G5-interacting protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

G5-interacting protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X5G1_LEIDO

TriTrypDb:

LdBPK_321430.1 , LdCL_320020000 , LDHU3_32.1800

Length:

790

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X5G1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X5G1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	673	677	PF00656	0.579
CLV_C14_Caspase3-7	775	779	PF00656	0.532
CLV_NRD_NRD_1	748	750	PF00675	0.434
CLV_PCSK_KEX2_1	274	276	PF00082	0.564
CLV_PCSK_KEX2_1	467	469	PF00082	0.594
CLV_PCSK_KEX2_1	662	664	PF00082	0.462
CLV_PCSK_KEX2_1	748	750	PF00082	0.434
CLV_PCSK_PC1ET2_1	274	276	PF00082	0.559
CLV_PCSK_PC1ET2_1	467	469	PF00082	0.594
CLV_PCSK_PC1ET2_1	662	664	PF00082	0.462
CLV_PCSK_PC7_1	463	469	PF00082	0.585
CLV_PCSK_SKI1_1	321	325	PF00082	0.524
CLV_PCSK_SKI1_1	543	547	PF00082	0.545
CLV_PCSK_SKI1_1	730	734	PF00082	0.677
DEG_SIAH_1	237	245	PF03145	0.555
DOC_CKS1_1	499	504	PF01111	0.376
DOC_CYCLIN_yClb5_NLxxxL_5	522	531	PF00134	0.500
DOC_MAPK_FxFP_2	655	658	PF00069	0.459
DOC_MAPK_gen_1	429	437	PF00069	0.493
DOC_MAPK_gen_1	662	669	PF00069	0.412
DOC_MAPK_gen_1	738	746	PF00069	0.571
DOC_MAPK_HePTP_8	416	428	PF00069	0.324
DOC_MAPK_MEF2A_6	419	428	PF00069	0.547
DOC_MAPK_MEF2A_6	662	669	PF00069	0.412
DOC_PIKK_1	408	416	PF02985	0.499
DOC_PP1_RVXF_1	374	381	PF00149	0.569
DOC_PP2B_LxvP_1	235	238	PF13499	0.781
DOC_PP4_FxxP_1	639	642	PF00568	0.407
DOC_PP4_FxxP_1	655	658	PF00568	0.406
DOC_PP4_FxxP_1	765	768	PF00568	0.528
DOC_PP4_MxPP_1	225	228	PF00568	0.587
DOC_USP7_MATH_1	190	194	PF00917	0.758
DOC_USP7_MATH_1	208	212	PF00917	0.691
DOC_USP7_MATH_1	422	426	PF00917	0.502
DOC_USP7_MATH_1	461	465	PF00917	0.472
DOC_USP7_MATH_1	549	553	PF00917	0.539
DOC_USP7_MATH_1	607	611	PF00917	0.557
DOC_USP7_UBL2_3	261	265	PF12436	0.550
DOC_USP7_UBL2_3	327	331	PF12436	0.599
DOC_USP7_UBL2_3	382	386	PF12436	0.586
DOC_USP7_UBL2_3	730	734	PF12436	0.644
DOC_USP7_UBL2_3	736	740	PF12436	0.620
DOC_WW_Pin1_4	248	253	PF00397	0.563
DOC_WW_Pin1_4	282	287	PF00397	0.494
DOC_WW_Pin1_4	309	314	PF00397	0.521
DOC_WW_Pin1_4	498	503	PF00397	0.378
DOC_WW_Pin1_4	752	757	PF00397	0.532
LIG_14-3-3_CanoR_1	233	238	PF00244	0.787
LIG_14-3-3_CanoR_1	376	381	PF00244	0.566
LIG_BIR_II_1	1	5	PF00653	0.724
LIG_BRCT_BRCA1_1	599	603	PF00533	0.538
LIG_BRCT_BRCA1_2	599	605	PF00533	0.552
LIG_Clathr_ClatBox_1	562	566	PF01394	0.499
LIG_deltaCOP1_diTrp_1	676	681	PF00928	0.451
LIG_eIF4E_1	348	354	PF01652	0.489
LIG_FHA_1	369	375	PF00498	0.380
LIG_FHA_1	499	505	PF00498	0.431
LIG_FHA_1	662	668	PF00498	0.449
LIG_FHA_1	713	719	PF00498	0.492
LIG_FHA_2	448	454	PF00498	0.486
LIG_FHA_2	473	479	PF00498	0.556
LIG_LIR_Apic_2	438	444	PF02991	0.554
LIG_LIR_Apic_2	473	479	PF02991	0.443
LIG_LIR_Gen_1	109	118	PF02991	0.816
LIG_LIR_Gen_1	276	286	PF02991	0.533
LIG_LIR_Gen_1	484	493	PF02991	0.431
LIG_LIR_Gen_1	516	527	PF02991	0.430
LIG_LIR_Nem_3	109	114	PF02991	0.785
LIG_LIR_Nem_3	276	281	PF02991	0.485
LIG_LIR_Nem_3	484	488	PF02991	0.408
LIG_LIR_Nem_3	516	522	PF02991	0.405
LIG_LIR_Nem_3	523	528	PF02991	0.374
LIG_LIR_Nem_3	600	606	PF02991	0.510
LIG_LIR_Nem_3	628	633	PF02991	0.525
LIG_LIR_Nem_3	646	650	PF02991	0.477
LIG_LIR_Nem_3	680	684	PF02991	0.386
LIG_PTB_Apo_2	40	47	PF02174	0.760
LIG_PTB_Apo_2	51	58	PF02174	0.757
LIG_PTB_Apo_2	651	658	PF02174	0.501
LIG_PTB_Phospho_1	40	46	PF10480	0.764
LIG_PTB_Phospho_1	51	57	PF10480	0.755
LIG_PTB_Phospho_1	651	657	PF10480	0.522
LIG_Rb_LxCxE_1	559	578	PF01857	0.512
LIG_SH2_CRK	111	115	PF00017	0.786
LIG_SH2_CRK	141	145	PF00017	0.787
LIG_SH2_CRK	525	529	PF00017	0.383
LIG_SH2_CRK	630	634	PF00017	0.531
LIG_SH2_GRB2like	111	114	PF00017	0.786
LIG_SH2_GRB2like	52	55	PF00017	0.741
LIG_SH2_NCK_1	476	480	PF00017	0.480
LIG_SH2_PTP2	280	283	PF00017	0.420
LIG_SH2_PTP2	519	522	PF00017	0.391
LIG_SH2_SRC	52	55	PF00017	0.774
LIG_SH2_STAP1	472	476	PF00017	0.574
LIG_SH2_STAP1	514	518	PF00017	0.481
LIG_SH2_STAP1	688	692	PF00017	0.570
LIG_SH2_STAT3	153	156	PF00017	0.728
LIG_SH2_STAT5	134	137	PF00017	0.776
LIG_SH2_STAT5	246	249	PF00017	0.724
LIG_SH2_STAT5	280	283	PF00017	0.420
LIG_SH2_STAT5	348	351	PF00017	0.390
LIG_SH2_STAT5	352	355	PF00017	0.411
LIG_SH2_STAT5	441	444	PF00017	0.540
LIG_SH2_STAT5	472	475	PF00017	0.544
LIG_SH2_STAT5	481	484	PF00017	0.407
LIG_SH2_STAT5	485	488	PF00017	0.321
LIG_SH2_STAT5	498	501	PF00017	0.336
LIG_SH2_STAT5	519	522	PF00017	0.353
LIG_SH2_STAT5	575	578	PF00017	0.397
LIG_SH2_STAT5	684	687	PF00017	0.439
LIG_SH3_1	441	447	PF00018	0.532
LIG_SH3_3	101	107	PF00018	0.733
LIG_SH3_3	160	166	PF00018	0.774
LIG_SH3_3	224	230	PF00018	0.736
LIG_SH3_3	3	9	PF00018	0.752
LIG_SH3_3	441	447	PF00018	0.430
LIG_SH3_3	463	469	PF00018	0.507
LIG_SH3_3	89	95	PF00018	0.718
LIG_SUMO_SIM_anti_2	402	410	PF11976	0.488
LIG_SUMO_SIM_anti_2	423	428	PF11976	0.479
LIG_SUMO_SIM_anti_2	507	513	PF11976	0.354
LIG_SUMO_SIM_par_1	704	710	PF11976	0.522
LIG_TRAF2_1	306	309	PF00917	0.616
LIG_TRAF2_1	537	540	PF00917	0.490
LIG_UBA3_1	541	546	PF00899	0.512
LIG_UBA3_1	579	584	PF00899	0.425
LIG_ULM_U2AF65_1	748	753	PF00076	0.501
LIG_WRC_WIRS_1	678	683	PF05994	0.498
LIG_WRC_WIRS_1	743	748	PF05994	0.544
MOD_CDK_SPK_2	248	253	PF00069	0.611
MOD_CDK_SPxxK_3	309	316	PF00069	0.586
MOD_CK1_1	245	251	PF00069	0.636
MOD_CK1_1	608	614	PF00069	0.517
MOD_CK1_1	696	702	PF00069	0.566
MOD_CK1_1	772	778	PF00069	0.542
MOD_CK2_1	309	315	PF00069	0.548
MOD_CK2_1	369	375	PF00069	0.574
MOD_CK2_1	447	453	PF00069	0.518
MOD_CK2_1	472	478	PF00069	0.519
MOD_CK2_1	544	550	PF00069	0.586
MOD_GlcNHglycan	120	123	PF01048	0.704
MOD_GlcNHglycan	217	220	PF01048	0.796
MOD_GlcNHglycan	289	292	PF01048	0.627
MOD_GlcNHglycan	327	330	PF01048	0.528
MOD_GlcNHglycan	33	36	PF01048	0.740
MOD_GlcNHglycan	462	466	PF01048	0.455
MOD_GlcNHglycan	490	493	PF01048	0.533
MOD_GlcNHglycan	550	554	PF01048	0.624
MOD_GlcNHglycan	92	95	PF01048	0.789
MOD_GSK3_1	229	236	PF00069	0.708
MOD_GSK3_1	260	267	PF00069	0.541
MOD_GSK3_1	376	383	PF00069	0.618
MOD_GSK3_1	470	477	PF00069	0.471
MOD_GSK3_1	692	699	PF00069	0.526
MOD_GSK3_1	7	14	PF00069	0.791
MOD_GSK3_1	730	737	PF00069	0.696
MOD_GSK3_1	778	785	PF00069	0.556
MOD_N-GLC_1	178	183	PF02516	0.511
MOD_N-GLC_1	18	23	PF02516	0.816
MOD_N-GLC_1	608	613	PF02516	0.514
MOD_N-GLC_2	133	135	PF02516	0.776
MOD_NEK2_1	178	183	PF00069	0.755
MOD_NEK2_1	287	292	PF00069	0.545
MOD_NEK2_1	380	385	PF00069	0.587
MOD_NEK2_1	488	493	PF00069	0.476
MOD_NEK2_1	599	604	PF00069	0.494
MOD_NEK2_1	693	698	PF00069	0.516
MOD_NEK2_1	728	733	PF00069	0.666
MOD_NEK2_2	514	519	PF00069	0.476
MOD_PIKK_1	106	112	PF00454	0.820
MOD_PIKK_1	556	562	PF00454	0.564
MOD_PIKK_1	755	761	PF00454	0.508
MOD_PK_1	233	239	PF00069	0.785
MOD_PKA_2	696	702	PF00069	0.570
MOD_Plk_1	178	184	PF00069	0.487
MOD_Plk_1	368	374	PF00069	0.476
MOD_Plk_1	422	428	PF00069	0.463
MOD_Plk_1	461	467	PF00069	0.521
MOD_Plk_1	514	520	PF00069	0.471
MOD_Plk_1	565	571	PF00069	0.384
MOD_Plk_1	608	614	PF00069	0.515
MOD_Plk_2-3	369	375	PF00069	0.574
MOD_Plk_4	178	184	PF00069	0.487
MOD_Plk_4	242	248	PF00069	0.742
MOD_Plk_4	369	375	PF00069	0.542
MOD_Plk_4	422	428	PF00069	0.390
MOD_Plk_4	507	513	PF00069	0.396
MOD_Plk_4	514	520	PF00069	0.415
MOD_Plk_4	565	571	PF00069	0.416
MOD_Plk_4	772	778	PF00069	0.519
MOD_ProDKin_1	248	254	PF00069	0.548
MOD_ProDKin_1	282	288	PF00069	0.494
MOD_ProDKin_1	309	315	PF00069	0.522
MOD_ProDKin_1	498	504	PF00069	0.377
MOD_ProDKin_1	752	758	PF00069	0.534
MOD_SUMO_for_1	273	276	PF00179	0.570
MOD_SUMO_for_1	411	414	PF00179	0.598
MOD_SUMO_for_1	435	438	PF00179	0.491
MOD_SUMO_for_1	545	548	PF00179	0.544
MOD_SUMO_rev_2	408	413	PF00179	0.608
MOD_SUMO_rev_2	616	625	PF00179	0.502
MOD_SUMO_rev_2	659	664	PF00179	0.576
TRG_DiLeu_BaEn_1	369	374	PF01217	0.566
TRG_DiLeu_BaEn_1	423	428	PF01217	0.462
TRG_DiLeu_BaEn_2	437	443	PF01217	0.547
TRG_DiLeu_BaLyEn_6	610	615	PF01217	0.500
TRG_ENDOCYTIC_2	111	114	PF00928	0.819
TRG_ENDOCYTIC_2	134	137	PF00928	0.776
TRG_ENDOCYTIC_2	141	144	PF00928	0.666
TRG_ENDOCYTIC_2	280	283	PF00928	0.513
TRG_ENDOCYTIC_2	485	488	PF00928	0.407
TRG_ENDOCYTIC_2	519	522	PF00928	0.342
TRG_ENDOCYTIC_2	525	528	PF00928	0.342
TRG_ENDOCYTIC_2	630	633	PF00928	0.512
TRG_ER_diArg_1	665	668	PF00400	0.487
TRG_NLS_MonoExtC_3	542	548	PF00514	0.542

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P989	Leptomonas seymouri	58%	99%
A0A0S4IM67	Bodo saltans	23%	100%
A0A1X0NUG5	Trypanosomatidae	35%	100%
A0A422NI97	Trypanosoma rangeli	35%	100%
A4HKC5	Leishmania braziliensis	84%	98%
A4I7V2	Leishmania infantum	99%	100%
D0AA13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9B2R2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q4Q5E5	Leishmania major	94%	99%