Ribosomal protein L22p/L17e, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L17, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X567_LEIDO

TriTrypDb:

LdBPK_240040.1 , LdCL_320009300 , LDHU3_32.0540

Length:

166

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 24

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 16
NetGPI	no	yes: 0, no: 16

Cellular components
Term	Name	Level	Count
GO:0015934	large ribosomal subunit	4	17
GO:0032991	protein-containing complex	1	17
GO:0044391	ribosomal subunit	3	17
GO:1990904	ribonucleoprotein complex	2	17
GO:0005730	nucleolus	5	1
GO:0005737	cytoplasm	2	2
GO:0022625	cytosolic large ribosomal subunit	5	2
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3S7X567

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X567

PDB structure(s): 6az3_T

Function

Biological processes
Term	Name	Level	Count
GO:0006412	translation	4	17
GO:0006518	peptide metabolic process	4	17
GO:0006807	nitrogen compound metabolic process	2	17
GO:0008152	metabolic process	1	17
GO:0009058	biosynthetic process	2	17
GO:0009059	macromolecule biosynthetic process	4	17
GO:0009987	cellular process	1	17
GO:0019538	protein metabolic process	3	17
GO:0034641	cellular nitrogen compound metabolic process	3	17
GO:0034645	obsolete cellular macromolecule biosynthetic process	4	17
GO:0043043	peptide biosynthetic process	5	17
GO:0043170	macromolecule metabolic process	3	17
GO:0043603	amide metabolic process	3	17
GO:0043604	amide biosynthetic process	4	17
GO:0044237	cellular metabolic process	2	17
GO:0044238	primary metabolic process	2	17
GO:0044249	cellular biosynthetic process	3	17
GO:0044260	obsolete cellular macromolecule metabolic process	3	17
GO:0044271	cellular nitrogen compound biosynthetic process	4	17
GO:0071704	organic substance metabolic process	2	17
GO:1901564	organonitrogen compound metabolic process	3	17
GO:1901566	organonitrogen compound biosynthetic process	4	17
GO:1901576	organic substance biosynthetic process	3	17
GO:0002181	cytoplasmic translation	5	2

Molecular functions
Term	Name	Level	Count
GO:0003735	structural constituent of ribosome	2	17
GO:0005198	structural molecule activity	1	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	127	129	PF00675	0.292
CLV_NRD_NRD_1	41	43	PF00675	0.264
CLV_NRD_NRD_1	5	7	PF00675	0.444
CLV_NRD_NRD_1	84	86	PF00675	0.271
CLV_PCSK_FUR_1	124	128	PF00082	0.264
CLV_PCSK_KEX2_1	126	128	PF00082	0.294
CLV_PCSK_KEX2_1	61	63	PF00082	0.264
CLV_PCSK_PC1ET2_1	61	63	PF00082	0.264
CLV_PCSK_SKI1_1	13	17	PF00082	0.383
CLV_PCSK_SKI1_1	49	53	PF00082	0.266
DOC_USP7_MATH_1	17	21	PF00917	0.277
DOC_USP7_MATH_1	8	12	PF00917	0.445
DOC_USP7_MATH_1	84	88	PF00917	0.264
DOC_USP7_MATH_1	90	94	PF00917	0.264
DOC_USP7_UBL2_3	161	165	PF12436	0.542
DOC_WW_Pin1_4	134	139	PF00397	0.269
LIG_14-3-3_CanoR_1	126	131	PF00244	0.294
LIG_14-3-3_CanoR_1	85	89	PF00244	0.264
LIG_deltaCOP1_diTrp_1	75	83	PF00928	0.264
LIG_FHA_1	30	36	PF00498	0.264
LIG_FHA_1	53	59	PF00498	0.264
LIG_SH2_CRK	48	52	PF00017	0.264
LIG_SH3_3	154	160	PF00018	0.494
LIG_UBA3_1	91	96	PF00899	0.264
MOD_CK1_1	11	17	PF00069	0.437
MOD_GlcNHglycan	13	16	PF01048	0.415
MOD_GlcNHglycan	161	164	PF01048	0.598
MOD_NEK2_1	52	57	PF00069	0.287
MOD_PKA_1	126	132	PF00069	0.294
MOD_PKA_2	126	132	PF00069	0.292
MOD_PKA_2	84	90	PF00069	0.264
MOD_PKB_1	124	132	PF00069	0.264
MOD_Plk_4	84	90	PF00069	0.270
MOD_ProDKin_1	134	140	PF00069	0.269
TRG_ENDOCYTIC_2	48	51	PF00928	0.264
TRG_ER_diArg_1	124	127	PF00400	0.264

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P862	Leptomonas seymouri	96%	100%
A0A0N1HTK5	Leptomonas seymouri	95%	100%
A0A0S4IWY7	Bodo saltans	88%	100%
A0A0S4IYA7	Bodo saltans	89%	93%
A0A1X0NJJ8	Trypanosomatidae	92%	100%
A0A3R7KF74	Trypanosoma rangeli	92%	100%
A0A3S7WY02	Leishmania donovani	99%	100%
A0A422P439	Trypanosoma rangeli	93%	100%
A0B9W5	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	29%	100%
A0NGY0	Anopheles gambiae	56%	89%
A0RVX8	Cenarchaeum symbiosum (strain A)	30%	100%
A1RVA1	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	32%	90%
A1RXG7	Thermofilum pendens (strain DSM 2475 / Hrk 5)	33%	100%
A2BMC4	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	33%	100%
A2I3Y6	Maconellicoccus hirsutus	53%	90%
A2SPK8	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	30%	100%
A3CT02	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	31%	100%
A3DNB2	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	37%	100%
A3MTL6	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	34%	90%
A4FWB7	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	29%	100%
A4HD62	Leishmania braziliensis	98%	100%
A4I0M7	Leishmania infantum	99%	100%
A4I7K7	Leishmania infantum	99%	100%
A4WIY9	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	33%	90%
A4YCX1	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	27%	100%
A5UL84	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	32%	100%
A6UQ48	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	34%	100%
A6UWU2	Methanococcus aeolicus (strain ATCC BAA-1280 / DSM 17508 / OCM 812 / Nankai-3)	33%	100%
A6VGY9	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	29%	100%
A7I5P4	Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8)	25%	100%
A8AA19	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	34%	100%
A8CAG3	Phlebotomus papatasi	55%	89%
A8MBL4	Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167)	28%	90%
A9A5J0	Nitrosopumilus maritimus (strain SCM1)	30%	100%
A9A9R0	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	29%	100%
B1YD24	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	30%	90%
D0A0B2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	88%	100%
E9AWJ4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
O14339	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	53%	89%
O26115	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	35%	100%
O28359	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	33%	100%
O48557	Zea mays	54%	97%
O59423	Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)	33%	100%
O59794	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	53%	89%
P05740	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	90%
P0DJ16	Tetrahymena thermophila (strain SB210)	52%	91%
P10970	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	30%	100%
P15008	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	30%	100%
P18621	Homo sapiens	54%	90%
P24049	Rattus norvegicus	55%	90%
P35266	Hordeum vulgare	54%	98%
P35267	Hordeum vulgare	54%	97%
P37380	Podocoryna carnea	55%	91%
P46990	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	52%	90%
P51413	Arabidopsis thaliana	54%	95%
P54033	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	32%	100%
P62649	Methanococcus maripaludis (strain S2 / LL)	29%	100%
P62650	Nanoarchaeum equitans (strain Kin4-M)	29%	95%
Q09JW2	Argas monolakensis	57%	90%
Q0PXV9	Diaphorina citri	54%	90%
Q0W1Y4	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	30%	100%
Q12ZU6	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	34%	100%
Q18GF4	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	29%	100%
Q1HR65	Aedes aegypti	54%	89%
Q29IM3	Drosophila pseudoobscura pseudoobscura	55%	89%
Q2FT36	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	31%	100%
Q2NFW1	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	35%	100%
Q3IMY3	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	29%	100%
Q3T025	Bos taurus	55%	90%
Q46GA0	Methanosarcina barkeri (strain Fusaro / DSM 804)	31%	100%
Q4GXH5	Carabus granulatus	52%	91%
Q4GXH6	Biphyllus lunatus	52%	92%
Q4GXH7	Agriotes lineatus	54%	88%
Q4JB45	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	30%	100%
Q4KTG9	Suberites domuncula	52%	87%
Q4N4B9	Theileria parva	47%	89%
Q4PM54	Ixodes scapularis	56%	90%
Q4Q5P2	Leishmania major	99%	100%
Q4QAX6	Leishmania major	99%	100%
Q4UF75	Theileria annulata	48%	89%
Q54NG2	Dictyostelium discoideum	53%	92%
Q59TE0	Candida albicans (strain SC5314 / ATCC MYA-2876)	52%	90%
Q5I5J1	Pectinaria gouldii	53%	91%
Q5JDH4	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	35%	100%
Q5MGD1	Lonomia obliqua	55%	89%
Q5MIR6	Aedes albopictus	54%	89%
Q5UAS2	Bombyx mori	53%	89%
Q5XTY7	Felis catus	54%	90%
Q6BM53	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	50%	90%
Q6CBS7	Yarrowia lipolytica (strain CLIB 122 / E 150)	49%	90%
Q6L1C2	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	27%	100%
Q6MY48	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	52%	86%
Q6XJ13	Drosophila yakuba	55%	89%
Q8PV45	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	30%	100%
Q8TRU2	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	29%	100%
Q8TX36	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	33%	100%
Q8U003	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	34%	100%
Q8ZWH7	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	31%	90%
Q93VI3	Arabidopsis thaliana	53%	94%
Q975I6	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	30%	100%
Q97BX2	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	27%	100%
Q9BL19	Caenorhabditis elegans	54%	89%
Q9CPR4	Mus musculus	55%	90%
Q9HE25	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	50%	89%
Q9HIR4	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	29%	100%
Q9UXA2	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	30%	100%
Q9V1U0	Pyrococcus abyssi (strain GE5 / Orsay)	34%	100%
Q9W3W8	Drosophila melanogaster	55%	89%
Q9YF76	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	36%	100%