Tc-38 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X8M8_LEIDO

TriTrypDb:

LdBPK_350160.1 , LdCL_350006600 , LDHU3_35.0230

Length:

315

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X8M8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8M8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	138	142	PF00656	0.305
CLV_NRD_NRD_1	205	207	PF00675	0.554
CLV_NRD_NRD_1	266	268	PF00675	0.413
CLV_NRD_NRD_1	4	6	PF00675	0.581
CLV_PCSK_KEX2_1	266	268	PF00082	0.660
CLV_PCSK_KEX2_1	4	6	PF00082	0.581
CLV_PCSK_SKI1_1	103	107	PF00082	0.554
CLV_PCSK_SKI1_1	11	15	PF00082	0.545
CLV_PCSK_SKI1_1	207	211	PF00082	0.522
CLV_PCSK_SKI1_1	266	270	PF00082	0.527

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P611	Leptomonas seymouri	64%	96%
A0A0S4JHS2	Bodo saltans	32%	81%
A0A1X0NJ57	Trypanosomatidae	44%	100%
A0A3R7LQI0	Trypanosoma rangeli	46%	100%
A4HM55	Leishmania braziliensis	86%	100%
A4IAR7	Leishmania infantum	100%	100%
D0A2E5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E9AEJ3	Leishmania major	93%	100%
E9B5Q4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
V5DJR0	Trypanosoma cruzi	48%	100%

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