Dolichol phosphate-mannose biosynthesis regulatory protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X8J1_LEIDO

TriTrypDb:

LdBPK_343780.1 , LdCL_340047200 , LDHU3_34.6060

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	5
GO:0110165	cellular anatomical entity	1	5

A0A3S7X8J1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X8J1


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	38	42	PF00082	0.521
DEG_Nend_Nbox_1	1	3	PF02207	0.798
DEG_SPOP_SBC_1	54	58	PF00917	0.311
DOC_MAPK_MEF2A_6	8	15	PF00069	0.745
DOC_PP2B_LxvP_1	2	5	PF13499	0.772
DOC_WW_Pin1_4	45	50	PF00397	0.359
LIG_DCNL_PONY_1	1	4	PF03556	0.789
LIG_eIF4E_1	7	13	PF01652	0.694
LIG_FHA_1	55	61	PF00498	0.389
LIG_FHA_1	81	87	PF00498	0.489
LIG_LIR_Apic_2	48	54	PF02991	0.380
LIG_LIR_Nem_3	63	68	PF02991	0.435
LIG_LIR_Nem_3	87	91	PF02991	0.636
LIG_NRBOX	22	28	PF00104	0.394
LIG_PCNA_yPIPBox_3	8	16	PF02747	0.689
LIG_SH2_PTP2	51	54	PF00017	0.380
LIG_SH2_STAP1	82	86	PF00017	0.530
LIG_SH2_STAT3	7	10	PF00017	0.700
LIG_SH2_STAT5	51	54	PF00017	0.380
LIG_SH2_STAT5	66	69	PF00017	0.284
LIG_SH2_STAT5	82	85	PF00017	0.327
LIG_SH3_3	65	71	PF00018	0.452
LIG_SUMO_SIM_anti_2	29	35	PF11976	0.413
MOD_CDK_SPK_2	45	50	PF00069	0.283
MOD_CK1_1	80	86	PF00069	0.530
MOD_CMANNOS	85	88	PF00535	0.530
MOD_GSK3_1	77	84	PF00069	0.530
MOD_N-GLC_1	54	59	PF02516	0.524
MOD_NEK2_1	26	31	PF00069	0.316
MOD_NEK2_1	77	82	PF00069	0.530
MOD_Plk_4	29	35	PF00069	0.413
MOD_Plk_4	77	83	PF00069	0.530
MOD_ProDKin_1	45	51	PF00069	0.359


Protein	Taxonomy	Sequence identity	Coverage
A4HBB7	Leishmania braziliensis	74%	100%
A4IAG6	Leishmania infantum	99%	100%
E9B5J0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q2E6	Leishmania major	93%	100%