G protein gamma domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X508_LEIDO

TriTrypDb:

LdBPK_312870.1 , LdCL_310037100 , LDHU3_31.5020

Length:

237

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X508

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X508

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	192	196	PF00656	0.553
CLV_C14_Caspase3-7	215	219	PF00656	0.573
CLV_NRD_NRD_1	47	49	PF00675	0.659
CLV_NRD_NRD_1	90	92	PF00675	0.752
CLV_NRD_NRD_1	97	99	PF00675	0.670
CLV_PCSK_FUR_1	44	48	PF00082	0.663
CLV_PCSK_FUR_1	88	92	PF00082	0.651
CLV_PCSK_KEX2_1	46	48	PF00082	0.732
CLV_PCSK_KEX2_1	88	90	PF00082	0.769
DEG_Nend_Nbox_1	1	3	PF02207	0.665
DOC_USP7_MATH_1	123	127	PF00917	0.794
DOC_USP7_MATH_1	174	178	PF00917	0.600
DOC_USP7_MATH_1	97	101	PF00917	0.611
DOC_USP7_UBL2_3	224	228	PF12436	0.614
DOC_WW_Pin1_4	112	117	PF00397	0.652
DOC_WW_Pin1_4	131	136	PF00397	0.675
DOC_WW_Pin1_4	165	170	PF00397	0.675
LIG_14-3-3_CanoR_1	179	187	PF00244	0.560
LIG_14-3-3_CanoR_1	88	94	PF00244	0.631
LIG_14-3-3_CanoR_1	98	106	PF00244	0.602
LIG_BIR_III_2	218	222	PF00653	0.592
LIG_FHA_2	102	108	PF00498	0.685
LIG_FHA_2	125	131	PF00498	0.794
LIG_FHA_2	190	196	PF00498	0.578
LIG_FHA_2	36	42	PF00498	0.553
LIG_RPA_C_Fungi	86	98	PF08784	0.545
LIG_SH3_3	139	145	PF00018	0.645
LIG_SH3_3	161	167	PF00018	0.574
LIG_SH3_3	34	40	PF00018	0.661
LIG_SH3_3	78	84	PF00018	0.651
LIG_TRAF2_1	154	157	PF00917	0.670
LIG_TRAF2_1	170	173	PF00917	0.547
LIG_TRAF2_1	203	206	PF00917	0.611
MOD_CAAXbox	234	237	PF01239	0.644
MOD_CDC14_SPxK_1	134	137	PF00782	0.628
MOD_CDK_SPK_2	112	117	PF00069	0.592
MOD_CDK_SPxK_1	131	137	PF00069	0.629
MOD_CK1_1	49	55	PF00069	0.659
MOD_CK2_1	101	107	PF00069	0.663
MOD_CK2_1	123	129	PF00069	0.793
MOD_CK2_1	182	188	PF00069	0.649
MOD_CK2_1	35	41	PF00069	0.550
MOD_CK2_1	63	69	PF00069	0.782
MOD_GlcNHglycan	175	179	PF01048	0.637
MOD_GlcNHglycan	195	198	PF01048	0.683
MOD_GSK3_1	12	19	PF00069	0.627
MOD_GSK3_1	174	181	PF00069	0.592
MOD_GSK3_1	182	189	PF00069	0.554
MOD_GSK3_1	46	53	PF00069	0.695
MOD_GSK3_1	97	104	PF00069	0.587
MOD_N-GLC_1	112	117	PF02516	0.644
MOD_N-GLC_1	56	61	PF02516	0.687
MOD_NEK2_1	2	7	PF00069	0.611
MOD_PIKK_1	101	107	PF00454	0.585
MOD_PIKK_1	12	18	PF00454	0.552
MOD_PIKK_1	50	56	PF00454	0.696
MOD_PKA_1	46	52	PF00069	0.601
MOD_PKA_1	89	95	PF00069	0.658
MOD_PKA_2	178	184	PF00069	0.618
MOD_PKA_2	46	52	PF00069	0.661
MOD_PKA_2	89	95	PF00069	0.634
MOD_PKA_2	97	103	PF00069	0.612
MOD_PKB_1	44	52	PF00069	0.644
MOD_PKB_1	89	97	PF00069	0.660
MOD_ProDKin_1	112	118	PF00069	0.655
MOD_ProDKin_1	131	137	PF00069	0.677
MOD_ProDKin_1	165	171	PF00069	0.677
TRG_ER_diArg_1	46	48	PF00400	0.607
TRG_ER_diArg_1	87	90	PF00400	0.636
TRG_Pf-PMV_PEXEL_1	91	96	PF00026	0.663

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HJR6	Leishmania braziliensis	38%	100%
A4I783	Leishmania infantum	100%	100%
E9B277	Leishmania mexicana (strain MHOM/GT/2001/U1103)	70%	100%
Q4Q5Y2	Leishmania major	79%	100%