Zn-finger in Ran binding protein and others, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Zn-finger in Ran binding protein and others, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X7C0_LEIDO

TriTrypDb:

LdCL_330041300 , LDHU3_33.4860

Length:

304

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X7C0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X7C0

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	8
GO:0043167	ion binding	2	8
GO:0043169	cation binding	3	8
GO:0046872	metal ion binding	4	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	80	84	PF00656	0.643
CLV_NRD_NRD_1	204	206	PF00675	0.371
CLV_NRD_NRD_1	243	245	PF00675	0.231
CLV_PCSK_KEX2_1	248	250	PF00082	0.311
CLV_PCSK_KEX2_1	58	60	PF00082	0.359
CLV_PCSK_PC1ET2_1	248	250	PF00082	0.230
CLV_PCSK_PC1ET2_1	58	60	PF00082	0.359
CLV_PCSK_PC7_1	244	250	PF00082	0.230
CLV_PCSK_SKI1_1	206	210	PF00082	0.393
CLV_PCSK_SKI1_1	222	226	PF00082	0.601
DEG_Nend_Nbox_1	1	3	PF02207	0.490
DEG_SPOP_SBC_1	169	173	PF00917	0.440
DEG_SPOP_SBC_1	87	91	PF00917	0.671
DOC_USP7_MATH_1	151	155	PF00917	0.672
DOC_USP7_MATH_1	169	173	PF00917	0.670
DOC_USP7_MATH_1	210	214	PF00917	0.443
DOC_USP7_MATH_1	282	286	PF00917	0.421
DOC_USP7_MATH_1	87	91	PF00917	0.621
DOC_WW_Pin1_4	297	302	PF00397	0.454
DOC_WW_Pin1_4	66	71	PF00397	0.639
LIG_14-3-3_CanoR_1	200	208	PF00244	0.389
LIG_14-3-3_CanoR_1	222	228	PF00244	0.517
LIG_14-3-3_CanoR_1	28	34	PF00244	0.541
LIG_DCNL_PONY_1	1	4	PF03556	0.492
LIG_EVH1_2	180	184	PF00568	0.418
LIG_FHA_1	119	125	PF00498	0.337
LIG_FHA_1	63	69	PF00498	0.493
LIG_FHA_2	157	163	PF00498	0.494
LIG_FHA_2	171	177	PF00498	0.413
LIG_FHA_2	216	222	PF00498	0.602
LIG_LIR_Apic_2	101	107	PF02991	0.337
LIG_LIR_Apic_2	230	234	PF02991	0.340
LIG_LIR_Nem_3	145	150	PF02991	0.512
LIG_LIR_Nem_3	242	246	PF02991	0.230
LIG_MYND_1	128	132	PF01753	0.443
LIG_PTB_Apo_2	42	49	PF02174	0.445
LIG_SH2_STAP1	29	33	PF00017	0.448
LIG_SH2_STAT5	110	113	PF00017	0.484
LIG_SH3_3	177	183	PF00018	0.452
LIG_SH3_3	64	70	PF00018	0.483
LIG_SH3_3	7	13	PF00018	0.666
LIG_SUMO_SIM_anti_2	69	76	PF11976	0.583
LIG_TRAF2_1	218	221	PF00917	0.456
MOD_CDK_SPK_2	297	302	PF00069	0.445
MOD_CK1_1	155	161	PF00069	0.719
MOD_CK1_1	172	178	PF00069	0.470
MOD_CK1_1	199	205	PF00069	0.421
MOD_CK1_1	213	219	PF00069	0.556
MOD_CK1_1	268	274	PF00069	0.627
MOD_CK1_1	69	75	PF00069	0.608
MOD_CK2_1	215	221	PF00069	0.611
MOD_CK2_1	88	94	PF00069	0.680
MOD_GlcNHglycan	144	147	PF01048	0.688
MOD_GlcNHglycan	215	218	PF01048	0.521
MOD_GlcNHglycan	262	265	PF01048	0.597
MOD_GlcNHglycan	31	34	PF01048	0.564
MOD_GSK3_1	108	115	PF00069	0.516
MOD_GSK3_1	135	142	PF00069	0.698
MOD_GSK3_1	151	158	PF00069	0.674
MOD_GSK3_1	168	175	PF00069	0.454
MOD_GSK3_1	209	216	PF00069	0.566
MOD_GSK3_1	256	263	PF00069	0.568
MOD_GSK3_1	265	272	PF00069	0.603
MOD_GSK3_1	47	54	PF00069	0.422
MOD_GSK3_1	62	69	PF00069	0.412
MOD_GSK3_1	82	89	PF00069	0.586
MOD_N-GLC_1	112	117	PF02516	0.437
MOD_N-GLC_1	196	201	PF02516	0.249
MOD_N-GLC_1	213	218	PF02516	0.388
MOD_N-GLC_1	239	244	PF02516	0.455
MOD_NEK2_1	112	117	PF00069	0.317
MOD_NEK2_1	170	175	PF00069	0.439
MOD_NEK2_1	223	228	PF00069	0.492
MOD_PIKK_1	112	118	PF00454	0.320
MOD_PIKK_1	23	29	PF00454	0.459
MOD_PKA_1	248	254	PF00069	0.230
MOD_PKA_1	57	63	PF00069	0.384
MOD_PKA_2	199	205	PF00069	0.365
MOD_PKA_2	23	29	PF00069	0.461
MOD_PKA_2	248	254	PF00069	0.320
MOD_PKB_1	137	145	PF00069	0.512
MOD_Plk_1	152	158	PF00069	0.605
MOD_Plk_1	175	181	PF00069	0.475
MOD_Plk_1	239	245	PF00069	0.230
MOD_Plk_4	100	106	PF00069	0.482
MOD_Plk_4	69	75	PF00069	0.615
MOD_ProDKin_1	297	303	PF00069	0.348
MOD_ProDKin_1	66	72	PF00069	0.637
TRG_DiLeu_BaLyEn_6	219	224	PF01217	0.479
TRG_ER_diArg_1	127	130	PF00400	0.512
TRG_ER_diArg_1	137	140	PF00400	0.610

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKB7	Leptomonas seymouri	40%	100%
A0A0S4J594	Bodo saltans	26%	86%
A0A1X0NRR5	Trypanosomatidae	28%	97%
A0A422N6N8	Trypanosoma rangeli	25%	100%
C9ZJT7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
V5BA88	Trypanosoma cruzi	25%	100%