LeishMANIAdb
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RGG-containing protein 2, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RGG-containing protein 2, putative
Gene product:
RGG-containing protein 2, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X6A5_LEIDO
TriTrypDb:
LdBPK_330280.1 * , LdCL_330007700 , LDHU3_33.0330
Length:
339

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
TermNameLevelCount
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0005739 mitochondrion 5 1
GO:0020023 kinetoplast 2 1
GO:0032473 cytoplasmic side of mitochondrial outer membrane 4 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0098552 side of membrane 2 1
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Expansion

Sequence features

A0A3S7X6A5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X6A5

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 5
GO:0003723 RNA binding 4 5
GO:0003729 mRNA binding 5 1
GO:0005488 binding 1 5
GO:0097159 organic cyclic compound binding 2 5
GO:1901363 heterocyclic compound binding 2 5
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 124 128 PF00656 0.845
CLV_C14_Caspase3-7 304 308 PF00656 0.702
CLV_C14_Caspase3-7 44 48 PF00656 0.561
CLV_C14_Caspase3-7 56 60 PF00656 0.558
CLV_C14_Caspase3-7 92 96 PF00656 0.564
CLV_NRD_NRD_1 163 165 PF00675 0.841
CLV_NRD_NRD_1 197 199 PF00675 0.796
CLV_NRD_NRD_1 299 301 PF00675 0.619
CLV_NRD_NRD_1 3 5 PF00675 0.783
CLV_NRD_NRD_1 312 314 PF00675 0.509
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Homologs

ProteinTaxonomySequence identityCoverage
A4I8P4 Leishmania infantum 96% 96%
E9B3K5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 96%
Q4Q4J4 Leishmania major 92% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS