LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X896_LEIDO
TriTrypDb:
LdBPK_343100.1 , LdCL_340039900 , LDHU3_34.5260
Length:
153

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X896
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X896

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 139 141 PF00675 0.747
CLV_NRD_NRD_1 142 144 PF00675 0.689
CLV_NRD_NRD_1 3 5 PF00675 0.556
CLV_PCSK_FUR_1 140 144 PF00082 0.683
CLV_PCSK_KEX2_1 139 141 PF00082 0.747
CLV_PCSK_KEX2_1 142 144 PF00082 0.689
CLV_PCSK_KEX2_1 3 5 PF00082 0.556
CLV_PCSK_KEX2_1 71 73 PF00082 0.457
CLV_PCSK_PC1ET2_1 71 73 PF00082 0.509
CLV_PCSK_SKI1_1 146 150 PF00082 0.706
CLV_PCSK_SKI1_1 4 8 PF00082 0.644
CLV_PCSK_SKI1_1 66 70 PF00082 0.483
DEG_Nend_Nbox_1 1 3 PF02207 0.618
DOC_MAPK_gen_1 107 117 PF00069 0.556
DOC_MAPK_gen_1 3 9 PF00069 0.622
DOC_MAPK_gen_1 88 95 PF00069 0.564
DOC_PP1_RVXF_1 111 118 PF00149 0.582
DOC_USP7_MATH_1 26 30 PF00917 0.717
DOC_WW_Pin1_4 41 46 PF00397 0.560
LIG_14-3-3_CanoR_1 63 69 PF00244 0.584
LIG_FHA_2 82 88 PF00498 0.456
LIG_SH2_STAP1 125 129 PF00017 0.599
LIG_SUMO_SIM_par_1 38 44 PF11976 0.611
MOD_CK1_1 44 50 PF00069 0.515
MOD_GlcNHglycan 133 137 PF01048 0.626
MOD_GlcNHglycan 14 17 PF01048 0.742
MOD_GlcNHglycan 28 31 PF01048 0.642
MOD_GSK3_1 8 15 PF00069 0.620
MOD_NEK2_1 117 122 PF00069 0.549
MOD_NEK2_1 9 14 PF00069 0.620
MOD_NEK2_1 95 100 PF00069 0.535
MOD_PIKK_1 32 38 PF00454 0.686
MOD_PKA_1 142 148 PF00069 0.648
MOD_PKA_2 142 148 PF00069 0.648
MOD_PKB_1 140 148 PF00069 0.645
MOD_Plk_4 44 50 PF00069 0.442
MOD_Plk_4 95 101 PF00069 0.482
MOD_ProDKin_1 41 47 PF00069 0.552
MOD_SUMO_rev_2 120 130 PF00179 0.588
MOD_SUMO_rev_2 145 150 PF00179 0.657
MOD_SUMO_rev_2 55 60 PF00179 0.419
TRG_ENDOCYTIC_2 53 56 PF00928 0.441
TRG_ENDOCYTIC_2 92 95 PF00928 0.499
TRG_ER_diArg_1 139 142 PF00400 0.760
TRG_ER_diArg_1 2 4 PF00400 0.553
TRG_NLS_MonoExtC_3 69 75 PF00514 0.517
TRG_Pf-PMV_PEXEL_1 71 75 PF00026 0.467

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P447 Leptomonas seymouri 80% 100%
A0A1X0PAS5 Trypanosomatidae 60% 100%
A4HB51 Leishmania braziliensis 80% 100%
A4IA99 Leishmania infantum 99% 100%
E9B5C1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q2L2 Leishmania major 89% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS