2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7X4X4_LEIDO

TriTrypDb:

LdBPK_312710.1 , LdCL_310035100 , LDHU3_31.4790

Length:

626

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 24

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 31
NetGPI	no	yes: 0, no: 31

Cellular components
Term	Name	Level	Count
GO:0005739	mitochondrion	5	3
GO:0032991	protein-containing complex	1	3
GO:0043226	organelle	2	3
GO:0043227	membrane-bounded organelle	3	3
GO:0043229	intracellular organelle	3	3
GO:0043231	intracellular membrane-bounded organelle	4	3
GO:0045239	tricarboxylic acid cycle enzyme complex	3	3
GO:0045240	dihydrolipoyl dehydrogenase complex	4	3
GO:0045252	oxoglutarate dehydrogenase complex	4	3
GO:0110165	cellular anatomical entity	1	3
GO:1902494	catalytic complex	2	3
GO:1990204	oxidoreductase complex	3	3
GO:1990234	transferase complex	3	3

Expansion

Sequence features

A0A3S7X4X4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4X4

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	32
GO:0019725	cellular homeostasis	2	32
GO:0042592	homeostatic process	3	32
GO:0045454	cell redox homeostasis	3	32
GO:0050789	regulation of biological process	2	32
GO:0050794	regulation of cellular process	3	32
GO:0065007	biological regulation	1	32
GO:0065008	regulation of biological quality	2	32

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	32
GO:0003824	catalytic activity	1	32
GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity	5	6
GO:0005488	binding	1	32
GO:0016491	oxidoreductase activity	2	32
GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	4	6
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	3	6
GO:0036094	small molecule binding	2	32
GO:0043167	ion binding	2	32
GO:0043168	anion binding	3	32
GO:0050660	flavin adenine dinucleotide binding	4	32
GO:0097159	organic cyclic compound binding	2	32
GO:1901265	nucleoside phosphate binding	3	32
GO:1901363	heterocyclic compound binding	2	32
GO:0004148	dihydrolipoyl dehydrogenase activity	5	12
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3	12
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4	12
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3	3
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4	3
GO:0019152	acetoin dehydrogenase activity	5	3
GO:0052587	diacetyl reductase ((R)-acetoin forming) activity	6	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	208	212	PF00656	0.465
CLV_NRD_NRD_1	362	364	PF00675	0.335
CLV_NRD_NRD_1	62	64	PF00675	0.429
CLV_PCSK_FUR_1	546	550	PF00082	0.347
CLV_PCSK_KEX2_1	362	364	PF00082	0.367
CLV_PCSK_KEX2_1	548	550	PF00082	0.359
CLV_PCSK_KEX2_1	62	64	PF00082	0.429
CLV_PCSK_PC1ET2_1	548	550	PF00082	0.309
CLV_PCSK_PC7_1	358	364	PF00082	0.212
CLV_PCSK_SKI1_1	108	112	PF00082	0.536
CLV_PCSK_SKI1_1	234	238	PF00082	0.307
CLV_PCSK_SKI1_1	388	392	PF00082	0.440
CLV_PCSK_SKI1_1	523	527	PF00082	0.362
CLV_PCSK_SKI1_1	548	552	PF00082	0.295
DEG_APCC_DBOX_1	131	139	PF00400	0.377
DEG_APCC_DBOX_1	383	391	PF00400	0.396
DEG_Nend_Nbox_1	1	3	PF02207	0.417
DEG_ODPH_VHL_1	43	54	PF01847	0.385
DOC_ANK_TNKS_1	508	515	PF00023	0.200
DOC_CYCLIN_RxL_1	105	114	PF00134	0.596
DOC_CYCLIN_yCln2_LP_2	305	311	PF00134	0.165
DOC_CYCLIN_yCln2_LP_2	43	49	PF00134	0.392
DOC_MAPK_gen_1	329	337	PF00069	0.335
DOC_MAPK_gen_1	546	553	PF00069	0.285
DOC_PP2B_LxvP_1	305	308	PF13499	0.208
DOC_PP2B_LxvP_1	43	46	PF13499	0.388
DOC_PP4_FxxP_1	251	254	PF00568	0.262
DOC_PP4_FxxP_1	303	306	PF00568	0.224
DOC_USP7_MATH_1	586	590	PF00917	0.320
DOC_USP7_MATH_1	606	610	PF00917	0.500
DOC_USP7_MATH_1	68	72	PF00917	0.435
DOC_USP7_MATH_1	81	85	PF00917	0.391
DOC_USP7_MATH_2	203	209	PF00917	0.189
DOC_WW_Pin1_4	35	40	PF00397	0.393
DOC_WW_Pin1_4	472	477	PF00397	0.499
DOC_WW_Pin1_4	53	58	PF00397	0.384
DOC_WW_Pin1_4	618	623	PF00397	0.350
DOC_WW_Pin1_4	98	103	PF00397	0.698
LIG_14-3-3_CanoR_1	112	116	PF00244	0.546
LIG_14-3-3_CanoR_1	19	25	PF00244	0.404
LIG_14-3-3_CanoR_1	295	305	PF00244	0.303
LIG_14-3-3_CanoR_1	384	388	PF00244	0.380
LIG_14-3-3_CanoR_1	453	458	PF00244	0.350
LIG_14-3-3_CanoR_1	67	76	PF00244	0.425
LIG_14-3-3_CanoR_1	88	96	PF00244	0.399
LIG_APCC_ABBA_1	257	262	PF00400	0.224
LIG_BIR_III_4	449	453	PF00653	0.330
LIG_BRCT_BRCA1_1	284	288	PF00533	0.224
LIG_BRCT_BRCA1_1	90	94	PF00533	0.688
LIG_BRCT_BRCA1_1	96	100	PF00533	0.400
LIG_BRCT_BRCA1_2	284	290	PF00533	0.224
LIG_Clathr_ClatBox_1	373	377	PF01394	0.291
LIG_CtBP_PxDLS_1	25	29	PF00389	0.384
LIG_eIF4E_1	355	361	PF01652	0.367
LIG_FHA_1	217	223	PF00498	0.438
LIG_FHA_1	277	283	PF00498	0.278
LIG_FHA_1	524	530	PF00498	0.379
LIG_FHA_2	190	196	PF00498	0.319
LIG_FHA_2	223	229	PF00498	0.318
LIG_FHA_2	619	625	PF00498	0.399
LIG_LIR_Apic_2	250	254	PF02991	0.349
LIG_LIR_Apic_2	300	306	PF02991	0.224
LIG_LIR_Gen_1	325	335	PF02991	0.286
LIG_LIR_Gen_1	535	542	PF02991	0.255
LIG_LIR_Gen_1	575	586	PF02991	0.295
LIG_LIR_Nem_3	17	21	PF02991	0.431
LIG_LIR_Nem_3	230	236	PF02991	0.353
LIG_LIR_Nem_3	264	270	PF02991	0.293
LIG_LIR_Nem_3	29	35	PF02991	0.385
LIG_LIR_Nem_3	325	330	PF02991	0.286
LIG_LIR_Nem_3	521	525	PF02991	0.339
LIG_LIR_Nem_3	575	581	PF02991	0.260
LIG_LIR_Nem_3	71	76	PF02991	0.396
LIG_LIR_Nem_3	97	103	PF02991	0.650
LIG_LYPXL_yS_3	587	590	PF13949	0.291
LIG_PCNA_yPIPBox_3	465	477	PF02747	0.298
LIG_PCNA_yPIPBox_3	573	581	PF02747	0.413
LIG_PDZ_Class_3	621	626	PF00595	0.587
LIG_PTB_Apo_2	581	588	PF02174	0.396
LIG_PTB_Phospho_1	581	587	PF10480	0.396
LIG_SH2_CRK	267	271	PF00017	0.250
LIG_SH2_CRK	578	582	PF00017	0.335
LIG_SH2_NCK_1	78	82	PF00017	0.397
LIG_SH2_SRC	182	185	PF00017	0.200
LIG_SH2_STAT5	355	358	PF00017	0.385
LIG_SH2_STAT5	445	448	PF00017	0.385
LIG_SH2_STAT5	515	518	PF00017	0.323
LIG_SH2_STAT5	578	581	PF00017	0.405
LIG_SH2_STAT5	76	79	PF00017	0.407
LIG_SH3_1	582	588	PF00018	0.367
LIG_SH3_3	116	122	PF00018	0.623
LIG_SH3_3	582	588	PF00018	0.367
LIG_SH3_3	93	99	PF00018	0.648
LIG_SUMO_SIM_par_1	23	29	PF11976	0.385
LIG_SUMO_SIM_par_1	45	51	PF11976	0.382
LIG_SUMO_SIM_par_1	562	568	PF11976	0.269
LIG_TRAF2_1	378	381	PF00917	0.350
LIG_TYR_ITIM	520	525	PF00017	0.224
LIG_UBA3_1	326	334	PF00899	0.411
LIG_WW_3	85	89	PF00397	0.393
MOD_CDC14_SPxK_1	60	63	PF00782	0.404
MOD_CDK_SPK_2	472	477	PF00069	0.533
MOD_CDK_SPK_2	57	62	PF00069	0.404
MOD_CDK_SPxK_1	57	63	PF00069	0.398
MOD_CDK_SPxxK_3	618	625	PF00069	0.521
MOD_CK1_1	20	26	PF00069	0.413
MOD_CK1_1	38	44	PF00069	0.390
MOD_CK1_1	576	582	PF00069	0.312
MOD_CK1_1	589	595	PF00069	0.290
MOD_CK2_1	189	195	PF00069	0.332
MOD_CK2_1	222	228	PF00069	0.295
MOD_CK2_1	559	565	PF00069	0.275
MOD_GlcNHglycan	125	128	PF01048	0.629
MOD_GlcNHglycan	22	25	PF01048	0.392
MOD_GlcNHglycan	238	242	PF01048	0.343
MOD_GlcNHglycan	391	394	PF01048	0.383
MOD_GlcNHglycan	591	594	PF01048	0.442
MOD_GlcNHglycan	70	73	PF01048	0.482
MOD_GlcNHglycan	90	93	PF01048	0.552
MOD_GSK3_1	212	219	PF00069	0.364
MOD_GSK3_1	483	490	PF00069	0.473
MOD_GSK3_1	497	504	PF00069	0.339
MOD_GSK3_1	53	60	PF00069	0.423
MOD_GSK3_1	94	101	PF00069	0.400
MOD_N-GLC_1	297	302	PF02516	0.224
MOD_N-GLC_1	573	578	PF02516	0.313
MOD_N-GLC_1	618	623	PF02516	0.410
MOD_NEK2_1	110	115	PF00069	0.577
MOD_NEK2_1	187	192	PF00069	0.407
MOD_NEK2_1	222	227	PF00069	0.265
MOD_NEK2_1	237	242	PF00069	0.319
MOD_NEK2_1	26	31	PF00069	0.385
MOD_NEK2_1	330	335	PF00069	0.306
MOD_NEK2_1	418	423	PF00069	0.286
MOD_NEK2_1	478	483	PF00069	0.548
MOD_NEK2_1	48	53	PF00069	0.389
MOD_NEK2_1	525	530	PF00069	0.273
MOD_NEK2_2	383	388	PF00069	0.291
MOD_PIKK_1	216	222	PF00454	0.406
MOD_PIKK_1	38	44	PF00454	0.400
MOD_PK_1	573	579	PF00069	0.347
MOD_PKA_2	111	117	PF00069	0.563
MOD_PKA_2	216	222	PF00069	0.348
MOD_PKA_2	383	389	PF00069	0.314
MOD_PKA_2	606	612	PF00069	0.490
MOD_Plk_1	26	32	PF00069	0.398
MOD_Plk_1	573	579	PF00069	0.392
MOD_Plk_2-3	205	211	PF00069	0.396
MOD_Plk_4	205	211	PF00069	0.365
MOD_Plk_4	307	313	PF00069	0.291
MOD_Plk_4	322	328	PF00069	0.285
MOD_Plk_4	351	357	PF00069	0.403
MOD_Plk_4	467	473	PF00069	0.440
MOD_Plk_4	559	565	PF00069	0.303
MOD_Plk_4	573	579	PF00069	0.291
MOD_Plk_4	586	592	PF00069	0.307
MOD_ProDKin_1	35	41	PF00069	0.395
MOD_ProDKin_1	472	478	PF00069	0.500
MOD_ProDKin_1	53	59	PF00069	0.387
MOD_ProDKin_1	618	624	PF00069	0.361
MOD_ProDKin_1	98	104	PF00069	0.698
MOD_SUMO_for_1	572	575	PF00179	0.200
MOD_SUMO_rev_2	240	250	PF00179	0.449
TRG_DiLeu_BaEn_2	231	237	PF01217	0.200
TRG_DiLeu_BaLyEn_6	43	48	PF01217	0.390
TRG_ENDOCYTIC_2	233	236	PF00928	0.360
TRG_ENDOCYTIC_2	267	270	PF00928	0.282
TRG_ENDOCYTIC_2	441	444	PF00928	0.316
TRG_ENDOCYTIC_2	522	525	PF00928	0.318
TRG_ENDOCYTIC_2	578	581	PF00928	0.286
TRG_ENDOCYTIC_2	587	590	PF00928	0.284
TRG_ER_diArg_1	361	363	PF00400	0.411
TRG_ER_diArg_1	61	63	PF00400	0.409
TRG_Pf-PMV_PEXEL_1	268	273	PF00026	0.367
TRG_Pf-PMV_PEXEL_1	343	348	PF00026	0.291

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P491	Leptomonas seymouri	25%	100%
A0A0N1HUA4	Leptomonas seymouri	36%	100%
A0A0N1I1H2	Leptomonas seymouri	24%	100%
A0A0N1IHT7	Leptomonas seymouri	37%	100%
A0A0N1IIN8	Leptomonas seymouri	69%	100%
A0A0S4J6A3	Bodo saltans	25%	100%
A0A0S4JDA8	Bodo saltans	26%	100%
A0A0S4KLJ6	Bodo saltans	35%	99%
A0A1X0NJ18	Trypanosomatidae	39%	98%
A0A1X0NK15	Trypanosomatidae	47%	100%
A0A1X0NRW2	Trypanosomatidae	26%	100%
A0A1X0NZX1	Trypanosomatidae	38%	100%
A0A1X0P0G9	Trypanosomatidae	25%	100%
A0A3Q8IDT8	Leishmania donovani	38%	100%
A0A3Q8IF30	Leishmania donovani	35%	100%
A0A3Q8ITM5	Leishmania donovani	25%	100%
A0A3R7KY91	Trypanosoma rangeli	26%	100%
A0A3R7NB58	Trypanosoma rangeli	24%	100%
A0A3R7NSH5	Trypanosoma rangeli	39%	100%
A0A3S7WP12	Leishmania donovani	23%	100%
A0A422NPA5	Trypanosoma rangeli	36%	100%
A0A422NPB5	Trypanosoma rangeli	46%	100%
A1AIE2	Escherichia coli O1:K1 / APEC	26%	100%
A1JI37	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	28%	100%
A1KM51	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	28%	100%
A1U1Y5	Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)	27%	100%
A2TIL1	Callithrix jacchus	27%	100%
A4H480	Leishmania braziliensis	23%	100%
A4HIY7	Leishmania braziliensis	39%	100%
A4HJQ2	Leishmania braziliensis	85%	100%
A4HJQ3	Leishmania braziliensis	35%	100%
A4HKX6	Leishmania braziliensis	24%	97%
A4HSF7	Leishmania infantum	23%	100%
A4I4P1	Leishmania infantum	38%	100%
A4I769	Leishmania infantum	100%	100%
A4I8F6	Leishmania infantum	25%	100%
A4TRG4	Yersinia pestis (strain Pestoides F)	27%	100%
A4VMU6	Pseudomonas stutzeri (strain A1501)	27%	100%
A4WG49	Enterobacter sp. (strain 638)	26%	100%
A4XSQ1	Pseudomonas mendocina (strain ymp)	26%	100%
A5F4K5	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	28%	100%
A5U665	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	28%	100%
A5W6F5	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	26%	100%
A6TGE6	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	27%	100%
A6V3A6	Pseudomonas aeruginosa (strain PA7)	27%	100%
A6VW16	Marinomonas sp. (strain MWYL1)	28%	100%
A7FD10	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	27%	100%
A7ZUI2	Escherichia coli O139:H28 (strain E24377A / ETEC)	26%	100%
A8A770	Escherichia coli O9:H4 (strain HS)	26%	100%
A8AKW0	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	27%	100%
A8GL77	Serratia proteamaculans (strain 568)	27%	100%
A8MS68	Arabidopsis thaliana	24%	100%
A9N0H2	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	26%	100%
A9R6N5	Yersinia pestis bv. Antiqua (strain Angola)	27%	100%
B0KH90	Pseudomonas putida (strain GB-1)	26%	100%
B1IVB6	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	26%	100%
B1J606	Pseudomonas putida (strain W619)	26%	100%
B1JQ50	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	27%	100%
B1LNS2	Escherichia coli (strain SMS-3-5 / SECEC)	26%	100%
B1XBX3	Escherichia coli (strain K12 / DH10B)	26%	100%
B2JZF3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	27%	100%
B2TWF7	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	26%	100%
B2VGA0	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	27%	100%
B4F1H1	Proteus mirabilis (strain HI4320)	28%	100%
B5BJN6	Salmonella paratyphi A (strain AKU_12601)	26%	100%
B5QXQ7	Salmonella enteritidis PT4 (strain P125109)	26%	100%
B5REZ6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	26%	100%
B5XZ14	Klebsiella pneumoniae (strain 342)	27%	100%
B5Z064	Escherichia coli O157:H7 (strain EC4115 / EHEC)	26%	100%
B6I5I0	Escherichia coli (strain SE11)	26%	100%
B7LA64	Escherichia coli (strain 55989 / EAEC)	26%	100%
B7LUN3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	26%	100%
B7M718	Escherichia coli O8 (strain IAI1)	26%	100%
B7MIA0	Escherichia coli O45:K1 (strain S88 / ExPEC)	26%	100%
B7MR55	Escherichia coli O81 (strain ED1a)	26%	100%
B7NFR2	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	26%	100%
B7NU38	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	26%	100%
B7UNU0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	26%	100%
B7UZU5	Pseudomonas aeruginosa (strain LESB58)	27%	100%
B7VM91	Vibrio atlanticus (strain LGP32)	27%	100%
B9A1H3	Emiliania huxleyi	24%	100%
C0Q478	Salmonella paratyphi C (strain RKS4594)	26%	100%
C1AFH2	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	28%	100%
C1DR10	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	26%	100%
C3K4W1	Pseudomonas fluorescens (strain SBW25)	26%	100%
C3LPZ2	Vibrio cholerae serotype O1 (strain M66-2)	28%	100%
C4K3I8	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	28%	100%
C5A0R1	Escherichia coli (strain K12 / MC4100 / BW2952)	26%	100%
C9ZLC8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZMF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
C9ZWN2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
D0A4H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0AAR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
D0VWY5	Marichromatium gracile	26%	100%
E9AE44	Leishmania major	39%	100%
E9AHL8	Leishmania infantum	35%	100%
E9AKE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
E9ALP1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9B263	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
E9B264	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B3B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
F4JLP5	Arabidopsis thaliana	24%	100%
G0SB20	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	27%	100%
O00087	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
O04955	Brassica rapa subsp. pekinensis	26%	100%
O05139	Pseudomonas fluorescens	26%	100%
O05940	Rhizobium etli (strain CFN 42 / ATCC 51251)	25%	100%
O08749	Mus musculus	26%	100%
O17953	Caenorhabditis elegans	26%	100%
O18480	Manduca sexta	24%	100%
O34324	Bacillus subtilis (strain 168)	26%	100%
O50286	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	27%	100%
O50311	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	28%	100%
O84561	Chlamydia trachomatis (strain D/UW-3/Cx)	27%	100%
P00390	Homo sapiens	24%	100%
P00392	Pseudomonas aeruginosa	26%	100%
P08332	Shigella flexneri	27%	100%
P09063	Pseudomonas putida	28%	100%
P09622	Homo sapiens	26%	100%
P09623	Sus scrofa	26%	100%
P09624	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P0A0E4	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	25%	100%
P0A0E5	Staphylococcus aureus	25%	100%
P0A0E6	Staphylococcus aureus (strain Mu50 / ATCC 700699)	26%	100%
P0A0E7	Staphylococcus aureus (strain MW2)	26%	100%
P0A0E8	Staphylococcus aureus	26%	100%
P0A9P0	Escherichia coli (strain K12)	26%	100%
P0A9P1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
P0A9P2	Escherichia coli O157:H7	26%	100%
P0A9P3	Shigella flexneri	26%	100%
P11959	Geobacillus stearothermophilus	28%	100%
P13110	Trypanosoma congolense	24%	100%
P14218	Pseudomonas fluorescens	25%	100%
P16171	Bacillus cereus	25%	99%
P17239	Acidithiobacillus ferrooxidans	25%	100%
P18925	Azotobacter vinelandii	25%	100%
P21880	Bacillus subtilis (strain 168)	27%	100%
P23189	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
P27306	Escherichia coli (strain K12)	26%	100%
P27456	Pisum sativum	24%	100%
P28593	Trypanosoma cruzi	25%	100%
P30341	Streptomyces lividans	27%	100%
P30635	Caenorhabditis elegans	26%	100%
P31023	Pisum sativum	26%	100%
P31046	Pseudomonas putida	29%	100%
P31052	Pseudomonas putida	25%	100%
P39040	Crithidia fasciculata	23%	100%
P39050	Leishmania donovani	22%	100%
P39051	Trypanosoma brucei brucei	25%	100%
P41921	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P42770	Arabidopsis thaliana	25%	100%
P43784	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	26%	100%
P47513	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	25%	100%
P47791	Mus musculus	24%	100%
P48638	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	28%	100%
P48639	Burkholderia cepacia	30%	100%
P48640	Glycine max	24%	100%
P48641	Arabidopsis thaliana	26%	100%
P48642	Oryza sativa subsp. japonica	24%	100%
P49819	Canis lupus familiaris	25%	100%
P50529	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	28%	100%
P50970	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	27%	100%
P52992	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	26%	100%
P54533	Bacillus subtilis (strain 168)	28%	100%
P57112	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	27%	100%
P57303	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	26%	100%
P61076	Plasmodium falciparum (isolate 3D7)	24%	100%
P66005	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	27%	100%
P66007	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	28%	100%
P66008	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	26%	100%
P66009	Salmonella typhi	26%	100%
P72740	Synechocystis sp. (strain PCC 6803 / Kazusa)	27%	100%
P75393	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	24%	100%
P77212	Escherichia coli (strain K12)	25%	100%
P80461	Nicotiana tabacum	25%	100%
P85207	Thermus scotoductus (strain ATCC 700910 / SA-01)	27%	100%
P90597	Trypanosoma cruzi	27%	100%
P91938	Drosophila melanogaster	23%	100%
P94188	Alcaligenes sp.	25%	100%
P94702	Enterobacter agglomerans	26%	100%
P95596	Rhodobacter capsulatus	27%	100%
P99084	Staphylococcus aureus (strain N315)	26%	100%
P9WHH2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	100%
P9WHH3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	100%
P9WHH4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	28%	100%
P9WHH5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	28%	100%
P9WHH6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	100%
P9WHH7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	100%
P9WHH8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	27%	100%
P9WHH9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	27%	100%
Q02733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
Q02PF5	Pseudomonas aeruginosa (strain UCBPP-PA14)	27%	100%
Q04829	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	27%	100%
Q04933	Trypanosoma brucei brucei	27%	100%
Q0TA96	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	26%	100%
Q16881	Homo sapiens	24%	96%
Q1CBU5	Yersinia pestis bv. Antiqua (strain Antiqua)	27%	100%
Q1CNP4	Yersinia pestis bv. Antiqua (strain Nepal516)	27%	100%
Q1I7F0	Pseudomonas entomophila (strain L48)	26%	100%
Q1QX78	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	27%	100%
Q1R3U7	Escherichia coli (strain UTI89 / UPEC)	26%	100%
Q25861	Plasmodium falciparum (isolate FCH-5)	23%	100%
Q2NQZ3	Sodalis glossinidius (strain morsitans)	26%	100%
Q2SIP2	Hahella chejuensis (strain KCTC 2396)	26%	100%
Q3K9F5	Pseudomonas fluorescens (strain Pf0-1)	27%	100%
Q41219	Glycine max	25%	100%
Q43154	Spinacia oleracea	28%	100%
Q43621	Pisum sativum	27%	100%
Q48A14	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	28%	100%
Q48KI8	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	26%	100%
Q4KFA6	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	27%	100%
Q4Q4U1	Leishmania major	25%	100%
Q4Q5Z6	Leishmania major	35%	100%
Q4Q5Z7	Leishmania major	93%	99%
Q4QJG7	Leishmania major	23%	100%
Q4ZV77	Pseudomonas syringae pv. syringae (strain B728a)	27%	100%
Q50068	Mycobacterium leprae (strain TN)	27%	100%
Q51772	Pseudomonas fluorescens	26%	100%
Q52109	Acinetobacter calcoaceticus	25%	100%
Q54465	Shewanella putrefaciens	26%	100%
Q54EW8	Dictyostelium discoideum	24%	100%
Q57H91	Salmonella choleraesuis (strain SC-B67)	26%	100%
Q5E212	Aliivibrio fischeri (strain ATCC 700601 / ES114)	26%	100%
Q5HGY8	Staphylococcus aureus (strain COL)	26%	100%
Q5NVA2	Pongo abelii	24%	100%
Q5PK71	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	26%	100%
Q5R4B1	Pongo abelii	26%	100%
Q5UWH2	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	29%	100%
Q5UYG6	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	28%	100%
Q60151	Streptococcus thermophilus	24%	100%
Q60HG3	Macaca fascicularis	26%	100%
Q66G61	Yersinia pseudotuberculosis serotype I (strain IP32953)	27%	100%
Q6CZB1	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	28%	100%
Q6GAB8	Staphylococcus aureus (strain MSSA476)	26%	100%
Q6GHY9	Staphylococcus aureus (strain MRSA252)	26%	100%
Q6HA23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	25%	100%
Q6LLT9	Photobacterium profundum (strain SS9)	27%	100%
Q6P6R2	Rattus norvegicus	26%	100%
Q7MBG9	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	27%	100%
Q7MQ83	Vibrio vulnificus (strain YJ016)	28%	100%
Q811C4	Mesocricetus auratus	26%	100%
Q83MI1	Shigella flexneri	26%	100%
Q86VQ6	Homo sapiens	23%	97%
Q87KN5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	29%	100%
Q884I6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	26%	100%
Q88KY8	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	26%	100%
Q89AQ8	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	25%	100%
Q8CIZ7	Cricetulus griseus	26%	100%
Q8DD46	Vibrio vulnificus (strain CMCP6)	28%	100%
Q8FB93	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	26%	100%
Q8K9T7	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	26%	100%
Q8KCW2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	28%	100%
Q8NTE1	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	25%	100%
Q8X727	Escherichia coli O157:H7	26%	100%
Q8ZA97	Yersinia pestis	27%	100%
Q99MD6	Mus musculus	24%	96%
Q9HN74	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	27%	100%
Q9HUY1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	30%	100%
Q9I1L9	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	27%	100%
Q9I3D1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	25%	100%
Q9JLT4	Mus musculus	25%	100%
Q9KPF6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	27%	100%
Q9M5K2	Arabidopsis thaliana	25%	100%
Q9M5K3	Arabidopsis thaliana	26%	100%
Q9N2I8	Bos taurus	26%	100%
Q9NNW7	Homo sapiens	25%	100%
Q9PJI3	Chlamydia muridarum (strain MoPn / Nigg)	26%	100%
Q9SPB1	Vigna unguiculata	25%	100%
Q9XBQ9	Azotobacter vinelandii	26%	100%
Q9Z0J5	Rattus norvegicus	26%	100%
Q9Z773	Chlamydia pneumoniae	25%	100%
V5AJG2	Trypanosoma cruzi	25%	100%
V5B6P6	Trypanosoma cruzi	47%	100%
V5BB90	Trypanosoma cruzi	37%	100%
V5BDX2	Trypanosoma cruzi	39%	100%
V5BVJ1	Trypanosoma cruzi	27%	100%