Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X6A8_LEIDO

TriTrypDb:

LdCL_330009700 , LDHU3_33.0660

Length:

231

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3S7X6A8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X6A8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	90	92	PF00675	0.362
CLV_PCSK_KEX2_1	90	92	PF00082	0.362
DEG_SCF_FBW7_1	174	179	PF00400	0.558
DEG_SPOP_SBC_1	9	13	PF00917	0.402
DOC_CKS1_1	173	178	PF01111	0.551
DOC_CYCLIN_yCln2_LP_2	110	116	PF00134	0.555
DOC_MAPK_gen_1	90	98	PF00069	0.581
DOC_PP2B_LxvP_1	110	113	PF13499	0.561
DOC_USP7_MATH_1	133	137	PF00917	0.537
DOC_USP7_MATH_1	182	186	PF00917	0.709
DOC_USP7_MATH_1	191	195	PF00917	0.600
DOC_USP7_MATH_1	24	28	PF00917	0.413
DOC_USP7_MATH_1	76	80	PF00917	0.266
DOC_USP7_MATH_1	9	13	PF00917	0.402
DOC_USP7_MATH_1	97	101	PF00917	0.584
DOC_WW_Pin1_4	172	177	PF00397	0.584
DOC_WW_Pin1_4	53	58	PF00397	0.361
LIG_14-3-3_CanoR_1	204	210	PF00244	0.565
LIG_14-3-3_CanoR_1	45	50	PF00244	0.393
LIG_BIR_III_2	15	19	PF00653	0.395
LIG_BRCT_BRCA1_1	57	61	PF00533	0.359
LIG_DLG_GKlike_1	45	52	PF00625	0.392
LIG_FHA_1	204	210	PF00498	0.612
LIG_FHA_1	30	36	PF00498	0.402
LIG_LYPXL_yS_3	132	135	PF13949	0.535
LIG_SH2_CRK	130	134	PF00017	0.543
LIG_SH2_SRC	130	133	PF00017	0.555
LIG_SH3_3	139	145	PF00018	0.535
LIG_SH3_3	15	21	PF00018	0.419
LIG_SH3_3	210	216	PF00018	0.572
LIG_Sin3_3	92	99	PF02671	0.581
LIG_SUMO_SIM_anti_2	39	45	PF11976	0.391
LIG_SUMO_SIM_par_1	94	100	PF11976	0.716
LIG_WRC_WIRS_1	52	57	PF05994	0.363
MOD_CK1_1	105	111	PF00069	0.730
MOD_CK1_1	205	211	PF00069	0.644
MOD_CK1_1	48	54	PF00069	0.401
MOD_GlcNHglycan	184	187	PF01048	0.480
MOD_GlcNHglycan	209	212	PF01048	0.402
MOD_GlcNHglycan	218	221	PF01048	0.301
MOD_GlcNHglycan	32	35	PF01048	0.593
MOD_GlcNHglycan	57	60	PF01048	0.693
MOD_GlcNHglycan	64	67	PF01048	0.570
MOD_GlcNHglycan	99	102	PF01048	0.362
MOD_GSK3_1	102	109	PF00069	0.564
MOD_GSK3_1	172	179	PF00069	0.555
MOD_GSK3_1	182	189	PF00069	0.581
MOD_GSK3_1	199	206	PF00069	0.519
MOD_GSK3_1	24	31	PF00069	0.421
MOD_GSK3_1	51	58	PF00069	0.475
MOD_N-GLC_1	222	227	PF02516	0.300
MOD_N-GLC_2	121	123	PF02516	0.325
MOD_NEK2_1	106	111	PF00069	0.563
MOD_NEK2_2	199	204	PF00069	0.590
MOD_OFUCOSY	188	195	PF10250	0.346
MOD_OFUCOSY	198	203	PF10250	0.363
MOD_PIKK_1	133	139	PF00454	0.538
MOD_PIKK_1	85	91	PF00454	0.433
MOD_PKA_2	203	209	PF00069	0.561
MOD_Plk_1	222	228	PF00069	0.495
MOD_Plk_1	59	65	PF00069	0.430
MOD_Plk_4	102	108	PF00069	0.621
MOD_Plk_4	148	154	PF00069	0.597
MOD_Plk_4	222	228	PF00069	0.541
MOD_Plk_4	39	45	PF00069	0.431
MOD_Plk_4	48	54	PF00069	0.352
MOD_Plk_4	76	82	PF00069	0.237
MOD_ProDKin_1	172	178	PF00069	0.585
MOD_ProDKin_1	53	59	PF00069	0.361
TRG_ENDOCYTIC_2	132	135	PF00928	0.535

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8B4	Leptomonas seymouri	52%	88%