Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X823_LEIDO

TriTrypDb:

LdBPK_342330.1 , LdCL_340031000

Length:

476

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3S7X823

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X823

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	265	267	PF00675	0.586
CLV_NRD_NRD_1	301	303	PF00675	0.566
CLV_NRD_NRD_1	463	465	PF00675	0.631
CLV_NRD_NRD_1	67	69	PF00675	0.330
CLV_NRD_NRD_1	92	94	PF00675	0.372
CLV_PCSK_FUR_1	461	465	PF00082	0.633
CLV_PCSK_KEX2_1	301	303	PF00082	0.566
CLV_PCSK_KEX2_1	457	459	PF00082	0.633
CLV_PCSK_KEX2_1	463	465	PF00082	0.631
CLV_PCSK_KEX2_1	67	69	PF00082	0.330
CLV_PCSK_KEX2_1	92	94	PF00082	0.372
CLV_PCSK_PC1ET2_1	457	459	PF00082	0.633
CLV_PCSK_SKI1_1	247	251	PF00082	0.590
CLV_PCSK_SKI1_1	270	274	PF00082	0.586
CLV_PCSK_SKI1_1	339	343	PF00082	0.552
CLV_PCSK_SKI1_1	354	358	PF00082	0.576
CLV_PCSK_SKI1_1	75	79	PF00082	0.357
DEG_SCF_FBW7_1	420	425	PF00400	0.379
DEG_SPOP_SBC_1	292	296	PF00917	0.403
DOC_CKS1_1	419	424	PF01111	0.380
DOC_MAPK_FxFP_2	383	386	PF00069	0.356
DOC_MAPK_gen_1	291	299	PF00069	0.397
DOC_MAPK_gen_1	301	310	PF00069	0.344
DOC_MAPK_gen_1	4	11	PF00069	0.502
DOC_MAPK_MEF2A_6	274	281	PF00069	0.384
DOC_MAPK_MEF2A_6	301	310	PF00069	0.344
DOC_MAPK_MEF2A_6	4	11	PF00069	0.502
DOC_PP1_RVXF_1	337	344	PF00149	0.352
DOC_PP2B_LxvP_1	78	81	PF13499	0.557
DOC_PP2B_PxIxI_1	276	282	PF00149	0.386
DOC_PP4_FxxP_1	369	372	PF00568	0.376
DOC_PP4_FxxP_1	383	386	PF00568	0.356
DOC_PP4_FxxP_1	76	79	PF00568	0.557
DOC_SPAK_OSR1_1	321	325	PF12202	0.324
DOC_USP7_MATH_1	153	157	PF00917	0.363
DOC_USP7_MATH_1	167	171	PF00917	0.376
DOC_USP7_MATH_1	179	183	PF00917	0.381
DOC_USP7_MATH_1	444	448	PF00917	0.422
DOC_USP7_UBL2_3	204	208	PF12436	0.409
DOC_USP7_UBL2_3	211	215	PF12436	0.399
DOC_WW_Pin1_4	237	242	PF00397	0.373
DOC_WW_Pin1_4	309	314	PF00397	0.350
DOC_WW_Pin1_4	367	372	PF00397	0.373
DOC_WW_Pin1_4	418	423	PF00397	0.377
DOC_WW_Pin1_4	425	430	PF00397	0.388
DOC_WW_Pin1_4	432	437	PF00397	0.403
DOC_WW_Pin1_4	462	467	PF00397	0.424
LIG_14-3-3_CanoR_1	145	151	PF00244	0.363
LIG_14-3-3_CanoR_1	291	299	PF00244	0.397
LIG_14-3-3_CanoR_1	360	366	PF00244	0.365
LIG_14-3-3_CanoR_1	437	444	PF00244	0.418
LIG_14-3-3_CanoR_1	6	12	PF00244	0.400
LIG_14-3-3_CanoR_1	67	76	PF00244	0.539
LIG_14-3-3_CanoR_1	95	100	PF00244	0.555
LIG_BRCT_BRCA1_1	295	299	PF00533	0.388
LIG_BRCT_BRCA1_1	381	385	PF00533	0.355
LIG_deltaCOP1_diTrp_1	139	147	PF00928	0.361
LIG_eIF4E_1	113	119	PF01652	0.199
LIG_eIF4E_1	13	19	PF01652	0.199
LIG_EVH1_1	78	82	PF00568	0.557
LIG_FHA_1	181	187	PF00498	0.379
LIG_FHA_1	193	199	PF00498	0.390
LIG_FHA_1	263	269	PF00498	0.382
LIG_FHA_1	271	277	PF00498	0.383
LIG_LIR_Apic_2	382	386	PF02991	0.358
LIG_LIR_Apic_2	418	422	PF02991	0.376
LIG_LIR_Gen_1	10	21	PF02991	0.199
LIG_LIR_Gen_1	146	153	PF02991	0.362
LIG_LIR_Gen_1	303	313	PF02991	0.340
LIG_LIR_Gen_1	378	388	PF02991	0.362
LIG_LIR_Gen_1	421	429	PF02991	0.383
LIG_LIR_Gen_1	51	61	PF02991	0.199
LIG_LIR_Nem_3	104	109	PF02991	0.199
LIG_LIR_Nem_3	146	150	PF02991	0.362
LIG_LIR_Nem_3	303	308	PF02991	0.333
LIG_LIR_Nem_3	373	377	PF02991	0.374
LIG_LIR_Nem_3	378	384	PF02991	0.360
LIG_LIR_Nem_3	387	391	PF02991	0.365
LIG_LIR_Nem_3	421	426	PF02991	0.382
LIG_LIR_Nem_3	51	57	PF02991	0.199
LIG_NRBOX	10	16	PF00104	0.199
LIG_NRBOX	51	57	PF00104	0.199
LIG_OCRL_FandH_1	105	117	PF00620	0.199
LIG_PCNA_yPIPBox_3	250	263	PF02747	0.381
LIG_PCNA_yPIPBox_3	463	476	PF02747	0.418
LIG_Pex14_1	419	423	PF04695	0.379
LIG_Pex14_2	379	383	PF04695	0.358
LIG_SH2_CRK	374	378	PF00017	0.375
LIG_SH2_SRC	365	368	PF00017	0.369
LIG_SH2_STAP1	365	369	PF00017	0.372
LIG_SH2_STAT5	113	116	PF00017	0.199
LIG_SH2_STAT5	13	16	PF00017	0.199
LIG_SH2_STAT5	305	308	PF00017	0.328
LIG_SH3_3	305	311	PF00018	0.335
LIG_SH3_3	76	82	PF00018	0.556
LIG_SUMO_SIM_anti_2	278	285	PF11976	0.388
LIG_SUMO_SIM_par_1	194	200	PF11976	0.392
LIG_SxIP_EBH_1	66	75	PF03271	0.535
LIG_TRAF2_1	197	200	PF00917	0.394
LIG_TRAF2_1	448	451	PF00917	0.433
LIG_TRFH_1	76	80	PF08558	0.557
LIG_WW_1	371	374	PF00397	0.374
MOD_CDK_SPK_2	432	437	PF00069	0.403
MOD_CDK_SPxK_1	462	468	PF00069	0.425
MOD_CDK_SPxxK_3	309	316	PF00069	0.354
MOD_CDK_SPxxK_3	425	432	PF00069	0.389
MOD_CK1_1	125	131	PF00069	0.371
MOD_CK1_1	160	166	PF00069	0.378
MOD_CK1_1	375	381	PF00069	0.367
MOD_CK1_1	418	424	PF00069	0.377
MOD_CK1_1	435	441	PF00069	0.412
MOD_CK1_1	462	468	PF00069	0.425
MOD_CK2_1	199	205	PF00069	0.400
MOD_CK2_1	297	303	PF00069	0.372
MOD_CK2_1	435	441	PF00069	0.412
MOD_CK2_1	444	450	PF00069	0.425
MOD_GlcNHglycan	159	162	PF01048	0.578
MOD_GlcNHglycan	446	449	PF01048	0.628
MOD_GSK3_1	153	160	PF00069	0.370
MOD_GSK3_1	293	300	PF00069	0.389
MOD_GSK3_1	375	382	PF00069	0.367
MOD_GSK3_1	418	425	PF00069	0.378
MOD_GSK3_1	63	70	PF00069	0.523
MOD_GSK3_1	83	90	PF00069	0.563
MOD_N-GLC_1	255	260	PF02516	0.581
MOD_NEK2_1	114	119	PF00069	0.199
MOD_NEK2_1	14	19	PF00069	0.199
MOD_NEK2_1	157	162	PF00069	0.378
MOD_NEK2_1	21	26	PF00069	0.199
MOD_NEK2_1	379	384	PF00069	0.358
MOD_NEK2_1	56	61	PF00069	0.199
MOD_NEK2_2	153	158	PF00069	0.366
MOD_PIKK_1	151	157	PF00454	0.363
MOD_PIKK_1	180	186	PF00454	0.379
MOD_PIKK_1	456	462	PF00454	0.434
MOD_PK_1	68	74	PF00069	0.534
MOD_PKA_1	67	73	PF00069	0.533
MOD_PKA_2	200	206	PF00069	0.402
MOD_PKA_2	292	298	PF00069	0.399
MOD_PKA_2	444	450	PF00069	0.425
MOD_PKA_2	67	73	PF00069	0.533
MOD_PKB_1	291	299	PF00069	0.397
MOD_PKB_1	93	101	PF00069	0.558
MOD_Plk_1	125	131	PF00069	0.371
MOD_Plk_1	386	392	PF00069	0.365
MOD_Plk_4	114	120	PF00069	0.199
MOD_Plk_4	14	20	PF00069	0.199
MOD_Plk_4	153	159	PF00069	0.369
MOD_Plk_4	255	261	PF00069	0.378
MOD_Plk_4	48	54	PF00069	0.199
MOD_Plk_4	56	62	PF00069	0.199
MOD_Plk_4	68	74	PF00069	0.534
MOD_ProDKin_1	237	243	PF00069	0.373
MOD_ProDKin_1	309	315	PF00069	0.353
MOD_ProDKin_1	367	373	PF00069	0.372
MOD_ProDKin_1	418	424	PF00069	0.377
MOD_ProDKin_1	425	431	PF00069	0.388
MOD_ProDKin_1	432	438	PF00069	0.404
MOD_ProDKin_1	462	468	PF00069	0.425
MOD_SUMO_rev_2	284	290	PF00179	0.398
TRG_DiLeu_BaEn_1	337	342	PF01217	0.354
TRG_DiLeu_BaEn_2	32	38	PF01217	0.303
TRG_ENDOCYTIC_2	13	16	PF00928	0.199
TRG_ENDOCYTIC_2	305	308	PF00928	0.328
TRG_ENDOCYTIC_2	374	377	PF00928	0.376
TRG_ER_diArg_1	290	293	PF00400	0.408
TRG_ER_diArg_1	397	400	PF00400	0.370
TRG_ER_diArg_1	4	7	PF00400	0.518
TRG_ER_diArg_1	461	464	PF00400	0.436
TRG_ER_diArg_1	67	69	PF00400	0.530
TRG_ER_diArg_1	91	93	PF00400	0.574