Pyruvate kinase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Pyruvate kinase

Gene product:

pyruvate kinase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X8M0_LEIDO

TriTrypDb:

LdBPK_055450.1 , LdCL_350005200 , LDHU3_35.0050

Length:

507

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 1
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 2
Forrest at al. (procyclic)	no	yes: 2
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 24

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 17
NetGPI	no	yes: 0, no: 17

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3S7X8M0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8M0

Function

Biological processes
Term	Name	Level	Count
GO:0005975	carbohydrate metabolic process	3	2
GO:0006082	organic acid metabolic process	3	2
GO:0006090	pyruvate metabolic process	7	2
GO:0006091	generation of precursor metabolites and energy	3	2
GO:0006096	glycolytic process	5	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006163	purine nucleotide metabolic process	5	2
GO:0006165	obsolete nucleoside diphosphate phosphorylation	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006753	nucleoside phosphate metabolic process	4	2
GO:0006757	obsolete ATP generation from ADP	4	2
GO:0006793	phosphorus metabolic process	3	2
GO:0006796	phosphate-containing compound metabolic process	4	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009056	catabolic process	2	2
GO:0009117	nucleotide metabolic process	5	2
GO:0009132	nucleoside diphosphate metabolic process	5	2
GO:0009135	purine nucleoside diphosphate metabolic process	6	2
GO:0009141	nucleoside triphosphate metabolic process	5	2
GO:0009144	purine nucleoside triphosphate metabolic process	6	2
GO:0009150	purine ribonucleotide metabolic process	6	2
GO:0009179	purine ribonucleoside diphosphate metabolic process	7	2
GO:0009185	ribonucleoside diphosphate metabolic process	6	2
GO:0009199	ribonucleoside triphosphate metabolic process	6	2
GO:0009205	purine ribonucleoside triphosphate metabolic process	7	2
GO:0009259	ribonucleotide metabolic process	5	2
GO:0009987	cellular process	1	2
GO:0016052	carbohydrate catabolic process	4	2
GO:0016310	phosphorylation	5	2
GO:0019637	organophosphate metabolic process	3	2
GO:0019693	ribose phosphate metabolic process	4	2
GO:0019752	carboxylic acid metabolic process	5	2
GO:0032787	monocarboxylic acid metabolic process	6	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0043436	oxoacid metabolic process	4	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044281	small molecule metabolic process	2	2
GO:0046031	ADP metabolic process	7	2
GO:0046034	ATP metabolic process	7	2
GO:0046483	heterocycle metabolic process	3	2
GO:0046939	obsolete nucleotide phosphorylation	6	2
GO:0055086	nucleobase-containing small molecule metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0072521	purine-containing compound metabolic process	4	2
GO:1901135	carbohydrate derivative metabolic process	3	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901564	organonitrogen compound metabolic process	3	2
GO:1901575	organic substance catabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	18
GO:0000287	magnesium ion binding	5	18
GO:0003824	catalytic activity	1	18
GO:0004743	pyruvate kinase activity	5	18
GO:0005488	binding	1	18
GO:0005524	ATP binding	5	18
GO:0016301	kinase activity	4	18
GO:0016740	transferase activity	2	18
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	18
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	18
GO:0017076	purine nucleotide binding	4	18
GO:0030554	adenyl nucleotide binding	5	18
GO:0030955	potassium ion binding	6	18
GO:0031420	alkali metal ion binding	5	18
GO:0032553	ribonucleotide binding	3	18
GO:0032555	purine ribonucleotide binding	4	18
GO:0032559	adenyl ribonucleotide binding	5	18
GO:0035639	purine ribonucleoside triphosphate binding	4	18
GO:0036094	small molecule binding	2	18
GO:0043167	ion binding	2	18
GO:0043168	anion binding	3	18
GO:0043169	cation binding	3	18
GO:0046872	metal ion binding	4	18
GO:0097159	organic cyclic compound binding	2	18
GO:0097367	carbohydrate derivative binding	2	18
GO:1901265	nucleoside phosphate binding	3	18
GO:1901363	heterocyclic compound binding	2	18
GO:0043531	ADP binding	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	199	203	PF00656	0.338
CLV_C14_Caspase3-7	262	266	PF00656	0.468
CLV_NRD_NRD_1	183	185	PF00675	0.254
CLV_PCSK_KEX2_1	183	185	PF00082	0.294
CLV_PCSK_SKI1_1	112	116	PF00082	0.346
CLV_PCSK_SKI1_1	232	236	PF00082	0.261
DEG_Nend_Nbox_1	1	3	PF02207	0.608
DOC_MAPK_gen_1	142	152	PF00069	0.527
DOC_MAPK_gen_1	238	245	PF00069	0.417
DOC_MAPK_gen_1	401	408	PF00069	0.485
DOC_MAPK_gen_1	462	472	PF00069	0.448
DOC_MAPK_MEF2A_6	11	20	PF00069	0.270
DOC_MAPK_MEF2A_6	271	278	PF00069	0.447
DOC_MAPK_MEF2A_6	401	408	PF00069	0.498
DOC_MAPK_MEF2A_6	422	430	PF00069	0.498
DOC_MAPK_MEF2A_6	465	472	PF00069	0.432
DOC_USP7_MATH_1	196	200	PF00917	0.416
DOC_USP7_MATH_1	320	324	PF00917	0.447
DOC_USP7_MATH_1	388	392	PF00917	0.446
DOC_USP7_MATH_1	393	397	PF00917	0.447
LIG_14-3-3_CanoR_1	3	8	PF00244	0.391
LIG_14-3-3_CanoR_1	433	442	PF00244	0.449
LIG_14-3-3_CanoR_1	497	506	PF00244	0.298
LIG_14-3-3_CanoR_1	58	68	PF00244	0.441
LIG_BRCT_BRCA1_1	447	451	PF00533	0.546
LIG_FHA_1	113	119	PF00498	0.484
LIG_FHA_1	15	21	PF00498	0.457
LIG_FHA_1	28	34	PF00498	0.396
LIG_FHA_1	303	309	PF00498	0.447
LIG_FHA_1	38	44	PF00498	0.378
LIG_FHA_1	429	435	PF00498	0.466
LIG_FHA_1	441	447	PF00498	0.416
LIG_FHA_2	177	183	PF00498	0.531
LIG_FHA_2	316	322	PF00498	0.447
LIG_FHA_2	500	506	PF00498	0.300
LIG_Integrin_RGD_1	271	273	PF01839	0.247
LIG_KLC1_Yacidic_2	131	136	PF13176	0.447
LIG_LIR_Gen_1	136	144	PF02991	0.519
LIG_LIR_Gen_1	148	157	PF02991	0.546
LIG_LIR_Gen_1	215	225	PF02991	0.447
LIG_LIR_Gen_1	368	375	PF02991	0.500
LIG_LIR_Nem_3	131	137	PF02991	0.468
LIG_LIR_Nem_3	148	152	PF02991	0.447
LIG_LIR_Nem_3	19	24	PF02991	0.365
LIG_LIR_Nem_3	215	221	PF02991	0.447
LIG_LIR_Nem_3	368	372	PF02991	0.501
LIG_LRP6_Inhibitor_1	370	376	PF00058	0.348
LIG_MLH1_MIPbox_1	447	451	PF16413	0.546
LIG_PCNA_yPIPBox_3	357	370	PF02747	0.546
LIG_PTB_Apo_2	324	331	PF02174	0.481
LIG_SH2_CRK	137	141	PF00017	0.546
LIG_SH2_GRB2like	137	140	PF00017	0.546
LIG_SH2_PTP2	149	152	PF00017	0.546
LIG_SH2_SRC	149	152	PF00017	0.546
LIG_SH2_STAP1	398	402	PF00017	0.481
LIG_SH2_STAT5	117	120	PF00017	0.517
LIG_SH2_STAT5	134	137	PF00017	0.378
LIG_SH2_STAT5	149	152	PF00017	0.447
LIG_SH2_STAT5	369	372	PF00017	0.452
LIG_SH3_1	420	426	PF00018	0.447
LIG_SH3_3	140	146	PF00018	0.535
LIG_SH3_3	183	189	PF00018	0.465
LIG_SH3_3	190	196	PF00018	0.420
LIG_SH3_3	273	279	PF00018	0.456
LIG_SH3_3	420	426	PF00018	0.447
LIG_SUMO_SIM_anti_2	153	160	PF11976	0.546
LIG_SUMO_SIM_anti_2	241	246	PF11976	0.468
LIG_SUMO_SIM_par_1	16	22	PF11976	0.512
LIG_SUMO_SIM_par_1	404	409	PF11976	0.438
LIG_SUMO_SIM_par_1	483	489	PF11976	0.560
LIG_TRAF2_1	384	387	PF00917	0.438
LIG_TYR_ITIM	135	140	PF00017	0.456
LIG_UBA3_1	242	247	PF00899	0.468
LIG_UBA3_1	503	507	PF00899	0.298
LIG_WRC_WIRS_1	218	223	PF05994	0.447
MOD_CK1_1	339	345	PF00069	0.447
MOD_CK1_1	39	45	PF00069	0.418
MOD_CK1_1	52	58	PF00069	0.454
MOD_CK1_1	62	68	PF00069	0.455
MOD_CK2_1	16	22	PF00069	0.383
MOD_CK2_1	256	262	PF00069	0.516
MOD_CK2_1	315	321	PF00069	0.447
MOD_CK2_1	381	387	PF00069	0.415
MOD_CK2_1	393	399	PF00069	0.410
MOD_CK2_1	499	505	PF00069	0.306
MOD_GlcNHglycan	198	201	PF01048	0.327
MOD_GlcNHglycan	223	226	PF01048	0.346
MOD_GlcNHglycan	338	341	PF01048	0.247
MOD_GlcNHglycan	363	366	PF01048	0.247
MOD_GlcNHglycan	383	386	PF01048	0.206
MOD_GlcNHglycan	391	394	PF01048	0.228
MOD_GlcNHglycan	413	416	PF01048	0.271
MOD_GlcNHglycan	480	483	PF01048	0.201
MOD_GlcNHglycan	51	54	PF01048	0.218
MOD_GSK3_1	112	119	PF00069	0.498
MOD_GSK3_1	166	173	PF00069	0.546
MOD_GSK3_1	217	224	PF00069	0.456
MOD_GSK3_1	3	10	PF00069	0.376
MOD_GSK3_1	32	39	PF00069	0.418
MOD_GSK3_1	389	396	PF00069	0.452
MOD_GSK3_1	429	436	PF00069	0.451
MOD_N-GLC_1	138	143	PF02516	0.274
MOD_N-GLC_1	14	19	PF02516	0.408
MOD_N-GLC_1	440	445	PF02516	0.281
MOD_N-GLC_1	59	64	PF02516	0.240
MOD_NEK2_1	16	21	PF00069	0.500
MOD_NEK2_1	170	175	PF00069	0.546
MOD_NEK2_1	307	312	PF00069	0.455
MOD_NEK2_1	371	376	PF00069	0.373
MOD_NEK2_1	408	413	PF00069	0.451
MOD_NEK2_1	440	445	PF00069	0.452
MOD_NEK2_1	472	477	PF00069	0.524
MOD_NEK2_1	49	54	PF00069	0.431
MOD_NEK2_1	59	64	PF00069	0.453
MOD_NEK2_1	7	12	PF00069	0.547
MOD_NEK2_2	393	398	PF00069	0.481
MOD_NEK2_2	445	450	PF00069	0.546
MOD_PIKK_1	302	308	PF00454	0.451
MOD_PIKK_1	37	43	PF00454	0.410
MOD_PIKK_1	440	446	PF00454	0.510
MOD_PKA_2	27	33	PF00069	0.291
MOD_PKA_2	315	321	PF00069	0.447
MOD_PKA_2	69	75	PF00069	0.410
MOD_PKB_1	3	11	PF00069	0.367
MOD_Plk_1	14	20	PF00069	0.413
MOD_Plk_1	166	172	PF00069	0.447
MOD_Plk_4	145	151	PF00069	0.464
MOD_Plk_4	16	22	PF00069	0.356
MOD_Plk_4	217	223	PF00069	0.447
MOD_Plk_4	256	262	PF00069	0.495
MOD_Plk_4	393	399	PF00069	0.481
MOD_Plk_4	445	451	PF00069	0.472
MOD_Plk_4	499	505	PF00069	0.343
MOD_SUMO_rev_2	396	402	PF00179	0.501
TRG_DiLeu_BaEn_3	262	268	PF01217	0.546
TRG_ENDOCYTIC_2	137	140	PF00928	0.459
TRG_ENDOCYTIC_2	149	152	PF00928	0.447
TRG_ENDOCYTIC_2	369	372	PF00928	0.452
TRG_ER_diArg_1	2	5	PF00400	0.428

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBX8	Leptomonas seymouri	87%	100%
A0A0S4JHN6	Bodo saltans	65%	100%
A0A1X0P7Q1	Trypanosomatidae	77%	100%
A0A3Q8IES7	Leishmania donovani	98%	100%
A0A422NPT0	Trypanosoma rangeli	75%	100%
A4HM36	Leishmania braziliensis	91%	100%
A4HM39	Leishmania braziliensis	92%	100%
A4HM41	Leishmania braziliensis	91%	100%
A4IAQ1	Leishmania infantum	98%	100%
A4IAQ4	Leishmania infantum	99%	100%
B0B7Q0	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)	41%	100%
B8BJ39	Oryza sativa subsp. indica	35%	96%
B8BM17	Oryza sativa subsp. indica	35%	96%
C9ZZZ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
C9ZZZ1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	100%
E9AEH9	Leishmania major	95%	100%
E9AEI0	Leishmania major	98%	100%
E9B5P1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
O05118	Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1)	37%	100%
O08309	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	41%	100%
O44006	Eimeria tenella	47%	95%
O51323	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	38%	100%
O62619	Drosophila melanogaster	51%	95%
O65595	Arabidopsis thaliana	48%	100%
O94122	Agaricus bisporus	51%	95%
P00548	Gallus gallus	49%	96%
P00549	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	100%
P0AD61	Escherichia coli (strain K12)	47%	100%
P0AD62	Escherichia coli O157:H7	47%	100%
P0CE21	Chlamydia trachomatis (strain D/UW-3/Cx)	41%	100%
P11974	Oryctolagus cuniculus	49%	95%
P11979	Felis catus	49%	95%
P11980	Rattus norvegicus	50%	95%
P12928	Rattus norvegicus	48%	88%
P14618	Homo sapiens	50%	95%
P21599	Escherichia coli (strain K12)	36%	100%
P22200	Solanum tuberosum	47%	99%
P22360	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	51%	96%
P30613	Homo sapiens	49%	88%
P30614	Yarrowia lipolytica (strain CLIB 122 / E 150)	50%	98%
P30615	Trypanosoma brucei brucei	75%	100%
P30616	Trypanosoma brucei brucei	75%	100%
P31865	Hypocrea jecorina	48%	94%
P32044	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	34%	93%
P34038	Lactobacillus delbrueckii subsp. bulgaricus	40%	86%
P43924	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	37%	100%
P46614	Candida albicans (strain SC5314 / ATCC MYA-2876)	51%	100%
P47458	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	38%	100%
P51181	Bacillus licheniformis	48%	87%
P51182	Sporosarcina psychrophila	46%	87%
P52480	Mus musculus	50%	95%
P52489	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	100%
P53657	Mus musculus	48%	88%
P55964	Ricinus communis	37%	100%
P57404	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	33%	100%
P70789	Agrobacterium vitis	39%	100%
P73534	Synechocystis sp. (strain PCC 6803 / Kazusa)	42%	86%
P77983	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	45%	100%
P78031	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	37%	100%
P80885	Bacillus subtilis (strain 168)	48%	87%
P94939	Mycobacterium intracellulare	38%	100%
P9WKE4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	39%	100%
P9WKE5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	39%	100%
Q02499	Geobacillus stearothermophilus	46%	86%
Q07637	Lactococcus lactis subsp. lactis (strain IL1403)	37%	100%
Q10208	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	53%	100%
Q12669	Aspergillus niger	51%	96%
Q27686	Leishmania mexicana	93%	100%
Q27788	Trypanoplasma borreli	58%	100%
Q29536	Canis lupus familiaris	49%	88%
Q2FG40	Staphylococcus aureus (strain USA300)	46%	87%
Q2FXM9	Staphylococcus aureus (strain NCTC 8325 / PS 47)	46%	87%
Q2QXR8	Oryza sativa subsp. japonica	35%	96%
Q2RAK2	Oryza sativa subsp. japonica	35%	96%
Q2YTE3	Staphylococcus aureus (strain bovine RF122 / ET3-1)	46%	87%
Q40545	Nicotiana tabacum	33%	85%
Q40546	Nicotiana tabacum	38%	90%
Q42806	Glycine max	48%	99%
Q42954	Nicotiana tabacum	43%	100%
Q43117	Ricinus communis	33%	87%
Q44473	Agrobacterium vitis	37%	100%
Q46078	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	39%	100%
Q46289	Clostridium perfringens (strain 13 / Type A)	43%	100%
Q49YC7	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	45%	87%
Q4L739	Staphylococcus haemolyticus (strain JCSC1435)	45%	87%
Q54RF5	Dictyostelium discoideum	51%	100%
Q55863	Synechocystis sp. (strain PCC 6803 / Kazusa)	39%	100%
Q56301	Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C)	37%	100%
Q57572	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	33%	100%
Q5HF76	Staphylococcus aureus (strain COL)	46%	87%
Q5HNK7	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	45%	87%
Q5NVN0	Pongo abelii	49%	95%
Q6BS75	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	49%	100%
Q6FIS9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	53%	100%
Q6FV12	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	49%	100%
Q6G8M9	Staphylococcus aureus (strain MSSA476)	46%	87%
Q6GG09	Staphylococcus aureus (strain MRSA252)	46%	87%
Q759A9	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	51%	100%
Q7A0N4	Staphylococcus aureus (strain MW2)	46%	87%
Q7A559	Staphylococcus aureus (strain N315)	46%	87%
Q7RVA8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	48%	96%
Q875M9	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	49%	100%
Q875S4	Lachancea kluyveri (strain ATCC 58438 / CBS 3082 / BCRC 21498 / NBRC 1685 / JCM 7257 / NCYC 543 / NRRL Y-12651)	49%	100%
Q875Z9	Naumovozyma castellii (strain ATCC 76901 / BCRC 22586 / CBS 4309 / NBRC 1992 / NRRL Y-12630)	50%	100%
Q89AI8	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	34%	100%
Q8CS69	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	45%	87%
Q8FP04	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	41%	100%
Q8K9M3	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	35%	100%
Q8SQP0	Encephalitozoon cuniculi (strain GB-M1)	37%	100%
Q8Z6K2	Salmonella typhi	45%	100%
Q8ZNW0	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	37%	100%
Q8ZYE0	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	27%	100%
Q92122	Xenopus laevis	50%	96%
Q93Z53	Arabidopsis thaliana	37%	89%
Q99TG5	Staphylococcus aureus (strain Mu50 / ATCC 700699)	46%	87%
Q9FLW9	Arabidopsis thaliana	36%	88%
Q9LIK0	Arabidopsis thaliana	34%	85%
Q9PK61	Chlamydia muridarum (strain MoPn / Nigg)	42%	100%
Q9WY51	Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)	35%	100%
Q9YEU2	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	35%	100%
Q9Z984	Chlamydia pneumoniae	38%	100%
V5C1M1	Trypanosoma cruzi	75%	100%