Unc104-like kinesin, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Unc104-like kinesin, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X8I6_LEIDO

TriTrypDb:

LdBPK_332690.1 , LdCL_340050300 , LDHU3_34.6400

Length:

1488

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	6
GO:0005871	kinesin complex	3	1
GO:0005874	microtubule	6	1
GO:0005875	microtubule associated complex	2	1
GO:0016020	membrane	2	6
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	6
GO:0043227	membrane-bounded organelle	3	6
GO:0043229	intracellular organelle	3	6
GO:0043231	intracellular membrane-bounded organelle	4	6

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Expansion

Sequence features

A0A3S7X8I6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	7
GO:0007017	microtubule-based process	2	7
GO:0007018	microtubule-based movement	3	7
GO:0009987	cellular process	1	7
GO:0010970	transport along microtubule	4	7
GO:0016043	cellular component organization	3	6
GO:0030705	cytoskeleton-dependent intracellular transport	4	7
GO:0046907	intracellular transport	3	7
GO:0047496	vesicle transport along microtubule	5	7
GO:0051179	localization	1	7

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003774	cytoskeletal motor activity	1	7
GO:0003777	microtubule motor activity	2	7
GO:0003824	catalytic activity	1	1
GO:0005488	binding	1	7
GO:0005515	protein binding	2	7
GO:0005524	ATP binding	5	7
GO:0008017	microtubule binding	5	7
GO:0008092	cytoskeletal protein binding	3	7
GO:0015631	tubulin binding	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	1053	1055	PF00675	0.354
CLV_NRD_NRD_1	1379	1381	PF00675	0.277
CLV_NRD_NRD_1	1461	1463	PF00675	0.294
CLV_NRD_NRD_1	440	442	PF00675	0.657
CLV_NRD_NRD_1	448	450	PF00675	0.495
CLV_NRD_NRD_1	672	674	PF00675	0.563
CLV_NRD_NRD_1	717	719	PF00675	0.431
CLV_NRD_NRD_1	752	754	PF00675	0.540
CLV_NRD_NRD_1	861	863	PF00675	0.384
CLV_NRD_NRD_1	883	885	PF00675	0.336

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7F2	Leptomonas seymouri	63%	98%
A4HBE9	Leishmania braziliensis	74%	100%
A4IAJ7	Leishmania infantum	99%	100%
E9B5M1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q2B5	Leishmania major	93%	100%

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