LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X5R6_LEIDO
TriTrypDb:
LdBPK_322620.1 , LdCL_320031900 , LDHU3_32.3280
Length:
134

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X5R6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5R6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 24 28 PF00656 0.663
CLV_C14_Caspase3-7 46 50 PF00656 0.594
CLV_PCSK_SKI1_1 107 111 PF00082 0.409
CLV_PCSK_SKI1_1 73 77 PF00082 0.541
CLV_PCSK_SKI1_1 86 90 PF00082 0.524
DOC_CYCLIN_yCln2_LP_2 109 115 PF00134 0.400
DOC_MAPK_MEF2A_6 123 132 PF00069 0.527
DOC_PP4_FxxP_1 64 67 PF00568 0.418
DOC_USP7_MATH_1 56 60 PF00917 0.552
DOC_WW_Pin1_4 4 9 PF00397 0.749
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I4I3 Leptomonas seymouri 61% 98%
A0A0S4IYR4 Bodo saltans 38% 92%
A0A1X0NRU4 Trypanosomatidae 39% 100%
A0A3R7MFQ9 Trypanosoma rangeli 47% 100%
A4HKN8 Leishmania braziliensis 74% 100%
A4I869 Leishmania infantum 100% 100%
D0AAD8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9B327 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
Q4Q527 Leishmania major 93% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS