ATP-dependent RNA helicase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7X7P0_LEIDO

TriTrypDb:

LdBPK_341290.1 , LdCL_340018900 , LDHU3_34.2020

Length:

1523

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 23
NetGPI	no	yes: 0, no: 23

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0020023	kinetoplast	2	2
GO:0031019	mitochondrial mRNA editing complex	3	1
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0043233	organelle lumen	3	2
GO:0045293	mRNA editing complex	3	1
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0098798	mitochondrial protein-containing complex	2	1
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	2
GO:1902494	catalytic complex	2	1

Expansion

Sequence features

A0A3S7X7P0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009451	RNA modification	5	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009893	positive regulation of metabolic process	4	1
GO:0009894	regulation of catabolic process	4	1
GO:0009895	negative regulation of catabolic process	5	1
GO:0009987	cellular process	1	1
GO:0010468	regulation of gene expression	5	1
GO:0010604	positive regulation of macromolecule metabolic process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010608	post-transcriptional regulation of gene expression	6	1
GO:0010628	positive regulation of gene expression	6	1
GO:0016070	RNA metabolic process	5	1
GO:0016071	mRNA metabolic process	6	1
GO:0016553	base conversion or substitution editing	6	1
GO:0016554	cytidine to uridine editing	7	1
GO:0016556	mRNA modification	6	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031329	regulation of cellular catabolic process	5	1
GO:0031330	negative regulation of cellular catabolic process	6	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0043412	macromolecule modification	4	1
GO:0043487	regulation of RNA stability	3	1
GO:0043488	regulation of mRNA stability	4	1
GO:0043489	RNA stabilization	4	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0048255	mRNA stabilization	5	1
GO:0048518	positive regulation of biological process	3	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051252	regulation of RNA metabolic process	5	1
GO:0051253	negative regulation of RNA metabolic process	6	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0061013	regulation of mRNA catabolic process	6	1
GO:0065007	biological regulation	1	1
GO:0065008	regulation of biological quality	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1902369	negative regulation of RNA catabolic process	7	1
GO:1902373	negative regulation of mRNA catabolic process	7	1
GO:1903311	regulation of mRNA metabolic process	6	1
GO:1903312	negative regulation of mRNA metabolic process	7	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	24
GO:0003676	nucleic acid binding	3	23
GO:0003824	catalytic activity	1	24
GO:0004386	helicase activity	2	24
GO:0005488	binding	1	24
GO:0005524	ATP binding	5	24
GO:0016787	hydrolase activity	2	15
GO:0017076	purine nucleotide binding	4	24
GO:0030554	adenyl nucleotide binding	5	24
GO:0032553	ribonucleotide binding	3	24
GO:0032555	purine ribonucleotide binding	4	24
GO:0032559	adenyl ribonucleotide binding	5	24
GO:0035639	purine ribonucleoside triphosphate binding	4	24
GO:0036094	small molecule binding	2	24
GO:0043167	ion binding	2	24
GO:0043168	anion binding	3	24
GO:0097159	organic cyclic compound binding	2	24
GO:0097367	carbohydrate derivative binding	2	24
GO:0140640	catalytic activity, acting on a nucleic acid	2	24
GO:0140657	ATP-dependent activity	1	24
GO:1901265	nucleoside phosphate binding	3	24
GO:1901363	heterocyclic compound binding	2	24
GO:0003723	RNA binding	4	12
GO:0003724	RNA helicase activity	3	1
GO:0003729	mRNA binding	5	1
GO:0008186	ATP-dependent activity, acting on RNA	2	1
GO:0034458	3'-5' RNA helicase activity	4	1
GO:0140098	catalytic activity, acting on RNA	3	1
GO:0008270	zinc ion binding	6	3
GO:0043169	cation binding	3	3
GO:0046872	metal ion binding	4	3
GO:0046914	transition metal ion binding	5	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1141	1145	PF00656	0.633
CLV_C14_Caspase3-7	1179	1183	PF00656	0.459
CLV_C14_Caspase3-7	123	127	PF00656	0.503
CLV_C14_Caspase3-7	1468	1472	PF00656	0.351
CLV_C14_Caspase3-7	183	187	PF00656	0.409
CLV_C14_Caspase3-7	424	428	PF00656	0.432
CLV_C14_Caspase3-7	800	804	PF00656	0.437
CLV_C14_Caspase3-7	896	900	PF00656	0.382
CLV_C14_Caspase3-7	990	994	PF00656	0.414
CLV_NRD_NRD_1	1065	1067	PF00675	0.428
CLV_NRD_NRD_1	1250	1252	PF00675	0.541
CLV_NRD_NRD_1	1272	1274	PF00675	0.485
CLV_NRD_NRD_1	1331	1333	PF00675	0.263
CLV_NRD_NRD_1	1418	1420	PF00675	0.450
CLV_NRD_NRD_1	165	167	PF00675	0.595
CLV_NRD_NRD_1	258	260	PF00675	0.536
CLV_NRD_NRD_1	290	292	PF00675	0.405
CLV_NRD_NRD_1	470	472	PF00675	0.491
CLV_NRD_NRD_1	482	484	PF00675	0.448
CLV_NRD_NRD_1	544	546	PF00675	0.278
CLV_NRD_NRD_1	59	61	PF00675	0.493
CLV_NRD_NRD_1	728	730	PF00675	0.565
CLV_NRD_NRD_1	923	925	PF00675	0.260
CLV_PCSK_FUR_1	1066	1070	PF00082	0.364
CLV_PCSK_FUR_1	255	259	PF00082	0.523
CLV_PCSK_KEX2_1	1068	1070	PF00082	0.430
CLV_PCSK_KEX2_1	1272	1274	PF00082	0.485
CLV_PCSK_KEX2_1	1331	1333	PF00082	0.263
CLV_PCSK_KEX2_1	1418	1420	PF00082	0.450
CLV_PCSK_KEX2_1	165	167	PF00082	0.601
CLV_PCSK_KEX2_1	169	171	PF00082	0.587
CLV_PCSK_KEX2_1	226	228	PF00082	0.445
CLV_PCSK_KEX2_1	257	259	PF00082	0.538
CLV_PCSK_KEX2_1	366	368	PF00082	0.299
CLV_PCSK_KEX2_1	470	472	PF00082	0.500
CLV_PCSK_KEX2_1	482	484	PF00082	0.372
CLV_PCSK_KEX2_1	544	546	PF00082	0.278
CLV_PCSK_KEX2_1	728	730	PF00082	0.602
CLV_PCSK_PC1ET2_1	1068	1070	PF00082	0.428
CLV_PCSK_PC1ET2_1	169	171	PF00082	0.385
CLV_PCSK_PC1ET2_1	226	228	PF00082	0.544
CLV_PCSK_PC1ET2_1	366	368	PF00082	0.299
CLV_PCSK_PC7_1	165	171	PF00082	0.382
CLV_PCSK_SKI1_1	1029	1033	PF00082	0.358
CLV_PCSK_SKI1_1	1069	1073	PF00082	0.436
CLV_PCSK_SKI1_1	1121	1125	PF00082	0.310
CLV_PCSK_SKI1_1	1264	1268	PF00082	0.523
CLV_PCSK_SKI1_1	1297	1301	PF00082	0.555
CLV_PCSK_SKI1_1	1332	1336	PF00082	0.333
CLV_PCSK_SKI1_1	1418	1422	PF00082	0.445
CLV_PCSK_SKI1_1	198	202	PF00082	0.554
CLV_PCSK_SKI1_1	223	227	PF00082	0.502
CLV_PCSK_SKI1_1	32	36	PF00082	0.406
CLV_PCSK_SKI1_1	404	408	PF00082	0.645
CLV_PCSK_SKI1_1	442	446	PF00082	0.532
CLV_PCSK_SKI1_1	51	55	PF00082	0.623
CLV_PCSK_SKI1_1	579	583	PF00082	0.298
CLV_PCSK_SKI1_1	60	64	PF00082	0.473
CLV_PCSK_SKI1_1	625	629	PF00082	0.274
CLV_PCSK_SKI1_1	635	639	PF00082	0.283
CLV_PCSK_SKI1_1	729	733	PF00082	0.501
CLV_PCSK_SKI1_1	758	762	PF00082	0.239
CLV_PCSK_SKI1_1	768	772	PF00082	0.262
CLV_PCSK_SKI1_1	820	824	PF00082	0.264
CLV_PCSK_SKI1_1	938	942	PF00082	0.447
CLV_Separin_Metazoa	148	152	PF03568	0.685
CLV_Separin_Metazoa	162	166	PF03568	0.485
CLV_Separin_Metazoa	997	1001	PF03568	0.416
DEG_APCC_DBOX_1	1331	1339	PF00400	0.428
DEG_APCC_DBOX_1	957	965	PF00400	0.354
DEG_Nend_Nbox_1	1	3	PF02207	0.490
DEG_SCF_FBW7_1	306	311	PF00400	0.599
DEG_SCF_FBW7_2	1011	1016	PF00400	0.540
DEG_SCF_FBW7_2	1420	1427	PF00400	0.249
DEG_SCF_SKP2-CKS1_1	704	711	PF00560	0.451
DEG_SPOP_SBC_1	1304	1308	PF00917	0.429
DEG_SPOP_SBC_1	869	873	PF00917	0.403
DOC_ANK_TNKS_1	246	253	PF00023	0.487
DOC_CKS1_1	110	115	PF01111	0.681
DOC_CKS1_1	1421	1426	PF01111	0.262
DOC_CYCLIN_RxL_1	1066	1076	PF00134	0.425
DOC_CYCLIN_RxL_1	1415	1423	PF00134	0.234
DOC_CYCLIN_RxL_1	60	74	PF00134	0.514
DOC_CYCLIN_RxL_1	622	632	PF00134	0.448
DOC_MAPK_gen_1	1246	1255	PF00069	0.509
DOC_MAPK_gen_1	470	476	PF00069	0.507
DOC_MAPK_gen_1	60	70	PF00069	0.466
DOC_MAPK_gen_1	630	638	PF00069	0.492
DOC_MAPK_HePTP_8	1416	1428	PF00069	0.333
DOC_MAPK_MEF2A_6	1419	1428	PF00069	0.336
DOC_MAPK_MEF2A_6	32	39	PF00069	0.496
DOC_MAPK_MEF2A_6	630	638	PF00069	0.479
DOC_MAPK_MEF2A_6	958	966	PF00069	0.288
DOC_MAPK_NFAT4_5	32	40	PF00069	0.545
DOC_PP1_RVXF_1	64	71	PF00149	0.538
DOC_PP2B_LxvP_1	1234	1237	PF13499	0.532
DOC_PP2B_LxvP_1	35	38	PF13499	0.485
DOC_PP2B_LxvP_1	715	718	PF13499	0.584
DOC_PP2B_LxvP_1	984	987	PF13499	0.602
DOC_PP4_FxxP_1	15	18	PF00568	0.758
DOC_PP4_FxxP_1	685	688	PF00568	0.447
DOC_PP4_FxxP_1	983	986	PF00568	0.468
DOC_USP7_MATH_1	1168	1172	PF00917	0.602
DOC_USP7_MATH_1	1176	1180	PF00917	0.625
DOC_USP7_MATH_1	1190	1194	PF00917	0.660
DOC_USP7_MATH_1	1240	1244	PF00917	0.607
DOC_USP7_MATH_1	1266	1270	PF00917	0.533
DOC_USP7_MATH_1	1304	1308	PF00917	0.429
DOC_USP7_MATH_1	1351	1355	PF00917	0.451
DOC_USP7_MATH_1	18	22	PF00917	0.726
DOC_USP7_MATH_1	278	282	PF00917	0.621
DOC_USP7_MATH_1	377	381	PF00917	0.511
DOC_USP7_MATH_1	481	485	PF00917	0.443
DOC_USP7_MATH_1	692	696	PF00917	0.549
DOC_USP7_MATH_1	709	713	PF00917	0.541
DOC_USP7_MATH_1	788	792	PF00917	0.583
DOC_USP7_MATH_1	813	817	PF00917	0.567
DOC_USP7_MATH_1	869	873	PF00917	0.567
DOC_USP7_MATH_1	87	91	PF00917	0.489
DOC_USP7_UBL2_3	707	711	PF12436	0.443
DOC_WW_Pin1_4	1009	1014	PF00397	0.449
DOC_WW_Pin1_4	109	114	PF00397	0.603
DOC_WW_Pin1_4	1128	1133	PF00397	0.566
DOC_WW_Pin1_4	1306	1311	PF00397	0.554
DOC_WW_Pin1_4	1420	1425	PF00397	0.282
DOC_WW_Pin1_4	1430	1435	PF00397	0.470
DOC_WW_Pin1_4	1444	1449	PF00397	0.549
DOC_WW_Pin1_4	304	309	PF00397	0.518
DOC_WW_Pin1_4	379	384	PF00397	0.568
DOC_WW_Pin1_4	653	658	PF00397	0.460
DOC_WW_Pin1_4	684	689	PF00397	0.429
DOC_WW_Pin1_4	705	710	PF00397	0.656
DOC_WW_Pin1_4	83	88	PF00397	0.650
DOC_WW_Pin1_4	872	877	PF00397	0.577
DOC_WW_Pin1_4	92	97	PF00397	0.548
LIG_14-3-3_CanoR_1	1211	1215	PF00244	0.495
LIG_14-3-3_CanoR_1	1377	1381	PF00244	0.366
LIG_14-3-3_CanoR_1	1387	1391	PF00244	0.346
LIG_14-3-3_CanoR_1	1405	1413	PF00244	0.599
LIG_14-3-3_CanoR_1	329	335	PF00244	0.536
LIG_14-3-3_CanoR_1	437	445	PF00244	0.528
LIG_14-3-3_CanoR_1	446	452	PF00244	0.467
LIG_14-3-3_CanoR_1	482	487	PF00244	0.380
LIG_14-3-3_CanoR_1	544	551	PF00244	0.460
LIG_14-3-3_CanoR_1	559	564	PF00244	0.451
LIG_14-3-3_CanoR_1	579	584	PF00244	0.475
LIG_14-3-3_CanoR_1	854	860	PF00244	0.489
LIG_14-3-3_CanoR_1	927	937	PF00244	0.562
LIG_Actin_WH2_2	1095	1113	PF00022	0.460
LIG_Actin_WH2_2	1450	1467	PF00022	0.373
LIG_Actin_WH2_2	18	34	PF00022	0.456
LIG_Actin_WH2_2	388	406	PF00022	0.564
LIG_Actin_WH2_2	620	637	PF00022	0.503
LIG_AP2alpha_1	1321	1325	PF02296	0.445
LIG_APCC_ABBA_1	1318	1323	PF00400	0.423
LIG_APCC_ABBA_1	1371	1376	PF00400	0.318
LIG_BIR_III_2	1147	1151	PF00653	0.392
LIG_BIR_III_4	243	247	PF00653	0.535
LIG_BRCT_BRCA1_1	686	690	PF00533	0.342
LIG_BRCT_BRCA1_1	874	878	PF00533	0.404
LIG_CaM_IQ_9	919	934	PF13499	0.437
LIG_CaM_NSCaTE_8	1344	1351	PF13499	0.352
LIG_Clathr_ClatBox_1	1483	1487	PF01394	0.476
LIG_deltaCOP1_diTrp_1	943	951	PF00928	0.333
LIG_FHA_1	1105	1111	PF00498	0.238
LIG_FHA_1	1144	1150	PF00498	0.695
LIG_FHA_1	1199	1205	PF00498	0.567
LIG_FHA_1	1377	1383	PF00498	0.352
LIG_FHA_1	1421	1427	PF00498	0.252
LIG_FHA_1	159	165	PF00498	0.615
LIG_FHA_1	197	203	PF00498	0.390
LIG_FHA_1	514	520	PF00498	0.466
LIG_FHA_1	583	589	PF00498	0.477
LIG_FHA_1	654	660	PF00498	0.409
LIG_FHA_1	708	714	PF00498	0.647
LIG_FHA_1	816	822	PF00498	0.545
LIG_FHA_1	841	847	PF00498	0.427
LIG_FHA_1	939	945	PF00498	0.397
LIG_FHA_2	1055	1061	PF00498	0.426
LIG_FHA_2	1161	1167	PF00498	0.443
LIG_FHA_2	1306	1312	PF00498	0.368
LIG_FHA_2	143	149	PF00498	0.529
LIG_FHA_2	593	599	PF00498	0.478
LIG_FHA_2	831	837	PF00498	0.462
LIG_FHA_2	847	853	PF00498	0.462
LIG_FHA_2	980	986	PF00498	0.599
LIG_FHA_2	988	994	PF00498	0.538
LIG_GBD_Chelix_1	1382	1390	PF00786	0.447
LIG_GBD_Chelix_1	395	403	PF00786	0.567
LIG_GBD_Chelix_1	837	845	PF00786	0.176
LIG_Integrin_isoDGR_2	40	42	PF01839	0.371
LIG_Integrin_RGD_1	1278	1280	PF01839	0.572
LIG_LIR_Apic_2	12	18	PF02991	0.700
LIG_LIR_Apic_2	682	688	PF02991	0.485
LIG_LIR_Apic_2	779	783	PF02991	0.524
LIG_LIR_Apic_2	982	986	PF02991	0.543
LIG_LIR_Gen_1	1016	1025	PF02991	0.416
LIG_LIR_Gen_1	1097	1105	PF02991	0.456
LIG_LIR_Gen_1	1257	1266	PF02991	0.558
LIG_LIR_Gen_1	1342	1351	PF02991	0.327
LIG_LIR_Gen_1	1368	1378	PF02991	0.325
LIG_LIR_Gen_1	1379	1386	PF02991	0.300
LIG_LIR_Gen_1	1389	1398	PF02991	0.481
LIG_LIR_Gen_1	1447	1457	PF02991	0.634
LIG_LIR_Gen_1	687	697	PF02991	0.406
LIG_LIR_Gen_1	734	743	PF02991	0.257
LIG_LIR_Gen_1	875	886	PF02991	0.404
LIG_LIR_Gen_1	943	952	PF02991	0.377
LIG_LIR_LC3C_4	394	397	PF02991	0.354
LIG_LIR_Nem_3	1016	1020	PF02991	0.416
LIG_LIR_Nem_3	1097	1102	PF02991	0.492
LIG_LIR_Nem_3	120	124	PF02991	0.424
LIG_LIR_Nem_3	1257	1263	PF02991	0.564
LIG_LIR_Nem_3	1342	1347	PF02991	0.298
LIG_LIR_Nem_3	1368	1373	PF02991	0.325
LIG_LIR_Nem_3	1379	1383	PF02991	0.293
LIG_LIR_Nem_3	1389	1394	PF02991	0.433
LIG_LIR_Nem_3	1447	1452	PF02991	0.648
LIG_LIR_Nem_3	646	651	PF02991	0.495
LIG_LIR_Nem_3	687	693	PF02991	0.411
LIG_LIR_Nem_3	734	739	PF02991	0.294
LIG_LIR_Nem_3	875	881	PF02991	0.531
LIG_LIR_Nem_3	943	948	PF02991	0.420
LIG_NRBOX	1342	1348	PF00104	0.306
LIG_NRBOX	964	970	PF00104	0.348
LIG_Pex14_2	1321	1325	PF04695	0.445
LIG_Pex14_2	648	652	PF04695	0.385
LIG_Pex14_2	763	767	PF04695	0.438
LIG_PTAP_UEV_1	274	279	PF05743	0.472
LIG_SH2_CRK	1380	1384	PF00017	0.430
LIG_SH2_CRK	1398	1402	PF00017	0.587
LIG_SH2_CRK	171	175	PF00017	0.530
LIG_SH2_CRK	290	294	PF00017	0.343
LIG_SH2_CRK	736	740	PF00017	0.328
LIG_SH2_CRK	780	784	PF00017	0.468
LIG_SH2_NCK_1	1380	1384	PF00017	0.338
LIG_SH2_NCK_1	1398	1402	PF00017	0.392
LIG_SH2_NCK_1	686	690	PF00017	0.570
LIG_SH2_NCK_1	736	740	PF00017	0.369
LIG_SH2_SRC	124	127	PF00017	0.464
LIG_SH2_STAP1	364	368	PF00017	0.388
LIG_SH2_STAP1	458	462	PF00017	0.413
LIG_SH2_STAP1	569	573	PF00017	0.461
LIG_SH2_STAP1	784	788	PF00017	0.376
LIG_SH2_STAP1	915	919	PF00017	0.451
LIG_SH2_STAT3	1116	1119	PF00017	0.286
LIG_SH2_STAT3	1319	1322	PF00017	0.324
LIG_SH2_STAT3	458	461	PF00017	0.349
LIG_SH2_STAT3	475	478	PF00017	0.428
LIG_SH2_STAT3	915	918	PF00017	0.483
LIG_SH2_STAT5	1017	1020	PF00017	0.424
LIG_SH2_STAT5	1070	1073	PF00017	0.557
LIG_SH2_STAT5	124	127	PF00017	0.355
LIG_SH2_STAT5	131	134	PF00017	0.352
LIG_SH2_STAT5	1319	1322	PF00017	0.408
LIG_SH2_STAT5	171	174	PF00017	0.513
LIG_SH2_STAT5	475	478	PF00017	0.431
LIG_SH2_STAT5	522	525	PF00017	0.471
LIG_SH2_STAT5	651	654	PF00017	0.361
LIG_SH2_STAT5	672	675	PF00017	0.326
LIG_SH2_STAT5	741	744	PF00017	0.357
LIG_SH3_1	104	110	PF00018	0.535
LIG_SH3_1	1398	1404	PF00018	0.592
LIG_SH3_3	1019	1025	PF00018	0.459
LIG_SH3_3	104	110	PF00018	0.704
LIG_SH3_3	1146	1152	PF00018	0.432
LIG_SH3_3	1307	1313	PF00018	0.450
LIG_SH3_3	1398	1404	PF00018	0.613
LIG_SH3_3	272	278	PF00018	0.625
LIG_SH3_3	537	543	PF00018	0.474
LIG_SH3_3	759	765	PF00018	0.456
LIG_SH3_3	93	99	PF00018	0.628
LIG_SH3_3	946	952	PF00018	0.467
LIG_SUMO_SIM_anti_2	1016	1022	PF11976	0.416
LIG_SUMO_SIM_anti_2	1215	1220	PF11976	0.322
LIG_SUMO_SIM_anti_2	835	843	PF11976	0.443
LIG_SUMO_SIM_par_1	1029	1035	PF11976	0.558
LIG_SUMO_SIM_par_1	1480	1491	PF11976	0.429
LIG_SUMO_SIM_par_1	203	208	PF11976	0.426
LIG_SUMO_SIM_par_1	394	401	PF11976	0.360
LIG_SUMO_SIM_par_1	794	801	PF11976	0.449
LIG_TRAF2_1	100	103	PF00917	0.600
LIG_TRAF2_1	145	148	PF00917	0.613
LIG_TRAF2_2	1448	1453	PF00917	0.399
LIG_TYR_ITIM	1118	1123	PF00017	0.234
LIG_TYR_ITIM	294	299	PF00017	0.328
LIG_TYR_ITSM	732	739	PF00017	0.286
LIG_UBA3_1	1390	1397	PF00899	0.572
LIG_UBA3_1	620	625	PF00899	0.357
LIG_UBA3_1	760	768	PF00899	0.321
LIG_UBA3_1	961	967	PF00899	0.447
LIG_WRC_WIRS_1	980	985	PF05994	0.528
LIG_WW_3	106	110	PF00397	0.529
MOD_CDC14_SPxK_1	1309	1312	PF00782	0.346
MOD_CDK_SPK_2	109	114	PF00069	0.487
MOD_CDK_SPxK_1	1306	1312	PF00069	0.376
MOD_CDK_SPxK_1	705	711	PF00069	0.450
MOD_CK1_1	1042	1048	PF00069	0.250
MOD_CK1_1	1073	1079	PF00069	0.374
MOD_CK1_1	1210	1216	PF00069	0.404
MOD_CK1_1	1290	1296	PF00069	0.337
MOD_CK1_1	1303	1309	PF00069	0.472
MOD_CK1_1	1339	1345	PF00069	0.313
MOD_CK1_1	1352	1358	PF00069	0.397
MOD_CK1_1	1433	1439	PF00069	0.460
MOD_CK1_1	189	195	PF00069	0.364
MOD_CK1_1	316	322	PF00069	0.648
MOD_CK1_1	382	388	PF00069	0.563
MOD_CK1_1	440	446	PF00069	0.383
MOD_CK1_1	547	553	PF00069	0.263
MOD_CK1_1	830	836	PF00069	0.271
MOD_CK1_1	853	859	PF00069	0.296
MOD_CK1_1	870	876	PF00069	0.294
MOD_CK1_1	89	95	PF00069	0.578
MOD_CK2_1	117	123	PF00069	0.514
MOD_CK2_1	1351	1357	PF00069	0.298
MOD_CK2_1	1386	1392	PF00069	0.278
MOD_CK2_1	1405	1411	PF00069	0.616
MOD_CK2_1	142	148	PF00069	0.541
MOD_CK2_1	547	553	PF00069	0.291
MOD_CK2_1	691	697	PF00069	0.539
MOD_CK2_1	784	790	PF00069	0.382
MOD_CK2_1	846	852	PF00069	0.467
MOD_CK2_1	979	985	PF00069	0.601
MOD_Cter_Amidation	1005	1008	PF01082	0.214
MOD_DYRK1A_RPxSP_1	109	113	PF00069	0.492
MOD_GlcNHglycan	1178	1181	PF01048	0.434
MOD_GlcNHglycan	1182	1186	PF01048	0.436
MOD_GlcNHglycan	1190	1193	PF01048	0.544
MOD_GlcNHglycan	126	130	PF01048	0.322
MOD_GlcNHglycan	1302	1305	PF01048	0.597
MOD_GlcNHglycan	1338	1341	PF01048	0.283
MOD_GlcNHglycan	1407	1410	PF01048	0.499
MOD_GlcNHglycan	1438	1441	PF01048	0.477
MOD_GlcNHglycan	151	154	PF01048	0.514
MOD_GlcNHglycan	275	278	PF01048	0.653
MOD_GlcNHglycan	319	322	PF01048	0.648
MOD_GlcNHglycan	387	390	PF01048	0.552
MOD_GlcNHglycan	419	422	PF01048	0.664
MOD_GlcNHglycan	427	430	PF01048	0.462
MOD_GlcNHglycan	546	549	PF01048	0.294
MOD_GlcNHglycan	639	642	PF01048	0.333
MOD_GlcNHglycan	771	774	PF01048	0.425
MOD_GlcNHglycan	786	789	PF01048	0.200
MOD_GlcNHglycan	803	806	PF01048	0.417
MOD_GlcNHglycan	815	818	PF01048	0.275
MOD_GlcNHglycan	829	832	PF01048	0.240
MOD_GlcNHglycan	872	875	PF01048	0.406
MOD_GlcNHglycan	895	898	PF01048	0.399
MOD_GSK3_1	1075	1082	PF00069	0.399
MOD_GSK3_1	1160	1167	PF00069	0.575
MOD_GSK3_1	1176	1183	PF00069	0.644
MOD_GSK3_1	1190	1197	PF00069	0.483
MOD_GSK3_1	1203	1210	PF00069	0.384
MOD_GSK3_1	1235	1242	PF00069	0.520
MOD_GSK3_1	1293	1300	PF00069	0.523
MOD_GSK3_1	1302	1309	PF00069	0.547
MOD_GSK3_1	1349	1356	PF00069	0.394
MOD_GSK3_1	1405	1412	PF00069	0.608
MOD_GSK3_1	185	192	PF00069	0.554
MOD_GSK3_1	269	276	PF00069	0.742
MOD_GSK3_1	304	311	PF00069	0.500
MOD_GSK3_1	313	320	PF00069	0.631
MOD_GSK3_1	335	342	PF00069	0.455
MOD_GSK3_1	410	417	PF00069	0.644
MOD_GSK3_1	579	586	PF00069	0.357
MOD_GSK3_1	675	682	PF00069	0.260
MOD_GSK3_1	705	712	PF00069	0.507
MOD_GSK3_1	716	723	PF00069	0.509
MOD_GSK3_1	752	759	PF00069	0.300
MOD_GSK3_1	784	791	PF00069	0.387
MOD_GSK3_1	79	86	PF00069	0.466
MOD_GSK3_1	797	804	PF00069	0.369
MOD_GSK3_1	846	853	PF00069	0.344
MOD_GSK3_1	864	871	PF00069	0.349
MOD_GSK3_1	905	912	PF00069	0.249
MOD_LATS_1	480	486	PF00433	0.378
MOD_LATS_1	530	536	PF00433	0.225
MOD_N-GLC_1	1405	1410	PF02516	0.620
MOD_N-GLC_1	180	185	PF02516	0.552
MOD_N-GLC_1	752	757	PF02516	0.416
MOD_N-GLC_1	919	924	PF02516	0.315
MOD_NEK2_1	1032	1037	PF00069	0.458
MOD_NEK2_1	1104	1109	PF00069	0.388
MOD_NEK2_1	1334	1339	PF00069	0.396
MOD_NEK2_1	1386	1391	PF00069	0.362
MOD_NEK2_1	180	185	PF00069	0.520
MOD_NEK2_1	196	201	PF00069	0.359
MOD_NEK2_1	213	218	PF00069	0.483
MOD_NEK2_1	639	644	PF00069	0.312
MOD_NEK2_1	797	802	PF00069	0.274
MOD_NEK2_1	845	850	PF00069	0.467
MOD_NEK2_1	944	949	PF00069	0.454
MOD_NEK2_2	487	492	PF00069	0.413
MOD_NEK2_2	815	820	PF00069	0.225
MOD_PIKK_1	1073	1079	PF00454	0.301
MOD_PIKK_1	1287	1293	PF00454	0.575
MOD_PIKK_1	1381	1387	PF00454	0.325
MOD_PIKK_1	25	31	PF00454	0.374
MOD_PIKK_1	398	404	PF00454	0.445
MOD_PIKK_1	474	480	PF00454	0.427
MOD_PIKK_1	514	520	PF00454	0.356
MOD_PIKK_1	538	544	PF00454	0.328
MOD_PIKK_1	720	726	PF00454	0.450
MOD_PIKK_1	906	912	PF00454	0.266
MOD_PIKK_1	914	920	PF00454	0.290
MOD_PIKK_1	928	934	PF00454	0.283
MOD_PKA_1	482	488	PF00069	0.392
MOD_PKA_1	544	550	PF00069	0.290
MOD_PKA_2	1137	1143	PF00069	0.459
MOD_PKA_2	1210	1216	PF00069	0.506
MOD_PKA_2	1376	1382	PF00069	0.351
MOD_PKA_2	1386	1392	PF00069	0.344
MOD_PKA_2	158	164	PF00069	0.597
MOD_PKA_2	172	178	PF00069	0.415
MOD_PKA_2	445	451	PF00069	0.436
MOD_PKA_2	481	487	PF00069	0.465
MOD_PKA_2	544	550	PF00069	0.273
MOD_PKA_2	558	564	PF00069	0.335
MOD_PKA_2	629	635	PF00069	0.185
MOD_PKA_2	853	859	PF00069	0.387
MOD_PKB_1	435	443	PF00069	0.377
MOD_Plk_1	1164	1170	PF00069	0.568
MOD_Plk_1	1360	1366	PF00069	0.424
MOD_Plk_1	1405	1411	PF00069	0.611
MOD_Plk_1	185	191	PF00069	0.529
MOD_Plk_1	196	202	PF00069	0.322
MOD_Plk_1	440	446	PF00069	0.460
MOD_Plk_1	992	998	PF00069	0.280
MOD_Plk_2-3	1160	1166	PF00069	0.594
MOD_Plk_2-3	117	123	PF00069	0.580
MOD_Plk_2-3	1453	1459	PF00069	0.542
MOD_Plk_2-3	1485	1491	PF00069	0.613
MOD_Plk_4	1032	1038	PF00069	0.459
MOD_Plk_4	1039	1045	PF00069	0.384
MOD_Plk_4	1339	1345	PF00069	0.301
MOD_Plk_4	1386	1392	PF00069	0.446
MOD_Plk_4	1453	1459	PF00069	0.542
MOD_Plk_4	172	178	PF00069	0.537
MOD_Plk_4	186	192	PF00069	0.524
MOD_Plk_4	196	202	PF00069	0.313
MOD_Plk_4	278	284	PF00069	0.590
MOD_Plk_4	323	329	PF00069	0.628
MOD_Plk_4	756	762	PF00069	0.276
MOD_Plk_4	979	985	PF00069	0.567
MOD_ProDKin_1	1009	1015	PF00069	0.288
MOD_ProDKin_1	109	115	PF00069	0.598
MOD_ProDKin_1	1128	1134	PF00069	0.571
MOD_ProDKin_1	1306	1312	PF00069	0.544
MOD_ProDKin_1	1420	1426	PF00069	0.287
MOD_ProDKin_1	1430	1436	PF00069	0.475
MOD_ProDKin_1	1444	1450	PF00069	0.545
MOD_ProDKin_1	304	310	PF00069	0.525
MOD_ProDKin_1	379	385	PF00069	0.569
MOD_ProDKin_1	653	659	PF00069	0.459
MOD_ProDKin_1	684	690	PF00069	0.432
MOD_ProDKin_1	705	711	PF00069	0.655
MOD_ProDKin_1	83	89	PF00069	0.656
MOD_ProDKin_1	872	878	PF00069	0.467
MOD_ProDKin_1	92	98	PF00069	0.548
MOD_SUMO_rev_2	1505	1515	PF00179	0.488
MOD_SUMO_rev_2	750	760	PF00179	0.394
TRG_DiLeu_BaEn_1	1016	1021	PF01217	0.242
TRG_DiLeu_BaEn_2	196	202	PF01217	0.319
TRG_DiLeu_BaLyEn_6	1416	1421	PF01217	0.314
TRG_DiLeu_BaLyEn_6	235	240	PF01217	0.316
TRG_ENDOCYTIC_2	1017	1020	PF00928	0.364
TRG_ENDOCYTIC_2	1087	1090	PF00928	0.354
TRG_ENDOCYTIC_2	1120	1123	PF00928	0.390
TRG_ENDOCYTIC_2	1380	1383	PF00928	0.439
TRG_ENDOCYTIC_2	290	293	PF00928	0.413
TRG_ENDOCYTIC_2	296	299	PF00928	0.388
TRG_ENDOCYTIC_2	736	739	PF00928	0.340
TRG_ENDOCYTIC_2	937	940	PF00928	0.371
TRG_ER_diArg_1	1272	1274	PF00400	0.506
TRG_ER_diArg_1	1330	1332	PF00400	0.260
TRG_ER_diArg_1	1418	1420	PF00400	0.455
TRG_ER_diArg_1	164	166	PF00400	0.607
TRG_ER_diArg_1	255	258	PF00400	0.747
TRG_ER_diArg_1	469	471	PF00400	0.499
TRG_ER_diArg_1	481	483	PF00400	0.417
TRG_ER_diArg_1	501	504	PF00400	0.242
TRG_ER_diArg_1	543	545	PF00400	0.328
TRG_ER_diArg_1	633	636	PF00400	0.354
TRG_ER_FFAT_2	679	691	PF00635	0.486
TRG_NES_CRM1_1	1009	1024	PF08389	0.242
TRG_NES_CRM1_1	598	609	PF08389	0.432
TRG_NLS_MonoCore_2	1065	1070	PF00514	0.454
TRG_NLS_MonoExtN_4	1066	1071	PF00514	0.457
TRG_Pf-PMV_PEXEL_1	238	242	PF00026	0.398
TRG_Pf-PMV_PEXEL_1	291	295	PF00026	0.327
TRG_Pf-PMV_PEXEL_1	671	675	PF00026	0.353
TRG_Pf-PMV_PEXEL_1	942	946	PF00026	0.377

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5H2	Leptomonas seymouri	59%	83%
A0A0S4ILP1	Bodo saltans	29%	71%
A0A0S4IND4	Bodo saltans	34%	89%
A0A1X0P9B9	Trypanosomatidae	43%	100%
A0A1X0P9W8	Trypanosomatidae	31%	69%
A0A3R7M0Y1	Trypanosoma rangeli	30%	70%
A0A3R7MLF0	Trypanosoma rangeli	44%	100%
A0A3S7WQG7	Leishmania donovani	30%	100%
A4HAN8	Leishmania braziliensis	78%	100%
A4HB41	Leishmania braziliensis	32%	68%
A4HDG6	Leishmania braziliensis	26%	100%
A4HTS5	Leishmania infantum	30%	100%
A4I9T1	Leishmania infantum	100%	100%
C9ZM05	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	70%
C9ZMU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9AMK8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B4U2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9B5B2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	68%
Q4Q2M1	Leishmania major	31%	68%
Q4Q384	Leishmania major	92%	100%
Q581T1	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	29%	70%
V5BKW2	Trypanosoma cruzi	32%	95%
V5BND8	Trypanosoma cruzi	44%	100%