Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine-protein phosphatase PP1, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X7J8_LEIDO

TriTrypDb:

LdBPK_340900.1 , LdCL_340014500 , LDHU3_34.1440

Length:

296

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X7J8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X7J8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	13
GO:0004721	phosphoprotein phosphatase activity	3	13
GO:0004722	protein serine/threonine phosphatase activity	4	13
GO:0016787	hydrolase activity	2	13
GO:0016788	hydrolase activity, acting on ester bonds	3	13
GO:0016791	phosphatase activity	5	13
GO:0017018	myosin phosphatase activity	5	13
GO:0042578	phosphoric ester hydrolase activity	4	13
GO:0140096	catalytic activity, acting on a protein	2	13
GO:0003676	nucleic acid binding	3	1
GO:0003746	translation elongation factor activity	4	1
GO:0005488	binding	1	1
GO:0008135	translation factor activity, RNA binding	3	1
GO:0045182	translation regulator activity	1	1
GO:0090079	translation regulator activity, nucleic acid binding	2	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	138	140	PF00675	0.232
CLV_NRD_NRD_1	257	259	PF00675	0.375
CLV_NRD_NRD_1	36	38	PF00675	0.326
CLV_PCSK_KEX2_1	112	114	PF00082	0.395
CLV_PCSK_KEX2_1	137	139	PF00082	0.232
CLV_PCSK_KEX2_1	229	231	PF00082	0.279
CLV_PCSK_KEX2_1	257	259	PF00082	0.377
CLV_PCSK_KEX2_1	36	38	PF00082	0.326
CLV_PCSK_PC1ET2_1	112	114	PF00082	0.388
CLV_PCSK_PC1ET2_1	137	139	PF00082	0.232
CLV_PCSK_PC1ET2_1	229	231	PF00082	0.388
CLV_PCSK_PC7_1	32	38	PF00082	0.336
CLV_PCSK_SKI1_1	143	147	PF00082	0.282
CLV_PCSK_SKI1_1	187	191	PF00082	0.195
CLV_PCSK_SKI1_1	258	262	PF00082	0.292
CLV_PCSK_SKI1_1	32	36	PF00082	0.304
CLV_PCSK_SKI1_1	39	43	PF00082	0.317
CLV_PCSK_SKI1_1	82	86	PF00082	0.260
DEG_APCC_DBOX_1	31	39	PF00400	0.311
DOC_CYCLIN_RxL_1	184	194	PF00134	0.195
DOC_CYCLIN_RxL_1	79	88	PF00134	0.287
DOC_MAPK_gen_1	137	144	PF00069	0.255
DOC_MAPK_gen_1	229	237	PF00069	0.260
DOC_MAPK_HePTP_8	227	239	PF00069	0.260
DOC_MAPK_MEF2A_6	230	239	PF00069	0.237
DOC_MAPK_MEF2A_6	27	35	PF00069	0.330
DOC_MAPK_RevD_3	100	113	PF00069	0.388
DOC_PP1_RVXF_1	215	222	PF00149	0.338
DOC_PP2B_LxvP_1	189	192	PF13499	0.245
DOC_SPAK_OSR1_1	139	143	PF12202	0.232
DOC_USP7_MATH_2	205	211	PF00917	0.279
DOC_WW_Pin1_4	170	175	PF00397	0.232
LIG_14-3-3_CanoR_1	20	26	PF00244	0.401
LIG_14-3-3_CanoR_1	217	222	PF00244	0.232
LIG_Actin_WH2_2	165	182	PF00022	0.304
LIG_Actin_WH2_2	23	38	PF00022	0.315
LIG_AP2alpha_1	148	152	PF02296	0.232
LIG_APCC_ABBA_1	142	147	PF00400	0.245
LIG_BRCT_BRCA1_1	219	223	PF00533	0.250
LIG_FHA_1	11	17	PF00498	0.346
LIG_FHA_1	121	127	PF00498	0.388
LIG_FHA_1	64	70	PF00498	0.335
LIG_FHA_1	95	101	PF00498	0.253
LIG_FHA_2	220	226	PF00498	0.249
LIG_LIR_Apic_2	199	205	PF02991	0.232
LIG_LIR_Gen_1	147	156	PF02991	0.232
LIG_LIR_Gen_1	248	259	PF02991	0.320
LIG_LIR_Gen_1	288	296	PF02991	0.341
LIG_LIR_Gen_1	7	17	PF02991	0.454
LIG_LIR_Gen_1	81	90	PF02991	0.256
LIG_LIR_Nem_3	147	151	PF02991	0.232
LIG_LIR_Nem_3	183	189	PF02991	0.388
LIG_LIR_Nem_3	248	254	PF02991	0.343
LIG_LIR_Nem_3	288	292	PF02991	0.312
LIG_LIR_Nem_3	7	12	PF02991	0.454
LIG_LIR_Nem_3	81	86	PF02991	0.256
LIG_MYND_1	188	192	PF01753	0.195
LIG_Pex14_2	148	152	PF04695	0.232
LIG_REV1ctd_RIR_1	251	262	PF16727	0.282
LIG_SH2_CRK	186	190	PF00017	0.388
LIG_SH2_CRK	9	13	PF00017	0.438
LIG_SH2_NCK_1	9	13	PF00017	0.438
LIG_SH2_STAP1	251	255	PF00017	0.321
LIG_SH2_STAT5	115	118	PF00017	0.298
LIG_SH2_STAT5	268	271	PF00017	0.341
LIG_SH2_STAT5	83	86	PF00017	0.232
LIG_SH2_STAT5	89	92	PF00017	0.232
LIG_SH2_STAT5	9	12	PF00017	0.436
LIG_SH3_3	105	111	PF00018	0.260
LIG_SUMO_SIM_anti_2	21	29	PF11976	0.485
LIG_SUMO_SIM_anti_2	97	104	PF11976	0.245
LIG_SUMO_SIM_par_1	187	194	PF11976	0.246
LIG_SUMO_SIM_par_1	258	264	PF11976	0.257
LIG_UBA3_1	103	107	PF00899	0.235
LIG_WRC_WIRS_1	286	291	PF05994	0.451
MOD_CDK_SPxxK_3	170	177	PF00069	0.245
MOD_CK1_1	21	27	PF00069	0.481
MOD_CK1_1	7	13	PF00069	0.483
MOD_CK2_1	200	206	PF00069	0.279
MOD_CK2_1	219	225	PF00069	0.283
MOD_Cter_Amidation	255	258	PF01082	0.448
MOD_GlcNHglycan	20	23	PF01048	0.444
MOD_GlcNHglycan	209	212	PF01048	0.279
MOD_GlcNHglycan	263	266	PF01048	0.300
MOD_GlcNHglycan	274	277	PF01048	0.338
MOD_GSK3_1	7	14	PF00069	0.502
MOD_GSK3_1	94	101	PF00069	0.346
MOD_N-GLC_2	267	269	PF02516	0.308
MOD_N-GLC_2	56	58	PF02516	0.245
MOD_NEK2_1	11	16	PF00069	0.311
MOD_NEK2_1	231	236	PF00069	0.298
MOD_NEK2_1	263	268	PF00069	0.273
MOD_NEK2_1	272	277	PF00069	0.304
MOD_PIKK_1	41	47	PF00454	0.348
MOD_Plk_1	4	10	PF00069	0.349
MOD_Plk_4	11	17	PF00069	0.272
MOD_Plk_4	21	27	PF00069	0.548
MOD_Plk_4	249	255	PF00069	0.328
MOD_Plk_4	258	264	PF00069	0.224
MOD_Plk_4	4	10	PF00069	0.346
MOD_ProDKin_1	170	176	PF00069	0.232
MOD_SUMO_for_1	292	295	PF00179	0.473
TRG_DiLeu_BaLyEn_6	185	190	PF01217	0.271
TRG_DiLeu_BaLyEn_6	29	34	PF01217	0.468
TRG_ENDOCYTIC_2	130	133	PF00928	0.294
TRG_ENDOCYTIC_2	186	189	PF00928	0.388
TRG_ENDOCYTIC_2	251	254	PF00928	0.290
TRG_ENDOCYTIC_2	83	86	PF00928	0.232
TRG_ENDOCYTIC_2	9	12	PF00928	0.436
TRG_ER_diArg_1	138	140	PF00400	0.232
TRG_ER_diArg_1	257	259	PF00400	0.370
TRG_ER_diArg_1	35	37	PF00400	0.310
TRG_Pf-PMV_PEXEL_1	177	181	PF00026	0.260

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	59%	98%
A0A0N1HSR2	Leptomonas seymouri	46%	79%
A0A0N1I0V3	Leptomonas seymouri	94%	75%
A0A0N1IBK9	Leptomonas seymouri	40%	96%
A0A0N1ILH2	Leptomonas seymouri	31%	70%
A0A0N1P9X9	Leptomonas seymouri	41%	96%
A0A0N1PAV9	Leptomonas seymouri	58%	81%
A0A0N1PCC5	Leptomonas seymouri	42%	96%
A0A0N1PDK9	Leptomonas seymouri	45%	93%
A0A0S4IIW0	Bodo saltans	35%	75%
A0A0S4ILF8	Bodo saltans	41%	97%
A0A0S4J1J1	Bodo saltans	37%	76%
A0A0S4JJ52	Bodo saltans	56%	78%
A0A0S4JJ96	Bodo saltans	69%	94%
A0A0S4JJH3	Bodo saltans	57%	94%
A0A0S4KGD7	Bodo saltans	46%	100%
A0A0S4KKU2	Bodo saltans	43%	97%
A0A0S4KM73	Bodo saltans	45%	74%
A0A1X0NK88	Trypanosomatidae	56%	86%
A0A1X0NNN6	Trypanosomatidae	46%	89%
A0A1X0NS37	Trypanosomatidae	40%	100%
A0A1X0NS65	Trypanosomatidae	43%	98%
A0A1X0NUA6	Trypanosomatidae	42%	74%
A0A1X0NYR5	Trypanosomatidae	57%	98%
A0A1X0P6J3	Trypanosomatidae	34%	78%
A0A1X0P7H9	Trypanosomatidae	35%	66%
A0A1X0P7Q5	Trypanosomatidae	31%	76%
A0A1X0P982	Trypanosomatidae	82%	89%
A0A1X0PA67	Trypanosomatidae	57%	100%
A0A1X0PAK9	Trypanosomatidae	56%	100%
A0A1X0PBJ2	Trypanosomatidae	41%	97%
A0A3Q8I8M6	Leishmania donovani	34%	68%
A0A3Q8IFB2	Leishmania donovani	52%	100%
A0A3Q8IH18	Leishmania donovani	41%	100%
A0A3Q8IHY7	Leishmania donovani	57%	100%
A0A3R7KQR6	Trypanosoma rangeli	46%	87%
A0A3R7M399	Trypanosoma rangeli	33%	68%
A0A3R7MBA3	Trypanosoma rangeli	36%	66%
A0A3R7MFZ7	Trypanosoma rangeli	80%	90%
A0A3R7MM48	Trypanosoma rangeli	43%	74%
A0A3R7N275	Trypanosoma rangeli	57%	98%
A0A3R7NP99	Trypanosoma rangeli	39%	97%
A0A3S5H6T9	Leishmania donovani	43%	100%
A0A3S5H7Q6	Leishmania donovani	56%	100%
A0A3S7WZ39	Leishmania donovani	45%	100%
A0A3S7X190	Leishmania donovani	57%	100%
A0A3S7X1Y0	Leishmania donovani	41%	100%
A0A3S7X7I6	Leishmania donovani	55%	100%
A0A3S7X7K2	Leishmania donovani	56%	97%
A0A3S7X8K6	Leishmania donovani	40%	96%
A0A3S7XAY3	Leishmania donovani	29%	73%
A0A422N8P1	Trypanosoma rangeli	56%	100%
A0A422N9D5	Trypanosoma rangeli	33%	75%
A0A422NKG0	Trypanosoma rangeli	41%	97%
A0A422NPG1	Trypanosoma rangeli	58%	85%
A0A422NYN7	Trypanosoma rangeli	41%	98%
A0A422P483	Trypanosoma rangeli	36%	69%
A0C1E4	Paramecium tetraurelia	43%	97%
A0CCD2	Paramecium tetraurelia	44%	97%
A0CNL9	Paramecium tetraurelia	43%	94%
A0DJ90	Paramecium tetraurelia	43%	98%
A2X2G3	Oryza sativa subsp. indica	45%	96%
A2XN40	Oryza sativa subsp. indica	43%	96%
A2YEB4	Oryza sativa subsp. indica	45%	97%
A3C4N5	Oryza sativa subsp. japonica	43%	94%
A4H7Z3	Leishmania braziliensis	43%	100%
A4HAI7	Leishmania braziliensis	51%	100%
A4HAI8	Leishmania braziliensis	56%	100%
A4HAI9	Leishmania braziliensis	55%	100%
A4HAJ8	Leishmania braziliensis	98%	100%
A4HBE2	Leishmania braziliensis	41%	100%
A4HE75	Leishmania braziliensis	44%	100%
A4HGA9	Leishmania braziliensis	57%	100%
A4HGX0	Leishmania braziliensis	44%	100%
A4HJQ1	Leishmania braziliensis	56%	100%
A4HKU9	Leishmania braziliensis	41%	100%
A4HP65	Leishmania braziliensis	30%	100%
A4HVT0	Leishmania infantum	34%	68%
A4HWC1	Leishmania infantum	43%	100%
A4I1H6	Leishmania infantum	45%	100%
A4I3E3	Leishmania infantum	57%	100%
A4I400	Leishmania infantum	41%	100%
A4I768	Leishmania infantum	56%	100%
A4I8C8	Leishmania infantum	41%	100%
A4I9P2	Leishmania infantum	100%	100%
A4IAJ0	Leishmania infantum	40%	100%
A4IDH0	Leishmania infantum	29%	100%
A6H772	Bos taurus	44%	96%
A8WGP3	Danio rerio	43%	95%
A8XE00	Caenorhabditis briggsae	44%	89%
A9JRC7	Danio rerio	44%	96%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	46%	92%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	69%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	86%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	77%	91%
C9ZN04	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	80%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	55%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	86%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	69%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	76%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	98%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	97%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	98%
E9AHS8	Leishmania infantum	55%	100%
E9AHS9	Leishmania infantum	55%	100%
E9AHT0	Leishmania infantum	52%	100%
E9AHT1	Leishmania infantum	55%	100%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	57%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	53%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
G5EGK8	Caenorhabditis elegans	44%	93%
O00743	Homo sapiens	42%	97%
O02658	Caenorhabditis elegans	49%	97%
O04856	Nicotiana tabacum	56%	93%
O04857	Nicotiana tabacum	57%	95%
O04858	Nicotiana tabacum	55%	97%
O04860	Nicotiana tabacum	43%	94%
O04951	Arabidopsis thaliana	44%	96%
O15757	Dictyostelium discoideum	59%	92%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	85%
O76932	Drosophila melanogaster	43%	96%
O82733	Arabidopsis thaliana	58%	89%
O82734	Arabidopsis thaliana	59%	91%
P0C5D7	Oryza sativa subsp. indica	44%	94%
P11084	Oryctolagus cuniculus	44%	96%
P11493	Sus scrofa	46%	100%
P11611	Oryctolagus cuniculus	43%	96%
P11612	Drosophila melanogaster	54%	94%
P12982	Drosophila melanogaster	58%	98%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	59%	91%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	95%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	55%	92%
P22198	Zea mays	59%	94%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	80%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	79%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	96%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	92%
P23696	Drosophila melanogaster	45%	96%
P23733	Trypanosoma brucei brucei	57%	86%
P23734	Trypanosoma brucei brucei	57%	86%
P23777	Brassica napus	62%	100%
P23778	Brassica napus	44%	96%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	56%	92%
P30366	Arabidopsis thaliana	60%	93%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	96%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	95%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	37%	80%
P34350	Caenorhabditis elegans	32%	78%
P34430	Caenorhabditis elegans	25%	100%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	42%	97%
P36873	Homo sapiens	58%	92%
P36874	Xenopus laevis	58%	92%
P48458	Caenorhabditis elegans	49%	81%
P48461	Drosophila melanogaster	58%	91%
P48462	Drosophila melanogaster	55%	90%
P48463	Gallus gallus	46%	96%
P48480	Acetabularia peniculus	60%	93%
P48481	Acetabularia peniculus	59%	93%
P48482	Arabidopsis thaliana	59%	95%
P48483	Arabidopsis thaliana	54%	92%
P48484	Arabidopsis thaliana	60%	92%
P48485	Arabidopsis thaliana	59%	95%
P48486	Arabidopsis thaliana	56%	92%
P48487	Brassica oleracea	60%	94%
P48488	Medicago sativa subsp. varia	56%	92%
P48489	Oryza sativa subsp. japonica	61%	92%
P48490	Phaseolus vulgaris	57%	94%
P48528	Arabidopsis thaliana	46%	97%
P48529	Arabidopsis thaliana	43%	97%
P48577	Acetabularia peniculus	46%	96%
P48578	Arabidopsis thaliana	43%	95%
P48579	Helianthus annuus	46%	97%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	46%	91%
P48726	Paramecium tetraurelia	43%	94%
P48727	Caenorhabditis elegans	58%	89%
P49576	Paramecium tetraurelia	43%	98%
P60510	Homo sapiens	44%	96%
P61287	Bos taurus	58%	92%
P61292	Sus scrofa	55%	91%
P62136	Homo sapiens	58%	90%
P62137	Mus musculus	58%	90%
P62138	Rattus norvegicus	58%	90%
P62139	Oryctolagus cuniculus	58%	90%
P62140	Homo sapiens	55%	91%
P62141	Mus musculus	55%	91%
P62142	Rattus norvegicus	55%	91%
P62143	Oryctolagus cuniculus	55%	91%
P62207	Gallus gallus	55%	91%
P62714	Homo sapiens	46%	96%
P62715	Mus musculus	46%	96%
P62716	Rattus norvegicus	46%	96%
P63087	Mus musculus	58%	92%
P63088	Rattus norvegicus	58%	92%
P63330	Mus musculus	43%	96%
P63331	Rattus norvegicus	43%	96%
P67774	Bos taurus	43%	96%
P67775	Homo sapiens	43%	96%
P67776	Sus scrofa	43%	96%
P67777	Oryctolagus cuniculus	43%	96%
P91420	Caenorhabditis elegans	48%	97%
P97470	Mus musculus	44%	96%
Q05547	Drosophila melanogaster	57%	98%
Q06009	Medicago sativa	42%	95%
Q07098	Arabidopsis thaliana	44%	97%
Q07099	Arabidopsis thaliana	44%	97%
Q07100	Arabidopsis thaliana	43%	95%
Q09496	Caenorhabditis elegans	40%	89%
Q0DBD3	Oryza sativa subsp. japonica	45%	97%
Q0E2S4	Oryza sativa subsp. japonica	45%	96%
Q0P594	Bos taurus	46%	96%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	96%
Q10BT5	Oryza sativa subsp. japonica	43%	96%
Q27497	Caenorhabditis elegans	56%	90%
Q27884	Drosophila melanogaster	44%	98%
Q3SWW9	Bos taurus	55%	91%
Q3T0E7	Bos taurus	58%	90%
Q4Q1M5	Leishmania major	29%	100%
Q4Q2C2	Leishmania major	41%	100%
Q4Q3C0	Leishmania major	99%	100%
Q4Q3C5	Leishmania major	55%	100%
Q4Q3C6	Leishmania major	52%	100%
Q4Q3C7	Leishmania major	52%	100%
Q4Q3C8	Leishmania major	54%	100%
Q4Q4W8	Leishmania major	41%	100%
Q4Q5Z8	Leishmania major	54%	100%
Q4Q7Z5	Leishmania major	41%	100%
Q4Q8K1	Leishmania major	56%	100%
Q4Q9W1	Leishmania major	45%	100%
Q4QFG0	Leishmania major	43%	100%
Q4QG03	Leishmania major	34%	68%
Q4WM22	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	76%
Q54RD6	Dictyostelium discoideum	40%	95%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	41%	94%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	40%	71%
Q5BJ92	Rattus norvegicus	44%	96%
Q5I085	Xenopus tropicalis	57%	91%
Q5R6K8	Pongo abelii	44%	96%
Q5R740	Pongo abelii	55%	91%
Q61JR3	Caenorhabditis briggsae	56%	90%
Q627N3	Caenorhabditis briggsae	58%	89%
Q64620	Rattus norvegicus	42%	97%
Q6BFF6	Paramecium tetraurelia	43%	94%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	40%	96%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	40%	96%
Q6GQL2	Xenopus laevis	57%	91%
Q6IP91	Xenopus laevis	44%	96%
Q6NVU2	Xenopus tropicalis	58%	92%
Q6P861	Xenopus tropicalis	44%	96%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	39%	95%
Q7SZ10	Xenopus laevis	58%	92%
Q8LSN3	Pisum sativum	42%	98%
Q8MJ46	Canis lupus familiaris	58%	92%
Q8MJ47	Canis lupus familiaris	55%	91%
Q8WMS6	Canis lupus familiaris	58%	90%
Q8X178	Blumeria hordei	45%	90%
Q9CQR6	Mus musculus	42%	97%
Q9FN02	Arabidopsis thaliana	31%	72%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	47%	90%
Q9LHE7	Arabidopsis thaliana	42%	98%
Q9M9W3	Arabidopsis thaliana	59%	93%
Q9SX52	Arabidopsis thaliana	42%	98%
Q9U9A3	Dictyostelium discoideum	44%	97%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	58%	96%
Q9XGH7	Nicotiana tabacum	43%	95%
Q9XTT8	Caenorhabditis elegans	44%	92%
Q9XW79	Caenorhabditis elegans	44%	89%
Q9XZE5	Dictyostelium discoideum	46%	97%
Q9Y0B7	Dictyostelium discoideum	44%	97%
Q9ZSE4	Hevea brasiliensis	46%	97%
V5AUW3	Trypanosoma cruzi	80%	90%
V5B3V2	Trypanosoma cruzi	36%	77%
V5B5K9	Trypanosoma cruzi	40%	88%
V5B8G5	Trypanosoma cruzi	46%	87%
V5BBR3	Trypanosoma cruzi	34%	76%
V5BGM0	Trypanosoma cruzi	44%	74%
V5BKU4	Trypanosoma cruzi	57%	98%
V5BQD7	Trypanosoma cruzi	33%	68%
V5D2G9	Trypanosoma cruzi	58%	84%
V5DAX7	Trypanosoma cruzi	56%	100%
V5DCW3	Trypanosoma cruzi	41%	97%
V5DIG8	Trypanosoma cruzi	38%	68%
V5DMS5	Trypanosoma cruzi	39%	97%