LeishMANIAdb
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Serine/threonine protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Serine/threonine protein kinase
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7X6U0_LEIDO
TriTrypDb:
LdCL_330024600 , LDHU3_33.2650
Length:
113

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X6U0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X6U0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 104 106 PF00675 0.650
CLV_NRD_NRD_1 69 71 PF00675 0.430
CLV_NRD_NRD_1 92 94 PF00675 0.455
CLV_PCSK_FUR_1 67 71 PF00082 0.520
CLV_PCSK_KEX2_1 69 71 PF00082 0.429
CLV_PCSK_SKI1_1 93 97 PF00082 0.424
DEG_APCC_DBOX_1 92 100 PF00400 0.421
DEG_Nend_Nbox_1 1 3 PF02207 0.390
DOC_MAPK_MEF2A_6 34 41 PF00069 0.432
DOC_MAPK_MEF2A_6 48 57 PF00069 0.431
DOC_MAPK_NFAT4_5 34 42 PF00069 0.435
DOC_WW_Pin1_4 105 110 PF00397 0.645
LIG_FHA_1 14 20 PF00498 0.511
LIG_FHA_1 34 40 PF00498 0.368
LIG_FHA_1 63 69 PF00498 0.510
LIG_FHA_2 45 51 PF00498 0.497
LIG_LIR_Gen_1 72 83 PF02991 0.503
LIG_LIR_Nem_3 72 78 PF02991 0.453
MOD_CK1_1 88 94 PF00069 0.520
MOD_CK2_1 44 50 PF00069 0.482
MOD_GlcNHglycan 90 93 PF01048 0.490
MOD_NEK2_1 1 6 PF00069 0.472
MOD_PIKK_1 57 63 PF00454 0.317
MOD_PK_1 70 76 PF00069 0.481
MOD_Plk_1 70 76 PF00069 0.505
MOD_Plk_4 70 76 PF00069 0.505
MOD_ProDKin_1 105 111 PF00069 0.650
TRG_DiLeu_BaLyEn_6 107 112 PF01217 0.665
TRG_DiLeu_BaLyEn_6 35 40 PF01217 0.430
TRG_ER_diArg_1 67 70 PF00400 0.407
TRG_Pf-PMV_PEXEL_1 56 61 PF00026 0.493

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PFW7 Leptomonas seymouri 68% 93%
A0A1X0P2P8 Trypanosomatidae 37% 99%
A0A3R7LLI7 Trypanosoma rangeli 38% 99%
C9ZIV9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 38% 98%
V5AXF2 Trypanosoma cruzi 37% 86%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS