LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

46 kD virulence factor

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
46 kD virulence factor
Gene product:
46 kD virulence factor
Species:
Leishmania donovani
UniProt:
A0A3S7X767_LEIDO
TriTrypDb:
LdCL_330039500
Length:
153

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X767
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X767

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 146 150 PF00656 0.453
CLV_C14_Caspase3-7 80 84 PF00656 0.450
CLV_PCSK_KEX2_1 147 149 PF00082 0.456
CLV_PCSK_PC1ET2_1 147 149 PF00082 0.456
CLV_PCSK_SKI1_1 11 15 PF00082 0.447
DEG_Nend_UBRbox_2 1 3 PF02207 0.450
DOC_MAPK_gen_1 137 145 PF00069 0.474
DOC_PP1_RVXF_1 135 141 PF00149 0.475
DOC_USP7_MATH_1 119 123 PF00917 0.464
DOC_WW_Pin1_4 96 101 PF00397 0.468
LIG_CSL_BTD_1 97 100 PF09270 0.468
LIG_FHA_1 109 115 PF00498 0.454
LIG_FHA_1 53 59 PF00498 0.459
LIG_PCNA_yPIPBox_3 101 114 PF02747 0.464
LIG_SH3_3 46 52 PF00018 0.449
LIG_SH3_3 94 100 PF00018 0.466
LIG_SUMO_SIM_anti_2 111 117 PF11976 0.452
LIG_TRAF2_1 25 28 PF00917 0.450
MOD_CDK_SPK_2 96 101 PF00069 0.468
MOD_CK1_1 108 114 PF00069 0.455
MOD_CK1_1 122 128 PF00069 0.477
MOD_CK1_1 99 105 PF00069 0.467
MOD_GlcNHglycan 70 73 PF01048 0.404
MOD_GSK3_1 92 99 PF00069 0.471
MOD_NEK2_1 5 10 PF00069 0.435
MOD_PIKK_1 103 109 PF00454 0.470
MOD_ProDKin_1 96 102 PF00069 0.471
MOD_SUMO_rev_2 122 131 PF00179 0.479
TRG_ER_diArg_1 135 138 PF00400 0.475
TRG_ER_diArg_1 9 12 PF00400 0.447

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS