Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X7Y4_LEIDO

TriTrypDb:

LdBPK_342150.1 , LdCL_340029200 , LDHU3_34.3590

Length:

362

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X7Y4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X7Y4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	221	225	PF00656	0.715
CLV_C14_Caspase3-7	244	248	PF00656	0.691
CLV_C14_Caspase3-7	284	288	PF00656	0.653
CLV_NRD_NRD_1	297	299	PF00675	0.794
CLV_NRD_NRD_1	315	317	PF00675	0.824
CLV_NRD_NRD_1	43	45	PF00675	0.595
CLV_PCSK_KEX2_1	297	299	PF00082	0.680
CLV_PCSK_KEX2_1	314	316	PF00082	0.824
CLV_PCSK_KEX2_1	338	340	PF00082	0.639
CLV_PCSK_KEX2_1	43	45	PF00082	0.595
CLV_PCSK_PC1ET2_1	338	340	PF00082	0.592
CLV_PCSK_PC1ET2_1	43	45	PF00082	0.595
CLV_PCSK_PC7_1	293	299	PF00082	0.629
CLV_PCSK_SKI1_1	132	136	PF00082	0.587
CLV_PCSK_SKI1_1	16	20	PF00082	0.538
CLV_PCSK_SKI1_1	189	193	PF00082	0.530
CLV_PCSK_SKI1_1	338	342	PF00082	0.637
CLV_PCSK_SKI1_1	6	10	PF00082	0.629
DEG_Nend_UBRbox_3	1	3	PF02207	0.651
DEG_SPOP_SBC_1	307	311	PF00917	0.563
DOC_CKS1_1	7	12	PF01111	0.645
DOC_MAPK_gen_1	185	193	PF00069	0.599
DOC_MAPK_gen_1	297	304	PF00069	0.682
DOC_USP7_MATH_1	283	287	PF00917	0.648
DOC_USP7_MATH_1	34	38	PF00917	0.610
DOC_USP7_MATH_1	358	362	PF00917	0.535
DOC_USP7_MATH_1	48	52	PF00917	0.652
DOC_USP7_MATH_1	84	88	PF00917	0.586
DOC_WW_Pin1_4	30	35	PF00397	0.630
DOC_WW_Pin1_4	303	308	PF00397	0.586
DOC_WW_Pin1_4	6	11	PF00397	0.572
LIG_14-3-3_CanoR_1	100	106	PF00244	0.709
LIG_14-3-3_CanoR_1	167	177	PF00244	0.516
LIG_14-3-3_CanoR_1	195	201	PF00244	0.675
LIG_14-3-3_CanoR_1	28	34	PF00244	0.690
LIG_14-3-3_CanoR_1	297	301	PF00244	0.681
LIG_14-3-3_CanoR_1	62	67	PF00244	0.565
LIG_APCC_ABBAyCdc20_2	16	22	PF00400	0.673
LIG_BRCT_BRCA1_1	140	144	PF00533	0.738
LIG_FHA_1	117	123	PF00498	0.597
LIG_FHA_1	188	194	PF00498	0.558
LIG_FHA_1	331	337	PF00498	0.644
LIG_FHA_1	339	345	PF00498	0.583
LIG_FHA_2	197	203	PF00498	0.693
LIG_FHA_2	279	285	PF00498	0.670
LIG_LIR_Nem_3	133	138	PF02991	0.669
LIG_NRP_CendR_1	359	362	PF00754	0.633
LIG_SH2_SRC	252	255	PF00017	0.647
LIG_SH2_STAP1	252	256	PF00017	0.643
LIG_SH2_STAT3	198	201	PF00017	0.673
LIG_SH2_STAT5	198	201	PF00017	0.617
LIG_SH3_3	273	279	PF00018	0.641
LIG_SH3_3	302	308	PF00018	0.623
LIG_SH3_3	317	323	PF00018	0.584
LIG_SH3_3	352	358	PF00018	0.646
LIG_SH3_3	66	72	PF00018	0.603
LIG_TRAF2_1	199	202	PF00917	0.613
LIG_TRAF2_1	258	261	PF00917	0.686
MOD_CDK_SPK_2	30	35	PF00069	0.630
MOD_CDK_SPxxK_3	6	13	PF00069	0.597
MOD_CK1_1	106	112	PF00069	0.468
MOD_CK1_1	14	20	PF00069	0.589
MOD_CK1_1	152	158	PF00069	0.668
MOD_CK1_1	194	200	PF00069	0.676
MOD_CK1_1	303	309	PF00069	0.644
MOD_CK1_1	325	331	PF00069	0.687
MOD_CK1_1	76	82	PF00069	0.671
MOD_CK1_1	87	93	PF00069	0.606
MOD_CK1_1	95	101	PF00069	0.602
MOD_CK2_1	196	202	PF00069	0.672
MOD_CK2_1	220	226	PF00069	0.646
MOD_CK2_1	278	284	PF00069	0.636
MOD_CK2_1	285	291	PF00069	0.577
MOD_GlcNHglycan	140	143	PF01048	0.663
MOD_GlcNHglycan	151	154	PF01048	0.546
MOD_GlcNHglycan	253	257	PF01048	0.618
MOD_GlcNHglycan	273	276	PF01048	0.511
MOD_GlcNHglycan	324	327	PF01048	0.637
MOD_GlcNHglycan	36	39	PF01048	0.588
MOD_GlcNHglycan	97	100	PF01048	0.604
MOD_GSK3_1	187	194	PF00069	0.611
MOD_GSK3_1	196	203	PF00069	0.679
MOD_GSK3_1	218	225	PF00069	0.589
MOD_GSK3_1	230	237	PF00069	0.554
MOD_GSK3_1	252	259	PF00069	0.601
MOD_GSK3_1	267	274	PF00069	0.701
MOD_GSK3_1	296	303	PF00069	0.694
MOD_GSK3_1	30	37	PF00069	0.686
MOD_GSK3_1	322	329	PF00069	0.747
MOD_GSK3_1	43	50	PF00069	0.606
MOD_GSK3_1	60	67	PF00069	0.497
MOD_GSK3_1	72	79	PF00069	0.625
MOD_N-GLC_1	106	111	PF02516	0.652
MOD_N-GLC_1	79	84	PF02516	0.614
MOD_NEK2_1	101	106	PF00069	0.667
MOD_NEK2_1	122	127	PF00069	0.717
MOD_NEK2_1	191	196	PF00069	0.619
MOD_NEK2_1	200	205	PF00069	0.565
MOD_NEK2_1	232	237	PF00069	0.597
MOD_NEK2_1	296	301	PF00069	0.645
MOD_NEK2_1	60	65	PF00069	0.587
MOD_PIKK_1	168	174	PF00454	0.514
MOD_PIKK_1	267	273	PF00454	0.694
MOD_PIKK_1	87	93	PF00454	0.682
MOD_PKA_1	338	344	PF00069	0.616
MOD_PKA_1	43	49	PF00069	0.594
MOD_PKA_2	194	200	PF00069	0.654
MOD_PKA_2	296	302	PF00069	0.681
MOD_PKA_2	338	344	PF00069	0.616
MOD_PKA_2	43	49	PF00069	0.586
MOD_PKA_2	87	93	PF00069	0.682
MOD_PKB_1	185	193	PF00069	0.606
MOD_Plk_1	147	153	PF00069	0.645
MOD_Plk_1	187	193	PF00069	0.595
MOD_Plk_1	201	207	PF00069	0.603
MOD_Plk_1	218	224	PF00069	0.733
MOD_Plk_1	79	85	PF00069	0.616
MOD_Plk_2-3	218	224	PF00069	0.688
MOD_Plk_4	14	20	PF00069	0.657
MOD_Plk_4	300	306	PF00069	0.679
MOD_Plk_4	64	70	PF00069	0.656
MOD_ProDKin_1	30	36	PF00069	0.634
MOD_ProDKin_1	303	309	PF00069	0.587
MOD_ProDKin_1	6	12	PF00069	0.571
TRG_ER_diArg_1	184	187	PF00400	0.583
TRG_ER_diArg_1	296	298	PF00400	0.629
TRG_ER_diArg_1	313	316	PF00400	0.709
TRG_ER_diLys_1	357	362	PF00400	0.607
TRG_Pf-PMV_PEXEL_1	132	136	PF00026	0.615

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IAB5	Leptomonas seymouri	40%	100%
A4HAU9	Leishmania braziliensis	67%	100%
A4IAM0	Leishmania infantum	100%	100%
E9B524	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q2W2	Leishmania major	92%	100%