LeishMANIAdb
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Dolichol phosphate-mannose biosynthesis regulatory protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Dolichol phosphate-mannose biosynthesis regulatory protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X8J1_LEIDO
TriTrypDb:
LdBPK_343780.1 * , LdCL_340047200 , LDHU3_34.6060
Length:
94

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0016020 membrane 2 5
GO:0110165 cellular anatomical entity 1 5

Expansion

Sequence features

A0A3S7X8J1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8J1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 38 42 PF00082 0.521
DEG_Nend_Nbox_1 1 3 PF02207 0.798
DEG_SPOP_SBC_1 54 58 PF00917 0.311
DOC_MAPK_MEF2A_6 8 15 PF00069 0.745
DOC_PP2B_LxvP_1 2 5 PF13499 0.772
DOC_WW_Pin1_4 45 50 PF00397 0.359
LIG_DCNL_PONY_1 1 4 PF03556 0.789
LIG_eIF4E_1 7 13 PF01652 0.694
LIG_FHA_1 55 61 PF00498 0.389
LIG_FHA_1 81 87 PF00498 0.489
LIG_LIR_Apic_2 48 54 PF02991 0.380
LIG_LIR_Nem_3 63 68 PF02991 0.435
LIG_LIR_Nem_3 87 91 PF02991 0.636
LIG_NRBOX 22 28 PF00104 0.394
LIG_PCNA_yPIPBox_3 8 16 PF02747 0.689
LIG_SH2_PTP2 51 54 PF00017 0.380
LIG_SH2_STAP1 82 86 PF00017 0.530
LIG_SH2_STAT3 7 10 PF00017 0.700
LIG_SH2_STAT5 51 54 PF00017 0.380
LIG_SH2_STAT5 66 69 PF00017 0.284
LIG_SH2_STAT5 82 85 PF00017 0.327
LIG_SH3_3 65 71 PF00018 0.452
LIG_SUMO_SIM_anti_2 29 35 PF11976 0.413
MOD_CDK_SPK_2 45 50 PF00069 0.283
MOD_CK1_1 80 86 PF00069 0.530
MOD_CMANNOS 85 88 PF00535 0.530
MOD_GSK3_1 77 84 PF00069 0.530
MOD_N-GLC_1 54 59 PF02516 0.524
MOD_NEK2_1 26 31 PF00069 0.316
MOD_NEK2_1 77 82 PF00069 0.530
MOD_Plk_4 29 35 PF00069 0.413
MOD_Plk_4 77 83 PF00069 0.530
MOD_ProDKin_1 45 51 PF00069 0.359

Homologs

Protein Taxonomy Sequence identity Coverage
A4HBB7 Leishmania braziliensis 74% 100%
A4IAG6 Leishmania infantum 99% 100%
E9B5J0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4Q2E6 Leishmania major 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS