_3 443 449 PF00018 0.536
LIG_SH3_3 458 464 PF00018 0.591
LIG_SH3_3 470 476 PF00018 0.593
LIG_SH3_3 54 60 PF00018 0.498
LIG_SH3_3 552 558 PF00018 0.535
LIG_SH3_3 567 573 PF00018 0.529
LIG_SH3_3 576 582 PF00018 0.641
LIG_SH3_3 584 590 PF00018 0.528
LIG_SH3_3 593 599 PF00018 0.499
LIG_SH3_3 633 639 PF00018 0.634
LIG_SH3_3 721 727 PF00018 0.681
LIG_SH3_3 912 918 PF00018 0.621
LIG_Sin3_3 593 600 PF02671 0.604
LIG_SUMO_SIM_par_1 288 295 PF11976 0.616
LIG_UBA3_1 660 669 PF00899 0.483
LIG_WW_3 88 92 PF00397 0.658
MOD_CK1_1 138 144 PF00069 0.623
MOD_CK1_1 197 203 PF00069 0.628
MOD_CK1_1 218 224 PF00069 0.634
MOD_CK1_1 226 232 PF00069 0.751
MOD_CK1_1 245 251 PF00069 0.487
MOD_CK1_1 281 287 PF00069 0.716
MOD_CK1_1 346 352 PF00069 0.653
MOD_CK1_1 361 367 PF00069 0.533
MOD_CK1_1 401 407 PF00069 0.559
MOD_CK1_1 465 471 PF00069 0.625
MOD_CK1_1 499 505 PF00069 0.584
MOD_CK1_1 532 538 PF00069 0.637
MOD_CK1_1 677 683 PF00069 0.621
MOD_CK1_1 693 699 PF00069 0.623
MOD_CK1_1 726 732 PF00069 0.633
MOD_CK1_1 820 826 PF00069 0.655
MOD_CK1_1 885 891 PF00069 0.710
MOD_CK2_1 151 157 PF00069 0.607
MOD_CK2_1 221 227 PF00069 0.640
MOD_CK2_1 386 392 PF00069 0.525
MOD_CK2_1 532 538 PF00069 0.599
MOD_CK2_1 954 960 PF00069 0.589
MOD_Cter_Amidation 102 105 PF01082 0.652
MOD_Cter_Amidation 689 692 PF01082 0.621
MOD_GlcNHglycan 107 110 PF01048 0.689
MOD_GlcNHglycan 111 114 PF01048 0.641
MOD_GlcNHglycan 118 121 PF01048 0.572
MOD_GlcNHglycan 137 140 PF01048 0.562
MOD_GlcNHglycan 141 144 PF01048 0.664
MOD_GlcNHglycan 161 164 PF01048 0.462
MOD_GlcNHglycan 180 183 PF01048 0.507
MOD_GlcNHglycan 196 199 PF01048 0.528
MOD_GlcNHglycan 270 273 PF01048 0.683
MOD_GlcNHglycan 283 286 PF01048 0.553
MOD_GlcNHglycan 294 297 PF01048 0.749
MOD_GlcNHglycan 338 341 PF01048 0.668
MOD_GlcNHglycan 345 348 PF01048 0.604
MOD_GlcNHglycan 358 361 PF01048 0.528
MOD_GlcNHglycan 403 406 PF01048 0.556
MOD_GlcNHglycan 435 438 PF01048 0.672
MOD_GlcNHglycan 439 442 PF01048 0.598
MOD_GlcNHglycan 478 481 PF01048 0.670
MOD_GlcNHglycan 513 516 PF01048 0.550
MOD_GlcNHglycan 584 587 PF01048 0.716
MOD_GlcNHglycan 641 644 PF01048 0.772
MOD_GlcNHglycan 680 683 PF01048 0.671
MOD_GlcNHglycan 684 687 PF01048 0.666
MOD_GlcNHglycan 720 723 PF01048 0.625
MOD_GlcNHglycan 744 747 PF01048 0.640
MOD_GlcNHglycan 755 758 PF01048 0.678
MOD_GlcNHglycan 832 837 PF01048 0.649
MOD_GlcNHglycan 86 89 PF01048 0.654
MOD_GlcNHglycan 871 874 PF01048 0.590
MOD_GlcNHglycan 938 941 PF01048 0.623
MOD_GlcNHglycan 950 953 PF01048 0.494
MOD_GlcNHglycan 971 974 PF01048 0.580
MOD_GSK3_1 105 112 PF00069 0.596
MOD_GSK3_1 131 138 PF00069 0.689
MOD_GSK3_1 192 199 PF00069 0.625
MOD_GSK3_1 231 238 PF00069 0.736
MOD_GSK3_1 243 250 PF00069 0.701
MOD_GSK3_1 264 271 PF00069 0.611
MOD_GSK3_1 3 10 PF00069 0.502
MOD_GSK3_1 341 348 PF00069 0.646
MOD_GSK3_1 386 393 PF00069 0.502
MOD_GSK3_1 394 401 PF00069 0.554
MOD_GSK3_1 433 440 PF00069 0.716
MOD_GSK3_1 462 469 PF00069 0.595
MOD_GSK3_1 486 493 PF00069 0.579
MOD_GSK3_1 497 504 PF00069 0.655
MOD_GSK3_1 539 546 PF00069 0.584
MOD_GSK3_1 673 680 PF00069 0.587
MOD_GSK3_1 708 715 PF00069 0.597
MOD_GSK3_1 738 745 PF00069 0.637
MOD_GSK3_1 759 766 PF00069 0.637
MOD_GSK3_1 791 798 PF00069 0.660
MOD_GSK3_1 808 815 PF00069 0.698
MOD_GSK3_1 881 888 PF00069 0.609
MOD_GSK3_1 969 976 PF00069 0.590
MOD_N-GLC_1 215 220 PF02516 0.634
MOD_N-GLC_1 432 437 PF02516 0.625
MOD_N-GLC_1 550 555 PF02516 0.536
MOD_N-GLC_1 889 894 PF02516 0.606
MOD_N-GLC_1 954 959 PF02516 0.643
MOD_N-GLC_1 973 978 PF02516 0.578
MOD_N-GLC_2 166 168 PF02516 0.612
MOD_NEK2_1 137 142 PF00069 0.573
MOD_NEK2_1 196 201 PF00069 0.628
MOD_NEK2_1 231 236 PF00069 0.679
MOD_NEK2_1 336 341 PF00069 0.600
MOD_NEK2_1 343 348 PF00069 0.593
MOD_NEK2_1 351 356 PF00069 0.521
MOD_NEK2_1 386 391 PF00069 0.529
MOD_NEK2_1 550 555 PF00069 0.623
MOD_NEK2_1 668 673 PF00069 0.532
MOD_NEK2_1 94 99 PF00069 0.689
MOD_NEK2_1 948 953 PF00069 0.562
MOD_NEK2_1 991 996 PF00069 0.583
MOD_OFUCOSY 168 174 PF10250 0.594
MOD_PIKK_1 231 237 PF00454 0.601
MOD_PIKK_1 24 30 PF00454 0.436
MOD_PIKK_1 58 64 PF00454 0.539
MOD_PIKK_1 94 100 PF00454 0.678
MOD_PKA_1 691 697 PF00069 0.627
MOD_PKA_2 159 165 PF00069 0.618
MOD_PKA_2 30 36 PF00069 0.482
MOD_PKA_2 601 607 PF00069 0.542
MOD_PKA_2 631 637 PF00069 0.617
MOD_PKA_2 690 696 PF00069 0.673
MOD_PKA_2 820 826 PF00069 0.755
MOD_PKA_2 869 875 PF00069 0.600
MOD_PKA_2 913 919 PF00069 0.606
MOD_PKA_2 967 973 PF00069 0.614
MOD_Plk_1 215 221 PF00069 0.625
MOD_Plk_1 226 232 PF00069 0.647
MOD_Plk_1 539 545 PF00069 0.544
MOD_Plk_1 550 556 PF00069 0.537
MOD_Plk_1 783 789 PF00069 0.611
MOD_Plk_1 881 887 PF00069 0.524
MOD_Plk_1 889 895 PF00069 0.492
MOD_Plk_2-3 278 284 PF00069 0.658
MOD_Plk_4 226 232 PF00069 0.686
MOD_Plk_4 264 270 PF00069 0.584
MOD_Plk_4 902 908 PF00069 0.663
MOD_Plk_4 919 925 PF00069 0.524
MOD_ProDKin_1 199 205 PF00069 0.656
MOD_ProDKin_1 245 251 PF00069 0.587
MOD_ProDKin_1 313 319 PF00069 0.629
MOD_ProDKin_1 469 475 PF00069 0.626
MOD_ProDKin_1 486 492 PF00069 0.496
MOD_ProDKin_1 541 547 PF00069 0.725
MOD_ProDKin_1 577 583 PF00069 0.599
MOD_ProDKin_1 723 729 PF00069 0.802
MOD_ProDKin_1 738 744 PF00069 0.655
MOD_ProDKin_1 926 932 PF00069 0.600
MOD_ProDKin_1 973 979 PF00069 0.556
MOD_SUMO_rev_2 762 771 PF00179 0.628
TRG_DiLeu_BaEn_1 981 986 PF01217 0.542
TRG_DiLeu_BaEn_2 381 387 PF01217 0.590
TRG_ER_diArg_1 104 106 PF00400 0.566
TRG_ER_diArg_1 22 24 PF00400 0.474
TRG_ER_diArg_1 303 306 PF00400 0.614
TRG_ER_diArg_1 560 563 PF00400 0.544
TRG_ER_diArg_1 879 881 PF00400 0.617
TRG_ER_diArg_1 90 93 PF00400 0.696
TRG_ER_diArg_1 963 966 PF00400 0.629
TRG_ER_diArg_1 988 991 PF00400 0.480

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P5D3 Leptomonas seymouri 30% 100%
A4HMB1 Leishmania braziliensis 57% 95%
A4IAX7 Leishmania infantum 99% 100%
E9AEQ5 Leishmania major 83% 99%
E9B5W0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 98%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS