Protein kinase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein kinase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X4H3_LEIDO

TriTrypDb:

LdBPK_311560.1 , LdCL_310022700 , LDHU3_31.2740

Length:

2283

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X4H3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	7
GO:0006793	phosphorus metabolic process	3	7
GO:0006796	phosphate-containing compound metabolic process	4	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016310	phosphorylation	5	7
GO:0018105	peptidyl-serine phosphorylation	6	1
GO:0018193	peptidyl-amino acid modification	5	1

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Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003824	catalytic activity	1	7
GO:0004672	protein kinase activity	3	7
GO:0004674	protein serine/threonine kinase activity	4	1
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1400	1404	PF00656	0.586
CLV_C14_Caspase3-7	1492	1496	PF00656	0.310
CLV_C14_Caspase3-7	1575	1579	PF00656	0.333
CLV_C14_Caspase3-7	185	189	PF00656	0.469
CLV_C14_Caspase3-7	2192	2196	PF00656	0.649
CLV_C14_Caspase3-7	775	779	PF00656	0.639
CLV_C14_Caspase3-7	897	901	PF00656	0.486
CLV_C14_Caspase3-7	990	994	PF00656	0.527
CLV_NRD_NRD_1	110	112	PF00675	0.431
CLV_NRD_NRD_1	168	170	PF00675	0.557

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4N0	Leptomonas seymouri	36%	100%
A4HJD4	Leishmania braziliensis	61%	98%
A4I6T1	Leishmania infantum	99%	100%
E9B1V3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4Q6A9	Leishmania major	87%	100%

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