Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X4V8_LEIDO

TriTrypDb:

LdBPK_312490.1 , LdCL_310032900 , LDHU3_31.4480

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X4V8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4V8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	27	31	PF00656	0.560
CLV_MEL_PAP_1	92	98	PF00089	0.587
CLV_NRD_NRD_1	66	68	PF00675	0.611
CLV_PCSK_FUR_1	64	68	PF00082	0.611
CLV_PCSK_KEX2_1	66	68	PF00082	0.611
CLV_PCSK_KEX2_1	94	96	PF00082	0.799
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.716
DEG_SPOP_SBC_1	125	129	PF00917	0.780
DEG_SPOP_SBC_1	136	140	PF00917	0.580
DOC_CYCLIN_yClb3_PxF_3	83	89	PF00134	0.722
DOC_CYCLIN_yCln2_LP_2	78	84	PF00134	0.810
DOC_PP2B_LxvP_1	42	45	PF13499	0.633
DOC_USP7_MATH_1	125	129	PF00917	0.630
DOC_USP7_MATH_1	132	136	PF00917	0.581
DOC_USP7_MATH_1	153	157	PF00917	0.788
DOC_USP7_MATH_1	52	56	PF00917	0.657
DOC_WW_Pin1_4	70	75	PF00397	0.734
LIG_BIR_II_1	1	5	PF00653	0.815
LIG_BIR_III_2	30	34	PF00653	0.583
LIG_FHA_1	118	124	PF00498	0.687
LIG_FHA_1	136	142	PF00498	0.467
LIG_LIR_Gen_1	140	151	PF02991	0.686
LIG_LIR_Gen_1	55	60	PF02991	0.618
LIG_LIR_Gen_1	88	96	PF02991	0.679
LIG_LIR_Gen_1	98	105	PF02991	0.530
LIG_LIR_Nem_3	140	146	PF02991	0.567
LIG_LIR_Nem_3	55	59	PF02991	0.617
LIG_LIR_Nem_3	88	92	PF02991	0.685
LIG_PDZ_Class_2	198	203	PF00595	0.709
LIG_SH2_STAT5	171	174	PF00017	0.669
LIG_SH3_3	42	48	PF00018	0.647
LIG_SH3_3	78	84	PF00018	0.727
LIG_WRC_WIRS_1	53	58	PF05994	0.618
LIG_WRC_WIRS_1	96	101	PF05994	0.691
LIG_WW_3	73	77	PF00397	0.812
MOD_CDC14_SPxK_1	73	76	PF00782	0.810
MOD_CDK_SPxK_1	70	76	PF00069	0.814
MOD_CK1_1	107	113	PF00069	0.666
MOD_CK1_1	124	130	PF00069	0.469
MOD_CK1_1	135	141	PF00069	0.571
MOD_CK1_1	55	61	PF00069	0.676
MOD_Cter_Amidation	64	67	PF01082	0.608
MOD_GlcNHglycan	123	126	PF01048	0.631
MOD_GlcNHglycan	49	52	PF01048	0.718
MOD_GSK3_1	104	111	PF00069	0.645
MOD_GSK3_1	117	124	PF00069	0.622
MOD_GSK3_1	132	139	PF00069	0.507
MOD_GSK3_1	55	62	PF00069	0.717
MOD_GSK3_1	6	13	PF00069	0.789
MOD_GSK3_1	66	73	PF00069	0.568
MOD_NEK2_1	10	15	PF00069	0.666
MOD_NEK2_1	108	113	PF00069	0.775
MOD_NEK2_1	121	126	PF00069	0.542
MOD_NEK2_1	59	64	PF00069	0.630
MOD_NEK2_2	52	57	PF00069	0.698
MOD_PIKK_1	82	88	PF00454	0.700
MOD_PKA_1	66	72	PF00069	0.611
MOD_PKA_2	66	72	PF00069	0.760
MOD_PKB_1	64	72	PF00069	0.694
MOD_Plk_1	116	122	PF00069	0.775
MOD_Plk_4	104	110	PF00069	0.778
MOD_Plk_4	55	61	PF00069	0.576
MOD_ProDKin_1	70	76	PF00069	0.735
MOD_SUMO_rev_2	174	181	PF00179	0.673
TRG_DiLeu_BaEn_1	104	109	PF01217	0.779
TRG_ER_diArg_1	64	67	PF00400	0.608

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HJM5	Leishmania braziliensis	64%	99%
A4I747	Leishmania infantum	99%	100%
E9B241	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%