LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7X794_LEIDO
TriTrypDb:
LdBPK_333110.1 * , LdCL_330038400
Length:
112

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X794
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X794

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 101 103 PF00675 0.598
CLV_NRD_NRD_1 66 68 PF00675 0.491
CLV_PCSK_KEX2_1 101 103 PF00082 0.598
CLV_PCSK_SKI1_1 32 36 PF00082 0.457
CLV_PCSK_SKI1_1 44 48 PF00082 0.453
CLV_PCSK_SKI1_1 97 101 PF00082 0.473
DOC_MAPK_MEF2A_6 72 80 PF00069 0.447
DOC_USP7_UBL2_3 68 72 PF12436 0.511
DOC_WW_Pin1_4 14 19 PF00397 0.489
DOC_WW_Pin1_4 44 49 PF00397 0.488
LIG_14-3-3_CanoR_1 22 28 PF00244 0.461
LIG_FHA_2 90 96 PF00498 0.470
LIG_LIR_Gen_1 100 110 PF02991 0.500
LIG_LIR_Nem_3 100 106 PF02991 0.505
LIG_SH2_CRK 103 107 PF00017 0.461
LIG_SH2_GRB2like 103 106 PF00017 0.459
LIG_SH2_SRC 103 106 PF00017 0.459
LIG_SH3_3 2 8 PF00018 0.534
LIG_SUMO_SIM_par_1 51 56 PF11976 0.467
MOD_CDK_SPK_2 46 51 PF00069 0.470
MOD_CDK_SPxxK_3 44 51 PF00069 0.474
MOD_CK1_1 84 90 PF00069 0.462
MOD_CK2_1 89 95 PF00069 0.471
MOD_GlcNHglycan 55 58 PF01048 0.453
MOD_GSK3_1 80 87 PF00069 0.445
MOD_NEK2_1 23 28 PF00069 0.459
MOD_NEK2_1 53 58 PF00069 0.532
MOD_OFUCOSY 81 88 PF10250 0.452
MOD_PKA_1 67 73 PF00069 0.499
MOD_Plk_1 70 76 PF00069 0.495
MOD_Plk_2-3 89 95 PF00069 0.471
MOD_Plk_4 55 61 PF00069 0.557
MOD_ProDKin_1 14 20 PF00069 0.483
MOD_ProDKin_1 44 50 PF00069 0.488
MOD_SUMO_rev_2 89 99 PF00179 0.471
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.460
TRG_DiLeu_BaLyEn_6 48 53 PF01217 0.403
TRG_ENDOCYTIC_2 103 106 PF00928 0.459
TRG_ER_diArg_1 101 103 PF00400 0.470

Homologs

Protein Taxonomy Sequence identity Coverage
A4I9D7 Leishmania infantum 97% 98%
E9AEH5 Leishmania major 83% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS