A conserved kinetoplastid protein with N-terminal signal-anchor and an ankyrin repeat domain. The latter is related to the domain found in eukaryotic peptidyl-prolyl isomerases.
Uncharacterized Protein, Uncharacterized
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 0 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 7 |
| NetGPI | no | yes: 0, no: 7 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0032991 | protein-containing complex | 1 | 1 |
| GO:0101031 | protein folding chaperone complex | 3 | 1 |
| GO:0140535 | intracellular protein-containing complex | 2 | 1 |
| GO:0016020 | membrane | 2 | 1 |
| GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: A0A3S7X657
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 179 | 181 | PF00675 | 0.634 |
| CLV_NRD_NRD_1 | 39 | 41 | PF00675 | 0.729 |
| CLV_PCSK_KEX2_1 | 179 | 181 | PF00082 | 0.634 |
| DEG_Nend_UBRbox_3 | 1 | 3 | PF02207 | 0.767 |
| DOC_MAPK_gen_1 | 82 | 91 | PF00069 | 0.550 |
| DOC_MAPK_RevD_3 | 164 | 180 | PF00069 | 0.555 |
| DOC_USP7_MATH_1 | 42 | 46 | PF00917 | 0.544 |
| DOC_USP7_MATH_1 | 58 | 62 | PF00917 | 0.392 |
| DOC_WW_Pin1_4 | 44 | 49 | PF00397 | 0.529 |
| DOC_WW_Pin1_4 | 59 | 64 | PF00397 | 0.441 |
| DOC_WW_Pin1_4 | 72 | 77 | PF00397 | 0.593 |
| LIG_14-3-3_CanoR_1 | 154 | 160 | PF00244 | 0.462 |
| LIG_14-3-3_CanoR_1 | 28 | 37 | PF00244 | 0.469 |
| LIG_14-3-3_CanoR_1 | 4 | 11 | PF00244 | 0.560 |
| LIG_FHA_1 | 10 | 16 | PF00498 | 0.433 |
| LIG_FHA_1 | 117 | 123 | PF00498 | 0.456 |
| LIG_FHA_1 | 130 | 136 | PF00498 | 0.467 |
| LIG_FHA_1 | 156 | 162 | PF00498 | 0.455 |
| LIG_LIR_Nem_3 | 23 | 27 | PF02991 | 0.416 |
| LIG_RPA_C_Fungi | 175 | 187 | PF08784 | 0.607 |
| LIG_SH2_CRK | 27 | 31 | PF00017 | 0.736 |
| LIG_SH3_3 | 45 | 51 | PF00018 | 0.770 |
| LIG_SH3_3 | 62 | 68 | PF00018 | 0.550 |
| LIG_SH3_3 | 70 | 76 | PF00018 | 0.717 |
| LIG_SUMO_SIM_anti_2 | 215 | 220 | PF11976 | 0.602 |
| LIG_TRAF2_1 | 99 | 102 | PF00917 | 0.587 |
| LIG_UBA3_1 | 88 | 93 | PF00899 | 0.550 |
| MOD_CK1_1 | 31 | 37 | PF00069 | 0.627 |
| MOD_GlcNHglycan | 33 | 36 | PF01048 | 0.689 |
| MOD_PIKK_1 | 28 | 34 | PF00454 | 0.707 |
| MOD_PIKK_1 | 3 | 9 | PF00454 | 0.697 |
| MOD_PKA_2 | 3 | 9 | PF00069 | 0.697 |
| MOD_Plk_1 | 116 | 122 | PF00069 | 0.628 |
| MOD_Plk_4 | 117 | 123 | PF00069 | 0.681 |
| MOD_Plk_4 | 155 | 161 | PF00069 | 0.634 |
| MOD_Plk_4 | 9 | 15 | PF00069 | 0.401 |
| MOD_ProDKin_1 | 44 | 50 | PF00069 | 0.671 |
| MOD_ProDKin_1 | 59 | 65 | PF00069 | 0.548 |
| MOD_ProDKin_1 | 72 | 78 | PF00069 | 0.759 |
| MOD_SUMO_rev_2 | 170 | 174 | PF00179 | 0.646 |
| MOD_SUMO_rev_2 | 34 | 42 | PF00179 | 0.754 |
| TRG_ENDOCYTIC_2 | 27 | 30 | PF00928 | 0.731 |
| TRG_ER_diArg_1 | 178 | 180 | PF00400 | 0.571 |
| TRG_Pf-PMV_PEXEL_1 | 28 | 32 | PF00026 | 0.743 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1PAP4 | Leptomonas seymouri | 51% | 100% |
| A0A1X0NTN3 | Trypanosomatidae | 50% | 100% |
| A4HL17 | Leishmania braziliensis | 79% | 100% |
| A4I8J8 | Leishmania infantum | 100% | 100% |
| E9B3F8 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 92% | 100% |
| Q4Q4P2 | Leishmania major | 95% | 100% |