Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X828_LEIDO

TriTrypDb:

LdBPK_342570.1 , LdCL_340033300 , LDHU3_34.4180

Length:

184

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X828

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X828

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	14	18	PF00656	0.708
CLV_NRD_NRD_1	163	165	PF00675	0.651
CLV_NRD_NRD_1	32	34	PF00675	0.513
CLV_PCSK_KEX2_1	32	34	PF00082	0.513
CLV_PCSK_SKI1_1	23	27	PF00082	0.684
CLV_PCSK_SKI1_1	83	87	PF00082	0.706
DEG_SCF_FBW7_1	110	117	PF00400	0.781
DEG_SCF_FBW7_1	24	30	PF00400	0.681
DEG_SCF_FBW7_1	70	77	PF00400	0.630
DOC_CDC14_PxL_1	134	142	PF14671	0.771
DOC_CKS1_1	111	116	PF01111	0.781
DOC_CKS1_1	24	29	PF01111	0.672
DOC_PP4_FxxP_1	107	110	PF00568	0.772
DOC_PP4_FxxP_1	21	24	PF00568	0.645
DOC_USP7_MATH_1	10	14	PF00917	0.717
DOC_USP7_MATH_1	100	104	PF00917	0.739
DOC_USP7_MATH_1	148	152	PF00917	0.749
DOC_USP7_MATH_1	156	160	PF00917	0.611
DOC_USP7_MATH_1	48	52	PF00917	0.602
DOC_USP7_MATH_1	74	78	PF00917	0.728
DOC_USP7_UBL2_3	95	99	PF12436	0.688
DOC_WW_Pin1_4	102	107	PF00397	0.719
DOC_WW_Pin1_4	110	115	PF00397	0.459
DOC_WW_Pin1_4	121	126	PF00397	0.752
DOC_WW_Pin1_4	140	145	PF00397	0.793
DOC_WW_Pin1_4	146	151	PF00397	0.707
DOC_WW_Pin1_4	23	28	PF00397	0.656
DOC_WW_Pin1_4	35	40	PF00397	0.621
DOC_WW_Pin1_4	44	49	PF00397	0.596
DOC_WW_Pin1_4	59	64	PF00397	0.723
DOC_WW_Pin1_4	70	75	PF00397	0.497
LIG_BRCT_BRCA1_1	17	21	PF00533	0.717
LIG_BRCT_BRCA1_2	17	23	PF00533	0.657
LIG_DCNL_PONY_1	1	4	PF03556	0.722
LIG_FHA_1	60	66	PF00498	0.731
LIG_FHA_1	88	94	PF00498	0.534
LIG_FHA_2	45	51	PF00498	0.688
LIG_LIR_Apic_2	104	110	PF02991	0.761
LIG_LIR_Apic_2	18	24	PF02991	0.633
LIG_LIR_Nem_3	50	56	PF02991	0.564
LIG_NRBOX	92	98	PF00104	0.610
LIG_Pex14_2	21	25	PF04695	0.740
LIG_SH2_NCK_1	56	60	PF00017	0.728
LIG_SH2_STAT5	11	14	PF00017	0.680
LIG_SH3_1	33	39	PF00018	0.627
LIG_SH3_3	176	182	PF00018	0.605
LIG_SH3_3	21	27	PF00018	0.646
LIG_SH3_3	33	39	PF00018	0.507
LIG_UBA3_1	93	99	PF00899	0.602
MOD_CDK_SPK_2	27	32	PF00069	0.517
MOD_CDK_SPxK_1	110	116	PF00069	0.700
MOD_CDK_SPxK_1	140	146	PF00069	0.794
MOD_CDK_SPxK_1	27	33	PF00069	0.631
MOD_CDK_SPxK_1	70	76	PF00069	0.632
MOD_CDK_SPxxK_3	146	153	PF00069	0.799
MOD_CK1_1	124	130	PF00069	0.778
MOD_CK1_1	139	145	PF00069	0.698
MOD_CK1_1	149	155	PF00069	0.754
MOD_CK1_1	15	21	PF00069	0.599
MOD_CK1_1	44	50	PF00069	0.538
MOD_CK1_1	5	11	PF00069	0.604
MOD_CK1_1	98	104	PF00069	0.625
MOD_CK2_1	139	145	PF00069	0.698
MOD_DYRK1A_RPxSP_1	146	150	PF00069	0.799
MOD_GlcNHglycan	158	161	PF01048	0.673
MOD_GlcNHglycan	174	177	PF01048	0.651
MOD_GlcNHglycan	4	7	PF01048	0.732
MOD_GSK3_1	106	113	PF00069	0.673
MOD_GSK3_1	11	18	PF00069	0.605
MOD_GSK3_1	117	124	PF00069	0.729
MOD_GSK3_1	132	139	PF00069	0.484
MOD_GSK3_1	23	30	PF00069	0.559
MOD_GSK3_1	44	51	PF00069	0.544
MOD_GSK3_1	70	77	PF00069	0.630
MOD_GSK3_1	98	105	PF00069	0.617
MOD_NEK2_1	41	46	PF00069	0.619
MOD_NEK2_2	48	53	PF00069	0.608
MOD_OFUCOSY	40	45	PF10250	0.717
MOD_PIKK_1	87	93	PF00454	0.669
MOD_PKA_2	172	178	PF00069	0.603
MOD_Plk_1	48	54	PF00069	0.585
MOD_Plk_4	124	130	PF00069	0.778
MOD_Plk_4	48	54	PF00069	0.582
MOD_ProDKin_1	102	108	PF00069	0.723
MOD_ProDKin_1	110	116	PF00069	0.462
MOD_ProDKin_1	121	127	PF00069	0.752
MOD_ProDKin_1	140	146	PF00069	0.794
MOD_ProDKin_1	23	29	PF00069	0.654
MOD_ProDKin_1	35	41	PF00069	0.621
MOD_ProDKin_1	44	50	PF00069	0.597
MOD_ProDKin_1	59	65	PF00069	0.727
MOD_ProDKin_1	70	76	PF00069	0.499
TRG_DiLeu_BaEn_1	89	94	PF01217	0.606
TRG_ENDOCYTIC_2	56	59	PF00928	0.731
TRG_ER_diArg_1	31	33	PF00400	0.513

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL34	Leptomonas seymouri	49%	71%
A4IA50	Leishmania infantum	98%	100%
E9B564	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q2S1	Leishmania major	95%	100%