LeishMANIAdb
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THO complex subunit 7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
THO complex subunit 7
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X4F2_LEIDO
TriTrypDb:
LdBPK_311380.1 * , LdCL_310020700 , LDHU3_31.2250
Length:
338

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X4F2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4F2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 294 298 PF00656 0.440
CLV_NRD_NRD_1 118 120 PF00675 0.518
CLV_NRD_NRD_1 246 248 PF00675 0.588
CLV_NRD_NRD_1 253 255 PF00675 0.547
CLV_NRD_NRD_1 64 66 PF00675 0.633
CLV_PCSK_FUR_1 251 255 PF00082 0.441
CLV_PCSK_FUR_1 62 66 PF00082 0.467
CLV_PCSK_KEX2_1 118 120 PF00082 0.499
CLV_PCSK_KEX2_1 207 209 PF00082 0.681
CLV_PCSK_KEX2_1 246 248 PF00082 0.616
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HXL4 Leptomonas seymouri 40% 100%
A0A422NZ65 Trypanosoma rangeli 29% 100%
A4HJB9 Leishmania braziliensis 73% 100%
A4I6R2 Leishmania infantum 100% 100%
C9ZWT4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
E9B1T4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4Q6C7 Leishmania major 91% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS