Phosphoglycan_beta_1_-3_galactosyltransferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X5J8_LEIDO

TriTrypDb:

LdBPK_321600.1 , LdCL_320021600 , LDHU3_32.2020

Length:

516

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

Expansion

Sequence features

A0A3S7X5J8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5J8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	351	355	PF00656	0.431
CLV_C14_Caspase3-7	58	62	PF00656	0.424
CLV_NRD_NRD_1	10	12	PF00675	0.488
CLV_NRD_NRD_1	142	144	PF00675	0.650
CLV_NRD_NRD_1	370	372	PF00675	0.646
CLV_PCSK_FUR_1	368	372	PF00082	0.593
CLV_PCSK_FUR_1	8	12	PF00082	0.497
CLV_PCSK_KEX2_1	10	12	PF00082	0.488
CLV_PCSK_KEX2_1	210	212	PF00082	0.608
CLV_PCSK_KEX2_1	370	372	PF00082	0.647
CLV_PCSK_KEX2_1	419	421	PF00082	0.519
CLV_PCSK_KEX2_1	47	49	PF00082	0.781
CLV_PCSK_PC1ET2_1	210	212	PF00082	0.627
CLV_PCSK_PC1ET2_1	419	421	PF00082	0.519
CLV_PCSK_PC1ET2_1	47	49	PF00082	0.704
CLV_PCSK_SKI1_1	108	112	PF00082	0.617
CLV_PCSK_SKI1_1	217	221	PF00082	0.598
CLV_PCSK_SKI1_1	248	252	PF00082	0.685
CLV_PCSK_SKI1_1	333	337	PF00082	0.609
CLV_PCSK_SKI1_1	370	374	PF00082	0.629
CLV_PCSK_SKI1_1	48	52	PF00082	0.707
CLV_PCSK_SKI1_1	492	496	PF00082	0.706
CLV_PCSK_SKI1_1	75	79	PF00082	0.625
DEG_APCC_DBOX_1	72	80	PF00400	0.434
DEG_Nend_UBRbox_2	1	3	PF02207	0.648
DOC_CDC14_PxL_1	344	352	PF14671	0.400
DOC_CYCLIN_RxL_1	330	340	PF00134	0.354
DOC_CYCLIN_RxL_1	367	377	PF00134	0.430
DOC_MAPK_gen_1	143	149	PF00069	0.411
DOC_MAPK_gen_1	75	85	PF00069	0.467
DOC_PP2B_LxvP_1	285	288	PF13499	0.463
DOC_PP2B_LxvP_1	41	44	PF13499	0.540
DOC_PP2B_PxIxI_1	447	453	PF00149	0.444
DOC_USP7_MATH_1	235	239	PF00917	0.491
DOC_USP7_MATH_1	322	326	PF00917	0.363
DOC_USP7_MATH_1	415	419	PF00917	0.387
DOC_USP7_MATH_1	478	482	PF00917	0.537
DOC_WW_Pin1_4	388	393	PF00397	0.384
DOC_WW_Pin1_4	399	404	PF00397	0.322
DOC_WW_Pin1_4	470	475	PF00397	0.512
LIG_14-3-3_CanoR_1	248	257	PF00244	0.464
LIG_14-3-3_CanoR_1	289	293	PF00244	0.461
LIG_14-3-3_CanoR_1	306	310	PF00244	0.289
LIG_14-3-3_CanoR_1	320	330	PF00244	0.365
LIG_14-3-3_CanoR_1	509	516	PF00244	0.450
LIG_Actin_WH2_2	110	125	PF00022	0.380
LIG_Actin_WH2_2	304	322	PF00022	0.416
LIG_BRCT_BRCA1_1	324	328	PF00533	0.388
LIG_Clathr_ClatBox_1	428	432	PF01394	0.344
LIG_CSL_BTD_1	277	280	PF09270	0.449
LIG_deltaCOP1_diTrp_1	382	390	PF00928	0.364
LIG_FHA_1	122	128	PF00498	0.441
LIG_FHA_1	156	162	PF00498	0.408
LIG_FHA_1	165	171	PF00498	0.365
LIG_FHA_1	447	453	PF00498	0.504
LIG_FHA_2	218	224	PF00498	0.356
LIG_FHA_2	267	273	PF00498	0.461
LIG_FHA_2	322	328	PF00498	0.428
LIG_LIR_Apic_2	275	281	PF02991	0.428
LIG_LIR_Gen_1	16	26	PF02991	0.512
LIG_LIR_Gen_1	168	179	PF02991	0.445
LIG_LIR_Gen_1	294	305	PF02991	0.494
LIG_LIR_Gen_1	308	317	PF02991	0.292
LIG_LIR_Gen_1	343	350	PF02991	0.416
LIG_LIR_Gen_1	508	516	PF02991	0.492
LIG_LIR_Nem_3	16	21	PF02991	0.615
LIG_LIR_Nem_3	168	174	PF02991	0.431
LIG_LIR_Nem_3	294	300	PF02991	0.465
LIG_LIR_Nem_3	308	312	PF02991	0.310
LIG_LIR_Nem_3	343	347	PF02991	0.406
LIG_LIR_Nem_3	382	388	PF02991	0.375
LIG_LIR_Nem_3	508	513	PF02991	0.491
LIG_MYND_1	86	90	PF01753	0.461
LIG_NRBOX	331	337	PF00104	0.409
LIG_NRBOX	368	374	PF00104	0.378
LIG_PCNA_yPIPBox_3	333	345	PF02747	0.399
LIG_Pex14_1	103	107	PF04695	0.401
LIG_Pex14_1	384	388	PF04695	0.371
LIG_Pex14_2	422	426	PF04695	0.305
LIG_SH2_CRK	107	111	PF00017	0.410
LIG_SH2_CRK	18	22	PF00017	0.492
LIG_SH2_CRK	297	301	PF00017	0.461
LIG_SH2_CRK	309	313	PF00017	0.342
LIG_SH2_NCK_1	297	301	PF00017	0.396
LIG_SH2_STAP1	18	22	PF00017	0.512
LIG_SH2_STAP1	214	218	PF00017	0.411
LIG_SH2_STAP1	297	301	PF00017	0.456
LIG_SH2_STAP1	381	385	PF00017	0.368
LIG_SH2_STAT5	156	159	PF00017	0.409
LIG_SH2_STAT5	169	172	PF00017	0.327
LIG_SH2_STAT5	284	287	PF00017	0.446
LIG_SH2_STAT5	87	90	PF00017	0.461
LIG_SH3_1	193	199	PF00018	0.463
LIG_SH3_3	193	199	PF00018	0.496
LIG_SH3_3	274	280	PF00018	0.484
LIG_Sin3_3	19	26	PF02671	0.468
LIG_SUMO_SIM_par_1	145	152	PF11976	0.433
LIG_SUMO_SIM_par_1	448	454	PF11976	0.486
LIG_TRAF2_1	301	304	PF00917	0.443
LIG_TRAF2_1	500	503	PF00917	0.417
LIG_TYR_ITIM	105	110	PF00017	0.402
LIG_TYR_ITIM	307	312	PF00017	0.391
LIG_UBA3_1	413	419	PF00899	0.378
LIG_WRC_WIRS_1	341	346	PF05994	0.378
MOD_CK1_1	136	142	PF00069	0.476
MOD_CK1_1	291	297	PF00069	0.456
MOD_CK1_1	469	475	PF00069	0.473
MOD_CK1_1	477	483	PF00069	0.433
MOD_CK2_1	217	223	PF00069	0.358
MOD_CK2_1	266	272	PF00069	0.461
MOD_CK2_1	321	327	PF00069	0.438
MOD_CK2_1	502	508	PF00069	0.482
MOD_GlcNHglycan	124	127	PF01048	0.607
MOD_GlcNHglycan	135	138	PF01048	0.706
MOD_GlcNHglycan	175	178	PF01048	0.657
MOD_GlcNHglycan	324	327	PF01048	0.624
MOD_GlcNHglycan	455	458	PF01048	0.701
MOD_GlcNHglycan	467	471	PF01048	0.662
MOD_GSK3_1	122	129	PF00069	0.489
MOD_GSK3_1	165	172	PF00069	0.431
MOD_GSK3_1	242	249	PF00069	0.541
MOD_GSK3_1	259	266	PF00069	0.438
MOD_GSK3_1	288	295	PF00069	0.454
MOD_GSK3_1	466	473	PF00069	0.507
MOD_GSK3_1	474	481	PF00069	0.459
MOD_GSK3_1	63	70	PF00069	0.501
MOD_N-GLC_1	127	132	PF02516	0.677
MOD_N-GLC_1	292	297	PF02516	0.693
MOD_NEK2_1	106	111	PF00069	0.405
MOD_NEK2_1	122	127	PF00069	0.369
MOD_NEK2_1	292	297	PF00069	0.493
MOD_NEK2_1	305	310	PF00069	0.324
MOD_NEK2_1	6	11	PF00069	0.641
MOD_NEK2_1	63	68	PF00069	0.483
MOD_PIKK_1	235	241	PF00454	0.516
MOD_PIKK_1	264	270	PF00454	0.487
MOD_PIKK_1	272	278	PF00454	0.473
MOD_PKA_2	288	294	PF00069	0.451
MOD_PKA_2	305	311	PF00069	0.284
MOD_PKA_2	322	328	PF00069	0.337
MOD_PKA_2	508	514	PF00069	0.447
MOD_Plk_1	292	298	PF00069	0.535
MOD_Plk_4	129	135	PF00069	0.464
MOD_Plk_4	165	171	PF00069	0.431
MOD_Plk_4	292	298	PF00069	0.462
MOD_Plk_4	340	346	PF00069	0.423
MOD_ProDKin_1	388	394	PF00069	0.385
MOD_ProDKin_1	399	405	PF00069	0.318
MOD_ProDKin_1	470	476	PF00069	0.511
MOD_SUMO_for_1	13	16	PF00179	0.669
TRG_DiLeu_BaLyEn_6	368	373	PF01217	0.425
TRG_ENDOCYTIC_2	107	110	PF00928	0.407
TRG_ENDOCYTIC_2	18	21	PF00928	0.607
TRG_ENDOCYTIC_2	284	287	PF00928	0.446
TRG_ENDOCYTIC_2	297	300	PF00928	0.434
TRG_ENDOCYTIC_2	309	312	PF00928	0.295
TRG_ER_diArg_1	368	371	PF00400	0.452
TRG_ER_diArg_1	7	10	PF00400	0.706
TRG_ER_diArg_1	73	76	PF00400	0.434
TRG_ER_diArg_1	79	82	PF00400	0.415
TRG_Pf-PMV_PEXEL_1	108	113	PF00026	0.616
TRG_Pf-PMV_PEXEL_1	333	338	PF00026	0.611
TRG_Pf-PMV_PEXEL_1	370	375	PF00026	0.624

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HKE0	Leishmania braziliensis	53%	100%
A4I7W8	Leishmania infantum	99%	100%
E9B2S8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q5C9	Leishmania major	82%	100%