LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Coiled-coil domain-containing protein 52

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Coiled-coil domain-containing protein 52
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X7P7_LEIDO
TriTrypDb:
LdBPK_341420.1 * , LdCL_340020200 , LDHU3_34.2190
Length:
954

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X7P7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X7P7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 174 178 PF00656 0.565
CLV_C14_Caspase3-7 21 25 PF00656 0.618
CLV_C14_Caspase3-7 450 454 PF00656 0.427
CLV_C14_Caspase3-7 905 909 PF00656 0.607
CLV_NRD_NRD_1 13 15 PF00675 0.589
CLV_NRD_NRD_1 233 235 PF00675 0.556
CLV_NRD_NRD_1 327 329 PF00675 0.646
CLV_NRD_NRD_1 382 384 PF00675 0.581
CLV_NRD_NRD_1 670 672 PF00675 0.424
CLV_NRD_NRD_1 695 697 PF00675 0.530
CLV_NRD_NRD_1 723 725 PF00675 0.551
CLV_NRD_NRD_1 750 752 PF00675 0.676
CLV_NRD_NRD_1 799 801 PF00675 0.696
CLV_NRD_NRD_1 833 835 PF00675 0.628
CLV_NRD_NRD_1 886 888 PF00675 0.712
CLV_NRD_NRD_1 90 92 PF00675 0.637
CLV_PCSK_FUR_1 693 697 PF00082 0.524
CLV_PCSK_KEX2_1 13 15 PF00082 0.566
CLV_PCSK_KEX2_1 327 329 PF00082 0.713
CLV_PCSK_KEX2_1 382 384 PF00082 0.592
CLV_PCSK_KEX2_1 396 398 PF00082 0.582
CLV_PCSK_KEX2_1 695 697 PF00082 0.530
CLV_PCSK_KEX2_1 723 725 PF00082 0.551
CLV_PCSK_KEX2_1 750 752 PF00082 0.633
CLV_PCSK_KEX2_1 833 835 PF00082 0.628
CLV_PCSK_KEX2_1 88 90 PF00082 0.729
CLV_PCSK_KEX2_1 912 914 PF00082 0.726
CLV_PCSK_PC1ET2_1 396 398 PF00082 0.661
CLV_PCSK_PC1ET2_1 88 90 PF00082 0.697
CLV_PCSK_PC1ET2_1 912 914 PF00082 0.726
CLV_PCSK_SKI1_1 144 148 PF00082 0.480
CLV_PCSK_SKI1_1 449 453 PF00082 0.434
CLV_PCSK_SKI1_1 614 618 PF00082 0.399
CLV_PCSK_SKI1_1 81 85 PF00082 0.625
CLV_PCSK_SKI1_1 922 926 PF00082 0.577
CLV_PCSK_SKI1_1 947 951 PF00082 0.553
DEG_APCC_DBOX_1 305 313 PF00400 0.572
DEG_APCC_KENBOX_2 532 536 PF00400 0.583
DEG_Nend_UBRbox_2 1 3 PF02207 0.649
DEG_SPOP_SBC_1 855 859 PF00917 0.576
DOC_ANK_TNKS_1 736 743 PF00023 0.598
DOC_CKS1_1 725 730 PF01111 0.470
DOC_CYCLIN_yCln2_LP_2 601 607 PF00134 0.564
DOC_MAPK_gen_1 925 935 PF00069 0.682
DOC_MAPK_gen_1 945 953 PF00069 0.437
DOC_MAPK_MEF2A_6 352 359 PF00069 0.568
DOC_MAPK_MEF2A_6 419 427 PF00069 0.387
DOC_MAPK_MEF2A_6 789 797 PF00069 0.562
DOC_MIT_MIM_1 688 697 PF04212 0.529
DOC_PP1_RVXF_1 166 173 PF00149 0.508
DOC_PP1_RVXF_1 567 573 PF00149 0.497
DOC_PP2B_LxvP_1 601 604 PF13499 0.623
DOC_PP2B_LxvP_1 879 882 PF13499 0.670
DOC_USP7_MATH_1 122 126 PF00917 0.488
DOC_USP7_MATH_1 215 219 PF00917 0.525
DOC_USP7_MATH_1 347 351 PF00917 0.646
DOC_USP7_MATH_1 36 40 PF00917 0.675
DOC_USP7_MATH_1 447 451 PF00917 0.569
DOC_USP7_MATH_1 45 49 PF00917 0.631
DOC_USP7_MATH_1 539 543 PF00917 0.448
DOC_USP7_MATH_1 581 585 PF00917 0.627
DOC_USP7_MATH_1 69 73 PF00917 0.682
DOC_USP7_MATH_1 769 773 PF00917 0.652
DOC_USP7_MATH_1 775 779 PF00917 0.600
DOC_USP7_MATH_1 844 848 PF00917 0.573
DOC_WW_Pin1_4 26 31 PF00397 0.532
DOC_WW_Pin1_4 273 278 PF00397 0.589
DOC_WW_Pin1_4 334 339 PF00397 0.604
DOC_WW_Pin1_4 343 348 PF00397 0.620
DOC_WW_Pin1_4 372 377 PF00397 0.796
DOC_WW_Pin1_4 6 11 PF00397 0.607
DOC_WW_Pin1_4 724 729 PF00397 0.454
DOC_WW_Pin1_4 735 740 PF00397 0.564
DOC_WW_Pin1_4 74 79 PF00397 0.611
DOC_WW_Pin1_4 783 788 PF00397 0.727
DOC_WW_Pin1_4 82 87 PF00397 0.636
DOC_WW_Pin1_4 832 837 PF00397 0.602
DOC_WW_Pin1_4 856 861 PF00397 0.603
DOC_WW_Pin1_4 898 903 PF00397 0.583
LIG_14-3-3_CanoR_1 13 19 PF00244 0.566
LIG_14-3-3_CanoR_1 189 194 PF00244 0.511
LIG_14-3-3_CanoR_1 225 233 PF00244 0.515
LIG_14-3-3_CanoR_1 311 317 PF00244 0.589
LIG_14-3-3_CanoR_1 382 390 PF00244 0.685
LIG_14-3-3_CanoR_1 578 588 PF00244 0.520
LIG_14-3-3_CanoR_1 623 627 PF00244 0.528
LIG_14-3-3_CanoR_1 662 670 PF00244 0.495
LIG_14-3-3_CanoR_1 74 78 PF00244 0.627
LIG_14-3-3_CanoR_1 81 86 PF00244 0.597
LIG_14-3-3_CanoR_1 90 100 PF00244 0.677
LIG_APCC_ABBA_1 932 937 PF00400 0.536
LIG_BIR_III_4 421 425 PF00653 0.526
LIG_CaM_IQ_9 425 441 PF13499 0.533
LIG_CaM_IQ_9 664 680 PF13499 0.544
LIG_DLG_GKlike_1 189 196 PF00625 0.490
LIG_EH1_1 184 192 PF00400 0.494
LIG_EVH1_1 879 883 PF00568 0.621
LIG_FHA_1 235 241 PF00498 0.552
LIG_FHA_1 408 414 PF00498 0.583
LIG_FHA_1 630 636 PF00498 0.469
LIG_FHA_1 661 667 PF00498 0.495
LIG_FHA_1 833 839 PF00498 0.753
LIG_FHA_2 529 535 PF00498 0.576
LIG_FHA_2 617 623 PF00498 0.458
LIG_FHA_2 903 909 PF00498 0.646
LIG_GBD_Chelix_1 483 491 PF00786 0.454
LIG_LIR_Gen_1 192 197 PF02991 0.516
LIG_LIR_Gen_1 525 530 PF02991 0.474
LIG_LIR_Gen_1 702 712 PF02991 0.449
LIG_LIR_Gen_1 948 954 PF02991 0.584
LIG_LIR_Nem_3 192 196 PF02991 0.520
LIG_LIR_Nem_3 525 529 PF02991 0.484
LIG_LIR_Nem_3 702 707 PF02991 0.462
LIG_LIR_Nem_3 948 953 PF02991 0.530
LIG_MYND_3 740 744 PF01753 0.524
LIG_PCNA_yPIPBox_3 500 510 PF02747 0.490
LIG_REV1ctd_RIR_1 731 738 PF16727 0.545
LIG_SH2_CRK 526 530 PF00017 0.471
LIG_SH2_PTP2 193 196 PF00017 0.515
LIG_SH2_SRC 180 183 PF00017 0.538
LIG_SH2_STAP1 526 530 PF00017 0.465
LIG_SH2_STAP1 711 715 PF00017 0.519
LIG_SH2_STAT5 149 152 PF00017 0.548
LIG_SH2_STAT5 180 183 PF00017 0.539
LIG_SH2_STAT5 193 196 PF00017 0.598
LIG_SH2_STAT5 412 415 PF00017 0.597
LIG_SH2_STAT5 6 9 PF00017 0.616
LIG_SH2_STAT5 726 729 PF00017 0.535
LIG_SH2_STAT5 794 797 PF00017 0.588
LIG_SH2_STAT5 830 833 PF00017 0.606
LIG_SH2_STAT5 893 896 PF00017 0.571
LIG_SH3_1 784 790 PF00018 0.636
LIG_SH3_2 882 887 PF14604 0.581
LIG_SH3_3 24 30 PF00018 0.652
LIG_SH3_3 288 294 PF00018 0.624
LIG_SH3_3 373 379 PF00018 0.690
LIG_SH3_3 585 591 PF00018 0.551
LIG_SH3_3 597 603 PF00018 0.725
LIG_SH3_3 644 650 PF00018 0.415
LIG_SH3_3 784 790 PF00018 0.663
LIG_SH3_3 877 883 PF00018 0.606
LIG_Sin3_3 712 719 PF02671 0.439
LIG_TRAF2_1 164 167 PF00917 0.480
LIG_TYR_ITIM 191 196 PF00017 0.513
LIG_WRC_WIRS_1 617 622 PF05994 0.454
LIG_WW_1 602 605 PF00397 0.574
LIG_WW_3 859 863 PF00397 0.768
LIG_WW_3 884 888 PF00397 0.572
MOD_CDC14_SPxK_1 276 279 PF00782 0.604
MOD_CDC14_SPxK_1 786 789 PF00782 0.607
MOD_CDC14_SPxK_1 85 88 PF00782 0.570
MOD_CDK_SPK_2 6 11 PF00069 0.607
MOD_CDK_SPxK_1 273 279 PF00069 0.604
MOD_CDK_SPxK_1 783 789 PF00069 0.614
MOD_CDK_SPxK_1 82 88 PF00069 0.635
MOD_CDK_SPxK_1 856 862 PF00069 0.553
MOD_CDK_SPxxK_3 26 33 PF00069 0.573
MOD_CDK_SPxxK_3 375 382 PF00069 0.633
MOD_CDK_SPxxK_3 6 13 PF00069 0.571
MOD_CDK_SPxxK_3 74 81 PF00069 0.611
MOD_CDK_SPxxK_3 82 89 PF00069 0.561
MOD_CK1_1 116 122 PF00069 0.530
MOD_CK1_1 265 271 PF00069 0.782
MOD_CK1_1 330 336 PF00069 0.689
MOD_CK1_1 337 343 PF00069 0.665
MOD_CK1_1 367 373 PF00069 0.701
MOD_CK1_1 375 381 PF00069 0.646
MOD_CK1_1 528 534 PF00069 0.570
MOD_CK1_1 584 590 PF00069 0.641
MOD_CK1_1 72 78 PF00069 0.597
MOD_CK1_1 796 802 PF00069 0.615
MOD_CK1_1 854 860 PF00069 0.746
MOD_CK1_1 870 876 PF00069 0.593
MOD_CK2_1 161 167 PF00069 0.546
MOD_CK2_1 312 318 PF00069 0.528
MOD_CK2_1 347 353 PF00069 0.664
MOD_CK2_1 528 534 PF00069 0.566
MOD_CK2_1 539 545 PF00069 0.452
MOD_CK2_1 584 590 PF00069 0.717
MOD_CK2_1 616 622 PF00069 0.515
MOD_CK2_1 767 773 PF00069 0.698
MOD_CK2_1 775 781 PF00069 0.593
MOD_CK2_1 897 903 PF00069 0.628
MOD_Cter_Amidation 103 106 PF01082 0.701
MOD_Cter_Amidation 11 14 PF01082 0.573
MOD_DYRK1A_RPxSP_1 74 78 PF00069 0.611
MOD_GlcNHglycan 107 110 PF01048 0.691
MOD_GlcNHglycan 136 139 PF01048 0.538
MOD_GlcNHglycan 163 166 PF01048 0.545
MOD_GlcNHglycan 249 252 PF01048 0.683
MOD_GlcNHglycan 258 261 PF01048 0.731
MOD_GlcNHglycan 264 267 PF01048 0.620
MOD_GlcNHglycan 329 332 PF01048 0.755
MOD_GlcNHglycan 363 369 PF01048 0.588
MOD_GlcNHglycan 38 41 PF01048 0.692
MOD_GlcNHglycan 47 50 PF01048 0.608
MOD_GlcNHglycan 478 481 PF01048 0.442
MOD_GlcNHglycan 512 515 PF01048 0.447
MOD_GlcNHglycan 537 540 PF01048 0.568
MOD_GlcNHglycan 583 586 PF01048 0.593
MOD_GlcNHglycan 681 684 PF01048 0.591
MOD_GlcNHglycan 744 747 PF01048 0.631
MOD_GlcNHglycan 847 850 PF01048 0.682
MOD_GlcNHglycan 853 856 PF01048 0.655
MOD_GlcNHglycan 866 870 PF01048 0.576
MOD_GlcNHglycan 875 878 PF01048 0.813
MOD_GSK3_1 122 129 PF00069 0.678
MOD_GSK3_1 2 9 PF00069 0.692
MOD_GSK3_1 22 29 PF00069 0.516
MOD_GSK3_1 224 231 PF00069 0.582
MOD_GSK3_1 312 319 PF00069 0.679
MOD_GSK3_1 327 334 PF00069 0.614
MOD_GSK3_1 343 350 PF00069 0.665
MOD_GSK3_1 36 43 PF00069 0.588
MOD_GSK3_1 364 371 PF00069 0.802
MOD_GSK3_1 378 385 PF00069 0.556
MOD_GSK3_1 50 57 PF00069 0.566
MOD_GSK3_1 524 531 PF00069 0.506
MOD_GSK3_1 535 542 PF00069 0.459
MOD_GSK3_1 679 686 PF00069 0.530
MOD_GSK3_1 68 75 PF00069 0.563
MOD_GSK3_1 742 749 PF00069 0.641
MOD_GSK3_1 775 782 PF00069 0.698
MOD_GSK3_1 851 858 PF00069 0.635
MOD_GSK3_1 889 896 PF00069 0.754
MOD_GSK3_1 897 904 PF00069 0.632
MOD_N-GLC_1 126 131 PF02516 0.446
MOD_N-GLC_1 134 139 PF02516 0.501
MOD_N-GLC_1 343 348 PF02516 0.628
MOD_N-GLC_1 397 402 PF02516 0.601
MOD_NEK2_1 1 6 PF00069 0.591
MOD_NEK2_1 113 118 PF00069 0.509
MOD_NEK2_1 131 136 PF00069 0.395
MOD_NEK2_1 196 201 PF00069 0.515
MOD_NEK2_1 247 252 PF00069 0.545
MOD_NEK2_1 296 301 PF00069 0.638
MOD_NEK2_1 466 471 PF00069 0.452
MOD_NEK2_1 645 650 PF00069 0.517
MOD_NEK2_1 660 665 PF00069 0.450
MOD_NEK2_1 679 684 PF00069 0.395
MOD_NEK2_1 733 738 PF00069 0.609
MOD_NEK2_1 851 856 PF00069 0.640
MOD_NEK2_1 867 872 PF00069 0.521
MOD_NEK2_2 69 74 PF00069 0.597
MOD_PIKK_1 159 165 PF00454 0.496
MOD_PIKK_1 228 234 PF00454 0.519
MOD_PIKK_1 296 302 PF00454 0.605
MOD_PIKK_1 337 343 PF00454 0.682
MOD_PIKK_1 345 351 PF00454 0.653
MOD_PIKK_1 368 374 PF00454 0.667
MOD_PIKK_1 407 413 PF00454 0.513
MOD_PIKK_1 52 58 PF00454 0.642
MOD_PIKK_1 539 545 PF00454 0.468
MOD_PIKK_1 914 920 PF00454 0.645
MOD_PKA_1 105 111 PF00069 0.520
MOD_PKA_1 13 19 PF00069 0.566
MOD_PKA_1 234 240 PF00069 0.577
MOD_PKA_1 327 333 PF00069 0.758
MOD_PKA_1 382 388 PF00069 0.574
MOD_PKA_2 12 18 PF00069 0.588
MOD_PKA_2 224 230 PF00069 0.499
MOD_PKA_2 296 302 PF00069 0.577
MOD_PKA_2 327 333 PF00069 0.672
MOD_PKA_2 382 388 PF00069 0.618
MOD_PKA_2 45 51 PF00069 0.627
MOD_PKA_2 466 472 PF00069 0.449
MOD_PKA_2 61 67 PF00069 0.562
MOD_PKA_2 622 628 PF00069 0.528
MOD_PKA_2 661 667 PF00069 0.491
MOD_PKA_2 73 79 PF00069 0.577
MOD_PKB_1 66 74 PF00069 0.576
MOD_PKB_1 89 97 PF00069 0.569
MOD_Plk_1 1 7 PF00069 0.610
MOD_Plk_1 126 132 PF00069 0.476
MOD_Plk_1 176 182 PF00069 0.576
MOD_Plk_1 397 403 PF00069 0.648
MOD_Plk_1 407 413 PF00069 0.487
MOD_Plk_1 524 530 PF00069 0.464
MOD_Plk_4 126 132 PF00069 0.516
MOD_Plk_4 171 177 PF00069 0.527
MOD_Plk_4 189 195 PF00069 0.380
MOD_Plk_4 312 318 PF00069 0.509
MOD_Plk_4 447 453 PF00069 0.483
MOD_Plk_4 616 622 PF00069 0.434
MOD_Plk_4 793 799 PF00069 0.675
MOD_Plk_4 889 895 PF00069 0.562
MOD_ProDKin_1 26 32 PF00069 0.533
MOD_ProDKin_1 273 279 PF00069 0.589
MOD_ProDKin_1 334 340 PF00069 0.604
MOD_ProDKin_1 343 349 PF00069 0.619
MOD_ProDKin_1 372 378 PF00069 0.795
MOD_ProDKin_1 6 12 PF00069 0.606
MOD_ProDKin_1 724 730 PF00069 0.457
MOD_ProDKin_1 735 741 PF00069 0.566
MOD_ProDKin_1 74 80 PF00069 0.606
MOD_ProDKin_1 783 789 PF00069 0.726
MOD_ProDKin_1 82 88 PF00069 0.636
MOD_ProDKin_1 832 838 PF00069 0.604
MOD_ProDKin_1 856 862 PF00069 0.607
MOD_ProDKin_1 898 904 PF00069 0.587
MOD_SUMO_for_1 111 114 PF00179 0.552
MOD_SUMO_for_1 924 927 PF00179 0.594
MOD_SUMO_rev_2 21 27 PF00179 0.612
TRG_DiLeu_BaEn_1 186 191 PF01217 0.494
TRG_ENDOCYTIC_2 193 196 PF00928 0.648
TRG_ENDOCYTIC_2 526 529 PF00928 0.469
TRG_ENDOCYTIC_2 794 797 PF00928 0.547
TRG_ER_diArg_1 100 103 PF00400 0.646
TRG_ER_diArg_1 327 329 PF00400 0.676
TRG_ER_diArg_1 692 695 PF00400 0.567
TRG_ER_diArg_1 750 752 PF00400 0.676
TRG_ER_diArg_1 805 808 PF00400 0.658
TRG_ER_diArg_1 89 91 PF00400 0.617
TRG_NES_CRM1_1 186 198 PF08389 0.489
TRG_NES_CRM1_1 415 429 PF08389 0.443
TRG_NES_CRM1_1 485 499 PF08389 0.507
TRG_NLS_MonoCore_2 87 92 PF00514 0.565
TRG_NLS_MonoExtN_4 86 92 PF00514 0.559
TRG_Pf-PMV_PEXEL_1 671 675 PF00026 0.419
TRG_Pf-PMV_PEXEL_1 695 699 PF00026 0.489
TRG_Pf-PMV_PEXEL_1 713 718 PF00026 0.360

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PC52 Leptomonas seymouri 39% 100%
A4HAP8 Leishmania braziliensis 62% 97%
A4I9U4 Leishmania infantum 99% 100%
E9B4V5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
Q4Q371 Leishmania major 90% 99%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS