LeishMANIAdb
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G-patch domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
G-patch domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X5P3_LEIDO
TriTrypDb:
LdBPK_322120.1 * , LdCL_320026600 , LDHU3_32.2630
Length:
126

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X5P3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5P3

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 122 124 PF00675 0.687
CLV_NRD_NRD_1 38 40 PF00675 0.564
CLV_NRD_NRD_1 85 87 PF00675 0.644
CLV_PCSK_KEX2_1 122 124 PF00082 0.687
CLV_PCSK_KEX2_1 14 16 PF00082 0.565
CLV_PCSK_KEX2_1 85 87 PF00082 0.644
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.550
DOC_ANK_TNKS_1 85 92 PF00023 0.648
DOC_WW_Pin1_4 121 126 PF00397 0.593
LIG_BIR_II_1 1 5 PF00653 0.602
LIG_LIR_Apic_2 114 119 PF02991 0.623
LIG_PDZ_Class_1 121 126 PF00595 0.549
LIG_PROFILIN_1 107 113 PF00235 0.584
LIG_SH2_CRK 116 120 PF00017 0.783
LIG_SH2_NCK_1 116 120 PF00017 0.625
LIG_SH3_1 105 111 PF00018 0.582
LIG_SH3_3 104 110 PF00018 0.583
LIG_SH3_3 6 12 PF00018 0.571
LIG_WW_2 110 113 PF00397 0.580
MOD_GlcNHglycan 32 35 PF01048 0.544
MOD_PIKK_1 43 49 PF00454 0.616
MOD_PIKK_1 50 56 PF00454 0.632
MOD_PIKK_1 57 63 PF00454 0.587
MOD_PIKK_1 64 70 PF00454 0.546
TRG_ER_diArg_1 17 20 PF00400 0.548
TRG_ER_diArg_1 84 86 PF00400 0.640

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I4P7 Leptomonas seymouri 56% 100%
A4HKI9 Leishmania braziliensis 63% 89%
A4I821 Leishmania infantum 86% 95%
E9B2X9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 69% 86%
Q4Q577 Leishmania major 74% 88%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS