Phosphoglycan beta 1,3 galactosyltransferase 4

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphoglycan beta 1,3 galactosyltransferase 4

Species:

Leishmania donovani

UniProt:

A0A3S7X8M5_LEIDO

TriTrypDb:

LdCL_350005000 , LDHU3_31.5600

Length:

360

Annotations

LeishMANIAdb annotations

Phosphoglycan beta 1,3 galactosyltransferase (required for proper protective coat formation). Probably part of a much larger group. Expanded in Leishmaniids. Localization: Golgi (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3S7X8M5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8M5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	3
GO:0016740	transferase activity	2	3
GO:0016757	glycosyltransferase activity	3	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	284	286	PF00675	0.616
CLV_NRD_NRD_1	71	73	PF00675	0.444
CLV_NRD_NRD_1	93	95	PF00675	0.470
CLV_PCSK_KEX2_1	106	108	PF00082	0.224
CLV_PCSK_KEX2_1	284	286	PF00082	0.616
CLV_PCSK_KEX2_1	93	95	PF00082	0.470
CLV_PCSK_PC1ET2_1	106	108	PF00082	0.271
CLV_PCSK_PC7_1	89	95	PF00082	0.436
CLV_PCSK_SKI1_1	106	110	PF00082	0.271
CLV_Separin_Metazoa	269	273	PF03568	0.406
DEG_Nend_UBRbox_1	1	4	PF02207	0.704
DOC_CYCLIN_yCln2_LP_2	249	255	PF00134	0.406
DOC_MAPK_gen_1	106	114	PF00069	0.471
DOC_MAPK_gen_1	298	307	PF00069	0.397
DOC_MAPK_HePTP_8	104	116	PF00069	0.471
DOC_MAPK_JIP1_4	298	304	PF00069	0.443
DOC_MAPK_MEF2A_6	106	114	PF00069	0.471
DOC_MAPK_MEF2A_6	298	307	PF00069	0.397
DOC_PP4_FxxP_1	153	156	PF00568	0.446
DOC_SPAK_OSR1_1	107	111	PF12202	0.299
DOC_USP7_MATH_1	222	226	PF00917	0.458
DOC_USP7_MATH_1	241	245	PF00917	0.353
DOC_USP7_MATH_1	256	260	PF00917	0.380
DOC_USP7_MATH_1	289	293	PF00917	0.467
DOC_USP7_MATH_1	37	41	PF00917	0.686
DOC_USP7_MATH_1	59	63	PF00917	0.660
DOC_USP7_MATH_1	92	96	PF00917	0.665
DOC_WW_Pin1_4	124	129	PF00397	0.481
DOC_WW_Pin1_4	152	157	PF00397	0.465
LIG_14-3-3_CanoR_1	149	157	PF00244	0.451
LIG_14-3-3_CanoR_1	323	327	PF00244	0.357
LIG_14-3-3_CanoR_1	93	101	PF00244	0.651
LIG_Clathr_ClatBox_1	185	189	PF01394	0.419
LIG_FHA_1	195	201	PF00498	0.382
LIG_FHA_1	259	265	PF00498	0.399
LIG_FHA_1	338	344	PF00498	0.347
LIG_FHA_2	326	332	PF00498	0.365
LIG_LIR_Apic_2	151	156	PF02991	0.450
LIG_LIR_Gen_1	155	161	PF02991	0.518
LIG_LIR_Gen_1	206	217	PF02991	0.410
LIG_LIR_Nem_3	155	160	PF02991	0.518
LIG_LIR_Nem_3	165	170	PF02991	0.459
LIG_LIR_Nem_3	206	212	PF02991	0.413
LIG_LIR_Nem_3	325	329	PF02991	0.361
LIG_NRBOX	111	117	PF00104	0.299
LIG_PDZ_Class_2	355	360	PF00595	0.405
LIG_Pex14_2	153	157	PF04695	0.439
LIG_PTB_Apo_2	208	215	PF02174	0.405
LIG_PTB_Phospho_1	208	214	PF10480	0.404
LIG_SH2_STAP1	214	218	PF00017	0.405
LIG_SH2_STAT3	280	283	PF00017	0.426
LIG_SH2_STAT5	347	350	PF00017	0.357
LIG_SH3_3	302	308	PF00018	0.391
LIG_TYR_ITIM	327	332	PF00017	0.367
MOD_CK1_1	127	133	PF00069	0.455
MOD_CK1_1	155	161	PF00069	0.444
MOD_CK1_1	292	298	PF00069	0.454
MOD_CK1_1	62	68	PF00069	0.686
MOD_CK2_1	162	168	PF00069	0.437
MOD_CK2_1	325	331	PF00069	0.370
MOD_CK2_1	33	39	PF00069	0.775
MOD_GlcNHglycan	132	135	PF01048	0.645
MOD_GlcNHglycan	164	167	PF01048	0.625
MOD_GlcNHglycan	215	218	PF01048	0.607
MOD_GlcNHglycan	220	223	PF01048	0.623
MOD_GlcNHglycan	243	246	PF01048	0.630
MOD_GlcNHglycan	35	38	PF01048	0.482
MOD_GlcNHglycan	39	42	PF01048	0.477
MOD_GlcNHglycan	65	68	PF01048	0.480
MOD_GlcNHglycan	94	97	PF01048	0.463
MOD_GSK3_1	124	131	PF00069	0.516
MOD_GSK3_1	148	155	PF00069	0.438
MOD_GSK3_1	218	225	PF00069	0.433
MOD_GSK3_1	235	242	PF00069	0.375
MOD_GSK3_1	33	40	PF00069	0.776
MOD_GSK3_1	54	61	PF00069	0.699
MOD_GSK3_1	62	69	PF00069	0.685
MOD_GSK3_1	74	81	PF00069	0.691
MOD_N-GLC_1	128	133	PF02516	0.628
MOD_N-GLC_1	210	215	PF02516	0.613
MOD_N-GLC_1	337	342	PF02516	0.553
MOD_NEK2_1	170	175	PF00069	0.421
MOD_NEK2_1	24	29	PF00069	0.642
MOD_NEK2_1	240	245	PF00069	0.416
MOD_NEK2_2	194	199	PF00069	0.414
MOD_PIKK_1	132	138	PF00454	0.487
MOD_PIKK_1	170	176	PF00454	0.425
MOD_PIKK_1	25	31	PF00454	0.639
MOD_PIKK_1	287	293	PF00454	0.465
MOD_PIKK_1	78	84	PF00454	0.644
MOD_PIKK_1	99	105	PF00454	0.609
MOD_PK_1	235	241	PF00069	0.430
MOD_PKA_2	13	19	PF00069	0.695
MOD_PKA_2	148	154	PF00069	0.450
MOD_PKA_2	223	229	PF00069	0.459
MOD_PKA_2	292	298	PF00069	0.454
MOD_PKA_2	322	328	PF00069	0.359
MOD_PKA_2	353	359	PF00069	0.395
MOD_PKA_2	92	98	PF00069	0.662
MOD_Plk_1	203	209	PF00069	0.406
MOD_Plk_1	210	216	PF00069	0.389
MOD_Plk_4	181	187	PF00069	0.442
MOD_Plk_4	235	241	PF00069	0.430
MOD_Plk_4	322	328	PF00069	0.359
MOD_ProDKin_1	124	130	PF00069	0.491
MOD_ProDKin_1	152	158	PF00069	0.464
TRG_DiLeu_BaLyEn_6	136	141	PF01217	0.455
TRG_ENDOCYTIC_2	329	332	PF00928	0.372
TRG_ER_diArg_1	284	286	PF00400	0.416
TRG_ER_diArg_1	92	94	PF00400	0.669
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.656
TRG_Pf-PMV_PEXEL_1	199	203	PF00026	0.601

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4ICY7	Leishmania infantum	85%	100%