Carries a conserved CRAL-TRIO domain. Its didtant homologs are cytoplasmic and are involved in antiviral response.
Source | Evidence on protein | Close homologs |
---|---|---|
Cuervo et al. | no | yes: 0 |
Hassani et al. | no | yes: 0 |
Forrest at al. (metacyclic) | no | yes: 0 |
Forrest at al. (procyclic) | no | yes: 0 |
Silverman et al. | no | yes: 0 |
Pissara et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Pires et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Silverman et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
Jamdhade et al. | no | yes: 0 |
Source | Evidence on protein | Close homologs |
---|---|---|
DeepLoc | ||
SignalP6 | no | yes: 0, no: 34 |
NetGPI | no | yes: 0, no: 34 |
Term | Name | Level | Count |
---|---|---|---|
GO:0005737 | cytoplasm | 2 | 1 |
GO:0110165 | cellular anatomical entity | 1 | 1 |
Related structures:
AlphaFold database: A0A3S7X4R1
Leishmania | From | To | Domain/Motif | Score |
---|---|---|---|---|
CLV_C14_Caspase3-7 | 56 | 60 | PF00656 | 0.551 |
CLV_NRD_NRD_1 | 299 | 301 | PF00675 | 0.296 |
CLV_NRD_NRD_1 | 32 | 34 | PF00675 | 0.440 |
CLV_PCSK_KEX2_1 | 34 | 36 | PF00082 | 0.401 |
CLV_PCSK_KEX2_1 | 387 | 389 | PF00082 | 0.310 |
CLV_PCSK_PC1ET2_1 | 34 | 36 | PF00082 | 0.431 |
CLV_PCSK_PC1ET2_1 | 387 | 389 | PF00082 | 0.381 |
CLV_PCSK_SKI1_1 | 179 | 183 | PF00082 | 0.310 |
CLV_PCSK_SKI1_1 | 23 | 27 | PF00082 | 0.440 |
CLV_PCSK_SKI1_1 | 232 | 236 | PF00082 | 0.333 |
CLV_PCSK_SKI1_1 | 250 | 254 | PF00082 | 0.337 |
CLV_PCSK_SKI1_1 | 291 | 295 | PF00082 | 0.382 |
CLV_PCSK_SKI1_1 | 387 | 391 | PF00082 | 0.360 |
CLV_PCSK_SKI1_1 | 41 | 45 | PF00082 | 0.341 |
CLV_Separin_Metazoa | 30 | 34 | PF03568 | 0.303 |
DOC_MAPK_gen_1 | 300 | 307 | PF00069 | 0.360 |
DOC_MAPK_gen_1 | 85 | 94 | PF00069 | 0.462 |
DOC_MAPK_HePTP_8 | 243 | 255 | PF00069 | 0.294 |
DOC_MAPK_MEF2A_6 | 159 | 167 | PF00069 | 0.326 |
DOC_MAPK_MEF2A_6 | 232 | 240 | PF00069 | 0.358 |
DOC_MAPK_MEF2A_6 | 246 | 255 | PF00069 | 0.441 |
DOC_MAPK_MEF2A_6 | 87 | 96 | PF00069 | 0.441 |
DOC_PP4_FxxP_1 | 66 | 69 | PF00568 | 0.286 |
DOC_USP7_MATH_1 | 3 | 7 | PF00917 | 0.520 |
DOC_USP7_MATH_1 | 421 | 425 | PF00917 | 0.599 |
DOC_USP7_MATH_1 | 443 | 447 | PF00917 | 0.518 |
DOC_USP7_UBL2_3 | 246 | 250 | PF12436 | 0.479 |
DOC_USP7_UBL2_3 | 346 | 350 | PF12436 | 0.464 |
DOC_WW_Pin1_4 | 187 | 192 | PF00397 | 0.296 |
DOC_WW_Pin1_4 | 276 | 281 | PF00397 | 0.290 |
DOC_WW_Pin1_4 | 307 | 312 | PF00397 | 0.358 |
DOC_WW_Pin1_4 | 441 | 446 | PF00397 | 0.565 |
DOC_WW_Pin1_4 | 48 | 53 | PF00397 | 0.537 |
DOC_WW_Pin1_4 | 65 | 70 | PF00397 | 0.287 |
LIG_14-3-3_CanoR_1 | 141 | 149 | PF00244 | 0.445 |
LIG_14-3-3_CanoR_1 | 388 | 393 | PF00244 | 0.368 |
LIG_14-3-3_CanoR_1 | 85 | 90 | PF00244 | 0.440 |
LIG_Actin_WH2_2 | 371 | 389 | PF00022 | 0.312 |
LIG_Clathr_ClatBox_1 | 125 | 129 | PF01394 | 0.247 |
LIG_deltaCOP1_diTrp_1 | 82 | 89 | PF00928 | 0.466 |
LIG_eIF4E_1 | 73 | 79 | PF01652 | 0.449 |
LIG_FHA_1 | 149 | 155 | PF00498 | 0.485 |
LIG_FHA_1 | 188 | 194 | PF00498 | 0.449 |
LIG_FHA_1 | 233 | 239 | PF00498 | 0.309 |
LIG_FHA_1 | 24 | 30 | PF00498 | 0.443 |
LIG_FHA_1 | 357 | 363 | PF00498 | 0.648 |
LIG_FHA_1 | 373 | 379 | PF00498 | 0.404 |
LIG_FHA_1 | 412 | 418 | PF00498 | 0.402 |
LIG_FHA_1 | 425 | 431 | PF00498 | 0.334 |
LIG_FHA_2 | 346 | 352 | PF00498 | 0.719 |
LIG_FHA_2 | 451 | 457 | PF00498 | 0.395 |
LIG_FHA_2 | 54 | 60 | PF00498 | 0.619 |
LIG_LIR_Apic_2 | 413 | 418 | PF02991 | 0.433 |
LIG_LIR_Apic_2 | 65 | 69 | PF02991 | 0.286 |
LIG_LIR_Gen_1 | 397 | 405 | PF02991 | 0.372 |
LIG_LIR_Gen_1 | 457 | 465 | PF02991 | 0.438 |
LIG_LIR_Gen_1 | 88 | 96 | PF02991 | 0.447 |
LIG_LIR_Nem_3 | 12 | 17 | PF02991 | 0.618 |
LIG_LIR_Nem_3 | 147 | 152 | PF02991 | 0.395 |
LIG_LIR_Nem_3 | 244 | 248 | PF02991 | 0.354 |
LIG_LIR_Nem_3 | 262 | 267 | PF02991 | 0.364 |
LIG_LIR_Nem_3 | 397 | 403 | PF02991 | 0.338 |
LIG_LIR_Nem_3 | 409 | 415 | PF02991 | 0.371 |
LIG_LIR_Nem_3 | 457 | 463 | PF02991 | 0.448 |
LIG_LIR_Nem_3 | 65 | 70 | PF02991 | 0.468 |
LIG_LYPXL_SIV_4 | 286 | 294 | PF13949 | 0.319 |
LIG_LYPXL_yS_3 | 14 | 17 | PF13949 | 0.373 |
LIG_MAD2 | 123 | 131 | PF02301 | 0.243 |
LIG_OCRL_FandH_1 | 470 | 482 | PF00620 | 0.290 |
LIG_PCNA_PIPBox_1 | 195 | 204 | PF02747 | 0.266 |
LIG_PCNA_PIPBox_1 | 257 | 266 | PF02747 | 0.196 |
LIG_Pex14_2 | 412 | 416 | PF04695 | 0.325 |
LIG_Pex14_2 | 460 | 464 | PF04695 | 0.221 |
LIG_PTB_Apo_2 | 69 | 76 | PF02174 | 0.245 |
LIG_PTB_Phospho_1 | 69 | 75 | PF10480 | 0.245 |
LIG_SH2_CRK | 287 | 291 | PF00017 | 0.367 |
LIG_SH2_CRK | 36 | 40 | PF00017 | 0.459 |
LIG_SH2_CRK | 49 | 53 | PF00017 | 0.541 |
LIG_SH2_GRB2like | 166 | 169 | PF00017 | 0.446 |
LIG_SH2_SRC | 341 | 344 | PF00017 | 0.456 |
LIG_SH2_STAT5 | 149 | 152 | PF00017 | 0.341 |
LIG_SH2_STAT5 | 166 | 169 | PF00017 | 0.278 |
LIG_SH2_STAT5 | 322 | 325 | PF00017 | 0.382 |
LIG_SH2_STAT5 | 326 | 329 | PF00017 | 0.378 |
LIG_SH2_STAT5 | 415 | 418 | PF00017 | 0.389 |
LIG_SH2_STAT5 | 438 | 441 | PF00017 | 0.498 |
LIG_SH2_STAT5 | 452 | 455 | PF00017 | 0.338 |
LIG_SH2_STAT5 | 73 | 76 | PF00017 | 0.365 |
LIG_SH3_3 | 128 | 134 | PF00018 | 0.480 |
LIG_SH3_3 | 169 | 175 | PF00018 | 0.223 |
LIG_SH3_3 | 274 | 280 | PF00018 | 0.361 |
LIG_SUMO_SIM_anti_2 | 26 | 33 | PF11976 | 0.243 |
LIG_SUMO_SIM_par_1 | 124 | 129 | PF11976 | 0.236 |
LIG_SUMO_SIM_par_1 | 233 | 239 | PF11976 | 0.352 |
LIG_SUMO_SIM_par_1 | 273 | 279 | PF11976 | 0.210 |
LIG_TRAF2_1 | 19 | 22 | PF00917 | 0.392 |
LIG_TRAF2_1 | 382 | 385 | PF00917 | 0.464 |
LIG_TYR_ITIM | 164 | 169 | PF00017 | 0.369 |
LIG_TYR_ITIM | 243 | 248 | PF00017 | 0.399 |
LIG_UBA3_1 | 125 | 130 | PF00899 | 0.247 |
LIG_UBA3_1 | 177 | 182 | PF00899 | 0.403 |
LIG_UBA3_1 | 28 | 34 | PF00899 | 0.521 |
LIG_UBA3_1 | 459 | 467 | PF00899 | 0.235 |
LIG_WRC_WIRS_1 | 149 | 154 | PF05994 | 0.196 |
LIG_WRC_WIRS_1 | 63 | 68 | PF05994 | 0.516 |
MOD_CDC14_SPxK_1 | 68 | 71 | PF00782 | 0.260 |
MOD_CDK_SPxK_1 | 65 | 71 | PF00069 | 0.278 |
MOD_CK1_1 | 357 | 363 | PF00069 | 0.644 |
MOD_CK1_1 | 424 | 430 | PF00069 | 0.472 |
MOD_CK1_1 | 441 | 447 | PF00069 | 0.483 |
MOD_CK1_1 | 469 | 475 | PF00069 | 0.390 |
MOD_CK2_1 | 103 | 109 | PF00069 | 0.273 |
MOD_CK2_1 | 168 | 174 | PF00069 | 0.434 |
MOD_CK2_1 | 345 | 351 | PF00069 | 0.547 |
MOD_CK2_1 | 430 | 436 | PF00069 | 0.458 |
MOD_CK2_1 | 441 | 447 | PF00069 | 0.381 |
MOD_CK2_1 | 48 | 54 | PF00069 | 0.485 |
MOD_CK2_1 | 94 | 100 | PF00069 | 0.301 |
MOD_GlcNHglycan | 111 | 114 | PF01048 | 0.452 |
MOD_GlcNHglycan | 142 | 145 | PF01048 | 0.366 |
MOD_GlcNHglycan | 232 | 235 | PF01048 | 0.196 |
MOD_GlcNHglycan | 351 | 354 | PF01048 | 0.675 |
MOD_GlcNHglycan | 363 | 366 | PF01048 | 0.647 |
MOD_GlcNHglycan | 403 | 406 | PF01048 | 0.449 |
MOD_GSK3_1 | 345 | 352 | PF00069 | 0.629 |
MOD_GSK3_1 | 357 | 364 | PF00069 | 0.602 |
MOD_GSK3_1 | 372 | 379 | PF00069 | 0.461 |
MOD_GSK3_1 | 421 | 428 | PF00069 | 0.398 |
MOD_GSK3_1 | 446 | 453 | PF00069 | 0.384 |
MOD_GSK3_1 | 481 | 488 | PF00069 | 0.410 |
MOD_N-GLC_2 | 72 | 74 | PF02516 | 0.238 |
MOD_NEK2_1 | 230 | 235 | PF00069 | 0.356 |
MOD_NEK2_1 | 256 | 261 | PF00069 | 0.339 |
MOD_NEK2_1 | 349 | 354 | PF00069 | 0.582 |
MOD_NEK2_1 | 425 | 430 | PF00069 | 0.585 |
MOD_NEK2_1 | 481 | 486 | PF00069 | 0.469 |
MOD_NEK2_1 | 53 | 58 | PF00069 | 0.419 |
MOD_NEK2_1 | 92 | 97 | PF00069 | 0.347 |
MOD_NEK2_2 | 62 | 67 | PF00069 | 0.316 |
MOD_PK_1 | 394 | 400 | PF00069 | 0.261 |
MOD_PKA_2 | 132 | 138 | PF00069 | 0.495 |
MOD_PKA_2 | 140 | 146 | PF00069 | 0.376 |
MOD_Plk_1 | 376 | 382 | PF00069 | 0.478 |
MOD_Plk_4 | 232 | 238 | PF00069 | 0.333 |
MOD_Plk_4 | 259 | 265 | PF00069 | 0.425 |
MOD_Plk_4 | 394 | 400 | PF00069 | 0.383 |
MOD_Plk_4 | 411 | 417 | PF00069 | 0.417 |
MOD_Plk_4 | 430 | 436 | PF00069 | 0.484 |
MOD_Plk_4 | 466 | 472 | PF00069 | 0.367 |
MOD_Plk_4 | 62 | 68 | PF00069 | 0.529 |
MOD_ProDKin_1 | 187 | 193 | PF00069 | 0.296 |
MOD_ProDKin_1 | 276 | 282 | PF00069 | 0.290 |
MOD_ProDKin_1 | 307 | 313 | PF00069 | 0.358 |
MOD_ProDKin_1 | 441 | 447 | PF00069 | 0.569 |
MOD_ProDKin_1 | 48 | 54 | PF00069 | 0.552 |
MOD_ProDKin_1 | 65 | 71 | PF00069 | 0.284 |
MOD_SUMO_for_1 | 222 | 225 | PF00179 | 0.196 |
TRG_DiLeu_BaEn_1 | 24 | 29 | PF01217 | 0.376 |
TRG_ENDOCYTIC_2 | 14 | 17 | PF00928 | 0.598 |
TRG_ENDOCYTIC_2 | 149 | 152 | PF00928 | 0.380 |
TRG_ENDOCYTIC_2 | 166 | 169 | PF00928 | 0.340 |
TRG_ENDOCYTIC_2 | 212 | 215 | PF00928 | 0.372 |
TRG_ENDOCYTIC_2 | 245 | 248 | PF00928 | 0.372 |
TRG_ENDOCYTIC_2 | 287 | 290 | PF00928 | 0.376 |
TRG_ENDOCYTIC_2 | 36 | 39 | PF00928 | 0.467 |
TRG_ENDOCYTIC_2 | 75 | 78 | PF00928 | 0.334 |
TRG_ER_diArg_1 | 32 | 35 | PF00400 | 0.381 |
Protein | Taxonomy | Sequence identity | Coverage |
---|---|---|---|
A0A0N0P6D4 | Leptomonas seymouri | 38% | 94% |
A0A0N0P991 | Leptomonas seymouri | 29% | 100% |
A0A0N0P9K9 | Leptomonas seymouri | 25% | 100% |
A0A0N1I2J8 | Leptomonas seymouri | 42% | 100% |
A0A0N1PCS4 | Leptomonas seymouri | 50% | 100% |
A0A0S4J7N0 | Bodo saltans | 24% | 100% |
A0A0S4KJL3 | Bodo saltans | 28% | 100% |
A0A1X0NUH5 | Trypanosomatidae | 26% | 84% |
A0A1X0NUJ5 | Trypanosomatidae | 26% | 100% |
A0A3Q8ICN0 | Leishmania donovani | 51% | 100% |
A0A3Q8IGQ2 | Leishmania donovani | 32% | 97% |
A0A3R7MUL5 | Trypanosoma rangeli | 25% | 89% |
A0A3S7X4P4 | Leishmania donovani | 41% | 100% |
A0A422P1E3 | Trypanosoma rangeli | 27% | 100% |
A4HJI7 | Leishmania braziliensis | 41% | 100% |
A4HJI8 | Leishmania braziliensis | 76% | 100% |
A4HJI9 | Leishmania braziliensis | 51% | 100% |
A4HKB3 | Leishmania braziliensis | 32% | 99% |
A4HKB4 | Leishmania braziliensis | 24% | 100% |
A4I6Y2 | Leishmania infantum | 41% | 100% |
A4I6Y3 | Leishmania infantum | 99% | 100% |
A4I6Y4 | Leishmania infantum | 51% | 98% |
A4I7U3 | Leishmania infantum | 32% | 97% |
B5MCN3 | Homo sapiens | 21% | 100% |
E9B204 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 41% | 100% |
E9B205 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 91% | 100% |
E9B206 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 49% | 98% |
E9B2Q1 | Leishmania mexicana (strain MHOM/GT/2001/U1103) | 33% | 98% |
O17907 | Caenorhabditis elegans | 23% | 100% |
O76054 | Homo sapiens | 22% | 100% |
P58875 | Bos taurus | 21% | 100% |
Q03606 | Caenorhabditis elegans | 23% | 68% |
Q0V9N0 | Xenopus tropicalis | 23% | 69% |
Q16KN5 | Aedes aegypti | 23% | 76% |
Q4Q5F6 | Leishmania major | 33% | 98% |
Q4Q655 | Leishmania major | 49% | 100% |
Q4Q656 | Leishmania major | 93% | 100% |
Q4Q657 | Leishmania major | 41% | 100% |
Q8R0F9 | Mus musculus | 21% | 100% |
Q92503 | Homo sapiens | 22% | 69% |
Q99J08 | Mus musculus | 21% | 100% |
Q99MS0 | Rattus norvegicus | 21% | 100% |
Q9UDX3 | Homo sapiens | 23% | 100% |
Q9VMD6 | Drosophila melanogaster | 23% | 75% |
V5BL84 | Trypanosoma cruzi | 26% | 100% |
V5BQT0 | Trypanosoma cruzi | 25% | 89% |