Proteophosphoglycan ppg3, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

proteophosphoglycan ppg4 (fragment)

Species:

Leishmania donovani

UniProt:

A0A3S7X8R4_LEIDO

TriTrypDb:

LdBPK_350490.1 , LdBPK_350500.1 , LdCL_350010100 , LDHU3_35.0660

Length:

4997

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 1, no: 0
NetGPI	no	yes: 0, no: 1

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Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	2
GO:0016020	membrane	2	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	2

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Expansion

Sequence features

A0A3S7X8R4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0002218	activation of innate immune response	3	2
GO:0002221	pattern recognition receptor signaling pathway	5	2
GO:0002224	toll-like receptor signaling pathway	6	2
GO:0002253	activation of immune response	2	2
GO:0002376	immune system process	1	2
GO:0002682	regulation of immune system process	3	2
GO:0002684	positive regulation of immune system process	4	2
GO:0002757	immune response-activating signaling pathway	3	2
GO:0002758	innate immune response-activating signaling pathway	4	2
GO:0002764	immune response-regulating signaling pathway	3	2

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Molecular functions
Term	Name	Level	Count
GO:0004888	transmembrane signaling receptor activity	3	2
GO:0038023	signaling receptor activity	2	2
GO:0060089	molecular transducer activity	1	2

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	504	508	PF00656	0.214
CLV_NRD_NRD_1	1429	1431	PF00675	0.328
CLV_NRD_NRD_1	1471	1473	PF00675	0.380
CLV_NRD_NRD_1	1474	1476	PF00675	0.398
CLV_NRD_NRD_1	1477	1479	PF00675	0.390
CLV_NRD_NRD_1	1486	1488	PF00675	0.312
CLV_NRD_NRD_1	1594	1596	PF00675	0.348
CLV_NRD_NRD_1	1597	1599	PF00675	0.335
CLV_NRD_NRD_1	1605	1607	PF00675	0.264
CLV_NRD_NRD_1	1653	1655	PF00675	0.409

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
Q06852	ACET2	24%	100%
Q9LHP4	ARATH	25%	100%

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