RNase III domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

HPP family, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X7A3_LEIDO

TriTrypDb:

LdBPK_340090.1 , LdCL_340006000

Length:

174

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 2, no: 0
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X7A3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X7A3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	111	117	PF00089	0.506
DOC_USP7_MATH_1	152	156	PF00917	0.503
LIG_14-3-3_CanoR_1	114	118	PF00244	0.509
LIG_14-3-3_CanoR_1	151	157	PF00244	0.548
LIG_14-3-3_CanoR_1	60	66	PF00244	0.658
LIG_APCC_ABBA_1	126	131	PF00400	0.544
LIG_APCC_ABBAyCdc20_2	125	131	PF00400	0.542
LIG_BIR_II_1	1	5	PF00653	0.511
LIG_FHA_1	52	58	PF00498	0.495
LIG_FHA_1	7	13	PF00498	0.500
LIG_FHA_1	80	86	PF00498	0.652
LIG_LIR_Apic_2	108	112	PF02991	0.503
LIG_LIR_Gen_1	3	13	PF02991	0.477
LIG_LIR_Gen_1	70	79	PF02991	0.535
LIG_LIR_Nem_3	116	120	PF02991	0.707
LIG_LIR_Nem_3	3	8	PF02991	0.484
LIG_LIR_Nem_3	70	75	PF02991	0.528
LIG_NRBOX	152	158	PF00104	0.509
LIG_NRBOX	41	47	PF00104	0.457
LIG_NRP_CendR_1	173	174	PF00754	0.585
LIG_SH2_CRK	72	76	PF00017	0.526
LIG_SH2_SRC	110	113	PF00017	0.717
LIG_SH2_STAT5	110	113	PF00017	0.717
LIG_SH2_STAT5	44	47	PF00017	0.663
LIG_SUMO_SIM_anti_2	6	12	PF11976	0.469
LIG_TYR_ITIM	115	120	PF00017	0.702
LIG_WRC_WIRS_1	32	37	PF05994	0.500
MOD_CK1_1	113	119	PF00069	0.645
MOD_CK1_1	155	161	PF00069	0.510
MOD_CK1_1	3	9	PF00069	0.480
MOD_CK1_1	30	36	PF00069	0.499
MOD_CK1_1	95	101	PF00069	0.500
MOD_GlcNHglycan	157	160	PF01048	0.522
MOD_GlcNHglycan	17	21	PF01048	0.521
MOD_GSK3_1	27	34	PF00069	0.487
MOD_GSK3_1	51	58	PF00069	0.497
MOD_GSK3_1	91	98	PF00069	0.652
MOD_NEK2_1	105	110	PF00069	0.497
MOD_NEK2_1	147	152	PF00069	0.607
MOD_NEK2_1	157	162	PF00069	0.472
MOD_NEK2_1	35	40	PF00069	0.494
MOD_OFUCOSY	24	31	PF10250	0.485
MOD_PIKK_1	165	171	PF00454	0.546
MOD_PKA_2	113	119	PF00069	0.512
MOD_Plk_1	6	12	PF00069	0.469
MOD_Plk_4	105	111	PF00069	0.495
MOD_Plk_4	152	158	PF00069	0.509
TRG_DiLeu_BaLyEn_6	134	139	PF01217	0.517
TRG_ENDOCYTIC_2	117	120	PF00928	0.709
TRG_ENDOCYTIC_2	72	75	PF00928	0.525
TRG_ER_diArg_1	123	126	PF00400	0.527
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.708

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I9H7	Leishmania infantum	98%	100%