ATPase family associated with various cellular activities (AAA)/AAA domain (Dynein-related subfamily), putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATPase family associated with various cellular activities (AAA), putative

Species:

Leishmania donovani

UniProt:

A0A3S7X6K2_LEIDO

TriTrypDb:

LdBPK_331260.1 , LdCL_330018800 , LDHU3_33.1910

Length:

656

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

Previous1Next

Expansion

Sequence features

A0A3S7X6K2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X6K2

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	17
GO:0003824	catalytic activity	1	17
GO:0005488	binding	1	17
GO:0005524	ATP binding	5	17
GO:0016462	pyrophosphatase activity	5	17
GO:0016787	hydrolase activity	2	17
GO:0016817	hydrolase activity, acting on acid anhydrides	3	17
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	17
GO:0016887	ATP hydrolysis activity	7	17
GO:0017076	purine nucleotide binding	4	17

Previous1 2 3Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	112	116	PF00656	0.658
CLV_C14_Caspase3-7	381	385	PF00656	0.741
CLV_C14_Caspase3-7	410	414	PF00656	0.505
CLV_C14_Caspase3-7	455	459	PF00656	0.784
CLV_C14_Caspase3-7	58	62	PF00656	0.598
CLV_NRD_NRD_1	261	263	PF00675	0.471
CLV_NRD_NRD_1	439	441	PF00675	0.543
CLV_PCSK_FUR_1	437	441	PF00082	0.589
CLV_PCSK_KEX2_1	261	263	PF00082	0.499
CLV_PCSK_KEX2_1	351	353	PF00082	0.285

Previous1 2 3 4 5…24Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P4V2	Leptomonas seymouri	59%	98%
A0A0S4JAD3	Bodo saltans	32%	100%
A0A1X0NTT2	Trypanosomatidae	28%	97%
A0A1X0P2Y3	Trypanosomatidae	28%	100%
A0A1X0P9I4	Trypanosomatidae	29%	81%
A0A422NUH1	Trypanosoma rangeli	29%	97%
A0A422P3P3	Trypanosoma rangeli	30%	100%
A4HLH5	Leishmania braziliensis	73%	96%
A4I8Y5	Leishmania infantum	100%	100%
C9ZQW4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%

Previous1 2Next