Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X8J2_LEIDO

TriTrypDb:

LdBPK_344030.1 , LdCL_340049700 , LDHU3_34.6340

Length:

221

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X8J2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8J2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	113	115	PF00675	0.534
CLV_NRD_NRD_1	71	73	PF00675	0.602
CLV_PCSK_KEX2_1	71	73	PF00082	0.602
CLV_PCSK_SKI1_1	115	119	PF00082	0.421
CLV_PCSK_SKI1_1	193	197	PF00082	0.537
DEG_APCC_DBOX_1	113	121	PF00400	0.535
DEG_SCF_FBW7_1	211	217	PF00400	0.619
DOC_CKS1_1	211	216	PF01111	0.615
DOC_CYCLIN_RxL_1	111	122	PF00134	0.534
DOC_MAPK_gen_1	191	200	PF00069	0.547
DOC_MAPK_gen_1	26	34	PF00069	0.506
DOC_MAPK_MEF2A_6	193	202	PF00069	0.536
DOC_PP1_RVXF_1	113	120	PF00149	0.535
DOC_USP7_MATH_1	138	142	PF00917	0.561
DOC_USP7_MATH_1	214	218	PF00917	0.702
DOC_USP7_MATH_1	35	39	PF00917	0.655
DOC_USP7_MATH_1	99	103	PF00917	0.506
DOC_USP7_MATH_2	164	170	PF00917	0.538
DOC_WW_Pin1_4	127	132	PF00397	0.429
DOC_WW_Pin1_4	160	165	PF00397	0.516
DOC_WW_Pin1_4	207	212	PF00397	0.631
LIG_14-3-3_CanoR_1	177	187	PF00244	0.507
LIG_14-3-3_CanoR_1	193	202	PF00244	0.444
LIG_deltaCOP1_diTrp_1	149	154	PF00928	0.549
LIG_FHA_2	183	189	PF00498	0.620
LIG_LIR_Gen_1	165	176	PF02991	0.594
LIG_LIR_Nem_3	122	127	PF02991	0.581
LIG_LIR_Nem_3	165	171	PF02991	0.588
LIG_PDZ_Class_2	216	221	PF00595	0.720
LIG_Pex14_1	150	154	PF04695	0.551
LIG_Pex14_2	146	150	PF04695	0.493
LIG_Pex14_2	154	158	PF04695	0.598
LIG_Pex14_2	40	44	PF04695	0.631
LIG_PTB_Apo_2	7	14	PF02174	0.565
LIG_SH2_CRK	136	140	PF00017	0.566
LIG_SH2_STAT5	116	119	PF00017	0.538
LIG_SH2_STAT5	124	127	PF00017	0.437
LIG_SH2_STAT5	57	60	PF00017	0.514
LIG_SH3_2	21	26	PF14604	0.513
LIG_SH3_3	128	134	PF00018	0.437
LIG_SH3_3	18	24	PF00018	0.615
LIG_SH3_3	208	214	PF00018	0.647
MOD_CK1_1	210	216	PF00069	0.650
MOD_CK2_1	1	7	PF00069	0.636
MOD_CK2_1	160	166	PF00069	0.519
MOD_GlcNHglycan	101	104	PF01048	0.517
MOD_GSK3_1	166	173	PF00069	0.552
MOD_GSK3_1	178	185	PF00069	0.489
MOD_GSK3_1	210	217	PF00069	0.621
MOD_N-GLC_2	98	100	PF02516	0.353
MOD_NEK2_1	139	144	PF00069	0.557
MOD_NEK2_1	47	52	PF00069	0.525
MOD_NEK2_2	35	40	PF00069	0.626
MOD_PIKK_1	214	220	PF00454	0.551
MOD_PKA_2	27	33	PF00069	0.565
MOD_PKA_2	58	64	PF00069	0.627
MOD_Plk_1	47	53	PF00069	0.511
MOD_Plk_2-3	63	69	PF00069	0.613
MOD_Plk_4	35	41	PF00069	0.648
MOD_ProDKin_1	127	133	PF00069	0.426
MOD_ProDKin_1	160	166	PF00069	0.519
MOD_ProDKin_1	207	213	PF00069	0.637
MOD_SUMO_rev_2	188	192	PF00179	0.649
TRG_ENDOCYTIC_2	136	139	PF00928	0.561
TRG_NES_CRM1_1	137	149	PF08389	0.493

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4KLZ9	Bodo saltans	27%	94%
A4HBE3	Leishmania braziliensis	76%	100%
A4IAJ1	Leishmania infantum	100%	100%
E9B5L5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4Q2C1	Leishmania major	90%	100%