Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X8T7_LEIDO

TriTrypDb:

LdBPK_350460.1 , LdCL_350009800 , LDHU3_35.0630

Length:

220

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X8T7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8T7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	133	135	PF00675	0.694
CLV_NRD_NRD_1	146	148	PF00675	0.635
CLV_PCSK_KEX2_1	133	135	PF00082	0.694
CLV_PCSK_KEX2_1	146	148	PF00082	0.647
CLV_PCSK_KEX2_1	166	168	PF00082	0.627
CLV_PCSK_PC1ET2_1	166	168	PF00082	0.723
CLV_PCSK_SKI1_1	161	165	PF00082	0.685
CLV_PCSK_SKI1_1	88	92	PF00082	0.368
DEG_Nend_UBRbox_2	1	3	PF02207	0.722
DOC_CYCLIN_yCln2_LP_2	14	20	PF00134	0.673
DOC_MAPK_gen_1	88	94	PF00069	0.496
DOC_PP2B_LxvP_1	14	17	PF13499	0.772
DOC_PP4_FxxP_1	107	110	PF00568	0.620
DOC_USP7_MATH_1	188	192	PF00917	0.510
DOC_USP7_MATH_2	50	56	PF00917	0.680
DOC_WW_Pin1_4	190	195	PF00397	0.502
DOC_WW_Pin1_4	20	25	PF00397	0.795
DOC_WW_Pin1_4	61	66	PF00397	0.692
LIG_14-3-3_CanoR_1	10	15	PF00244	0.783
LIG_14-3-3_CanoR_1	190	194	PF00244	0.505
LIG_Actin_WH2_2	93	111	PF00022	0.329
LIG_FHA_1	103	109	PF00498	0.469
LIG_FHA_1	176	182	PF00498	0.534
LIG_FHA_1	49	55	PF00498	0.778
LIG_FHA_2	175	181	PF00498	0.498
LIG_LIR_Apic_2	105	110	PF02991	0.616
LIG_LIR_Apic_2	132	138	PF02991	0.533
LIG_SH2_CRK	115	119	PF00017	0.505
LIG_SH2_SRC	135	138	PF00017	0.536
LIG_SH2_STAP1	115	119	PF00017	0.505
LIG_SH2_STAT5	106	109	PF00017	0.506
LIG_SH2_STAT5	115	118	PF00017	0.420
LIG_SH2_STAT5	135	138	PF00017	0.440
LIG_SH3_2	195	200	PF14604	0.458
LIG_SH3_3	191	197	PF00018	0.520
LIG_SH3_3	44	50	PF00018	0.693
LIG_SH3_3	64	70	PF00018	0.684
LIG_SUMO_SIM_anti_2	74	81	PF11976	0.662
LIG_TRAF2_1	211	214	PF00917	0.450
LIG_TRFH_1	106	110	PF08558	0.619
LIG_TYR_ITIM	113	118	PF00017	0.503
LIG_UBA3_1	80	89	PF00899	0.614
LIG_WRC_WIRS_1	114	119	PF05994	0.517
MOD_CDK_SPxxK_3	20	27	PF00069	0.776
MOD_CK1_1	121	127	PF00069	0.484
MOD_CK1_1	142	148	PF00069	0.572
MOD_CK1_1	172	178	PF00069	0.497
MOD_CK1_1	31	37	PF00069	0.796
MOD_CK1_1	98	104	PF00069	0.334
MOD_CK2_1	174	180	PF00069	0.497
MOD_CK2_1	20	26	PF00069	0.773
MOD_DYRK1A_RPxSP_1	190	194	PF00069	0.505
MOD_GlcNHglycan	10	13	PF01048	0.611
MOD_GlcNHglycan	120	123	PF01048	0.633
MOD_GlcNHglycan	148	151	PF01048	0.698
MOD_GlcNHglycan	155	158	PF01048	0.664
MOD_GlcNHglycan	207	210	PF01048	0.655
MOD_GlcNHglycan	33	36	PF01048	0.595
MOD_GlcNHglycan	37	40	PF01048	0.544
MOD_GlcNHglycan	54	57	PF01048	0.616
MOD_GSK3_1	113	120	PF00069	0.409
MOD_GSK3_1	121	128	PF00069	0.460
MOD_GSK3_1	142	149	PF00069	0.564
MOD_GSK3_1	153	160	PF00069	0.450
MOD_GSK3_1	16	23	PF00069	0.716
MOD_GSK3_1	172	179	PF00069	0.403
MOD_GSK3_1	29	36	PF00069	0.798
MOD_GSK3_1	48	55	PF00069	0.727
MOD_GSK3_1	95	102	PF00069	0.334
MOD_LATS_1	137	143	PF00433	0.494
MOD_NEK2_1	117	122	PF00069	0.347
MOD_NEK2_1	151	156	PF00069	0.551
MOD_NEK2_1	29	34	PF00069	0.719
MOD_NEK2_1	99	104	PF00069	0.342
MOD_PIKK_1	108	114	PF00454	0.499
MOD_PKA_1	146	152	PF00069	0.510
MOD_PKA_2	108	114	PF00069	0.444
MOD_PKA_2	146	152	PF00069	0.510
MOD_PKA_2	183	189	PF00069	0.546
MOD_Plk_4	10	16	PF00069	0.697
MOD_Plk_4	102	108	PF00069	0.421
MOD_Plk_4	113	119	PF00069	0.345
MOD_Plk_4	121	127	PF00069	0.454
MOD_Plk_4	95	101	PF00069	0.421
MOD_ProDKin_1	190	196	PF00069	0.500
MOD_ProDKin_1	20	26	PF00069	0.796
MOD_ProDKin_1	61	67	PF00069	0.692
TRG_DiLeu_BaEn_1	74	79	PF01217	0.629
TRG_DiLeu_BaEn_2	86	92	PF01217	0.728
TRG_DiLeu_BaLyEn_6	73	78	PF01217	0.770
TRG_ENDOCYTIC_2	115	118	PF00928	0.457
TRG_ER_diArg_1	133	135	PF00400	0.494
TRG_ER_diArg_1	146	148	PF00400	0.435
TRG_NES_CRM1_1	75	87	PF08389	0.621

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HM82	Leishmania braziliensis	40%	100%
A4IAU6	Leishmania infantum	100%	100%
E9AEM4	Leishmania major	73%	100%