LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

LIM_domain_containing_protein_putative/Pfam:PF004 12

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
LIM_domain_containing_protein_putative/Pfam:PF004 12
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X718_LEIDO
TriTrypDb:
LdBPK_332780.1 , LdCL_330034900 , LDHU3_33.3920
Length:
429

Annotations

Annotations by Jardim et al.

Nucleic acid binding, guide RNA associated 1 Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X718
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X718

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0005488 binding 1 6
GO:0043167 ion binding 2 6
GO:0043169 cation binding 3 6
GO:0046872 metal ion binding 4 6

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 25 29 PF00656 0.663
CLV_C14_Caspase3-7 388 392 PF00656 0.625
CLV_C14_Caspase3-7 92 96 PF00656 0.784
CLV_NRD_NRD_1 247 249 PF00675 0.513
CLV_NRD_NRD_1 268 270 PF00675 0.411
CLV_NRD_NRD_1 333 335 PF00675 0.624
CLV_NRD_NRD_1 370 372 PF00675 0.613
CLV_NRD_NRD_1 411 413 PF00675 0.744
CLV_PCSK_FUR_1 331 335 PF00082 0.655
CLV_PCSK_KEX2_1 174 176 PF00082 0.683
CLV_PCSK_KEX2_1 247 249 PF00082 0.513
CLV_PCSK_KEX2_1 268 270 PF00082 0.411
CLV_PCSK_KEX2_1 333 335 PF00082 0.637
CLV_PCSK_KEX2_1 370 372 PF00082 0.621
CLV_PCSK_KEX2_1 86 88 PF00082 0.641
CLV_PCSK_PC1ET2_1 174 176 PF00082 0.727
CLV_PCSK_PC1ET2_1 86 88 PF00082 0.641
CLV_PCSK_SKI1_1 83 87 PF00082 0.739
DEG_APCC_DBOX_1 222 230 PF00400 0.598
DEG_Nend_UBRbox_2 1 3 PF02207 0.731
DEG_SPOP_SBC_1 102 106 PF00917 0.789
DEG_SPOP_SBC_1 22 26 PF00917 0.624
DOC_MAPK_gen_1 213 220 PF00069 0.580
DOC_MAPK_gen_1 331 340 PF00069 0.677
DOC_USP7_MATH_1 102 106 PF00917 0.787
DOC_USP7_MATH_1 141 145 PF00917 0.698
DOC_USP7_MATH_1 250 254 PF00917 0.411
DOC_USP7_MATH_1 283 287 PF00917 0.411
DOC_USP7_UBL2_3 79 83 PF12436 0.639
DOC_WW_Pin1_4 155 160 PF00397 0.830
DOC_WW_Pin1_4 9 14 PF00397 0.706
DOC_WW_Pin1_4 94 99 PF00397 0.699
LIG_14-3-3_CanoR_1 154 159 PF00244 0.749
LIG_14-3-3_CanoR_1 160 168 PF00244 0.686
LIG_14-3-3_CanoR_1 370 380 PF00244 0.607
LIG_14-3-3_CanoR_1 412 418 PF00244 0.785
LIG_14-3-3_CanoR_1 77 85 PF00244 0.601
LIG_BRCT_BRCA1_1 106 110 PF00533 0.738
LIG_BRCT_BRCA1_1 175 179 PF00533 0.698
LIG_BRCT_BRCA1_1 252 256 PF00533 0.411
LIG_FHA_1 104 110 PF00498 0.754
LIG_FHA_1 123 129 PF00498 0.605
LIG_FHA_1 359 365 PF00498 0.528
LIG_FHA_1 414 420 PF00498 0.735
LIG_FHA_1 42 48 PF00498 0.676
LIG_FHA_1 71 77 PF00498 0.694
LIG_FHA_2 202 208 PF00498 0.578
LIG_FHA_2 310 316 PF00498 0.663
LIG_FHA_2 386 392 PF00498 0.618
LIG_Integrin_RGD_1 313 315 PF01839 0.740
LIG_LIR_Gen_1 184 193 PF02991 0.640
LIG_LIR_Gen_1 315 322 PF02991 0.630
LIG_LIR_Gen_1 377 386 PF02991 0.559
LIG_LIR_Nem_3 184 190 PF02991 0.698
LIG_MLH1_MIPbox_1 252 256 PF16413 0.411
LIG_SH2_CRK 187 191 PF00017 0.679
LIG_SH2_CRK 202 206 PF00017 0.502
LIG_SH2_CRK 222 226 PF00017 0.355
LIG_SH2_NCK_1 187 191 PF00017 0.631
LIG_SH2_STAP1 136 140 PF00017 0.797
LIG_SH2_STAP1 187 191 PF00017 0.631
LIG_SH2_STAP1 293 297 PF00017 0.584
LIG_SH2_STAT3 386 389 PF00017 0.608
LIG_SH2_STAT5 227 230 PF00017 0.665
LIG_SH2_STAT5 264 267 PF00017 0.359
LIG_SH2_STAT5 387 390 PF00017 0.548
LIG_SH3_2 242 247 PF14604 0.513
LIG_SH3_3 147 153 PF00018 0.703
LIG_SH3_3 229 235 PF00018 0.572
LIG_SH3_3 239 245 PF00018 0.362
LIG_SH3_3 51 57 PF00018 0.753
LIG_SH3_3 7 13 PF00018 0.704
LIG_TRAF2_1 298 301 PF00917 0.594
LIG_TRAF2_2 13 18 PF00917 0.701
MOD_CDK_SPK_2 155 160 PF00069 0.745
MOD_CK1_1 104 110 PF00069 0.754
MOD_CK1_1 111 117 PF00069 0.745
MOD_CK1_1 144 150 PF00069 0.712
MOD_CK1_1 194 200 PF00069 0.688
MOD_CK1_1 374 380 PF00069 0.672
MOD_CK2_1 201 207 PF00069 0.578
MOD_Cter_Amidation 266 269 PF01082 0.389
MOD_Cter_Amidation 410 413 PF01082 0.736
MOD_GlcNHglycan 137 140 PF01048 0.755
MOD_GlcNHglycan 143 146 PF01048 0.711
MOD_GlcNHglycan 163 166 PF01048 0.639
MOD_GlcNHglycan 193 196 PF01048 0.678
MOD_GlcNHglycan 25 28 PF01048 0.706
MOD_GlcNHglycan 30 33 PF01048 0.693
MOD_GlcNHglycan 35 38 PF01048 0.651
MOD_GlcNHglycan 373 376 PF01048 0.658
MOD_GlcNHglycan 400 403 PF01048 0.715
MOD_GlcNHglycan 424 427 PF01048 0.595
MOD_GlcNHglycan 80 83 PF01048 0.730
MOD_GlcNHglycan 98 101 PF01048 0.589
MOD_GSK3_1 104 111 PF00069 0.790
MOD_GSK3_1 14 21 PF00069 0.803
MOD_GSK3_1 155 162 PF00069 0.807
MOD_GSK3_1 334 341 PF00069 0.777
MOD_GSK3_1 370 377 PF00069 0.566
MOD_LATS_1 368 374 PF00433 0.616
MOD_N-GLC_1 114 119 PF02516 0.700
MOD_N-GLC_1 185 190 PF02516 0.640
MOD_N-GLC_1 371 376 PF02516 0.690
MOD_N-GLC_2 237 239 PF02516 0.490
MOD_NEK2_1 108 113 PF00069 0.744
MOD_NEK2_2 250 255 PF00069 0.411
MOD_PIKK_1 108 114 PF00454 0.729
MOD_PIKK_1 11 17 PF00454 0.696
MOD_PIKK_1 385 391 PF00454 0.601
MOD_PK_1 404 410 PF00069 0.594
MOD_PKA_1 370 376 PF00069 0.522
MOD_PKA_1 412 418 PF00069 0.689
MOD_PKA_2 153 159 PF00069 0.788
MOD_PKA_2 267 273 PF00069 0.513
MOD_PKA_2 370 376 PF00069 0.566
MOD_PKA_2 421 427 PF00069 0.807
MOD_Plk_1 185 191 PF00069 0.713
MOD_Plk_4 104 110 PF00069 0.767
MOD_Plk_4 186 192 PF00069 0.611
MOD_Plk_4 250 256 PF00069 0.411
MOD_Plk_4 46 52 PF00069 0.704
MOD_ProDKin_1 155 161 PF00069 0.825
MOD_ProDKin_1 9 15 PF00069 0.707
MOD_ProDKin_1 94 100 PF00069 0.697
MOD_SUMO_for_1 85 88 PF00179 0.701
TRG_ENDOCYTIC_2 187 190 PF00928 0.688
TRG_ENDOCYTIC_2 202 205 PF00928 0.496
TRG_ENDOCYTIC_2 276 279 PF00928 0.364
TRG_ENDOCYTIC_2 317 320 PF00928 0.565
TRG_ER_diArg_1 212 215 PF00400 0.609
TRG_ER_diArg_1 246 248 PF00400 0.513
TRG_ER_diArg_1 331 334 PF00400 0.722

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCS1 Leptomonas seymouri 54% 100%
A4HLX5 Leishmania braziliensis 65% 99%
A4I9A4 Leishmania infantum 100% 100%
E9B4A4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%
Q4Q3S2 Leishmania major 88% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS