Alba domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X4A5_LEIDO

TriTrypDb:

LdBPK_310990.1 , LdCL_310016500 , LDHU3_31.1670

Length:

419

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X4A5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4A5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0003677	DNA binding	4	3
GO:0005488	binding	1	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	254	258	PF00656	0.479
CLV_C14_Caspase3-7	411	415	PF00656	0.588
CLV_NRD_NRD_1	164	166	PF00675	0.582
CLV_NRD_NRD_1	196	198	PF00675	0.580
CLV_NRD_NRD_1	278	280	PF00675	0.587
CLV_NRD_NRD_1	333	335	PF00675	0.655
CLV_NRD_NRD_1	360	362	PF00675	0.609
CLV_NRD_NRD_1	378	380	PF00675	0.782
CLV_NRD_NRD_1	382	384	PF00675	0.644
CLV_PCSK_FUR_1	276	280	PF00082	0.584
CLV_PCSK_FUR_1	331	335	PF00082	0.636
CLV_PCSK_FUR_1	357	361	PF00082	0.600
CLV_PCSK_KEX2_1	162	164	PF00082	0.597
CLV_PCSK_KEX2_1	192	194	PF00082	0.573
CLV_PCSK_KEX2_1	196	198	PF00082	0.576
CLV_PCSK_KEX2_1	211	213	PF00082	0.545
CLV_PCSK_KEX2_1	278	280	PF00082	0.583
CLV_PCSK_KEX2_1	282	284	PF00082	0.580
CLV_PCSK_KEX2_1	331	333	PF00082	0.660
CLV_PCSK_KEX2_1	356	358	PF00082	0.731
CLV_PCSK_KEX2_1	359	361	PF00082	0.623
CLV_PCSK_KEX2_1	378	380	PF00082	0.628
CLV_PCSK_PC1ET2_1	162	164	PF00082	0.580
CLV_PCSK_PC1ET2_1	192	194	PF00082	0.573
CLV_PCSK_PC1ET2_1	211	213	PF00082	0.545
CLV_PCSK_PC1ET2_1	282	284	PF00082	0.600
CLV_PCSK_PC1ET2_1	356	358	PF00082	0.649
CLV_PCSK_PC7_1	158	164	PF00082	0.598
CLV_PCSK_PC7_1	274	280	PF00082	0.615
CLV_PCSK_SKI1_1	115	119	PF00082	0.411
CLV_PCSK_SKI1_1	223	227	PF00082	0.671
CLV_PCSK_SKI1_1	283	287	PF00082	0.577
CLV_PCSK_SKI1_1	336	340	PF00082	0.661
CLV_PCSK_SKI1_1	84	88	PF00082	0.427
DEG_Nend_Nbox_1	1	3	PF02207	0.509
DEG_SPOP_SBC_1	183	187	PF00917	0.570
DEG_SPOP_SBC_1	93	97	PF00917	0.417
DOC_CYCLIN_RxL_1	111	120	PF00134	0.407
DOC_MAPK_gen_1	192	203	PF00069	0.577
DOC_MAPK_gen_1	381	391	PF00069	0.579
DOC_MAPK_gen_1	91	100	PF00069	0.396
DOC_USP7_MATH_1	174	178	PF00917	0.529
DOC_USP7_MATH_1	206	210	PF00917	0.565
DOC_USP7_MATH_1	234	238	PF00917	0.513
DOC_USP7_MATH_1	248	252	PF00917	0.522
DOC_USP7_MATH_1	398	402	PF00917	0.718
DOC_USP7_MATH_1	407	411	PF00917	0.510
DOC_USP7_MATH_1	82	86	PF00917	0.381
DOC_USP7_MATH_1	93	97	PF00917	0.578
DOC_USP7_UBL2_3	162	166	PF12436	0.597
DOC_USP7_UBL2_3	188	192	PF12436	0.605
DOC_USP7_UBL2_3	207	211	PF12436	0.480
DOC_WW_Pin1_4	133	138	PF00397	0.536
DOC_WW_Pin1_4	156	161	PF00397	0.632
DOC_WW_Pin1_4	21	26	PF00397	0.459
DOC_WW_Pin1_4	308	313	PF00397	0.636
LIG_14-3-3_CanoR_1	12	19	PF00244	0.491
LIG_14-3-3_CanoR_1	199	204	PF00244	0.571
LIG_14-3-3_CanoR_1	223	232	PF00244	0.538
LIG_14-3-3_CanoR_1	276	286	PF00244	0.611
LIG_14-3-3_CanoR_1	44	53	PF00244	0.485
LIG_14-3-3_CanoR_1	70	77	PF00244	0.389
LIG_14-3-3_CanoR_1	94	99	PF00244	0.526
LIG_Actin_WH2_2	69	86	PF00022	0.410
LIG_BRCT_BRCA1_1	363	367	PF00533	0.585
LIG_BRCT_BRCA1_1	47	51	PF00533	0.419
LIG_CAP-Gly_1	414	419	PF01302	0.589
LIG_FHA_1	170	176	PF00498	0.573
LIG_FHA_1	178	184	PF00498	0.556
LIG_FHA_1	37	43	PF00498	0.393
LIG_FHA_1	93	99	PF00498	0.447
LIG_FHA_2	143	149	PF00498	0.642
LIG_FHA_2	224	230	PF00498	0.618
LIG_FHA_2	279	285	PF00498	0.594
LIG_FHA_2	297	303	PF00498	0.615
LIG_FHA_2	309	315	PF00498	0.526
LIG_FHA_2	345	351	PF00498	0.575
LIG_LIR_Gen_1	54	64	PF02991	0.411
LIG_LIR_Nem_3	301	307	PF02991	0.497
LIG_LIR_Nem_3	54	60	PF02991	0.415
LIG_PDZ_Class_2	414	419	PF00595	0.620
LIG_Rb_pABgroove_1	112	120	PF01858	0.390
LIG_SH2_NCK_1	307	311	PF00017	0.525
LIG_SH2_SRC	307	310	PF00017	0.519
LIG_SH2_STAP1	9	13	PF00017	0.365
LIG_SH3_1	266	272	PF00018	0.573
LIG_SH3_2	269	274	PF14604	0.611
LIG_SH3_3	134	140	PF00018	0.607
LIG_SH3_3	164	170	PF00018	0.587
LIG_SH3_3	188	194	PF00018	0.533
LIG_SH3_3	266	272	PF00018	0.604
LIG_SH3_4	405	412	PF00018	0.570
MOD_CDK_SPK_2	156	161	PF00069	0.564
MOD_CDK_SPxK_1	156	162	PF00069	0.563
MOD_CDK_SPxxK_3	156	163	PF00069	0.562
MOD_CK1_1	177	183	PF00069	0.515
MOD_CK1_1	21	27	PF00069	0.523
MOD_CK1_1	227	233	PF00069	0.620
MOD_CK1_1	34	40	PF00069	0.363
MOD_CK2_1	14	20	PF00069	0.391
MOD_CK2_1	142	148	PF00069	0.605
MOD_CK2_1	223	229	PF00069	0.552
MOD_CK2_1	278	284	PF00069	0.607
MOD_CK2_1	308	314	PF00069	0.569
MOD_CK2_1	344	350	PF00069	0.597
MOD_CK2_1	398	404	PF00069	0.643
MOD_Cter_Amidation	163	166	PF01082	0.567
MOD_Cter_Amidation	194	197	PF01082	0.555
MOD_Cter_Amidation	276	279	PF01082	0.619
MOD_Cter_Amidation	357	360	PF01082	0.583
MOD_Cter_Amidation	376	379	PF01082	0.526
MOD_GlcNHglycan	119	122	PF01048	0.502
MOD_GlcNHglycan	130	133	PF01048	0.406
MOD_GlcNHglycan	14	17	PF01048	0.436
MOD_GlcNHglycan	215	218	PF01048	0.590
MOD_GlcNHglycan	219	222	PF01048	0.577
MOD_GlcNHglycan	238	241	PF01048	0.553
MOD_GlcNHglycan	248	251	PF01048	0.520
MOD_GlcNHglycan	375	378	PF01048	0.556
MOD_GlcNHglycan	72	75	PF01048	0.433
MOD_GlcNHglycan	79	82	PF01048	0.382
MOD_GSK3_1	14	21	PF00069	0.395
MOD_GSK3_1	213	220	PF00069	0.593
MOD_GSK3_1	223	230	PF00069	0.552
MOD_GSK3_1	344	351	PF00069	0.598
MOD_GSK3_1	94	101	PF00069	0.580
MOD_NEK2_1	117	122	PF00069	0.455
MOD_NEK2_1	18	23	PF00069	0.399
MOD_NEK2_1	2	7	PF00069	0.600
MOD_NEK2_1	213	218	PF00069	0.557
MOD_NEK2_1	392	397	PF00069	0.667
MOD_NEK2_1	76	81	PF00069	0.550
MOD_NEK2_2	260	265	PF00069	0.501
MOD_NEK2_2	36	41	PF00069	0.396
MOD_PIKK_1	392	398	PF00454	0.614
MOD_PK_1	94	100	PF00069	0.504
MOD_PKA_1	278	284	PF00069	0.579
MOD_PKA_1	373	379	PF00069	0.561
MOD_PKA_2	107	113	PF00069	0.529
MOD_PKA_2	213	219	PF00069	0.576
MOD_PKA_2	277	283	PF00069	0.581
MOD_PKA_2	291	297	PF00069	0.544
MOD_PKA_2	93	99	PF00069	0.428
MOD_PKB_1	197	205	PF00069	0.570
MOD_PKB_1	276	284	PF00069	0.580
MOD_PKB_1	359	367	PF00069	0.589
MOD_Plk_1	234	240	PF00069	0.564
MOD_Plk_2-3	344	350	PF00069	0.597
MOD_Plk_4	14	20	PF00069	0.391
MOD_Plk_4	82	88	PF00069	0.377
MOD_ProDKin_1	133	139	PF00069	0.540
MOD_ProDKin_1	156	162	PF00069	0.632
MOD_ProDKin_1	21	27	PF00069	0.468
MOD_ProDKin_1	308	314	PF00069	0.640
MOD_SUMO_rev_2	85	93	PF00179	0.379
TRG_ER_diArg_1	196	199	PF00400	0.581
TRG_ER_diArg_1	212	215	PF00400	0.608
TRG_ER_diArg_1	273	276	PF00400	0.598
TRG_ER_diArg_1	331	334	PF00400	0.642
TRG_ER_diArg_1	357	360	PF00400	0.632
TRG_ER_diArg_1	378	381	PF00400	0.688
TRG_NLS_Bipartite_1	192	214	PF00514	0.594
TRG_NLS_MonoCore_2	164	169	PF00514	0.560
TRG_NLS_MonoCore_2	203	208	PF00514	0.499
TRG_NLS_MonoExtC_3	160	165	PF00514	0.576
TRG_NLS_MonoExtC_3	209	214	PF00514	0.659
TRG_NLS_MonoExtC_3	355	360	PF00514	0.578
TRG_NLS_MonoExtN_4	158	165	PF00514	0.578
TRG_NLS_MonoExtN_4	207	214	PF00514	0.675
TRG_Pf-PMV_PEXEL_1	115	119	PF00026	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIK0	Leptomonas seymouri	35%	100%
A4HJ79	Leishmania braziliensis	59%	100%
A4I6M3	Leishmania infantum	99%	100%
E9B1P6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	100%
Q4Q6G4	Leishmania major	84%	97%