Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X746_LEIDO

TriTrypDb:

LdCL_330037500 , LDHU3_33.4320

Length:

225

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 1
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3S7X746

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X746

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	78	80	PF00675	0.367
CLV_NRD_NRD_1	82	84	PF00675	0.387
CLV_PCSK_FUR_1	76	80	PF00082	0.399
CLV_PCSK_KEX2_1	190	192	PF00082	0.495
CLV_PCSK_KEX2_1	76	78	PF00082	0.518
CLV_PCSK_KEX2_1	82	84	PF00082	0.498
CLV_PCSK_PC1ET2_1	190	192	PF00082	0.456
CLV_PCSK_PC7_1	72	78	PF00082	0.365
CLV_PCSK_SKI1_1	119	123	PF00082	0.496
DEG_MDM2_SWIB_1	66	73	PF02201	0.430
DEG_SPOP_SBC_1	111	115	PF00917	0.669
DEG_SPOP_SBC_1	5	9	PF00917	0.473
DOC_MAPK_RevD_3	63	77	PF00069	0.426
DOC_USP7_MATH_1	121	125	PF00917	0.720
DOC_USP7_MATH_1	16	20	PF00917	0.426
DOC_USP7_MATH_1	189	193	PF00917	0.703
DOC_USP7_MATH_1	23	27	PF00917	0.388
DOC_USP7_MATH_1	5	9	PF00917	0.473
LIG_14-3-3_CanoR_1	144	152	PF00244	0.625
LIG_14-3-3_CanoR_1	191	197	PF00244	0.665
LIG_14-3-3_CanoR_1	205	210	PF00244	0.649
LIG_14-3-3_CanoR_1	82	86	PF00244	0.605
LIG_BIR_III_2	120	124	PF00653	0.647
LIG_FHA_1	103	109	PF00498	0.665
LIG_FHA_1	126	132	PF00498	0.638
LIG_FHA_1	46	52	PF00498	0.396
LIG_FHA_2	113	119	PF00498	0.647
LIG_FHA_2	95	101	PF00498	0.657
LIG_NRBOX	52	58	PF00104	0.283
LIG_NRBOX	64	70	PF00104	0.233
LIG_PDZ_Class_3	220	225	PF00595	0.634
LIG_Pex14_2	66	70	PF04695	0.349
LIG_SH2_STAT5	96	99	PF00017	0.694
LIG_SH3_1	164	170	PF00018	0.661
LIG_SH3_3	164	170	PF00018	0.687
LIG_TRAF2_1	180	183	PF00917	0.718
LIG_TRAF2_1	84	87	PF00917	0.625
LIG_TRAF2_1	97	100	PF00917	0.658
LIG_WRC_WIRS_1	122	127	PF05994	0.539
MOD_CK1_1	124	130	PF00069	0.590
MOD_CK1_1	132	138	PF00069	0.554
MOD_CK1_1	192	198	PF00069	0.548
MOD_CK1_1	216	222	PF00069	0.518
MOD_CK2_1	112	118	PF00069	0.489
MOD_CK2_1	81	87	PF00069	0.506
MOD_CK2_1	94	100	PF00069	0.558
MOD_GlcNHglycan	131	134	PF01048	0.586
MOD_GlcNHglycan	137	140	PF01048	0.561
MOD_GlcNHglycan	42	45	PF01048	0.475
MOD_GSK3_1	102	109	PF00069	0.632
MOD_GSK3_1	121	128	PF00069	0.575
MOD_GSK3_1	201	208	PF00069	0.532
MOD_N-GLC_1	45	50	PF02516	0.397
MOD_NEK2_1	125	130	PF00069	0.532
MOD_NEK2_1	160	165	PF00069	0.562
MOD_NEK2_2	16	21	PF00069	0.534
MOD_PIKK_1	158	164	PF00454	0.550
MOD_PKA_1	190	196	PF00069	0.553
MOD_PKA_2	190	196	PF00069	0.553
MOD_PKA_2	81	87	PF00069	0.486
MOD_PKB_1	199	207	PF00069	0.533
MOD_Plk_1	213	219	PF00069	0.525
MOD_Plk_4	121	127	PF00069	0.576
TRG_ER_diArg_1	196	199	PF00400	0.609
TRG_ER_diArg_1	76	79	PF00400	0.466

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HM00	Leishmania braziliensis	44%	100%