RNA binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X6N3_LEIDO

TriTrypDb:

LdBPK_331530.1 , LdCL_330021900 , LDHU3_33.2290

Length:

678

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X6N3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X6N3

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	6
GO:0003723	RNA binding	4	6
GO:0005488	binding	1	6
GO:0097159	organic cyclic compound binding	2	6
GO:1901363	heterocyclic compound binding	2	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	38	42	PF00656	0.643
CLV_C14_Caspase3-7	383	387	PF00656	0.692
CLV_C14_Caspase3-7	627	631	PF00656	0.599
CLV_NRD_NRD_1	205	207	PF00675	0.566
CLV_NRD_NRD_1	530	532	PF00675	0.639
CLV_NRD_NRD_1	591	593	PF00675	0.661
CLV_PCSK_KEX2_1	205	207	PF00082	0.566
CLV_PCSK_KEX2_1	530	532	PF00082	0.639
CLV_PCSK_PC7_1	526	532	PF00082	0.623
CLV_PCSK_SKI1_1	261	265	PF00082	0.596
CLV_PCSK_SKI1_1	520	524	PF00082	0.706
CLV_PCSK_SKI1_1	535	539	PF00082	0.382
CLV_PCSK_SKI1_1	573	577	PF00082	0.345
DEG_Nend_Nbox_1	1	3	PF02207	0.606
DEG_SPOP_SBC_1	235	239	PF00917	0.650
DEG_SPOP_SBC_1	319	323	PF00917	0.637
DEG_SPOP_SBC_1	97	101	PF00917	0.631
DOC_CKS1_1	11	16	PF01111	0.630
DOC_CKS1_1	353	358	PF01111	0.643
DOC_MAPK_DCC_7	661	670	PF00069	0.513
DOC_MAPK_gen_1	530	540	PF00069	0.634
DOC_MAPK_MEF2A_6	160	168	PF00069	0.546
DOC_MAPK_MEF2A_6	661	670	PF00069	0.513
DOC_PP1_RVXF_1	163	169	PF00149	0.604
DOC_PP1_RVXF_1	533	540	PF00149	0.511
DOC_USP7_MATH_1	175	179	PF00917	0.650
DOC_USP7_MATH_1	190	194	PF00917	0.588
DOC_USP7_MATH_1	21	25	PF00917	0.673
DOC_USP7_MATH_1	235	239	PF00917	0.650
DOC_USP7_MATH_1	290	294	PF00917	0.724
DOC_USP7_MATH_1	298	302	PF00917	0.693
DOC_USP7_MATH_1	319	323	PF00917	0.679
DOC_USP7_MATH_1	35	39	PF00917	0.642
DOC_USP7_MATH_1	397	401	PF00917	0.769
DOC_USP7_MATH_1	479	483	PF00917	0.669
DOC_USP7_MATH_1	550	554	PF00917	0.619
DOC_USP7_MATH_1	98	102	PF00917	0.646
DOC_USP7_UBL2_3	569	573	PF12436	0.559
DOC_WW_Pin1_4	10	15	PF00397	0.624
DOC_WW_Pin1_4	134	139	PF00397	0.695
DOC_WW_Pin1_4	171	176	PF00397	0.631
DOC_WW_Pin1_4	221	226	PF00397	0.659
DOC_WW_Pin1_4	242	247	PF00397	0.718
DOC_WW_Pin1_4	352	357	PF00397	0.693
DOC_WW_Pin1_4	426	431	PF00397	0.586
LIG_14-3-3_CanoR_1	206	215	PF00244	0.620
LIG_14-3-3_CanoR_1	216	220	PF00244	0.617
LIG_14-3-3_CanoR_1	233	241	PF00244	0.498
LIG_14-3-3_CanoR_1	261	271	PF00244	0.603
LIG_14-3-3_CanoR_1	514	522	PF00244	0.711
LIG_BRCT_BRCA1_1	552	556	PF00533	0.559
LIG_deltaCOP1_diTrp_1	79	87	PF00928	0.580
LIG_FHA_1	121	127	PF00498	0.675
LIG_FHA_1	216	222	PF00498	0.673
LIG_FHA_1	304	310	PF00498	0.649
LIG_FHA_1	340	346	PF00498	0.586
LIG_FHA_1	348	354	PF00498	0.587
LIG_FHA_1	370	376	PF00498	0.715
LIG_FHA_1	523	529	PF00498	0.607
LIG_FHA_1	608	614	PF00498	0.415
LIG_FHA_1	641	647	PF00498	0.549
LIG_FHA_2	546	552	PF00498	0.559
LIG_FHA_2	602	608	PF00498	0.500
LIG_LIR_Apic_2	482	488	PF02991	0.767
LIG_LIR_Apic_2	557	562	PF02991	0.559
LIG_LIR_Gen_1	306	314	PF02991	0.668
LIG_LIR_Gen_1	429	436	PF02991	0.594
LIG_LIR_Gen_1	632	639	PF02991	0.490
LIG_LIR_Gen_1	85	96	PF02991	0.653
LIG_LIR_Nem_3	265	271	PF02991	0.682
LIG_LIR_Nem_3	429	435	PF02991	0.596
LIG_LIR_Nem_3	553	559	PF02991	0.598
LIG_LIR_Nem_3	597	602	PF02991	0.497
LIG_LIR_Nem_3	632	637	PF02991	0.508
LIG_LIR_Nem_3	85	91	PF02991	0.658
LIG_MYND_1	23	27	PF01753	0.648
LIG_Pex14_2	255	259	PF04695	0.538
LIG_Pex14_2	87	91	PF04695	0.660
LIG_PTB_Apo_2	628	635	PF02174	0.525
LIG_PTB_Phospho_1	628	634	PF10480	0.540
LIG_SH2_CRK	432	436	PF00017	0.630
LIG_SH2_CRK	559	563	PF00017	0.587
LIG_SH2_SRC	374	377	PF00017	0.723
LIG_SH2_STAP1	271	275	PF00017	0.625
LIG_SH2_STAP1	432	436	PF00017	0.546
LIG_SH2_STAT3	410	413	PF00017	0.680
LIG_SH2_STAT3	496	499	PF00017	0.655
LIG_SH2_STAT3	639	642	PF00017	0.502
LIG_SH2_STAT5	120	123	PF00017	0.523
LIG_SH2_STAT5	291	294	PF00017	0.656
LIG_SH2_STAT5	374	377	PF00017	0.723
LIG_SH2_STAT5	410	413	PF00017	0.728
LIG_SH2_STAT5	634	637	PF00017	0.581
LIG_SH3_3	169	175	PF00018	0.664
LIG_SH3_3	20	26	PF00018	0.597
LIG_SH3_3	278	284	PF00018	0.687
LIG_SH3_3	308	314	PF00018	0.671
LIG_SH3_3	350	356	PF00018	0.610
LIG_SH3_3	400	406	PF00018	0.719
LIG_SH3_3	5	11	PF00018	0.676
LIG_SH3_3	659	665	PF00018	0.588
LIG_SUMO_SIM_anti_2	330	335	PF11976	0.647
LIG_SUMO_SIM_anti_2	564	570	PF11976	0.559
LIG_SUMO_SIM_par_1	564	570	PF11976	0.559
LIG_SxIP_EBH_1	389	402	PF03271	0.677
LIG_TRAF2_1	147	150	PF00917	0.608
LIG_TRAF2_1	76	79	PF00917	0.667
LIG_TRFH_1	410	414	PF08558	0.678
MOD_CDK_SPxxK_3	10	17	PF00069	0.636
MOD_CK1_1	134	140	PF00069	0.566
MOD_CK1_1	182	188	PF00069	0.686
MOD_CK1_1	208	214	PF00069	0.654
MOD_CK1_1	262	268	PF00069	0.607
MOD_CK1_1	293	299	PF00069	0.683
MOD_CK1_1	300	306	PF00069	0.715
MOD_CK1_1	366	372	PF00069	0.693
MOD_CK1_1	391	397	PF00069	0.772
MOD_CK1_1	447	453	PF00069	0.667
MOD_CK1_1	468	474	PF00069	0.708
MOD_CK1_1	584	590	PF00069	0.634
MOD_CK2_1	601	607	PF00069	0.503
MOD_CK2_1	657	663	PF00069	0.530
MOD_GlcNHglycan	100	103	PF01048	0.706
MOD_GlcNHglycan	134	137	PF01048	0.670
MOD_GlcNHglycan	207	210	PF01048	0.693
MOD_GlcNHglycan	221	224	PF01048	0.614
MOD_GlcNHglycan	238	241	PF01048	0.521
MOD_GlcNHglycan	27	30	PF01048	0.637
MOD_GlcNHglycan	274	278	PF01048	0.777
MOD_GlcNHglycan	292	295	PF01048	0.679
MOD_GlcNHglycan	315	318	PF01048	0.678
MOD_GlcNHglycan	367	371	PF01048	0.728
MOD_GlcNHglycan	46	49	PF01048	0.481
MOD_GlcNHglycan	473	476	PF01048	0.589
MOD_GlcNHglycan	481	484	PF01048	0.634
MOD_GlcNHglycan	516	519	PF01048	0.691
MOD_GlcNHglycan	583	586	PF01048	0.741
MOD_GlcNHglycan	596	599	PF01048	0.463
MOD_GlcNHglycan	646	649	PF01048	0.439
MOD_GlcNHglycan	65	68	PF01048	0.674
MOD_GlcNHglycan	93	96	PF01048	0.629
MOD_GSK3_1	121	128	PF00069	0.658
MOD_GSK3_1	151	158	PF00069	0.644
MOD_GSK3_1	171	178	PF00069	0.542
MOD_GSK3_1	207	214	PF00069	0.706
MOD_GSK3_1	21	28	PF00069	0.684
MOD_GSK3_1	215	222	PF00069	0.634
MOD_GSK3_1	250	257	PF00069	0.625
MOD_GSK3_1	259	266	PF00069	0.540
MOD_GSK3_1	269	276	PF00069	0.519
MOD_GSK3_1	293	300	PF00069	0.628
MOD_GSK3_1	320	327	PF00069	0.646
MOD_GSK3_1	388	395	PF00069	0.728
MOD_GSK3_1	42	49	PF00069	0.636
MOD_GSK3_1	426	433	PF00069	0.689
MOD_GSK3_1	440	447	PF00069	0.647
MOD_GSK3_1	550	557	PF00069	0.604
MOD_GSK3_1	59	66	PF00069	0.658
MOD_GSK3_1	594	601	PF00069	0.527
MOD_GSK3_1	640	647	PF00069	0.576
MOD_GSK3_1	671	678	PF00069	0.569
MOD_GSK3_1	82	89	PF00069	0.707
MOD_GSK3_1	98	105	PF00069	0.548
MOD_LATS_1	203	209	PF00433	0.659
MOD_N-GLC_1	179	184	PF02516	0.718
MOD_N-GLC_1	440	445	PF02516	0.636
MOD_NEK2_1	121	126	PF00069	0.663
MOD_NEK2_1	152	157	PF00069	0.623
MOD_NEK2_1	176	181	PF00069	0.659
MOD_NEK2_1	219	224	PF00069	0.637
MOD_NEK2_1	254	259	PF00069	0.657
MOD_NEK2_1	263	268	PF00069	0.544
MOD_NEK2_1	388	393	PF00069	0.528
MOD_NEK2_1	635	640	PF00069	0.519
MOD_NEK2_1	657	662	PF00069	0.511
MOD_NEK2_1	87	92	PF00069	0.649
MOD_NEK2_2	102	107	PF00069	0.663
MOD_PIKK_1	182	188	PF00454	0.698
MOD_PIKK_1	298	304	PF00454	0.697
MOD_PIKK_1	413	419	PF00454	0.636
MOD_PIKK_1	550	556	PF00454	0.559
MOD_PK_1	561	567	PF00069	0.559
MOD_PKA_1	205	211	PF00069	0.561
MOD_PKA_2	205	211	PF00069	0.610
MOD_PKA_2	215	221	PF00069	0.635
MOD_PKA_2	339	345	PF00069	0.677
MOD_Plk_1	440	446	PF00069	0.607
MOD_Plk_1	550	556	PF00069	0.578
MOD_Plk_2-3	492	498	PF00069	0.661
MOD_Plk_4	121	127	PF00069	0.658
MOD_Plk_4	250	256	PF00069	0.586
MOD_Plk_4	305	311	PF00069	0.721
MOD_Plk_4	327	333	PF00069	0.650
MOD_Plk_4	35	41	PF00069	0.708
MOD_Plk_4	458	464	PF00069	0.684
MOD_Plk_4	46	52	PF00069	0.578
MOD_Plk_4	561	567	PF00069	0.570
MOD_ProDKin_1	10	16	PF00069	0.630
MOD_ProDKin_1	134	140	PF00069	0.692
MOD_ProDKin_1	171	177	PF00069	0.632
MOD_ProDKin_1	221	227	PF00069	0.658
MOD_ProDKin_1	242	248	PF00069	0.718
MOD_ProDKin_1	352	358	PF00069	0.694
MOD_ProDKin_1	426	432	PF00069	0.587
TRG_DiLeu_BaLyEn_6	664	669	PF01217	0.497
TRG_ENDOCYTIC_2	173	176	PF00928	0.696
TRG_ENDOCYTIC_2	198	201	PF00928	0.562
TRG_ENDOCYTIC_2	2	5	PF00928	0.603
TRG_ENDOCYTIC_2	307	310	PF00928	0.689
TRG_ENDOCYTIC_2	432	435	PF00928	0.606
TRG_ENDOCYTIC_2	634	637	PF00928	0.483
TRG_ENDOCYTIC_2	88	91	PF00928	0.660
TRG_ER_diArg_1	205	207	PF00400	0.566
TRG_ER_diArg_1	530	533	PF00400	0.636

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HLK5	Leishmania braziliensis	58%	98%
A4I916	Leishmania infantum	99%	100%
E9B3Y1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	97%
Q4Q443	Leishmania major	86%	100%