Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X5W9_LEIDO

TriTrypDb:

LdBPK_322910.1 , LdCL_320035100 , LDHU3_32.3690

Length:

956

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X5W9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5W9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	244	248	PF00656	0.713
CLV_C14_Caspase3-7	870	874	PF00656	0.619
CLV_C14_Caspase3-7	920	924	PF00656	0.607
CLV_NRD_NRD_1	153	155	PF00675	0.716
CLV_NRD_NRD_1	173	175	PF00675	0.333
CLV_NRD_NRD_1	268	270	PF00675	0.694
CLV_NRD_NRD_1	307	309	PF00675	0.613
CLV_NRD_NRD_1	418	420	PF00675	0.741
CLV_NRD_NRD_1	449	451	PF00675	0.838
CLV_NRD_NRD_1	521	523	PF00675	0.807
CLV_NRD_NRD_1	624	626	PF00675	0.751
CLV_NRD_NRD_1	662	664	PF00675	0.758
CLV_NRD_NRD_1	783	785	PF00675	0.723
CLV_NRD_NRD_1	943	945	PF00675	0.689
CLV_PCSK_FUR_1	174	178	PF00082	0.625
CLV_PCSK_FUR_1	194	198	PF00082	0.392
CLV_PCSK_FUR_1	305	309	PF00082	0.610
CLV_PCSK_KEX2_1	153	155	PF00082	0.716
CLV_PCSK_KEX2_1	173	175	PF00082	0.333
CLV_PCSK_KEX2_1	176	178	PF00082	0.613
CLV_PCSK_KEX2_1	196	198	PF00082	0.446
CLV_PCSK_KEX2_1	268	270	PF00082	0.694
CLV_PCSK_KEX2_1	307	309	PF00082	0.613
CLV_PCSK_KEX2_1	420	422	PF00082	0.798
CLV_PCSK_KEX2_1	449	451	PF00082	0.838
CLV_PCSK_KEX2_1	662	664	PF00082	0.755
CLV_PCSK_KEX2_1	667	669	PF00082	0.750
CLV_PCSK_KEX2_1	783	785	PF00082	0.723
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.593
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.479
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.798
CLV_PCSK_PC1ET2_1	667	669	PF00082	0.795
CLV_PCSK_PC7_1	303	309	PF00082	0.608
CLV_PCSK_PC7_1	663	669	PF00082	0.692
CLV_PCSK_SKI1_1	173	177	PF00082	0.558
CLV_PCSK_SKI1_1	261	265	PF00082	0.681
CLV_PCSK_SKI1_1	336	340	PF00082	0.818
CLV_PCSK_SKI1_1	357	361	PF00082	0.709
CLV_PCSK_SKI1_1	625	629	PF00082	0.777
CLV_PCSK_SKI1_1	63	67	PF00082	0.505
CLV_PCSK_SKI1_1	639	643	PF00082	0.661
CLV_PCSK_SKI1_1	711	715	PF00082	0.604
CLV_PCSK_SKI1_1	872	876	PF00082	0.757
CLV_Separin_Metazoa	170	174	PF03568	0.540
DEG_COP1_1	203	212	PF00400	0.692
DEG_Nend_UBRbox_1	1	4	PF02207	0.695
DEG_SPOP_SBC_1	431	435	PF00917	0.717
DEG_SPOP_SBC_1	566	570	PF00917	0.624
DEG_SPOP_SBC_1	608	612	PF00917	0.707
DEG_SPOP_SBC_1	645	649	PF00917	0.742
DOC_CDC14_PxL_1	56	64	PF14671	0.669
DOC_CKS1_1	228	233	PF01111	0.775
DOC_CKS1_1	343	348	PF01111	0.698
DOC_CKS1_1	478	483	PF01111	0.631
DOC_CKS1_1	915	920	PF01111	0.624
DOC_CYCLIN_RxL_1	354	363	PF00134	0.711
DOC_MAPK_FxFP_2	323	326	PF00069	0.779
DOC_MAPK_gen_1	948	956	PF00069	0.560
DOC_PP2B_LxvP_1	30	33	PF13499	0.732
DOC_PP2B_PxIxI_1	763	769	PF00149	0.725
DOC_PP4_FxxP_1	228	231	PF00568	0.772
DOC_PP4_FxxP_1	323	326	PF00568	0.779
DOC_PP4_FxxP_1	343	346	PF00568	0.518
DOC_PP4_FxxP_1	939	942	PF00568	0.713
DOC_USP7_MATH_1	122	126	PF00917	0.561
DOC_USP7_MATH_1	16	20	PF00917	0.757
DOC_USP7_MATH_1	202	206	PF00917	0.742
DOC_USP7_MATH_1	295	299	PF00917	0.764
DOC_USP7_MATH_1	326	330	PF00917	0.815
DOC_USP7_MATH_1	38	42	PF00917	0.714
DOC_USP7_MATH_1	431	435	PF00917	0.783
DOC_USP7_MATH_1	463	467	PF00917	0.712
DOC_USP7_MATH_1	557	561	PF00917	0.752
DOC_USP7_MATH_1	566	570	PF00917	0.697
DOC_USP7_MATH_1	588	592	PF00917	0.773
DOC_USP7_MATH_1	595	599	PF00917	0.783
DOC_USP7_MATH_1	603	607	PF00917	0.668
DOC_USP7_MATH_1	608	612	PF00917	0.596
DOC_USP7_MATH_1	632	636	PF00917	0.697
DOC_USP7_MATH_1	646	650	PF00917	0.560
DOC_USP7_MATH_1	724	728	PF00917	0.757
DOC_USP7_MATH_1	754	758	PF00917	0.761
DOC_USP7_MATH_1	774	778	PF00917	0.746
DOC_USP7_MATH_1	788	792	PF00917	0.586
DOC_USP7_MATH_1	858	862	PF00917	0.751
DOC_USP7_MATH_1	867	871	PF00917	0.684
DOC_USP7_MATH_1	883	887	PF00917	0.594
DOC_USP7_MATH_1	897	901	PF00917	0.690
DOC_USP7_MATH_1	909	913	PF00917	0.652
DOC_USP7_MATH_1	931	935	PF00917	0.599
DOC_USP7_UBL2_3	523	527	PF12436	0.737
DOC_WW_Pin1_4	10	15	PF00397	0.767
DOC_WW_Pin1_4	134	139	PF00397	0.707
DOC_WW_Pin1_4	208	213	PF00397	0.757
DOC_WW_Pin1_4	222	227	PF00397	0.620
DOC_WW_Pin1_4	246	251	PF00397	0.726
DOC_WW_Pin1_4	342	347	PF00397	0.698
DOC_WW_Pin1_4	407	412	PF00397	0.752
DOC_WW_Pin1_4	427	432	PF00397	0.763
DOC_WW_Pin1_4	477	482	PF00397	0.644
DOC_WW_Pin1_4	491	496	PF00397	0.646
DOC_WW_Pin1_4	584	589	PF00397	0.785
DOC_WW_Pin1_4	717	722	PF00397	0.670
DOC_WW_Pin1_4	772	777	PF00397	0.782
DOC_WW_Pin1_4	799	804	PF00397	0.707
DOC_WW_Pin1_4	814	819	PF00397	0.618
DOC_WW_Pin1_4	914	919	PF00397	0.628
LIG_14-3-3_CanoR_1	285	290	PF00244	0.670
LIG_14-3-3_CanoR_1	336	346	PF00244	0.813
LIG_14-3-3_CanoR_1	421	429	PF00244	0.743
LIG_14-3-3_CanoR_1	470	479	PF00244	0.647
LIG_14-3-3_CanoR_1	558	562	PF00244	0.716
LIG_14-3-3_CanoR_1	578	588	PF00244	0.793
LIG_14-3-3_CanoR_1	594	603	PF00244	0.601
LIG_14-3-3_CanoR_1	704	709	PF00244	0.719
LIG_14-3-3_CanoR_1	711	716	PF00244	0.652
LIG_14-3-3_CanoR_1	783	790	PF00244	0.774
LIG_14-3-3_CanoR_1	813	818	PF00244	0.800
LIG_14-3-3_CanoR_1	833	837	PF00244	0.533
LIG_14-3-3_CanoR_1	911	915	PF00244	0.651
LIG_BIR_III_4	873	877	PF00653	0.715
LIG_BRCT_BRCA1_1	127	131	PF00533	0.718
LIG_BRCT_BRCA1_1	224	228	PF00533	0.773
LIG_BRCT_BRCA1_1	339	343	PF00533	0.801
LIG_BRCT_BRCA1_1	801	805	PF00533	0.687
LIG_CSL_BTD_1	28	31	PF09270	0.739
LIG_CtBP_PxDLS_1	33	37	PF00389	0.550
LIG_deltaCOP1_diTrp_1	160	169	PF00928	0.648
LIG_EVH1_1	30	34	PF00568	0.730
LIG_FHA_1	284	290	PF00498	0.743
LIG_FHA_1	294	300	PF00498	0.604
LIG_FHA_1	566	572	PF00498	0.769
LIG_FHA_1	640	646	PF00498	0.762
LIG_FHA_1	68	74	PF00498	0.675
LIG_FHA_1	710	716	PF00498	0.782
LIG_FHA_1	733	739	PF00498	0.714
LIG_FHA_1	829	835	PF00498	0.745
LIG_FHA_1	847	853	PF00498	0.556
LIG_FHA_2	395	401	PF00498	0.743
LIG_FHA_2	570	576	PF00498	0.616
LIG_GBD_Chelix_1	360	368	PF00786	0.752
LIG_LIR_Apic_2	225	231	PF02991	0.768
LIG_LIR_Apic_2	340	346	PF02991	0.703
LIG_LIR_Apic_2	72	77	PF02991	0.673
LIG_LIR_Gen_1	128	138	PF02991	0.713
LIG_LIR_Gen_1	167	175	PF02991	0.605
LIG_LIR_LC3C_4	635	638	PF02991	0.599
LIG_LIR_Nem_3	128	134	PF02991	0.715
LIG_LIR_Nem_3	165	171	PF02991	0.610
LIG_LIR_Nem_3	455	459	PF02991	0.747
LIG_LRP6_Inhibitor_1	103	109	PF00058	0.615
LIG_MYND_1	485	489	PF01753	0.729
LIG_MYND_3	484	488	PF01753	0.737
LIG_PDZ_Class_2	951	956	PF00595	0.681
LIG_Pex14_1	164	168	PF04695	0.635
LIG_SH2_CRK	74	78	PF00017	0.673
LIG_SH2_SRC	252	255	PF00017	0.635
LIG_SH2_STAT3	352	355	PF00017	0.695
LIG_SH2_STAT5	133	136	PF00017	0.772
LIG_SH2_STAT5	252	255	PF00017	0.666
LIG_SH2_STAT5	61	64	PF00017	0.666
LIG_SH3_1	509	515	PF00018	0.687
LIG_SH3_1	676	682	PF00018	0.706
LIG_SH3_3	204	210	PF00018	0.754
LIG_SH3_3	25	31	PF00018	0.635
LIG_SH3_3	456	462	PF00018	0.603
LIG_SH3_3	492	498	PF00018	0.714
LIG_SH3_3	509	515	PF00018	0.544
LIG_SH3_3	558	564	PF00018	0.650
LIG_SH3_3	628	634	PF00018	0.608
LIG_SH3_3	676	682	PF00018	0.727
LIG_SH3_3	70	76	PF00018	0.675
LIG_SH3_3	718	724	PF00018	0.691
LIG_SH3_3	748	754	PF00018	0.741
LIG_SH3_3	757	763	PF00018	0.663
LIG_SH3_3	8	14	PF00018	0.713
LIG_SH3_3	833	839	PF00018	0.804
LIG_SH3_3	845	851	PF00018	0.643
LIG_SH3_3	891	897	PF00018	0.702
LIG_SH3_4	523	530	PF00018	0.730
LIG_SH3_4	880	887	PF00018	0.644
LIG_SUMO_SIM_par_1	549	554	PF11976	0.769
LIG_TRAF2_1	179	182	PF00917	0.607
LIG_WW_3	708	712	PF00397	0.642
LIG_WW_3	895	899	PF00397	0.608
MOD_CAAXbox	953	956	PF01239	0.737
MOD_CDK_SPK_2	208	213	PF00069	0.699
MOD_CDK_SPxxK_3	227	234	PF00069	0.775
MOD_CK1_1	125	131	PF00069	0.624
MOD_CK1_1	19	25	PF00069	0.716
MOD_CK1_1	203	209	PF00069	0.803
MOD_CK1_1	222	228	PF00069	0.523
MOD_CK1_1	288	294	PF00069	0.773
MOD_CK1_1	310	316	PF00069	0.847
MOD_CK1_1	329	335	PF00069	0.783
MOD_CK1_1	337	343	PF00069	0.692
MOD_CK1_1	353	359	PF00069	0.541
MOD_CK1_1	430	436	PF00069	0.781
MOD_CK1_1	455	461	PF00069	0.768
MOD_CK1_1	46	52	PF00069	0.610
MOD_CK1_1	5	11	PF00069	0.727
MOD_CK1_1	565	571	PF00069	0.799
MOD_CK1_1	587	593	PF00069	0.810
MOD_CK1_1	597	603	PF00069	0.657
MOD_CK1_1	611	617	PF00069	0.672
MOD_CK1_1	726	732	PF00069	0.791
MOD_CK1_1	775	781	PF00069	0.758
MOD_CK1_1	829	835	PF00069	0.797
MOD_CK1_1	83	89	PF00069	0.721
MOD_CK1_1	846	852	PF00069	0.567
MOD_CK1_1	887	893	PF00069	0.759
MOD_CK1_1	913	919	PF00069	0.776
MOD_CK1_1	940	946	PF00069	0.731
MOD_CK2_1	394	400	PF00069	0.789
MOD_CK2_1	501	507	PF00069	0.739
MOD_CK2_1	569	575	PF00069	0.616
MOD_CK2_1	61	67	PF00069	0.661
MOD_Cter_Amidation	665	668	PF01082	0.784
MOD_GlcNHglycan	18	21	PF01048	0.770
MOD_GlcNHglycan	293	296	PF01048	0.705
MOD_GlcNHglycan	336	339	PF01048	0.630
MOD_GlcNHglycan	36	39	PF01048	0.495
MOD_GlcNHglycan	370	373	PF01048	0.762
MOD_GlcNHglycan	382	385	PF01048	0.651
MOD_GlcNHglycan	386	389	PF01048	0.595
MOD_GlcNHglycan	40	43	PF01048	0.685
MOD_GlcNHglycan	45	48	PF01048	0.566
MOD_GlcNHglycan	471	474	PF01048	0.712
MOD_GlcNHglycan	488	492	PF01048	0.587
MOD_GlcNHglycan	503	506	PF01048	0.579
MOD_GlcNHglycan	553	556	PF01048	0.763
MOD_GlcNHglycan	564	567	PF01048	0.742
MOD_GlcNHglycan	597	600	PF01048	0.789
MOD_GlcNHglycan	603	606	PF01048	0.701
MOD_GlcNHglycan	613	616	PF01048	0.617
MOD_GlcNHglycan	683	686	PF01048	0.745
MOD_GlcNHglycan	688	691	PF01048	0.709
MOD_GlcNHglycan	696	699	PF01048	0.658
MOD_GlcNHglycan	740	743	PF01048	0.726
MOD_GlcNHglycan	845	848	PF01048	0.745
MOD_GlcNHglycan	919	922	PF01048	0.653
MOD_GlcNHglycan	933	936	PF01048	0.681
MOD_GSK3_1	215	222	PF00069	0.823
MOD_GSK3_1	230	237	PF00069	0.591
MOD_GSK3_1	291	298	PF00069	0.765
MOD_GSK3_1	309	316	PF00069	0.800
MOD_GSK3_1	325	332	PF00069	0.818
MOD_GSK3_1	34	41	PF00069	0.784
MOD_GSK3_1	374	381	PF00069	0.761
MOD_GSK3_1	394	401	PF00069	0.631
MOD_GSK3_1	407	414	PF00069	0.568
MOD_GSK3_1	427	434	PF00069	0.762
MOD_GSK3_1	438	445	PF00069	0.618
MOD_GSK3_1	487	494	PF00069	0.659
MOD_GSK3_1	5	12	PF00069	0.748
MOD_GSK3_1	562	569	PF00069	0.837
MOD_GSK3_1	580	587	PF00069	0.793
MOD_GSK3_1	593	600	PF00069	0.638
MOD_GSK3_1	603	610	PF00069	0.680
MOD_GSK3_1	641	648	PF00069	0.739
MOD_GSK3_1	709	716	PF00069	0.755
MOD_GSK3_1	723	730	PF00069	0.565
MOD_GSK3_1	764	771	PF00069	0.784
MOD_GSK3_1	772	779	PF00069	0.668
MOD_GSK3_1	789	796	PF00069	0.554
MOD_GSK3_1	824	831	PF00069	0.769
MOD_GSK3_1	839	846	PF00069	0.594
MOD_GSK3_1	858	865	PF00069	0.575
MOD_GSK3_1	883	890	PF00069	0.634
MOD_GSK3_1	909	916	PF00069	0.758
MOD_LATS_1	232	238	PF00433	0.776
MOD_N-GLC_1	203	208	PF02516	0.751
MOD_N-GLC_1	272	277	PF02516	0.628
MOD_N-GLC_1	863	868	PF02516	0.742
MOD_N-GLC_2	442	444	PF02516	0.731
MOD_NEK2_1	200	205	PF00069	0.712
MOD_NEK2_1	283	288	PF00069	0.762
MOD_NEK2_1	366	371	PF00069	0.756
MOD_NEK2_1	43	48	PF00069	0.561
MOD_NEK2_1	437	442	PF00069	0.743
MOD_NEK2_1	551	556	PF00069	0.819
MOD_NEK2_1	579	584	PF00069	0.747
MOD_NEK2_1	703	708	PF00069	0.734
MOD_NEK2_1	728	733	PF00069	0.780
MOD_NEK2_1	828	833	PF00069	0.635
MOD_NEK2_2	69	74	PF00069	0.678
MOD_PIKK_1	288	294	PF00454	0.733
MOD_PIKK_1	310	316	PF00454	0.734
MOD_PIKK_1	543	549	PF00454	0.614
MOD_PIKK_1	609	615	PF00454	0.721
MOD_PK_1	307	313	PF00069	0.795
MOD_PKA_1	307	313	PF00069	0.613
MOD_PKA_1	420	426	PF00069	0.740
MOD_PKA_2	307	313	PF00069	0.664
MOD_PKA_2	398	404	PF00069	0.745
MOD_PKA_2	420	426	PF00069	0.740
MOD_PKA_2	442	448	PF00069	0.821
MOD_PKA_2	469	475	PF00069	0.717
MOD_PKA_2	557	563	PF00069	0.839
MOD_PKA_2	579	585	PF00069	0.807
MOD_PKA_2	593	599	PF00069	0.624
MOD_PKA_2	601	607	PF00069	0.755
MOD_PKA_2	703	709	PF00069	0.722
MOD_PKA_2	782	788	PF00069	0.777
MOD_PKA_2	832	838	PF00069	0.744
MOD_PKA_2	897	903	PF00069	0.660
MOD_PKA_2	910	916	PF00069	0.675
MOD_PKB_1	305	313	PF00069	0.794
MOD_PKB_1	419	427	PF00069	0.742
MOD_PKB_1	578	586	PF00069	0.743
MOD_Plk_1	139	145	PF00069	0.732
MOD_Plk_1	203	209	PF00069	0.751
MOD_Plk_1	797	803	PF00069	0.655
MOD_Plk_1	824	830	PF00069	0.619
MOD_Plk_4	285	291	PF00069	0.730
MOD_Plk_4	295	301	PF00069	0.552
MOD_Plk_4	463	469	PF00069	0.753
MOD_Plk_4	632	638	PF00069	0.658
MOD_Plk_4	69	75	PF00069	0.622
MOD_Plk_4	733	739	PF00069	0.760
MOD_Plk_4	910	916	PF00069	0.628
MOD_ProDKin_1	10	16	PF00069	0.762
MOD_ProDKin_1	134	140	PF00069	0.707
MOD_ProDKin_1	208	214	PF00069	0.759
MOD_ProDKin_1	222	228	PF00069	0.622
MOD_ProDKin_1	246	252	PF00069	0.729
MOD_ProDKin_1	342	348	PF00069	0.697
MOD_ProDKin_1	407	413	PF00069	0.751
MOD_ProDKin_1	427	433	PF00069	0.760
MOD_ProDKin_1	477	483	PF00069	0.645
MOD_ProDKin_1	491	497	PF00069	0.640
MOD_ProDKin_1	584	590	PF00069	0.786
MOD_ProDKin_1	717	723	PF00069	0.660
MOD_ProDKin_1	772	778	PF00069	0.783
MOD_ProDKin_1	799	805	PF00069	0.707
MOD_ProDKin_1	814	820	PF00069	0.610
MOD_ProDKin_1	914	920	PF00069	0.629
MOD_SUMO_for_1	874	877	PF00179	0.778
MOD_SUMO_rev_2	182	191	PF00179	0.644
MOD_SUMO_rev_2	873	882	PF00179	0.647
TRG_DiLeu_BaEn_4	181	187	PF01217	0.614
TRG_DiLeu_BaLyEn_6	474	479	PF01217	0.642
TRG_DiLeu_BaLyEn_6	509	514	PF01217	0.693
TRG_ENDOCYTIC_2	133	136	PF00928	0.711
TRG_ENDOCYTIC_2	168	171	PF00928	0.541
TRG_ENDOCYTIC_2	97	100	PF00928	0.665
TRG_ER_diArg_1	153	155	PF00400	0.716
TRG_ER_diArg_1	172	174	PF00400	0.344
TRG_ER_diArg_1	267	269	PF00400	0.695
TRG_ER_diArg_1	300	303	PF00400	0.788
TRG_ER_diArg_1	305	308	PF00400	0.724
TRG_ER_diArg_1	419	422	PF00400	0.739
TRG_ER_diArg_1	448	450	PF00400	0.842
TRG_ER_diArg_1	661	663	PF00400	0.716
TRG_Pf-PMV_PEXEL_1	63	67	PF00026	0.505

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HKR8	Leishmania braziliensis	63%	99%
A4I898	Leishmania infantum	99%	100%
E9B356	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q4Z8	Leishmania major	88%	100%