Transmembrane amino acid transporter family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid permease 3

Species:

Leishmania donovani

UniProt:

A0A3S7X4A1_LEIDO

TriTrypDb:

LdBPK_310910.1 , LdCL_310015000 , LDHU3_31.1430

Length:

480

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 8
Forrest at al. (procyclic)	no	yes: 10
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 72

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 187
NetGPI	no	yes: 0, no: 188

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	171
GO:0110165	cellular anatomical entity	1	171
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7X4A1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X4A1

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	19
GO:0006810	transport	3	19
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	19
GO:0009987	cellular process	1	19
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	19
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	19
GO:0051234	establishment of localization	2	19
GO:0055085	transmembrane transport	2	19
GO:0071702	organic substance transport	4	19
GO:0071705	nitrogen compound transport	4	19
GO:1903825	organic acid transmembrane transport	3	19
GO:1905039	carboxylic acid transmembrane transport	4	19

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	19
GO:0005342	organic acid transmembrane transporter activity	3	19
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	19
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	19
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	19
GO:0046943	carboxylic acid transmembrane transporter activity	4	19
GO:0003824	catalytic activity	1	7
GO:0016787	hydrolase activity	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	20	24	PF00656	0.706
CLV_C14_Caspase3-7	332	336	PF00656	0.288
CLV_C14_Caspase3-7	53	57	PF00656	0.723
CLV_PCSK_KEX2_1	221	223	PF00082	0.265
CLV_PCSK_PC1ET2_1	221	223	PF00082	0.246
CLV_PCSK_SKI1_1	203	207	PF00082	0.303
CLV_PCSK_SKI1_1	262	266	PF00082	0.551
CLV_PCSK_SKI1_1	301	305	PF00082	0.267
DEG_MDM2_SWIB_1	151	159	PF02201	0.501
DEG_SCF_FBW7_2	181	187	PF00400	0.148
DOC_AGCK_PIF_2	324	329	PF00069	0.392
DOC_CKS1_1	181	186	PF01111	0.304
DOC_CKS1_1	190	195	PF01111	0.249
DOC_MAPK_FxFP_2	429	432	PF00069	0.347
DOC_MAPK_MEF2A_6	141	150	PF00069	0.490
DOC_MAPK_MEF2A_6	227	236	PF00069	0.462
DOC_PP1_RVXF_1	64	71	PF00149	0.659
DOC_PP2B_LxvP_1	407	410	PF13499	0.295
DOC_PP4_FxxP_1	213	216	PF00568	0.245
DOC_PP4_FxxP_1	429	432	PF00568	0.309
DOC_USP7_MATH_1	177	181	PF00917	0.382
DOC_USP7_MATH_1	296	300	PF00917	0.505
DOC_USP7_MATH_1	4	8	PF00917	0.738
DOC_USP7_MATH_1	50	54	PF00917	0.736
DOC_WW_Pin1_4	180	185	PF00397	0.297
DOC_WW_Pin1_4	186	191	PF00397	0.293
LIG_14-3-3_CanoR_1	203	209	PF00244	0.287
LIG_14-3-3_CanoR_1	227	236	PF00244	0.449
LIG_Actin_WH2_2	238	256	PF00022	0.279
LIG_BIR_II_1	1	5	PF00653	0.772
LIG_BRCT_BRCA1_1	288	292	PF00533	0.362
LIG_BRCT_BRCA1_1	83	87	PF00533	0.444
LIG_EH1_1	104	112	PF00400	0.359
LIG_FHA_1	125	131	PF00498	0.316
LIG_FHA_1	181	187	PF00498	0.323
LIG_FHA_1	204	210	PF00498	0.313
LIG_FHA_1	241	247	PF00498	0.339
LIG_FHA_1	285	291	PF00498	0.365
LIG_FHA_1	390	396	PF00498	0.425
LIG_FHA_1	453	459	PF00498	0.292
LIG_FHA_1	71	77	PF00498	0.585
LIG_FHA_2	140	146	PF00498	0.451
LIG_Integrin_RGD_1	258	260	PF01839	0.521
LIG_LIR_Apic_2	73	78	PF02991	0.652
LIG_LIR_Gen_1	113	123	PF02991	0.348
LIG_LIR_Gen_1	142	151	PF02991	0.431
LIG_LIR_Gen_1	207	218	PF02991	0.302
LIG_LIR_Gen_1	455	465	PF02991	0.293
LIG_LIR_Gen_1	473	480	PF02991	0.307
LIG_LIR_LC3C_4	455	460	PF02991	0.427
LIG_LIR_Nem_3	113	119	PF02991	0.329
LIG_LIR_Nem_3	142	146	PF02991	0.470
LIG_LIR_Nem_3	156	161	PF02991	0.476
LIG_LIR_Nem_3	207	213	PF02991	0.294
LIG_LIR_Nem_3	321	327	PF02991	0.298
LIG_LIR_Nem_3	414	419	PF02991	0.237
LIG_LIR_Nem_3	455	460	PF02991	0.297
LIG_LIR_Nem_3	472	478	PF02991	0.349
LIG_LYPXL_SIV_4	173	181	PF13949	0.341
LIG_MLH1_MIPbox_1	288	292	PF16413	0.397
LIG_PDZ_Class_2	475	480	PF00595	0.345
LIG_Pex14_1	164	168	PF04695	0.324
LIG_Pex14_1	452	456	PF04695	0.392
LIG_Pex14_1	75	79	PF04695	0.645
LIG_Pex14_2	151	155	PF04695	0.424
LIG_Pex14_2	277	281	PF04695	0.283
LIG_Pex14_2	320	324	PF04695	0.301
LIG_Pex14_2	431	435	PF04695	0.359
LIG_SH2_CRK	348	352	PF00017	0.297
LIG_SH2_CRK	376	380	PF00017	0.447
LIG_SH2_CRK	79	83	PF00017	0.547
LIG_SH2_STAP1	126	130	PF00017	0.330
LIG_SH2_STAP1	133	137	PF00017	0.470
LIG_SH2_STAT3	291	294	PF00017	0.469
LIG_SH2_STAT5	116	119	PF00017	0.284
LIG_SH2_STAT5	126	129	PF00017	0.306
LIG_SH2_STAT5	157	160	PF00017	0.305
LIG_SH2_STAT5	174	177	PF00017	0.304
LIG_SH2_STAT5	195	198	PF00017	0.250
LIG_SH2_STAT5	228	231	PF00017	0.323
LIG_SH2_STAT5	239	242	PF00017	0.289
LIG_SH2_STAT5	263	266	PF00017	0.250
LIG_SH2_STAT5	291	294	PF00017	0.412
LIG_SH2_STAT5	318	321	PF00017	0.309
LIG_SH2_STAT5	326	329	PF00017	0.314
LIG_SH2_STAT5	353	356	PF00017	0.340
LIG_SH2_STAT5	434	437	PF00017	0.350
LIG_SH2_STAT5	456	459	PF00017	0.287
LIG_SH2_STAT5	475	478	PF00017	0.391
LIG_SH3_3	187	193	PF00018	0.271
LIG_SH3_3	214	220	PF00018	0.403
LIG_SH3_3	341	347	PF00018	0.206
LIG_SUMO_SIM_anti_2	144	150	PF11976	0.529
LIG_SUMO_SIM_anti_2	392	397	PF11976	0.260
LIG_SUMO_SIM_par_1	116	121	PF11976	0.305
LIG_SUMO_SIM_par_1	242	249	PF11976	0.267
LIG_SUMO_SIM_par_1	391	397	PF11976	0.270
LIG_TRAF2_1	142	145	PF00917	0.475
LIG_TYR_ITIM	114	119	PF00017	0.327
LIG_TYR_ITIM	237	242	PF00017	0.313
LIG_TYR_ITIM	77	82	PF00017	0.539
LIG_UBA3_1	181	188	PF00899	0.255
LIG_UBA3_1	350	359	PF00899	0.360
LIG_Vh1_VBS_1	110	128	PF01044	0.334
LIG_WRC_WIRS_1	278	283	PF05994	0.314
LIG_WRC_WIRS_1	475	480	PF05994	0.387
MOD_CK1_1	100	106	PF00069	0.289
MOD_CK1_1	176	182	PF00069	0.325
MOD_CK1_1	189	195	PF00069	0.228
MOD_CK1_1	2	8	PF00069	0.782
MOD_CK1_1	307	313	PF00069	0.312
MOD_CK1_1	411	417	PF00069	0.315
MOD_CK1_1	443	449	PF00069	0.459
MOD_CK1_1	88	94	PF00069	0.361
MOD_CK2_1	139	145	PF00069	0.445
MOD_CK2_1	263	269	PF00069	0.294
MOD_GlcNHglycan	107	110	PF01048	0.442
MOD_GlcNHglycan	175	178	PF01048	0.281
MOD_GlcNHglycan	199	202	PF01048	0.265
MOD_GlcNHglycan	229	232	PF01048	0.308
MOD_GlcNHglycan	265	268	PF01048	0.421
MOD_GlcNHglycan	306	309	PF01048	0.313
MOD_GlcNHglycan	34	37	PF01048	0.547
MOD_GlcNHglycan	438	441	PF01048	0.261
MOD_GSK3_1	135	142	PF00069	0.445
MOD_GSK3_1	163	170	PF00069	0.335
MOD_GSK3_1	173	180	PF00069	0.341
MOD_GSK3_1	436	443	PF00069	0.454
MOD_GSK3_1	44	51	PF00069	0.675
MOD_GSK3_1	470	477	PF00069	0.349
MOD_GSK3_1	81	88	PF00069	0.479
MOD_GSK3_1	97	104	PF00069	0.286
MOD_N-GLC_1	44	49	PF02516	0.554
MOD_N-GLC_1	440	445	PF02516	0.262
MOD_NEK2_1	105	110	PF00069	0.243
MOD_NEK2_1	135	140	PF00069	0.442
MOD_NEK2_1	163	168	PF00069	0.281
MOD_NEK2_1	17	22	PF00069	0.682
MOD_NEK2_1	196	201	PF00069	0.267
MOD_NEK2_1	204	209	PF00069	0.288
MOD_NEK2_1	240	245	PF00069	0.329
MOD_NEK2_1	277	282	PF00069	0.312
MOD_NEK2_1	418	423	PF00069	0.295
MOD_NEK2_1	48	53	PF00069	0.680
MOD_NEK2_1	70	75	PF00069	0.558
MOD_NEK2_2	272	277	PF00069	0.329
MOD_PIKK_1	330	336	PF00454	0.277
MOD_PK_1	222	228	PF00069	0.491
MOD_PKA_2	296	302	PF00069	0.456
MOD_PKA_2	70	76	PF00069	0.592
MOD_Plk_1	144	150	PF00069	0.553
MOD_Plk_1	440	446	PF00069	0.455
MOD_Plk_4	110	116	PF00069	0.292
MOD_Plk_4	121	127	PF00069	0.297
MOD_Plk_4	144	150	PF00069	0.470
MOD_Plk_4	17	23	PF00069	0.681
MOD_Plk_4	177	183	PF00069	0.330
MOD_Plk_4	204	210	PF00069	0.306
MOD_Plk_4	240	246	PF00069	0.313
MOD_Plk_4	272	278	PF00069	0.327
MOD_Plk_4	286	292	PF00069	0.343
MOD_Plk_4	333	339	PF00069	0.241
MOD_Plk_4	399	405	PF00069	0.298
MOD_Plk_4	452	458	PF00069	0.307
MOD_Plk_4	470	476	PF00069	0.257
MOD_ProDKin_1	180	186	PF00069	0.297
MOD_ProDKin_1	189	195	PF00069	0.284
MOD_SUMO_rev_2	255	264	PF00179	0.359
TRG_DiLeu_BaEn_1	144	149	PF01217	0.514
TRG_DiLeu_BaLyEn_6	200	205	PF01217	0.259
TRG_ENDOCYTIC_2	116	119	PF00928	0.312
TRG_ENDOCYTIC_2	239	242	PF00928	0.315
TRG_ENDOCYTIC_2	326	329	PF00928	0.292
TRG_ENDOCYTIC_2	348	351	PF00928	0.313
TRG_ENDOCYTIC_2	353	356	PF00928	0.311
TRG_ENDOCYTIC_2	376	379	PF00928	0.454
TRG_ENDOCYTIC_2	434	437	PF00928	0.420
TRG_ENDOCYTIC_2	456	459	PF00928	0.290
TRG_ENDOCYTIC_2	475	478	PF00928	0.323
TRG_ENDOCYTIC_2	79	82	PF00928	0.548
TRG_ER_diArg_1	295	298	PF00400	0.433

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	38%	98%
A0A0N0P5D2	Leptomonas seymouri	41%	100%
A0A0N0P613	Leptomonas seymouri	25%	100%
A0A0N0P6F5	Leptomonas seymouri	22%	100%
A0A0N0P6F6	Leptomonas seymouri	38%	99%
A0A0N0P8T9	Leptomonas seymouri	39%	96%
A0A0N0P955	Leptomonas seymouri	40%	100%
A0A0N1I2L5	Leptomonas seymouri	74%	100%
A0A0N1I3F8	Leptomonas seymouri	48%	90%
A0A0N1I3H4	Leptomonas seymouri	42%	87%
A0A0N1I8K7	Leptomonas seymouri	60%	98%
A0A0N1I8W4	Leptomonas seymouri	31%	98%
A0A0N1I9T3	Leptomonas seymouri	40%	100%
A0A0N1IAJ0	Leptomonas seymouri	22%	100%
A0A0N1IMP2	Leptomonas seymouri	43%	95%
A0A0N1PA98	Leptomonas seymouri	30%	78%
A0A0N1PBP2	Leptomonas seymouri	38%	97%
A0A0N1PFD1	Leptomonas seymouri	45%	96%
A0A0S4IV32	Bodo saltans	23%	98%
A0A0S4JBX6	Bodo saltans	24%	90%
A0A0S4JHM8	Bodo saltans	26%	100%
A0A0S4JPU4	Bodo saltans	21%	98%
A0A0S4JQ87	Bodo saltans	30%	100%
A0A0S4JU02	Bodo saltans	37%	99%
A0A1X0NJR7	Trypanosomatidae	42%	97%
A0A1X0NKS5	Trypanosomatidae	39%	100%
A0A1X0NKV2	Trypanosomatidae	47%	96%
A0A1X0NKW7	Trypanosomatidae	41%	100%
A0A1X0NLA5	Trypanosomatidae	21%	100%
A0A1X0NNX9	Trypanosomatidae	41%	100%
A0A1X0NPV3	Trypanosomatidae	47%	100%
A0A1X0NQH3	Trypanosomatidae	43%	100%
A0A1X0NR26	Trypanosomatidae	48%	100%
A0A1X0NRL3	Trypanosomatidae	43%	100%
A0A1X0NRL7	Trypanosomatidae	42%	100%
A0A1X0NYI3	Trypanosomatidae	43%	97%
A0A1X0P4S1	Trypanosomatidae	23%	100%
A0A1X0P814	Trypanosomatidae	52%	98%
A0A1X0P9N8	Trypanosomatidae	28%	100%
A0A3Q8ICL1	Leishmania donovani	30%	100%
A0A3Q8ID74	Leishmania donovani	39%	100%
A0A3Q8IDG8	Leishmania donovani	42%	100%
A0A3Q8IEP8	Leishmania donovani	44%	100%
A0A3Q8IFZ0	Leishmania donovani	38%	100%
A0A3Q8IG00	Leishmania donovani	41%	100%
A0A3Q8IGE6	Leishmania donovani	34%	82%
A0A3Q8IHG8	Leishmania donovani	44%	100%
A0A3Q8IJH2	Leishmania donovani	44%	100%
A0A3Q8IJX8	Leishmania donovani	100%	100%
A0A3Q8ILE0	Leishmania donovani	38%	100%
A0A3Q8IN54	Leishmania donovani	25%	100%
A0A3Q8IQG8	Leishmania donovani	29%	100%
A0A3R7JSA0	Trypanosoma rangeli	41%	100%
A0A3R7KDS3	Trypanosoma rangeli	42%	100%
A0A3R7MWF1	Trypanosoma rangeli	22%	100%
A0A3R7N1H9	Trypanosoma rangeli	38%	98%
A0A3R7N2A2	Trypanosoma rangeli	47%	100%
A0A3R7R2W8	Trypanosoma rangeli	45%	100%
A0A3R7RFB5	Trypanosoma rangeli	41%	95%
A0A3R7RQX3	Trypanosoma rangeli	44%	100%
A0A3S5H6T4	Leishmania donovani	39%	100%
A0A3S5H7P4	Leishmania donovani	45%	100%
A0A3S5ISG3	Trypanosoma rangeli	42%	97%
A0A3S7WQ39	Leishmania donovani	39%	100%
A0A3S7X443	Leishmania donovani	44%	100%
A0A3S7X458	Leishmania donovani	44%	100%
A0A3S7X4L2	Leishmania donovani	33%	79%
A0A3S7X4N4	Leishmania donovani	34%	79%
A0A3S7X4P0	Leishmania donovani	33%	79%
A0A3S7XA86	Leishmania donovani	23%	100%
A0A3S7XCE3	Leishmania donovani	22%	100%
A0A422MW74	Trypanosoma rangeli	40%	94%
A0A422N5W8	Trypanosoma rangeli	25%	100%
A0A422N608	Trypanosoma rangeli	40%	98%
A0A422NBM3	Trypanosoma rangeli	43%	100%
A0A422NBQ2	Trypanosoma rangeli	46%	100%
A0A422NZS1	Trypanosoma rangeli	43%	100%
A1YG32	Pan paniscus	22%	95%
A2VCW5	Rattus norvegicus	21%	100%
A2VE31	Bos taurus	22%	95%
A4H565	Leishmania braziliensis	40%	100%
A4HC75	Leishmania braziliensis	37%	100%
A4HFJ2	Leishmania braziliensis	41%	100%
A4HFT5	Leishmania braziliensis	43%	100%
A4HJ06	Leishmania braziliensis	40%	100%
A4HJ07	Leishmania braziliensis	38%	100%
A4HJ09	Leishmania braziliensis	39%	100%
A4HJ10	Leishmania braziliensis	43%	100%
A4HJ35	Leishmania braziliensis	43%	100%
A4HJ36	Leishmania braziliensis	47%	100%
A4HJ37	Leishmania braziliensis	42%	100%
A4HJ63	Leishmania braziliensis	81%	100%
A4HJF8	Leishmania braziliensis	33%	78%
A4HJF9	Leishmania braziliensis	32%	82%
A4HJG1	Leishmania braziliensis	31%	82%
A4HJG3	Leishmania braziliensis	33%	78%
A4HJG5	Leishmania braziliensis	33%	78%
A4HKQ7	Leishmania braziliensis	40%	100%
A4HNJ6	Leishmania braziliensis	24%	100%
A4HNJ7	Leishmania braziliensis	24%	100%
A4HNQ0	Leishmania braziliensis	30%	100%
A4HTE2	Leishmania infantum	39%	100%
A4HZQ0	Leishmania infantum	38%	100%
A4I2V2	Leishmania infantum	38%	81%
A4I6F1	Leishmania infantum	45%	100%
A4I6F2	Leishmania infantum	44%	100%
A4I6I1	Leishmania infantum	99%	100%
A4I6J8	Leishmania infantum	38%	100%
A4I6J9	Leishmania infantum	44%	100%
A4I6K0	Leishmania infantum	42%	100%
A4I6L3	Leishmania infantum	41%	100%
A4I6L4	Leishmania infantum	100%	100%
A4I6W4	Leishmania infantum	33%	79%
A4I887	Leishmania infantum	44%	100%
A4IC53	Leishmania infantum	23%	100%
A4IC66	Leishmania infantum	24%	100%
A4ICC3	Leishmania infantum	22%	100%
A4ICU5	Leishmania infantum	29%	100%
A6NNN8	Homo sapiens	21%	100%
A7E3U5	Bos taurus	21%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	98%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	98%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	99%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	92%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	89%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	91%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	88%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	97%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	97%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	83%
E9AD44	Leishmania major	44%	100%
E9AD45	Leishmania major	38%	100%
E9ADD7	Leishmania major	43%	100%
E9AG08	Leishmania major	24%	100%
E9AG09	Leishmania major	24%	97%
E9AHD7	Leishmania infantum	44%	100%
E9AHD9	Leishmania infantum	39%	100%
E9AHK8	Leishmania infantum	39%	100%
E9AHL1	Leishmania infantum	30%	100%
E9AHL2	Leishmania infantum	33%	100%
E9AHL3	Leishmania infantum	30%	100%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	99%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	79%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
F4IZW8	Arabidopsis thaliana	23%	91%
F4KBM7	Arabidopsis thaliana	23%	100%
G3UVW3	Mus musculus	21%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
O80668	Arabidopsis thaliana	24%	90%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	20%	100%
Q1PER9	Arabidopsis thaliana	23%	92%
Q28HE5	Xenopus tropicalis	22%	100%
Q28I47	Xenopus tropicalis	22%	100%
Q3U1J0	Mus musculus	22%	100%
Q4Q072	Leishmania major	23%	100%
Q4Q236	Leishmania major	30%	100%
Q4Q509	Leishmania major	42%	100%
Q4Q680	Leishmania major	30%	100%
Q4Q682	Leishmania major	33%	82%
Q4Q683	Leishmania major	31%	100%
Q4Q6H5	Leishmania major	95%	100%
Q4Q6K5	Leishmania major	43%	100%
Q4Q6K6	Leishmania major	41%	100%
Q4Q6M8	Leishmania major	43%	100%
Q4Q6M9	Leishmania major	44%	100%
Q4Q6N0	Leishmania major	44%	100%
Q4Q6N1	Leishmania major	38%	100%
Q4QBX3	Leishmania major	39%	100%
Q4QIH0	Leishmania major	37%	100%
Q503G8	Danio rerio	21%	100%
Q5E9S9	Bos taurus	22%	100%
Q5F468	Gallus gallus	21%	96%
Q5HZH7	Mus musculus	21%	100%
Q5R443	Pongo abelii	21%	99%
Q5R9F5	Pongo abelii	21%	100%
Q5SPB1	Danio rerio	23%	95%
Q5XH90	Xenopus tropicalis	21%	97%
Q6DEL1	Danio rerio	23%	100%
Q6DFE7	Xenopus laevis	22%	100%
Q6JWR2	Rattus norvegicus	22%	100%
Q6WWW3	Rattus norvegicus	20%	100%
Q8BWH0	Mus musculus	22%	100%
Q8CFE6	Mus musculus	21%	95%
Q8GYS4	Arabidopsis thaliana	24%	87%
Q8IZM9	Homo sapiens	22%	100%
Q8K2P7	Mus musculus	20%	99%
Q8WUX1	Homo sapiens	22%	100%
Q96QD8	Homo sapiens	22%	95%
Q99624	Homo sapiens	21%	95%
Q9DCP2	Mus musculus	21%	95%
Q9H2H9	Homo sapiens	21%	99%
Q9JHZ9	Rattus norvegicus	21%	95%
Q9JM15	Rattus norvegicus	21%	99%
Q9LI61	Arabidopsis thaliana	22%	100%
Q9LYM2	Arabidopsis thaliana	23%	100%
Q9M8L9	Arabidopsis thaliana	21%	98%
Q9NVC3	Homo sapiens	21%	100%
Q9SF09	Arabidopsis thaliana	22%	100%
Q9SVG0	Arabidopsis thaliana	22%	100%
Q9VT04	Drosophila melanogaster	22%	100%
V5AXD0	Trypanosoma cruzi	22%	100%
V5AZP2	Trypanosoma cruzi	46%	79%
V5B9A6	Trypanosoma cruzi	45%	100%
V5BA72	Trypanosoma cruzi	42%	100%
V5BH70	Trypanosoma cruzi	36%	100%
V5BIJ1	Trypanosoma cruzi	39%	86%
V5BMG4	Trypanosoma cruzi	44%	100%
V5BTX5	Trypanosoma cruzi	25%	95%
V5D7K9	Trypanosoma cruzi	40%	100%
V5DCG4	Trypanosoma cruzi	45%	100%
V5DKR4	Trypanosoma cruzi	44%	100%