LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7X5S5_LEIDO
TriTrypDb:
LdBPK_322400.1 , LdCL_320029300 , LDHU3_32.2980
Length:
347

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X5S5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5S5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 165 169 PF00656 0.662
CLV_C14_Caspase3-7 170 174 PF00656 0.642
CLV_C14_Caspase3-7 203 207 PF00656 0.685
CLV_NRD_NRD_1 243 245 PF00675 0.576
CLV_NRD_NRD_1 332 334 PF00675 0.556
CLV_PCSK_KEX2_1 242 244 PF00082 0.587
CLV_PCSK_KEX2_1 277 279 PF00082 0.536
CLV_PCSK_KEX2_1 319 321 PF00082 0.594
CLV_PCSK_PC1ET2_1 277 279 PF00082 0.569
CLV_PCSK_PC1ET2_1 319 321 PF00082 0.483
CLV_PCSK_PC7_1 238 244 PF00082 0.609
CLV_PCSK_SKI1_1 110 114 PF00082 0.475
CLV_PCSK_SKI1_1 319 323 PF00082 0.587
DEG_SPOP_SBC_1 194 198 PF00917 0.698
DOC_CYCLIN_RxL_1 313 324 PF00134 0.511
DOC_MAPK_gen_1 242 251 PF00069 0.564
DOC_MAPK_MEF2A_6 242 250 PF00069 0.468
DOC_WW_Pin1_4 171 176 PF00397 0.610
DOC_WW_Pin1_4 185 190 PF00397 0.554
DOC_WW_Pin1_4 293 298 PF00397 0.726
DOC_WW_Pin1_4 59 64 PF00397 0.674
LIG_14-3-3_CanoR_1 149 157 PF00244 0.551
LIG_14-3-3_CanoR_1 177 187 PF00244 0.687
LIG_14-3-3_CanoR_1 216 220 PF00244 0.741
LIG_14-3-3_CanoR_1 223 232 PF00244 0.655
LIG_AP2alpha_1 232 236 PF02296 0.470
LIG_BRCT_BRCA1_1 232 236 PF00533 0.690
LIG_FHA_1 10 16 PF00498 0.809
LIG_FHA_1 135 141 PF00498 0.507
LIG_FHA_1 179 185 PF00498 0.761
LIG_FHA_1 200 206 PF00498 0.699
LIG_FHA_1 261 267 PF00498 0.494
LIG_FHA_1 28 34 PF00498 0.563
LIG_FHA_1 326 332 PF00498 0.540
LIG_FHA_2 115 121 PF00498 0.484
LIG_FHA_2 196 202 PF00498 0.753
LIG_FHA_2 210 216 PF00498 0.716
LIG_LIR_Gen_1 229 236 PF02991 0.505
LIG_LIR_Nem_3 229 235 PF02991 0.523
LIG_LIR_Nem_3 341 347 PF02991 0.445
LIG_Pex14_2 232 236 PF04695 0.470
LIG_PTAP_UEV_1 288 293 PF05743 0.658
LIG_SH2_GRB2like 129 132 PF00017 0.524
LIG_SH2_STAP1 142 146 PF00017 0.540
LIG_SH2_STAT5 129 132 PF00017 0.505
LIG_SH2_STAT5 180 183 PF00017 0.704
LIG_SH3_1 299 305 PF00018 0.621
LIG_SH3_3 169 175 PF00018 0.698
LIG_SH3_3 214 220 PF00018 0.604
LIG_SH3_3 286 292 PF00018 0.736
LIG_SH3_3 299 305 PF00018 0.593
LIG_SUMO_SIM_anti_2 122 129 PF11976 0.564
LIG_TRAF2_1 279 282 PF00917 0.595
LIG_UBA3_1 248 254 PF00899 0.468
LIG_WW_3 305 309 PF00397 0.589
MOD_CDC14_SPxK_1 174 177 PF00782 0.602
MOD_CDK_SPxK_1 171 177 PF00069 0.602
MOD_CDK_SPxK_1 293 299 PF00069 0.593
MOD_CK1_1 10 16 PF00069 0.654
MOD_CK1_1 179 185 PF00069 0.696
MOD_CK1_1 196 202 PF00069 0.540
MOD_CK1_1 226 232 PF00069 0.678
MOD_CK1_1 3 9 PF00069 0.751
MOD_CK1_1 31 37 PF00069 0.753
MOD_CK1_1 40 46 PF00069 0.670
MOD_CK2_1 114 120 PF00069 0.595
MOD_CK2_1 26 32 PF00069 0.785
MOD_CK2_1 276 282 PF00069 0.590
MOD_GlcNHglycan 168 172 PF01048 0.770
MOD_GlcNHglycan 181 184 PF01048 0.560
MOD_GlcNHglycan 2 5 PF01048 0.689
MOD_GlcNHglycan 42 45 PF01048 0.753
MOD_GlcNHglycan 94 97 PF01048 0.606
MOD_GSK3_1 130 137 PF00069 0.358
MOD_GSK3_1 149 156 PF00069 0.453
MOD_GSK3_1 167 174 PF00069 0.685
MOD_GSK3_1 179 186 PF00069 0.768
MOD_GSK3_1 189 196 PF00069 0.712
MOD_GSK3_1 226 233 PF00069 0.701
MOD_GSK3_1 27 34 PF00069 0.697
MOD_GSK3_1 3 10 PF00069 0.725
MOD_GSK3_1 36 43 PF00069 0.730
MOD_GSK3_1 55 62 PF00069 0.438
MOD_GSK3_1 73 80 PF00069 0.694
MOD_N-GLC_1 130 135 PF02516 0.400
MOD_N-GLC_1 230 235 PF02516 0.613
MOD_N-GLC_1 40 45 PF02516 0.782
MOD_N-GLC_1 7 12 PF02516 0.784
MOD_NEK2_1 112 117 PF00069 0.510
MOD_NEK2_1 325 330 PF00069 0.450
MOD_NEK2_2 77 82 PF00069 0.627
MOD_PKA_2 148 154 PF00069 0.510
MOD_PKA_2 176 182 PF00069 0.758
MOD_PKA_2 215 221 PF00069 0.802
MOD_PKA_2 224 230 PF00069 0.456
MOD_PKB_1 223 231 PF00069 0.572
MOD_Plk_1 130 136 PF00069 0.402
MOD_Plk_1 167 173 PF00069 0.642
MOD_Plk_1 200 206 PF00069 0.702
MOD_Plk_1 209 215 PF00069 0.682
MOD_Plk_1 40 46 PF00069 0.803
MOD_Plk_2-3 209 215 PF00069 0.741
MOD_Plk_2-3 276 282 PF00069 0.583
MOD_Plk_4 130 136 PF00069 0.402
MOD_Plk_4 325 331 PF00069 0.504
MOD_ProDKin_1 171 177 PF00069 0.612
MOD_ProDKin_1 185 191 PF00069 0.556
MOD_ProDKin_1 293 299 PF00069 0.729
MOD_ProDKin_1 59 65 PF00069 0.673
TRG_DiLeu_BaLyEn_6 86 91 PF01217 0.566
TRG_ER_diArg_1 242 244 PF00400 0.587
TRG_Pf-PMV_PEXEL_1 278 282 PF00026 0.559

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I1Y8 Leptomonas seymouri 46% 99%
A4HKL6 Leishmania braziliensis 67% 98%
A4I848 Leishmania infantum 100% 100%
E9B306 Leishmania mexicana (strain MHOM/GT/2001/U1103) 89% 100%
Q4Q550 Leishmania major 93% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS