DEAD/DEAH box helicase family protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X5R1_LEIDO

TriTrypDb:

LdBPK_322380.1 , LdCL_320029100 , LDHU3_32.2950

Length:

773

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X5R1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5R1

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000470	maturation of LSU-rRNA	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0034470	ncRNA processing	7	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.717
CLV_C14_Caspase3-7	426	430	PF00656	0.622
CLV_C14_Caspase3-7	435	439	PF00656	0.563
CLV_C14_Caspase3-7	473	477	PF00656	0.738
CLV_NRD_NRD_1	105	107	PF00675	0.570
CLV_NRD_NRD_1	109	111	PF00675	0.705
CLV_NRD_NRD_1	197	199	PF00675	0.484
CLV_NRD_NRD_1	333	335	PF00675	0.253
CLV_NRD_NRD_1	470	472	PF00675	0.711
CLV_NRD_NRD_1	520	522	PF00675	0.332
CLV_NRD_NRD_1	6	8	PF00675	0.548
CLV_NRD_NRD_1	727	729	PF00675	0.612
CLV_NRD_NRD_1	742	744	PF00675	0.421
CLV_NRD_NRD_1	88	90	PF00675	0.576
CLV_PCSK_FUR_1	106	110	PF00082	0.769
CLV_PCSK_KEX2_1	107	109	PF00082	0.505
CLV_PCSK_KEX2_1	196	198	PF00082	0.482
CLV_PCSK_KEX2_1	332	334	PF00082	0.261
CLV_PCSK_KEX2_1	520	522	PF00082	0.275
CLV_PCSK_KEX2_1	6	8	PF00082	0.549
CLV_PCSK_KEX2_1	727	729	PF00082	0.573
CLV_PCSK_KEX2_1	741	743	PF00082	0.458
CLV_PCSK_KEX2_1	88	90	PF00082	0.582
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.665
CLV_PCSK_PC1ET2_1	727	729	PF00082	0.580
CLV_PCSK_SKI1_1	143	147	PF00082	0.786
CLV_PCSK_SKI1_1	520	524	PF00082	0.298
DEG_APCC_DBOX_1	363	371	PF00400	0.532
DEG_APCC_DBOX_1	413	421	PF00400	0.526
DEG_APCC_DBOX_1	698	706	PF00400	0.318
DEG_APCC_DBOX_1	740	748	PF00400	0.638
DOC_ANK_TNKS_1	374	381	PF00023	0.450
DOC_CKS1_1	344	349	PF01111	0.450
DOC_CKS1_1	626	631	PF01111	0.387
DOC_CYCLIN_RxL_1	363	374	PF00134	0.442
DOC_CYCLIN_yClb1_LxF_4	621	627	PF00134	0.315
DOC_MAPK_gen_1	407	417	PF00069	0.521
DOC_MAPK_gen_1	520	527	PF00069	0.474
DOC_PP1_RVXF_1	254	261	PF00149	0.450
DOC_PP2B_LxvP_1	283	286	PF13499	0.491
DOC_PP2B_LxvP_1	587	590	PF13499	0.450
DOC_PP4_FxxP_1	139	142	PF00568	0.741
DOC_PP4_FxxP_1	206	209	PF00568	0.398
DOC_PP4_FxxP_1	260	263	PF00568	0.450
DOC_PP4_FxxP_1	52	55	PF00568	0.631
DOC_PP4_FxxP_1	626	629	PF00568	0.345
DOC_USP7_MATH_1	113	117	PF00917	0.764
DOC_USP7_MATH_1	403	407	PF00917	0.450
DOC_USP7_MATH_1	439	443	PF00917	0.713
DOC_USP7_MATH_1	444	448	PF00917	0.627
DOC_USP7_MATH_1	490	494	PF00917	0.489
DOC_USP7_MATH_1	590	594	PF00917	0.498
DOC_USP7_MATH_1	685	689	PF00917	0.377
DOC_USP7_MATH_1	710	714	PF00917	0.233
DOC_USP7_UBL2_3	4	8	PF12436	0.553
DOC_USP7_UBL2_3	729	733	PF12436	0.572
DOC_WW_Pin1_4	24	29	PF00397	0.589
DOC_WW_Pin1_4	343	348	PF00397	0.450
DOC_WW_Pin1_4	47	52	PF00397	0.595
DOC_WW_Pin1_4	625	630	PF00397	0.388
LIG_14-3-3_CanoR_1	174	183	PF00244	0.696
LIG_14-3-3_CanoR_1	396	400	PF00244	0.451
LIG_14-3-3_CanoR_1	414	418	PF00244	0.422
LIG_14-3-3_CanoR_1	509	515	PF00244	0.497
LIG_14-3-3_CanoR_1	562	567	PF00244	0.498
LIG_14-3-3_CanoR_1	610	620	PF00244	0.450
LIG_14-3-3_CanoR_1	735	740	PF00244	0.687
LIG_14-3-3_CanoR_1	88	98	PF00244	0.671
LIG_Actin_WH2_2	676	694	PF00022	0.423
LIG_APCC_ABBA_1	566	571	PF00400	0.491
LIG_BIR_III_2	476	480	PF00653	0.730
LIG_BIR_III_2	489	493	PF00653	0.549
LIG_BIR_III_4	57	61	PF00653	0.651
LIG_BRCT_BRCA1_1	532	536	PF00533	0.450
LIG_BRCT_BRCA1_1	542	546	PF00533	0.450
LIG_BRCT_BRCA1_1	622	626	PF00533	0.423
LIG_BRCT_BRCA1_1	66	70	PF00533	0.540
LIG_BRCT_BRCA1_1	705	709	PF00533	0.423
LIG_BRCT_BRCA1_1	767	771	PF00533	0.598
LIG_Clathr_ClatBox_1	210	214	PF01394	0.406
LIG_Clathr_ClatBox_1	367	371	PF01394	0.532
LIG_deltaCOP1_diTrp_1	571	578	PF00928	0.453
LIG_eIF4E_1	133	139	PF01652	0.728
LIG_FHA_1	124	130	PF00498	0.563
LIG_FHA_1	277	283	PF00498	0.468
LIG_FHA_1	285	291	PF00498	0.459
LIG_FHA_1	292	298	PF00498	0.395
LIG_FHA_1	563	569	PF00498	0.456
LIG_FHA_1	572	578	PF00498	0.426
LIG_FHA_1	603	609	PF00498	0.440
LIG_FHA_1	692	698	PF00498	0.318
LIG_FHA_2	424	430	PF00498	0.591
LIG_FHA_2	626	632	PF00498	0.385
LIG_FHA_2	721	727	PF00498	0.613
LIG_LIR_Apic_2	136	142	PF02991	0.683
LIG_LIR_Apic_2	257	263	PF02991	0.450
LIG_LIR_Apic_2	49	55	PF02991	0.669
LIG_LIR_Apic_2	623	629	PF02991	0.420
LIG_LIR_Apic_2	646	651	PF02991	0.389
LIG_LIR_Gen_1	242	250	PF02991	0.519
LIG_LIR_Gen_1	565	571	PF02991	0.503
LIG_LIR_Nem_3	242	247	PF02991	0.471
LIG_LIR_Nem_3	565	569	PF02991	0.492
LIG_LIR_Nem_3	631	637	PF02991	0.346
LIG_LIR_Nem_3	763	767	PF02991	0.559
LIG_LIR_Nem_3	92	97	PF02991	0.633
LIG_MLH1_MIPbox_1	66	70	PF16413	0.578
LIG_MYND_1	600	604	PF01753	0.450
LIG_PCNA_PIPBox_1	505	514	PF02747	0.411
LIG_PCNA_yPIPBox_3	375	389	PF02747	0.536
LIG_PCNA_yPIPBox_3	505	516	PF02747	0.411
LIG_PCNA_yPIPBox_3	653	665	PF02747	0.303
LIG_Pex14_1	594	598	PF04695	0.450
LIG_REV1ctd_RIR_1	67	75	PF16727	0.598
LIG_RPA_C_Fungi	193	205	PF08784	0.579
LIG_SH2_CRK	244	248	PF00017	0.296
LIG_SH2_CRK	512	516	PF00017	0.340
LIG_SH2_CRK	598	602	PF00017	0.290
LIG_SH2_NCK_1	454	458	PF00017	0.641
LIG_SH2_SRC	598	601	PF00017	0.290
LIG_SH2_STAT5	128	131	PF00017	0.728
LIG_SH2_STAT5	512	515	PF00017	0.320
LIG_SH2_STAT5	607	610	PF00017	0.292
LIG_SH2_STAT5	637	640	PF00017	0.404
LIG_SH2_STAT5	731	734	PF00017	0.562
LIG_SH3_1	598	604	PF00018	0.303
LIG_SH3_3	341	347	PF00018	0.303
LIG_SH3_3	598	604	PF00018	0.303
LIG_SH3_3	714	720	PF00018	0.318
LIG_SH3_3	764	770	PF00018	0.601
LIG_SUMO_SIM_anti_2	187	195	PF11976	0.653
LIG_SUMO_SIM_par_1	214	219	PF11976	0.491
LIG_SUMO_SIM_par_1	366	372	PF11976	0.418
LIG_TRAF2_1	628	631	PF00917	0.362
LIG_TRAF2_1	723	726	PF00917	0.561
LIG_UBA3_1	264	269	PF00899	0.370
LIG_WRC_WIRS_1	511	516	PF05994	0.423
LIG_WRC_WIRS_1	563	568	PF05994	0.377
MOD_CDC14_SPxK_1	50	53	PF00782	0.531
MOD_CDK_SPxK_1	343	349	PF00069	0.303
MOD_CDK_SPxK_1	47	53	PF00069	0.535
MOD_CK1_1	155	161	PF00069	0.710
MOD_CK1_1	254	260	PF00069	0.303
MOD_CK1_1	296	302	PF00069	0.372
MOD_CK1_1	39	45	PF00069	0.538
MOD_CK1_1	442	448	PF00069	0.617
MOD_CK1_1	481	487	PF00069	0.674
MOD_CK1_1	674	680	PF00069	0.318
MOD_CK2_1	175	181	PF00069	0.651
MOD_CK2_1	405	411	PF00069	0.318
MOD_CK2_1	429	435	PF00069	0.597
MOD_CK2_1	481	487	PF00069	0.732
MOD_CK2_1	625	631	PF00069	0.384
MOD_CK2_1	720	726	PF00069	0.559
MOD_Cter_Amidation	4	7	PF01082	0.557
MOD_Cter_Amidation	469	472	PF01082	0.674
MOD_GlcNHglycan	102	105	PF01048	0.721
MOD_GlcNHglycan	146	149	PF01048	0.697
MOD_GlcNHglycan	155	158	PF01048	0.677
MOD_GlcNHglycan	166	169	PF01048	0.720
MOD_GlcNHglycan	253	256	PF01048	0.303
MOD_GlcNHglycan	336	339	PF01048	0.360
MOD_GlcNHglycan	401	404	PF01048	0.303
MOD_GlcNHglycan	41	44	PF01048	0.682
MOD_GlcNHglycan	482	486	PF01048	0.679
MOD_GlcNHglycan	532	535	PF01048	0.423
MOD_GlcNHglycan	673	676	PF01048	0.305
MOD_GSK3_1	144	151	PF00069	0.728
MOD_GSK3_1	334	341	PF00069	0.419
MOD_GSK3_1	395	402	PF00069	0.303
MOD_GSK3_1	438	445	PF00069	0.677
MOD_GSK3_1	47	54	PF00069	0.531
MOD_GSK3_1	526	533	PF00069	0.303
MOD_GSK3_1	567	574	PF00069	0.377
MOD_GSK3_1	616	623	PF00069	0.512
MOD_N-GLC_1	752	757	PF02516	0.645
MOD_N-GLC_1	760	765	PF02516	0.594
MOD_NEK2_1	399	404	PF00069	0.304
MOD_NEK2_1	415	420	PF00069	0.407
MOD_NEK2_1	422	427	PF00069	0.392
MOD_NEK2_1	527	532	PF00069	0.303
MOD_NEK2_1	540	545	PF00069	0.269
MOD_NEK2_1	709	714	PF00069	0.357
MOD_PIKK_1	89	95	PF00454	0.667
MOD_PKA_1	89	95	PF00069	0.575
MOD_PKA_2	164	170	PF00069	0.710
MOD_PKA_2	227	233	PF00069	0.300
MOD_PKA_2	395	401	PF00069	0.297
MOD_PKA_2	413	419	PF00069	0.491
MOD_PKA_2	720	726	PF00069	0.643
MOD_PKB_1	332	340	PF00069	0.423
MOD_PKB_1	560	568	PF00069	0.411
MOD_Plk_1	113	119	PF00069	0.725
MOD_Plk_1	124	130	PF00069	0.616
MOD_Plk_1	233	239	PF00069	0.423
MOD_Plk_1	360	366	PF00069	0.370
MOD_Plk_2-3	429	435	PF00069	0.637
MOD_Plk_4	124	130	PF00069	0.689
MOD_Plk_4	293	299	PF00069	0.411
MOD_Plk_4	338	344	PF00069	0.328
MOD_Plk_4	395	401	PF00069	0.303
MOD_Plk_4	429	435	PF00069	0.542
MOD_Plk_4	510	516	PF00069	0.423
MOD_Plk_4	590	596	PF00069	0.388
MOD_Plk_4	620	626	PF00069	0.438
MOD_Plk_4	760	766	PF00069	0.536
MOD_ProDKin_1	24	30	PF00069	0.590
MOD_ProDKin_1	343	349	PF00069	0.303
MOD_ProDKin_1	47	53	PF00069	0.597
MOD_ProDKin_1	625	631	PF00069	0.384
MOD_SUMO_rev_2	456	464	PF00179	0.686
TRG_DiLeu_BaEn_1	189	194	PF01217	0.652
TRG_DiLeu_BaEn_1	242	247	PF01217	0.332
TRG_DiLeu_BaEn_1	331	336	PF01217	0.318
TRG_DiLeu_BaEn_2	629	635	PF01217	0.356
TRG_DiLeu_BaEn_2	759	765	PF01217	0.559
TRG_DiLeu_BaLyEn_6	206	211	PF01217	0.428
TRG_DiLeu_BaLyEn_6	260	265	PF01217	0.388
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.418
TRG_ENDOCYTIC_2	244	247	PF00928	0.303
TRG_ENDOCYTIC_2	512	515	PF00928	0.291
TRG_ER_diArg_1	10	13	PF00400	0.569
TRG_ER_diArg_1	106	109	PF00400	0.749
TRG_ER_diArg_1	196	198	PF00400	0.420
TRG_ER_diArg_1	332	334	PF00400	0.337
TRG_ER_diArg_1	364	367	PF00400	0.337
TRG_ER_diArg_1	560	563	PF00400	0.303
TRG_ER_diArg_1	741	743	PF00400	0.541
TRG_NES_CRM1_1	361	374	PF08389	0.314
TRG_NLS_Bipartite_1	88	110	PF00514	0.709
TRG_NLS_MonoCore_2	105	110	PF00514	0.744
TRG_NLS_MonoExtC_3	105	110	PF00514	0.719
TRG_NLS_MonoExtC_3	6	11	PF00514	0.559
TRG_NLS_MonoExtN_4	106	111	PF00514	0.738
TRG_NLS_MonoExtN_4	4	11	PF00514	0.563
TRG_Pf-PMV_PEXEL_1	366	371	PF00026	0.298
TRG_Pf-PMV_PEXEL_1	375	379	PF00026	0.311

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWK5	Leptomonas seymouri	74%	98%
A0A0N1I6K5	Leptomonas seymouri	33%	100%
A0A0N1PDE7	Leptomonas seymouri	25%	100%
A0A0S4IWD0	Bodo saltans	34%	100%
A0A0S4KKU4	Bodo saltans	64%	100%
A0A1X0NU42	Trypanosomatidae	28%	100%
A0A1X0NVK0	Trypanosomatidae	57%	100%
A0A3Q8ID91	Leishmania donovani	29%	100%
A0A3R7M1K3	Trypanosoma rangeli	56%	100%
A0A3R7NGQ1	Trypanosoma rangeli	35%	100%
A0A3R7RJV1	Trypanosoma rangeli	25%	100%
A0A3S5H5H4	Leishmania donovani	29%	100%
A0A3S5H6T7	Leishmania donovani	30%	100%
A0A3S7X579	Leishmania donovani	26%	100%
A0A3S7XAN8	Leishmania donovani	33%	100%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	30%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	30%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	28%	100%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	31%	100%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	33%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	100%
A4H481	Leishmania braziliensis	26%	100%
A4H7Y3	Leishmania braziliensis	29%	100%
A4HK38	Leishmania braziliensis	25%	100%
A4HKL3	Leishmania braziliensis	83%	99%
A4HN73	Leishmania braziliensis	31%	100%
A4HP48	Leishmania braziliensis	32%	100%
A4HSF8	Leishmania infantum	29%	100%
A4HWB0	Leishmania infantum	30%	100%
A4I3T6	Leishmania infantum	29%	100%
A4I7M5	Leishmania infantum	26%	100%
A4I846	Leishmania infantum	100%	100%
A4IDF5	Leishmania infantum	31%	100%
A4RGU2	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	32%	97%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	28%	100%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	27%	100%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	26%	100%
A5E2Z9	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	34%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	29%	88%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	32%	100%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	28%	100%
A7A237	Saccharomyces cerevisiae (strain YJM789)	26%	100%
A7ESL8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	31%	96%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	29%	88%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	31%	100%
A7TJS7	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	28%	100%
A7TNT1	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	28%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	22%	100%
D0A9S3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	25%	100%
D0AAB3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
E9AFM8	Leishmania major	32%	100%
E9AKE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AQ10	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B6T1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	100%
O80792	Arabidopsis thaliana	28%	91%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	32%	90%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	32%	90%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	35%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	35%	100%
P0CQ88	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	26%	100%
P0CQ89	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	26%	100%
P15424	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	32%	100%
P25808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	29%	100%
Q0CMM5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	96%
Q0CZS8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	32%	100%
Q0D622	Oryza sativa subsp. japonica	30%	100%
Q0DBS1	Oryza sativa subsp. japonica	31%	100%
Q0DBU5	Oryza sativa subsp. japonica	28%	100%
Q0DLB9	Oryza sativa subsp. japonica	32%	100%
Q0UHM7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	27%	93%
Q0UMB9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	31%	96%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	29%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	32%	100%
Q1E9T9	Coccidioides immitis (strain RS)	30%	100%
Q1EA54	Coccidioides immitis (strain RS)	32%	100%
Q1EB31	Coccidioides immitis (strain RS)	32%	96%
Q2NL08	Bos taurus	31%	100%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	29%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	29%	100%
Q4IEK8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	33%	100%
Q4P0Y5	Ustilago maydis (strain 521 / FGSC 9021)	26%	79%
Q4P9E5	Ustilago maydis (strain 521 / FGSC 9021)	30%	100%
Q4Q1P0	Leishmania major	31%	100%
Q4Q552	Leishmania major	95%	100%
Q4Q5M6	Leishmania major	26%	100%
Q4QFH1	Leishmania major	30%	100%
Q4QJG6	Leishmania major	28%	100%
Q4WM60	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	32%	98%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	29%	100%
Q54EC2	Dictyostelium discoideum	27%	100%
Q54Q94	Dictyostelium discoideum	31%	88%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	26%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	28%	100%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	31%	100%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	35%	100%
Q5B3H7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	100%
Q5BFU1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	95%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	29%	99%
Q5ZLN8	Gallus gallus	32%	100%
Q650T9	Oryza sativa subsp. japonica	29%	100%
Q6BH93	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	34%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	97%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	100%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	27%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	97%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	100%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	100%
Q6DRI7	Danio rerio	27%	100%
Q6FKS8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	27%	100%
Q6FNA2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	28%	80%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	100%
Q6K7R9	Oryza sativa subsp. japonica	28%	95%
Q6NZQ2	Mus musculus	31%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	29%	100%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	100%
Q7S2N9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	33%	100%
Q7XJN0	Arabidopsis thaliana	32%	100%
Q84T03	Oryza sativa subsp. japonica	35%	100%
Q86B47	Drosophila melanogaster	29%	79%
Q8JHJ2	Danio rerio	31%	100%
Q8NHQ9	Homo sapiens	31%	100%
Q8TFL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	100%
Q9C8S9	Arabidopsis thaliana	28%	97%
Q9H8H2	Homo sapiens	31%	91%
Q9UTP9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	33%	100%
Q9VHU1	Drosophila melanogaster	31%	100%
V5DCA1	Trypanosoma cruzi	57%	100%