Proteophosphoglycan ppg4

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X4C6_LEIDO

TriTrypDb:

LdBPK_311080.1 , LdCL_310017400 , LDHU3_31.1800

Length:

978

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X4C6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4C6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.523
CLV_C14_Caspase3-7	237	241	PF00656	0.528
CLV_NRD_NRD_1	130	132	PF00675	0.775
CLV_NRD_NRD_1	136	138	PF00675	0.619
CLV_NRD_NRD_1	157	159	PF00675	0.395
CLV_NRD_NRD_1	37	39	PF00675	0.670
CLV_NRD_NRD_1	70	72	PF00675	0.817
CLV_NRD_NRD_1	87	89	PF00675	0.783
CLV_NRD_NRD_1	95	97	PF00675	0.684
CLV_NRD_NRD_1	970	972	PF00675	0.697
CLV_NRD_NRD_1	976	978	PF00675	0.662
CLV_PCSK_FUR_1	67	71	PF00082	0.636
CLV_PCSK_KEX2_1	130	132	PF00082	0.775
CLV_PCSK_KEX2_1	135	137	PF00082	0.648
CLV_PCSK_KEX2_1	157	159	PF00082	0.395
CLV_PCSK_KEX2_1	37	39	PF00082	0.713
CLV_PCSK_KEX2_1	69	71	PF00082	0.826
CLV_PCSK_KEX2_1	87	89	PF00082	0.783
CLV_PCSK_KEX2_1	95	97	PF00082	0.684
CLV_PCSK_KEX2_1	976	978	PF00082	0.722
CLV_PCSK_PC7_1	131	137	PF00082	0.556
CLV_PCSK_PC7_1	153	159	PF00082	0.391
CLV_PCSK_SKI1_1	225	229	PF00082	0.569
CLV_PCSK_SKI1_1	922	926	PF00082	0.710
DEG_SPOP_SBC_1	274	278	PF00917	0.612
DEG_SPOP_SBC_1	287	291	PF00917	0.581
DEG_SPOP_SBC_1	437	441	PF00917	0.609
DEG_SPOP_SBC_1	487	491	PF00917	0.551
DEG_SPOP_SBC_1	552	556	PF00917	0.582
DEG_SPOP_SBC_1	585	589	PF00917	0.658
DEG_SPOP_SBC_1	624	628	PF00917	0.688
DEG_SPOP_SBC_1	727	731	PF00917	0.596
DOC_CKS1_1	395	400	PF01111	0.633
DOC_CKS1_1	498	503	PF01111	0.634
DOC_MAPK_gen_1	187	195	PF00069	0.478
DOC_MAPK_MEF2A_6	187	195	PF00069	0.528
DOC_MAPK_MEF2A_6	3	10	PF00069	0.649
DOC_PP4_FxxP_1	391	394	PF00568	0.678
DOC_PP4_FxxP_1	395	398	PF00568	0.630
DOC_PP4_FxxP_1	740	743	PF00568	0.627
DOC_PP4_FxxP_1	932	935	PF00568	0.693
DOC_PP4_MxPP_1	794	797	PF00568	0.653
DOC_USP7_MATH_1	112	116	PF00917	0.757
DOC_USP7_MATH_1	263	267	PF00917	0.665
DOC_USP7_MATH_1	272	276	PF00917	0.649
DOC_USP7_MATH_1	287	291	PF00917	0.562
DOC_USP7_MATH_1	319	323	PF00917	0.707
DOC_USP7_MATH_1	324	328	PF00917	0.652
DOC_USP7_MATH_1	400	404	PF00917	0.626
DOC_USP7_MATH_1	433	437	PF00917	0.701
DOC_USP7_MATH_1	445	449	PF00917	0.581
DOC_USP7_MATH_1	451	455	PF00917	0.545
DOC_USP7_MATH_1	462	466	PF00917	0.582
DOC_USP7_MATH_1	482	486	PF00917	0.551
DOC_USP7_MATH_1	488	492	PF00917	0.629
DOC_USP7_MATH_1	496	500	PF00917	0.580
DOC_USP7_MATH_1	503	507	PF00917	0.542
DOC_USP7_MATH_1	517	521	PF00917	0.546
DOC_USP7_MATH_1	537	541	PF00917	0.513
DOC_USP7_MATH_1	557	561	PF00917	0.587
DOC_USP7_MATH_1	657	661	PF00917	0.639
DOC_USP7_MATH_1	662	666	PF00917	0.657
DOC_USP7_MATH_1	673	677	PF00917	0.549
DOC_USP7_MATH_1	700	704	PF00917	0.666
DOC_USP7_MATH_1	716	720	PF00917	0.608
DOC_USP7_MATH_1	727	731	PF00917	0.578
DOC_USP7_MATH_1	732	736	PF00917	0.531
DOC_USP7_MATH_1	751	755	PF00917	0.513
DOC_USP7_MATH_1	868	872	PF00917	0.666
DOC_USP7_MATH_1	878	882	PF00917	0.618
DOC_USP7_MATH_1	920	924	PF00917	0.665
DOC_USP7_UBL2_3	355	359	PF12436	0.646
DOC_WW_Pin1_4	261	266	PF00397	0.729
DOC_WW_Pin1_4	270	275	PF00397	0.713
DOC_WW_Pin1_4	277	282	PF00397	0.603
DOC_WW_Pin1_4	322	327	PF00397	0.705
DOC_WW_Pin1_4	382	387	PF00397	0.653
DOC_WW_Pin1_4	394	399	PF00397	0.662
DOC_WW_Pin1_4	497	502	PF00397	0.640
DOC_WW_Pin1_4	523	528	PF00397	0.667
DOC_WW_Pin1_4	533	538	PF00397	0.555
DOC_WW_Pin1_4	553	558	PF00397	0.604
DOC_WW_Pin1_4	564	569	PF00397	0.608
DOC_WW_Pin1_4	625	630	PF00397	0.717
DOC_WW_Pin1_4	651	656	PF00397	0.653
DOC_WW_Pin1_4	696	701	PF00397	0.608
DOC_WW_Pin1_4	735	740	PF00397	0.666
DOC_WW_Pin1_4	910	915	PF00397	0.711
DOC_WW_Pin1_4	936	941	PF00397	0.702
DOC_WW_Pin1_4	96	101	PF00397	0.754
LIG_14-3-3_CanoR_1	101	107	PF00244	0.732
LIG_14-3-3_CanoR_1	37	43	PF00244	0.673
LIG_14-3-3_CanoR_1	53	57	PF00244	0.539
LIG_14-3-3_CanoR_1	87	91	PF00244	0.685
LIG_BIR_II_1	1	5	PF00653	0.663
LIG_BRCT_BRCA1_1	145	149	PF00533	0.546
LIG_BRCT_BRCA1_1	290	294	PF00533	0.658
LIG_BRCT_BRCA1_1	445	449	PF00533	0.608
LIG_BRCT_BRCA1_1	488	492	PF00533	0.695
LIG_BRCT_BRCA1_1	614	618	PF00533	0.663
LIG_BRCT_BRCA1_1	697	701	PF00533	0.664
LIG_BRCT_BRCA1_1	718	722	PF00533	0.700
LIG_BRCT_BRCA1_1	736	740	PF00533	0.510
LIG_BRCT_BRCA1_1	769	773	PF00533	0.682
LIG_BRCT_BRCA1_1	865	869	PF00533	0.696
LIG_BRCT_BRCA1_1	938	942	PF00533	0.708
LIG_EH_1	392	396	PF12763	0.692
LIG_EH_1	406	410	PF12763	0.592
LIG_EH_1	544	548	PF12763	0.710
LIG_EVH1_1	395	399	PF00568	0.572
LIG_FHA_1	165	171	PF00498	0.528
LIG_FHA_1	339	345	PF00498	0.587
LIG_FHA_1	347	353	PF00498	0.565
LIG_FHA_1	470	476	PF00498	0.642
LIG_FHA_1	960	966	PF00498	0.697
LIG_FHA_2	103	109	PF00498	0.597
LIG_FHA_2	119	125	PF00498	0.621
LIG_FHA_2	370	376	PF00498	0.670
LIG_FHA_2	426	432	PF00498	0.587
LIG_IRF3_LxIS_1	224	230	PF10401	0.428
LIG_LIR_Apic_2	390	394	PF02991	0.671
LIG_LIR_Apic_2	737	743	PF02991	0.622
LIG_LIR_Gen_1	197	206	PF02991	0.627
LIG_LIR_Gen_1	248	256	PF02991	0.414
LIG_LIR_Gen_1	489	498	PF02991	0.653
LIG_LIR_Nem_3	11	16	PF02991	0.680
LIG_LIR_Nem_3	197	202	PF02991	0.629
LIG_LIR_Nem_3	248	252	PF02991	0.403
LIG_LIR_Nem_3	446	452	PF02991	0.586
LIG_LIR_Nem_3	489	495	PF02991	0.654
LIG_LIR_Nem_3	615	621	PF02991	0.661
LIG_PCNA_yPIPBox_3	153	166	PF02747	0.520
LIG_Pex14_2	391	395	PF04695	0.681
LIG_Pex14_2	740	744	PF04695	0.630
LIG_SH2_CRK	199	203	PF00017	0.621
LIG_SH2_NCK_1	199	203	PF00017	0.621
LIG_SH2_STAP1	199	203	PF00017	0.546
LIG_SH3_3	278	284	PF00018	0.661
LIG_SH3_3	28	34	PF00018	0.687
LIG_SH3_3	383	389	PF00018	0.583
LIG_SH3_3	393	399	PF00018	0.545
LIG_SH3_3	495	501	PF00018	0.648
LIG_SH3_3	543	549	PF00018	0.708
LIG_SH3_3	618	624	PF00018	0.711
LIG_SH3_3	793	799	PF00018	0.643
LIG_SH3_3	94	100	PF00018	0.597
LIG_SH3_4	355	362	PF00018	0.649
LIG_SUMO_SIM_anti_2	102	111	PF11976	0.704
MOD_CDK_SPK_2	382	387	PF00069	0.588
MOD_CDK_SPK_2	553	558	PF00069	0.622
MOD_CDK_SPK_2	96	101	PF00069	0.629
MOD_CDK_SPxxK_3	96	103	PF00069	0.633
MOD_CK1_1	115	121	PF00069	0.576
MOD_CK1_1	201	207	PF00069	0.513
MOD_CK1_1	261	267	PF00069	0.610
MOD_CK1_1	273	279	PF00069	0.657
MOD_CK1_1	289	295	PF00069	0.551
MOD_CK1_1	307	313	PF00069	0.504
MOD_CK1_1	322	328	PF00069	0.567
MOD_CK1_1	36	42	PF00069	0.636
MOD_CK1_1	380	386	PF00069	0.717
MOD_CK1_1	4	10	PF00069	0.707
MOD_CK1_1	436	442	PF00069	0.666
MOD_CK1_1	48	54	PF00069	0.673
MOD_CK1_1	507	513	PF00069	0.672
MOD_CK1_1	526	532	PF00069	0.515
MOD_CK1_1	580	586	PF00069	0.712
MOD_CK1_1	596	602	PF00069	0.565
MOD_CK1_1	610	616	PF00069	0.595
MOD_CK1_1	642	648	PF00069	0.704
MOD_CK1_1	665	671	PF00069	0.694
MOD_CK1_1	674	680	PF00069	0.608
MOD_CK1_1	692	698	PF00069	0.535
MOD_CK1_1	703	709	PF00069	0.669
MOD_CK1_1	735	741	PF00069	0.653
MOD_CK1_1	833	839	PF00069	0.690
MOD_CK1_1	863	869	PF00069	0.697
MOD_CK1_1	871	877	PF00069	0.603
MOD_CK1_1	959	965	PF00069	0.698
MOD_CK1_1	967	973	PF00069	0.620
MOD_CK1_1	99	105	PF00069	0.712
MOD_CK2_1	102	108	PF00069	0.598
MOD_CK2_1	191	197	PF00069	0.459
MOD_CK2_1	215	221	PF00069	0.530
MOD_CK2_1	227	233	PF00069	0.467
MOD_CK2_1	247	253	PF00069	0.458
MOD_CK2_1	348	354	PF00069	0.576
MOD_CK2_1	369	375	PF00069	0.675
MOD_DYRK1A_RPxSP_1	96	100	PF00069	0.748
MOD_GlcNHglycan	183	187	PF01048	0.453
MOD_GlcNHglycan	210	213	PF01048	0.487
MOD_GlcNHglycan	309	312	PF01048	0.637
MOD_GlcNHglycan	314	317	PF01048	0.628
MOD_GlcNHglycan	326	329	PF01048	0.552
MOD_GlcNHglycan	38	41	PF01048	0.685
MOD_GlcNHglycan	380	383	PF01048	0.656
MOD_GlcNHglycan	404	407	PF01048	0.609
MOD_GlcNHglycan	413	416	PF01048	0.614
MOD_GlcNHglycan	435	438	PF01048	0.670
MOD_GlcNHglycan	453	456	PF01048	0.569
MOD_GlcNHglycan	484	487	PF01048	0.618
MOD_GlcNHglycan	506	509	PF01048	0.709
MOD_GlcNHglycan	523	526	PF01048	0.526
MOD_GlcNHglycan	531	534	PF01048	0.580
MOD_GlcNHglycan	539	542	PF01048	0.527
MOD_GlcNHglycan	559	562	PF01048	0.552
MOD_GlcNHglycan	579	582	PF01048	0.674
MOD_GlcNHglycan	598	601	PF01048	0.539
MOD_GlcNHglycan	604	607	PF01048	0.683
MOD_GlcNHglycan	609	612	PF01048	0.621
MOD_GlcNHglycan	614	617	PF01048	0.530
MOD_GlcNHglycan	630	633	PF01048	0.557
MOD_GlcNHglycan	659	662	PF01048	0.632
MOD_GlcNHglycan	673	676	PF01048	0.600
MOD_GlcNHglycan	678	681	PF01048	0.552
MOD_GlcNHglycan	682	685	PF01048	0.623
MOD_GlcNHglycan	691	694	PF01048	0.530
MOD_GlcNHglycan	730	733	PF01048	0.638
MOD_GlcNHglycan	734	737	PF01048	0.588
MOD_GlcNHglycan	740	743	PF01048	0.589
MOD_GlcNHglycan	748	751	PF01048	0.538
MOD_GlcNHglycan	753	756	PF01048	0.509
MOD_GlcNHglycan	820	823	PF01048	0.645
MOD_GlcNHglycan	832	835	PF01048	0.600
MOD_GlcNHglycan	850	853	PF01048	0.534
MOD_GlcNHglycan	862	865	PF01048	0.572
MOD_GlcNHglycan	884	887	PF01048	0.693
MOD_GSK3_1	114	121	PF00069	0.702
MOD_GSK3_1	143	150	PF00069	0.545
MOD_GSK3_1	204	211	PF00069	0.477
MOD_GSK3_1	234	241	PF00069	0.540
MOD_GSK3_1	270	277	PF00069	0.673
MOD_GSK3_1	303	310	PF00069	0.677
MOD_GSK3_1	318	325	PF00069	0.571
MOD_GSK3_1	326	333	PF00069	0.619
MOD_GSK3_1	369	376	PF00069	0.699
MOD_GSK3_1	377	384	PF00069	0.664
MOD_GSK3_1	407	414	PF00069	0.614
MOD_GSK3_1	427	434	PF00069	0.522
MOD_GSK3_1	48	55	PF00069	0.761
MOD_GSK3_1	482	489	PF00069	0.676
MOD_GSK3_1	503	510	PF00069	0.635
MOD_GSK3_1	517	524	PF00069	0.538
MOD_GSK3_1	529	536	PF00069	0.586
MOD_GSK3_1	548	555	PF00069	0.517
MOD_GSK3_1	56	63	PF00069	0.623
MOD_GSK3_1	576	583	PF00069	0.712
MOD_GSK3_1	584	591	PF00069	0.648
MOD_GSK3_1	602	609	PF00069	0.576
MOD_GSK3_1	623	630	PF00069	0.692
MOD_GSK3_1	639	646	PF00069	0.545
MOD_GSK3_1	662	669	PF00069	0.693
MOD_GSK3_1	674	681	PF00069	0.576
MOD_GSK3_1	685	692	PF00069	0.581
MOD_GSK3_1	696	703	PF00069	0.657
MOD_GSK3_1	717	724	PF00069	0.660
MOD_GSK3_1	728	735	PF00069	0.579
MOD_GSK3_1	753	760	PF00069	0.617
MOD_GSK3_1	826	833	PF00069	0.578
MOD_GSK3_1	838	845	PF00069	0.581
MOD_GSK3_1	878	885	PF00069	0.582
MOD_GSK3_1	955	962	PF00069	0.692
MOD_LATS_1	371	377	PF00433	0.582
MOD_N-GLC_1	191	196	PF02516	0.467
MOD_N-GLC_1	377	382	PF02516	0.655
MOD_N-GLC_1	45	50	PF02516	0.714
MOD_N-GLC_1	607	612	PF02516	0.615
MOD_N-GLC_1	651	656	PF02516	0.648
MOD_N-GLC_1	695	700	PF02516	0.677
MOD_N-GLC_1	860	865	PF02516	0.695
MOD_N-GLC_2	299	301	PF02516	0.638
MOD_NEK2_1	1	6	PF00069	0.711
MOD_NEK2_1	165	170	PF00069	0.528
MOD_NEK2_1	191	196	PF00069	0.480
MOD_NEK2_1	206	211	PF00069	0.414
MOD_NEK2_1	227	232	PF00069	0.697
MOD_NEK2_1	304	309	PF00069	0.541
MOD_NEK2_1	337	342	PF00069	0.668
MOD_NEK2_1	411	416	PF00069	0.702
MOD_NEK2_1	528	533	PF00069	0.660
MOD_NEK2_1	593	598	PF00069	0.698
MOD_NEK2_1	643	648	PF00069	0.706
MOD_NEK2_1	685	690	PF00069	0.596
MOD_NEK2_1	701	706	PF00069	0.614
MOD_NEK2_1	717	722	PF00069	0.584
MOD_NEK2_1	728	733	PF00069	0.583
MOD_NEK2_1	818	823	PF00069	0.613
MOD_NEK2_1	848	853	PF00069	0.664
MOD_NEK2_1	882	887	PF00069	0.660
MOD_NEK2_1	955	960	PF00069	0.638
MOD_NEK2_1	965	970	PF00069	0.660
MOD_NEK2_2	878	883	PF00069	0.676
MOD_NEK2_2	920	925	PF00069	0.566
MOD_PIKK_1	1	7	PF00454	0.658
MOD_PIKK_1	930	936	PF00454	0.668
MOD_PIKK_1	956	962	PF00454	0.643
MOD_PK_1	198	204	PF00069	0.465
MOD_PKA_2	102	108	PF00069	0.737
MOD_PKA_2	238	244	PF00069	0.516
MOD_PKA_2	36	42	PF00069	0.668
MOD_PKA_2	52	58	PF00069	0.555
MOD_PKA_2	86	92	PF00069	0.645
MOD_PKB_1	135	143	PF00069	0.471
MOD_PKB_1	71	79	PF00069	0.590
MOD_Plk_1	115	121	PF00069	0.703
MOD_Plk_1	191	197	PF00069	0.469
MOD_Plk_1	215	221	PF00069	0.530
MOD_Plk_1	51	57	PF00069	0.683
MOD_Plk_1	73	79	PF00069	0.563
MOD_Plk_4	102	108	PF00069	0.719
MOD_Plk_4	198	204	PF00069	0.465
MOD_Plk_4	238	244	PF00069	0.547
MOD_Plk_4	462	468	PF00069	0.623
MOD_Plk_4	56	62	PF00069	0.721
MOD_Plk_4	768	774	PF00069	0.609
MOD_Plk_4	843	849	PF00069	0.707
MOD_Plk_4	878	884	PF00069	0.699
MOD_Plk_4	960	966	PF00069	0.704
MOD_ProDKin_1	261	267	PF00069	0.732
MOD_ProDKin_1	270	276	PF00069	0.714
MOD_ProDKin_1	277	283	PF00069	0.602
MOD_ProDKin_1	322	328	PF00069	0.707
MOD_ProDKin_1	382	388	PF00069	0.649
MOD_ProDKin_1	394	400	PF00069	0.661
MOD_ProDKin_1	497	503	PF00069	0.640
MOD_ProDKin_1	523	529	PF00069	0.671
MOD_ProDKin_1	533	539	PF00069	0.556
MOD_ProDKin_1	553	559	PF00069	0.606
MOD_ProDKin_1	564	570	PF00069	0.609
MOD_ProDKin_1	625	631	PF00069	0.716
MOD_ProDKin_1	651	657	PF00069	0.655
MOD_ProDKin_1	696	702	PF00069	0.608
MOD_ProDKin_1	735	741	PF00069	0.666
MOD_ProDKin_1	910	916	PF00069	0.711
MOD_ProDKin_1	936	942	PF00069	0.705
MOD_ProDKin_1	96	102	PF00069	0.755
MOD_SUMO_for_1	186	189	PF00179	0.509
MOD_SUMO_rev_2	230	237	PF00179	0.576
TRG_DiLeu_BaEn_4	215	221	PF01217	0.530
TRG_ENDOCYTIC_2	199	202	PF00928	0.620
TRG_ENDOCYTIC_2	203	206	PF00928	0.553
TRG_ER_diArg_1	100	103	PF00400	0.702
TRG_ER_diArg_1	134	137	PF00400	0.698
TRG_ER_diArg_1	29	32	PF00400	0.812
TRG_ER_diArg_1	66	69	PF00400	0.801
TRG_ER_diArg_1	70	73	PF00400	0.778
TRG_ER_diArg_1	95	97	PF00400	0.737
TRG_ER_diArg_1	975	977	PF00400	0.706
TRG_NES_CRM1_1	183	197	PF08389	0.530
TRG_NLS_MonoExtC_3	970	975	PF00514	0.692
TRG_Pf-PMV_PEXEL_1	88	93	PF00026	0.636

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HJ89	Leishmania braziliensis	65%	98%
A4I6N2	Leishmania infantum	99%	100%
E9B1Q5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%
Q4Q6F5	Leishmania major	86%	99%